Rattus norvegicus

0 known processes

Sorcs3

sortilin-related VPS10 domain containing receptor 3

Sorcs3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.272
behavior GO:0007610 205 0.228
Mouse
defecation GO:0030421 1 0.151
central nervous system development GO:0007417 311 0.148
acid secretion GO:0046717 48 0.140
regulation of signal transduction GO:0009966 318 0.133
g protein coupled receptor signaling pathway GO:0007186 242 0.132
multi organism reproductive process GO:0044703 262 0.127
reproductive process GO:0022414 372 0.114
sexual reproduction GO:0019953 148 0.114
ion transmembrane transport GO:0034220 365 0.112
cation transport GO:0006812 382 0.107
neurological system process GO:0050877 219 0.102
Mouse
cognition GO:0050890 92 0.102
Mouse
cellular component biogenesis GO:0044085 368 0.098
negative regulation of metabolic process GO:0009892 331 0.097
rna biosynthetic process GO:0032774 380 0.096
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.095
negative regulation of cellular metabolic process GO:0031324 281 0.090
cell cell signaling GO:0007267 335 0.089
regulation of phosphate metabolic process GO:0019220 349 0.080
muscle system process GO:0003012 115 0.080
mapk cascade GO:0000165 140 0.076
neuron differentiation GO:0030182 368 0.076
response to alkaloid GO:0043279 132 0.075
glutamate receptor signaling pathway GO:0007215 43 0.075
organonitrogen compound biosynthetic process GO:1901566 167 0.073
cellular response to endogenous stimulus GO:0071495 377 0.073
regulation of molecular function GO:0065009 398 0.071
cellular response to organic cyclic compound GO:0071407 202 0.071
positive regulation of phosphate metabolic process GO:0045937 262 0.070
regulation of phosphorus metabolic process GO:0051174 349 0.067
organic acid transport GO:0015849 116 0.066
regulation of cellular component organization GO:0051128 368 0.066
heart contraction GO:0060047 57 0.065
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.064
purine ribonucleotide biosynthetic process GO:0009152 81 0.061
positive regulation of phosphorylation GO:0042327 177 0.061
kidney development GO:0001822 67 0.061
cellular component assembly GO:0022607 360 0.061
response to glucocorticoid GO:0051384 223 0.059
single organism reproductive process GO:0044702 297 0.058
response to peptide GO:1901652 292 0.057
somatostatin receptor signaling pathway GO:0038169 4 0.056
multicellular organismal reproductive process GO:0048609 233 0.056
organic anion transport GO:0015711 132 0.055
transcription dna templated GO:0006351 377 0.054
cellular ion homeostasis GO:0006873 184 0.052
cellular response to steroid hormone stimulus GO:0071383 93 0.051
positive regulation of signaling GO:0023056 270 0.051
transcription from rna polymerase ii promoter GO:0006366 252 0.051
positive regulation of cell proliferation GO:0008284 249 0.050
amino acid transport GO:0006865 70 0.049
nucleic acid templated transcription GO:0097659 379 0.049
cellular cation homeostasis GO:0030003 180 0.048
cellular response to lipid GO:0071396 201 0.046
muscle contraction GO:0006936 88 0.046
metal ion transport GO:0030001 289 0.045
urogenital system development GO:0001655 78 0.045
carboxylic acid transport GO:0046942 115 0.045
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.044
nucleobase containing small molecule metabolic process GO:0055086 316 0.044
regulation of nucleic acid templated transcription GO:1903506 380 0.044
renal system development GO:0072001 67 0.044
synaptic transmission GO:0007268 235 0.043
intracellular signal transduction GO:0035556 314 0.043
learning or memory GO:0007611 90 0.043
Mouse
negative regulation of cellular biosynthetic process GO:0031327 161 0.043
purine nucleotide metabolic process GO:0006163 229 0.043
blood circulation GO:0008015 183 0.042
positive regulation of rna metabolic process GO:0051254 203 0.042
regulation of glutamate receptor signaling pathway GO:1900449 17 0.042
head development GO:0060322 247 0.042
negative regulation of nucleic acid templated transcription GO:1903507 117 0.041
response to corticosteroid GO:0031960 235 0.041
single organism biosynthetic process GO:0044711 342 0.041
programmed cell death GO:0012501 392 0.041
negative regulation of cell death GO:0060548 229 0.040
purine containing compound metabolic process GO:0072521 253 0.040
localization of cell GO:0051674 202 0.039
regulation of phosphorylation GO:0042325 248 0.039
positive regulation of response to stimulus GO:0048584 285 0.039
regulation of ion transmembrane transport GO:0034765 121 0.038
locomotion GO:0040011 237 0.038
axon development GO:0061564 96 0.038
cation transmembrane transport GO:0098655 263 0.037
negative regulation of gene expression GO:0010629 199 0.037
calcium ion homeostasis GO:0055074 162 0.037
rna metabolic process GO:0016070 406 0.037
regulation of multicellular organismal development GO:2000026 376 0.036
forebrain development GO:0030900 98 0.036
brain development GO:0007420 247 0.035
regulation of membrane potential GO:0042391 110 0.035
feeding behavior GO:0007631 53 0.035
regulation of rna biosynthetic process GO:2001141 381 0.035
dicarboxylic acid transport GO:0006835 34 0.035
response to decreased oxygen levels GO:0036293 237 0.035
camp metabolic process GO:0046058 63 0.035
cellular response to glucocorticoid stimulus GO:0071385 68 0.035
positive regulation of phosphorus metabolic process GO:0010562 262 0.034
regulation of protein metabolic process GO:0051246 289 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.034
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.034
protein phosphorylation GO:0006468 345 0.034
regulation of ion transport GO:0043269 245 0.034
anatomical structure morphogenesis GO:0009653 298 0.033
nucleoside phosphate metabolic process GO:0006753 283 0.033
ion homeostasis GO:0050801 212 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.033
neuropeptide signaling pathway GO:0007218 29 0.033
regulation of transmembrane transport GO:0034762 122 0.033
cellular response to corticosteroid stimulus GO:0071384 69 0.033
reproduction GO:0000003 245 0.033
learning GO:0007612 33 0.033
Mouse
negative regulation of biosynthetic process GO:0009890 168 0.033
negative regulation of cell communication GO:0010648 158 0.033
Mouse
regulation of rna metabolic process GO:0051252 391 0.032
response to oxygen levels GO:0070482 265 0.032
cellular homeostasis GO:0019725 252 0.032
purine containing compound biosynthetic process GO:0072522 85 0.032
regulation of catalytic activity GO:0050790 304 0.032
ribose phosphate biosynthetic process GO:0046390 87 0.032
regulation of muscle contraction GO:0006937 53 0.032
regulation of ion transmembrane transporter activity GO:0032412 48 0.031
aging GO:0007568 241 0.031
regulation of transporter activity GO:0032409 50 0.031
nucleotide metabolic process GO:0009117 279 0.031
negative regulation of rna metabolic process GO:0051253 123 0.031
nucleoside phosphate biosynthetic process GO:1901293 102 0.031
single organism behavior GO:0044708 130 0.030
Mouse
neuron projection development GO:0031175 273 0.030
cellular chemical homeostasis GO:0055082 247 0.030
negative regulation of transcription dna templated GO:0045892 116 0.030
response to extracellular stimulus GO:0009991 380 0.030
regulation of transmembrane transporter activity GO:0022898 49 0.030
excretion GO:0007588 24 0.030
response to ammonium ion GO:0060359 71 0.030
regulation of nucleotide metabolic process GO:0006140 117 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
cyclic purine nucleotide metabolic process GO:0052652 62 0.029
protein complex assembly GO:0006461 263 0.029
cellular response to abiotic stimulus GO:0071214 85 0.029
motor neuron axon guidance GO:0008045 1 0.029
regulation of nervous system development GO:0051960 264 0.029
positive regulation of cell communication GO:0010647 271 0.028
tissue development GO:0009888 252 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
macromolecular complex subunit organization GO:0043933 339 0.028
anion transport GO:0006820 178 0.028
positive regulation of intracellular signal transduction GO:1902533 138 0.028
cellular response to hormone stimulus GO:0032870 247 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
organic acid metabolic process GO:0006082 292 0.027
cation homeostasis GO:0055080 195 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
sensory organ development GO:0007423 74 0.026
multi multicellular organism process GO:0044706 138 0.026
carbohydrate derivative biosynthetic process GO:1901137 124 0.026
camp biosynthetic process GO:0006171 47 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
purine nucleotide biosynthetic process GO:0006164 83 0.025
chemical homeostasis GO:0048878 292 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
nitrogen compound transport GO:0071705 229 0.025
regulation of neurogenesis GO:0050767 247 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
cyclic nucleotide metabolic process GO:0009187 80 0.024
cellular calcium ion homeostasis GO:0006874 160 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
response to ethanol GO:0045471 162 0.023
regulation of hormone levels GO:0010817 187 0.023
positive regulation of nervous system development GO:0051962 178 0.023
negative regulation of secretion GO:0051048 82 0.023
protein oligomerization GO:0051259 191 0.023
multicellular organism reproduction GO:0032504 233 0.023
positive regulation of gene expression GO:0010628 244 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.022
protein complex biogenesis GO:0070271 263 0.022
negative regulation of transport GO:0051051 136 0.022
cell part morphogenesis GO:0032990 123 0.022
regulation of saliva secretion GO:0046877 3 0.022
nucleotide biosynthetic process GO:0009165 98 0.022
neuron apoptotic process GO:0051402 88 0.022
regulation of secretion GO:0051046 224 0.022
cellular response to growth factor stimulus GO:0071363 162 0.021
neuron development GO:0048666 286 0.021
regulation of camp biosynthetic process GO:0030817 38 0.021
developmental process involved in reproduction GO:0003006 159 0.021
response to hypoxia GO:0001666 231 0.021
regulation of muscle system process GO:0090257 79 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
negative regulation of adenylate cyclase activity GO:0007194 7 0.021
neuron death GO:0070997 127 0.021
glutamate secretion GO:0014047 19 0.021
positive regulation of protein modification process GO:0031401 142 0.021
cell projection morphogenesis GO:0048858 123 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
regulation of cell differentiation GO:0045595 320 0.020
reproductive system development GO:0061458 128 0.020
response to ketone GO:1901654 182 0.020
second messenger mediated signaling GO:0019932 51 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
response to growth factor GO:0070848 189 0.020
negative regulation of camp metabolic process GO:0030815 14 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
rhythmic process GO:0048511 156 0.020
anion transmembrane transport GO:0098656 77 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
macromolecule localization GO:0033036 252 0.019
Yeast
organophosphate metabolic process GO:0019637 370 0.019
cell morphogenesis involved in differentiation GO:0000904 119 0.019
cellular catabolic process GO:0044248 295 0.019
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.019
regulation of secretion by cell GO:1903530 208 0.019
response to toxic substance GO:0009636 133 0.018
signal release GO:0023061 145 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
negative regulation of ion transport GO:0043271 51 0.018
regulation of system process GO:0044057 208 0.018
response to estrogen GO:0043627 232 0.018
organic hydroxy compound transport GO:0015850 77 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
negative regulation of cyclic nucleotide metabolic process GO:0030800 15 0.018
positive regulation of signal transduction GO:0009967 175 0.018
heart morphogenesis GO:0003007 3 0.017
negative regulation of neurogenesis GO:0050768 78 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
regulation of cellular localization GO:0060341 263 0.017
negative regulation of glutamate secretion GO:0014050 9 0.017
adult locomotory behavior GO:0008344 4 0.017
peptide transport GO:0015833 97 0.017
negative regulation of molecular function GO:0044092 133 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
neuron neuron synaptic transmission GO:0007270 60 0.017
cellular component movement GO:0006928 248 0.017
regulation of apoptotic process GO:0042981 335 0.017
apoptotic process GO:0006915 381 0.017
gonad development GO:0008406 104 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
multicellular organismal response to stress GO:0033555 25 0.017
sensory perception of pain GO:0019233 73 0.017
secretion GO:0046903 307 0.017
small gtpase mediated signal transduction GO:0007264 36 0.016
regulation of cell proliferation GO:0042127 359 0.016
response to peptide hormone GO:0043434 278 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.016
regulation of cell development GO:0060284 263 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
regulation of cellular component biogenesis GO:0044087 86 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
positive regulation of synaptic transmission GO:0050806 62 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
epithelial cell differentiation GO:0030855 71 0.016
protein complex subunit organization GO:0071822 302 0.016
response to radiation GO:0009314 137 0.016
cell motility GO:0048870 202 0.016
regulation of kinase activity GO:0043549 117 0.016
negative regulation of hormone secretion GO:0046888 46 0.016
cell projection organization GO:0030030 302 0.016
homeostatic process GO:0042592 331 0.015
response to acid chemical GO:0001101 222 0.015
memory GO:0007613 54 0.015
Mouse
regulation of transferase activity GO:0051338 123 0.015
response to estradiol GO:0032355 164 0.015
regulation of transcription dna templated GO:0006355 374 0.015
sex differentiation GO:0007548 113 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
anterior posterior pattern specification GO:0009952 1 0.015
peptide secretion GO:0002790 86 0.015
regulation of neuronal synaptic plasticity GO:0048168 31 0.015
oxoacid metabolic process GO:0043436 290 0.015
cellular amine metabolic process GO:0044106 38 0.015
epithelium development GO:0060429 96 0.015
calcium ion transport GO:0006816 131 0.015
embryonic pattern specification GO:0009880 1 0.015
regulation of mapk cascade GO:0043408 116 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
sodium ion transmembrane transport GO:0035725 67 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
protein localization GO:0008104 191 0.015
Yeast
negative regulation of secretion by cell GO:1903531 72 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
tube development GO:0035295 89 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
regulation of behavior GO:0050795 61 0.014
potassium ion homeostasis GO:0055075 2 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
telencephalon development GO:0021537 62 0.014
growth GO:0040007 165 0.014
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
cell cycle GO:0007049 101 0.014
smooth muscle contraction GO:0006939 37 0.014
development of primary sexual characteristics GO:0045137 107 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
regulation of programmed cell death GO:0043067 341 0.013
male gonad development GO:0008584 59 0.013
axis specification GO:0009798 4 0.013
response to electrical stimulus GO:0051602 56 0.013
rhythmic synaptic transmission GO:0060024 1 0.013
development of primary male sexual characteristics GO:0046546 59 0.013
catabolic process GO:0009056 351 0.013
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.013
regulation of heart contraction GO:0008016 48 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
regulation of protein modification process GO:0031399 194 0.013
peristalsis GO:0030432 2 0.013
palate development GO:0060021 2 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
phenol containing compound metabolic process GO:0018958 30 0.013
heart process GO:0003015 57 0.013
phasic smooth muscle contraction GO:0014821 3 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
positive regulation of transferase activity GO:0051347 81 0.013
monocarboxylic acid transport GO:0015718 52 0.013
response to nutrient levels GO:0031667 370 0.013
cell migration GO:0016477 197 0.013
cyclic nucleotide biosynthetic process GO:0009190 63 0.012
mechanoreceptor differentiation GO:0042490 2 0.012
circulatory system process GO:0003013 183 0.012
response to pain GO:0048265 11 0.012
positive regulation of transport GO:0051050 245 0.012
regulation of neuron death GO:1901214 115 0.012
circadian rhythm GO:0007623 88 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
regulation of blood circulation GO:1903522 110 0.012
cell morphogenesis GO:0000902 142 0.012
negative regulation of signaling GO:0023057 157 0.012
Mouse
positive regulation of molecular function GO:0044093 230 0.012
sensory perception GO:0007600 101 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
embryonic axis specification GO:0000578 1 0.012
metal ion homeostasis GO:0055065 186 0.012
regulation of metal ion transport GO:0010959 118 0.012
somatostatin signaling pathway GO:0038170 4 0.012
response to morphine GO:0043278 27 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.012
axonogenesis GO:0007409 71 0.012
protein autophosphorylation GO:0046777 66 0.012
cellular ketone metabolic process GO:0042180 51 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
activation of protein kinase activity GO:0032147 47 0.011
organ morphogenesis GO:0009887 75 0.011
insulin secretion GO:0030073 69 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
limbic system development GO:0021761 38 0.011
negative regulation of cytosolic calcium ion concentration GO:0051481 10 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
embryo development GO:0009790 49 0.011
regulation of cell projection organization GO:0031344 175 0.011
circulatory system development GO:0072359 134 0.011
immune system process GO:0002376 204 0.011
regulation of lyase activity GO:0051339 22 0.011
negative regulation of cell development GO:0010721 82 0.011
hormone transport GO:0009914 121 0.011
protein transport GO:0015031 132 0.011
Yeast
macromolecular complex assembly GO:0065003 273 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
divalent inorganic cation transport GO:0072511 134 0.011
small molecule catabolic process GO:0044282 59 0.011
regulation of peptide secretion GO:0002791 82 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
regulation of protein kinase activity GO:0045859 105 0.011
gamete generation GO:0007276 124 0.011
rna localization GO:0006403 4 0.011
female pregnancy GO:0007565 122 0.011
sodium ion homeostasis GO:0055078 23 0.010
negative regulation of purine nucleotide biosynthetic process GO:1900372 12 0.010
nucleoside metabolic process GO:0009116 179 0.010
ras protein signal transduction GO:0007265 29 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
protein heterooligomerization GO:0051291 89 0.010
cellular component morphogenesis GO:0032989 155 0.010
gastrulation GO:0007369 2 0.010
regulation of camp metabolic process GO:0030814 43 0.010
organelle organization GO:0006996 266 0.010
regulation of ossification GO:0030278 32 0.010

Sorcs3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.010
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010