Rattus norvegicus

0 known processes

Spg20

spastic paraplegia 20 (Troyer syndrome) homolog (human)

Spg20 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cell projection organization GO:0030030 302 0.082
neuron development GO:0048666 286 0.070
regulation of molecular function GO:0065009 398 0.065
protein phosphorylation GO:0006468 345 0.062
positive regulation of nervous system development GO:0051962 178 0.061
regulation of system process GO:0044057 208 0.057
amine metabolic process GO:0009308 38 0.047
regulation of neurogenesis GO:0050767 247 0.047
muscle system process GO:0003012 115 0.047
regulation of protein metabolic process GO:0051246 289 0.044
positive regulation of cell differentiation GO:0045597 217 0.039
regulation of cell differentiation GO:0045595 320 0.037
positive regulation of cell communication GO:0010647 271 0.037
positive regulation of cell development GO:0010720 176 0.037
regulation of nervous system development GO:0051960 264 0.035
positive regulation of neurogenesis GO:0050769 165 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
regulation of cellular amine metabolic process GO:0033238 8 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
regulation of neuron differentiation GO:0045664 208 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
oxoacid metabolic process GO:0043436 290 0.032
regulation of cell development GO:0060284 263 0.032
localization of cell GO:0051674 202 0.032
central nervous system development GO:0007417 311 0.032
cellular response to organic cyclic compound GO:0071407 202 0.032
regulation of cell projection organization GO:0031344 175 0.031
cell cell signaling GO:0007267 335 0.031
regulation of cell proliferation GO:0042127 359 0.030
nucleic acid templated transcription GO:0097659 379 0.030
regulation of response to stress GO:0080134 126 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
regulation of cellular component organization GO:0051128 368 0.029
intracellular signal transduction GO:0035556 314 0.028
cellular amine metabolic process GO:0044106 38 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
catabolic process GO:0009056 351 0.028
organic acid metabolic process GO:0006082 292 0.028
positive regulation of developmental process GO:0051094 283 0.027
neurological system process GO:0050877 219 0.026
neuron projection development GO:0031175 273 0.026
locomotion GO:0040011 237 0.026
cellular component movement GO:0006928 248 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.025
regulation of rna metabolic process GO:0051252 391 0.025
negative regulation of gene expression GO:0010629 199 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
defense response GO:0006952 194 0.025
response to external biotic stimulus GO:0043207 221 0.024
oxidation reduction process GO:0055114 304 0.024
regulation of transcription dna templated GO:0006355 374 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
organic substance catabolic process GO:1901575 316 0.023
positive regulation of transcription factor import into nucleus GO:0042993 4 0.023
multi organism reproductive process GO:0044703 262 0.023
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.023
dna metabolic process GO:0006259 96 0.023
dna packaging GO:0006323 4 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
multicellular organism reproduction GO:0032504 233 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
response to oxygen levels GO:0070482 265 0.023
cellular response to growth factor stimulus GO:0071363 162 0.022
reproductive process GO:0022414 372 0.022
organic acid biosynthetic process GO:0016053 83 0.022
regulation of multicellular organismal development GO:2000026 376 0.021
neuron differentiation GO:0030182 368 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
cell migration GO:0016477 197 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
positive regulation of transport GO:0051050 245 0.020
response to wounding GO:0009611 254 0.020
rna biosynthetic process GO:0032774 380 0.020
cytoplasmic transport GO:0016482 115 0.020
regulation of protein modification process GO:0031399 194 0.020
chemical homeostasis GO:0048878 292 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
single organism intracellular transport GO:1902582 166 0.020
cell cycle checkpoint GO:0000075 2 0.019
rna metabolic process GO:0016070 406 0.019
negative regulation of metabolic process GO:0009892 331 0.019
synaptic transmission GO:0007268 235 0.019
regulation of canonical wnt signaling pathway GO:0060828 4 0.019
regulation of neuron projection development GO:0010975 161 0.019
regulation of cellular localization GO:0060341 263 0.019
cell motility GO:0048870 202 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
regulation of neuron death GO:1901214 115 0.018
negative regulation of cell cycle phase transition GO:1901988 4 0.018
carbohydrate metabolic process GO:0005975 130 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.017
cellular ketone metabolic process GO:0042180 51 0.017
salivary gland morphogenesis GO:0007435 1 0.017
intracellular transport GO:0046907 185 0.017
response to other organism GO:0051707 220 0.017
regulation of membrane potential GO:0042391 110 0.017
salivary gland development GO:0007431 3 0.017
response to hypoxia GO:0001666 231 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
cellular catabolic process GO:0044248 295 0.017
negative regulation of biosynthetic process GO:0009890 168 0.016
ion homeostasis GO:0050801 212 0.016
cellular ion homeostasis GO:0006873 184 0.016
transmembrane transport GO:0055085 412 0.016
cellular homeostasis GO:0019725 252 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
circulatory system process GO:0003013 183 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.015
negative regulation of signaling GO:0023057 157 0.015
carboxylic acid metabolic process GO:0019752 289 0.015
olfactory learning GO:0008355 1 0.015
action potential GO:0001508 54 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
regulation of catalytic activity GO:0050790 304 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
dna integrity checkpoint GO:0031570 2 0.014
regulation of immune system process GO:0002682 123 0.014
metal ion homeostasis GO:0055065 186 0.014
cation transport GO:0006812 382 0.014
regulation of response to external stimulus GO:0032101 106 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
regulation of blood circulation GO:1903522 110 0.014
homeostatic process GO:0042592 331 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.014
dendrite morphogenesis GO:0048813 43 0.014
cell part morphogenesis GO:0032990 123 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
cellular component morphogenesis GO:0032989 155 0.013
response to biotic stimulus GO:0009607 226 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
neuronal action potential GO:0019228 35 0.013
cholesterol homeostasis GO:0042632 3 0.013
cellular chemical homeostasis GO:0055082 247 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
multicellular organismal signaling GO:0035637 44 0.013
response to peptide hormone GO:0043434 278 0.013
response to growth factor GO:0070848 189 0.013
single organism reproductive process GO:0044702 297 0.013
cellular response to external stimulus GO:0071496 118 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
sterol homeostasis GO:0055092 3 0.012
regulation of dendrite development GO:0050773 59 0.012
cognition GO:0050890 92 0.012
negative regulation of signal transduction GO:0009968 83 0.012
nucleotide metabolic process GO:0009117 279 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
tissue development GO:0009888 252 0.012
reproduction GO:0000003 245 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
protein complex subunit organization GO:0071822 302 0.012
response to nutrient levels GO:0031667 370 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of molecular function GO:0044093 230 0.012
cellular component assembly GO:0022607 360 0.012
cell morphogenesis GO:0000902 142 0.011
regulation of kinase activity GO:0043549 117 0.011
organelle organization GO:0006996 266 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
chemosensory behavior GO:0007635 2 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
regulation of intracellular transport GO:0032386 65 0.011
mitotic cell cycle checkpoint GO:0007093 1 0.011
protein complex biogenesis GO:0070271 263 0.011
male gamete generation GO:0048232 99 0.011
negative regulation of viral process GO:0048525 4 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
response to decreased oxygen levels GO:0036293 237 0.011
single organism catabolic process GO:0044712 283 0.011
macromolecule localization GO:0033036 252 0.011
neuron projection morphogenesis GO:0048812 122 0.011
sexual reproduction GO:0019953 148 0.011
olfactory behavior GO:0042048 2 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
regulation of muscle system process GO:0090257 79 0.011
negative regulation of molecular function GO:0044092 133 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
regulation of protein kinase activity GO:0045859 105 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
protein oligomerization GO:0051259 191 0.011
secretion by cell GO:0032940 248 0.011
cellular response to hormone stimulus GO:0032870 247 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
negative regulation of cell communication GO:0010648 158 0.010
response to extracellular stimulus GO:0009991 380 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
protein transport GO:0015031 132 0.010

Spg20 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.021
disease of anatomical entity DOID:7 0 0.021