Rattus norvegicus

0 known processes

Spire1

spire homolog 1 (Drosophila)

Spire1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell projection organization GO:0030030 302 0.302
neuron development GO:0048666 286 0.300
cellular component morphogenesis GO:0032989 155 0.270
regulation of nervous system development GO:0051960 264 0.230
neuron differentiation GO:0030182 368 0.230
cell projection morphogenesis GO:0048858 123 0.227
regulation of phosphate metabolic process GO:0019220 349 0.215
neuron projection morphogenesis GO:0048812 122 0.214
regulation of neurogenesis GO:0050767 247 0.214
neuron projection development GO:0031175 273 0.213
protein localization GO:0008104 191 0.185
cellular component assembly GO:0022607 360 0.161
regulation of neuron projection development GO:0010975 161 0.158
regulation of cellular component organization GO:0051128 368 0.158
regulation of cell differentiation GO:0045595 320 0.157
anatomical structure morphogenesis GO:0009653 298 0.151
cell part morphogenesis GO:0032990 123 0.147
regulation of neuron differentiation GO:0045664 208 0.142
protein phosphorylation GO:0006468 345 0.138
cellular component biogenesis GO:0044085 368 0.135
regulation of signal transduction GO:0009966 318 0.131
macromolecule localization GO:0033036 252 0.123
regulation of intracellular signal transduction GO:1902531 218 0.122
regulation of nucleic acid templated transcription GO:1903506 380 0.121
nucleobase containing small molecule metabolic process GO:0055086 316 0.121
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.120
secretion GO:0046903 307 0.120
single organism biosynthetic process GO:0044711 342 0.115
carbohydrate derivative metabolic process GO:1901135 346 0.115
positive regulation of cellular biosynthetic process GO:0031328 295 0.114
organic acid metabolic process GO:0006082 292 0.113
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.111
intracellular signal transduction GO:0035556 314 0.106
carboxylic acid metabolic process GO:0019752 289 0.103
regulation of phosphorus metabolic process GO:0051174 349 0.103
cellular protein localization GO:0034613 122 0.100
oxoacid metabolic process GO:0043436 290 0.098
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.097
regulation of cell development GO:0060284 263 0.096
cation transport GO:0006812 382 0.096
axon development GO:0061564 96 0.095
regulation of multicellular organismal development GO:2000026 376 0.093
cell migration GO:0016477 197 0.092
regulation of cell projection organization GO:0031344 175 0.091
transcription dna templated GO:0006351 377 0.091
metal ion transport GO:0030001 289 0.091
regulation of cellular protein metabolic process GO:0032268 267 0.091
protein complex assembly GO:0006461 263 0.091
rna biosynthetic process GO:0032774 380 0.090
cellular macromolecule localization GO:0070727 122 0.090
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.089
regulation of molecular function GO:0065009 398 0.087
reproductive process GO:0022414 372 0.085
catabolic process GO:0009056 351 0.083
macromolecular complex subunit organization GO:0043933 339 0.082
establishment of protein localization GO:0045184 141 0.077
positive regulation of biosynthetic process GO:0009891 319 0.076
protein complex subunit organization GO:0071822 302 0.076
dendrite development GO:0016358 72 0.075
tissue development GO:0009888 252 0.075
programmed cell death GO:0012501 392 0.074
apoptotic process GO:0006915 381 0.074
regulation of rna biosynthetic process GO:2001141 381 0.074
positive regulation of multicellular organismal process GO:0051240 387 0.073
locomotion GO:0040011 237 0.073
negative regulation of cell differentiation GO:0045596 99 0.073
cell morphogenesis GO:0000902 142 0.071
ribose phosphate metabolic process GO:0019693 235 0.070
regulation of catalytic activity GO:0050790 304 0.069
behavior GO:0007610 205 0.069
regulation of transcription dna templated GO:0006355 374 0.068
negative regulation of metabolic process GO:0009892 331 0.068
secretion by cell GO:0032940 248 0.068
organelle organization GO:0006996 266 0.068
intracellular transport GO:0046907 185 0.068
synaptic vesicle priming GO:0016082 4 0.067
response to wounding GO:0009611 254 0.067
protein transport GO:0015031 132 0.065
protein complex biogenesis GO:0070271 263 0.065
cell morphogenesis involved in differentiation GO:0000904 119 0.065
single organism organelle organization GO:1902589 180 0.064
rna metabolic process GO:0016070 406 0.063
regulation of cell morphogenesis GO:0022604 77 0.062
organophosphate biosynthetic process GO:0090407 143 0.061
dendrite morphogenesis GO:0048813 43 0.060
cell motility GO:0048870 202 0.059
vesicle mediated transport GO:0016192 181 0.058
negative regulation of developmental process GO:0051093 125 0.057
positive regulation of cellular component organization GO:0051130 200 0.057
ion transmembrane transport GO:0034220 365 0.057
reproduction GO:0000003 245 0.057
regulation of phosphorylation GO:0042325 248 0.056
nucleoside phosphate metabolic process GO:0006753 283 0.056
regulation of rna metabolic process GO:0051252 391 0.055
cellular component movement GO:0006928 248 0.054
positive regulation of developmental process GO:0051094 283 0.054
cellular chemical homeostasis GO:0055082 247 0.053
transmembrane transport GO:0055085 412 0.053
negative regulation of neuron differentiation GO:0045665 62 0.053
cyclic nucleotide metabolic process GO:0009187 80 0.052
cellular amino acid metabolic process GO:0006520 107 0.052
regulation of cellular localization GO:0060341 263 0.052
purine ribonucleotide metabolic process GO:0009150 227 0.052
head development GO:0060322 247 0.051
localization of cell GO:0051674 202 0.050
nucleotide biosynthetic process GO:0009165 98 0.049
single organism catabolic process GO:0044712 283 0.048
positive regulation of neurogenesis GO:0050769 165 0.047
regulation of membrane potential GO:0042391 110 0.047
signal release GO:0023061 145 0.046
response to molecule of bacterial origin GO:0002237 194 0.046
regulation of protein metabolic process GO:0051246 289 0.046
positive regulation of neuron migration GO:2001224 2 0.046
single organism reproductive process GO:0044702 297 0.045
response to oxygen levels GO:0070482 265 0.045
negative regulation of nervous system development GO:0051961 79 0.045
negative regulation of biosynthetic process GO:0009890 168 0.044
positive regulation of nervous system development GO:0051962 178 0.044
purine ribonucleotide biosynthetic process GO:0009152 81 0.043
ribonucleotide biosynthetic process GO:0009260 85 0.043
axonogenesis GO:0007409 71 0.043
positive regulation of transport GO:0051050 245 0.043
regulation of apoptotic process GO:0042981 335 0.043
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
nucleic acid templated transcription GO:0097659 379 0.042
cyclic purine nucleotide metabolic process GO:0052652 62 0.042
nucleotide metabolic process GO:0009117 279 0.042
regulation of dendrite development GO:0050773 59 0.041
cellular response to endogenous stimulus GO:0071495 377 0.041
positive regulation of cell differentiation GO:0045597 217 0.041
ribose phosphate biosynthetic process GO:0046390 87 0.040
carbohydrate derivative biosynthetic process GO:1901137 124 0.040
positive regulation of signaling GO:0023056 270 0.040
regulation of secretion GO:0051046 224 0.040
cell cell signaling GO:0007267 335 0.040
cellular response to stress GO:0033554 269 0.039
multicellular organismal reproductive process GO:0048609 233 0.039
multi organism reproductive process GO:0044703 262 0.039
positive regulation of rna biosynthetic process GO:1902680 197 0.039
regulation of secretion by cell GO:1903530 208 0.038
regulation of cell proliferation GO:0042127 359 0.038
intracellular protein transport GO:0006886 79 0.038
immune system process GO:0002376 204 0.037
purine nucleotide biosynthetic process GO:0006164 83 0.037
homeostatic process GO:0042592 331 0.037
organonitrogen compound biosynthetic process GO:1901566 167 0.037
sexual reproduction GO:0019953 148 0.037
single organism cellular localization GO:1902580 102 0.037
single organism intracellular transport GO:1902582 166 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.037
macromolecular complex assembly GO:0065003 273 0.037
positive regulation of neuron differentiation GO:0045666 126 0.036
negative regulation of multicellular organismal process GO:0051241 203 0.036
central nervous system development GO:0007417 311 0.036
synaptic growth at neuromuscular junction GO:0051124 1 0.036
organic substance catabolic process GO:1901575 316 0.035
organonitrogen compound catabolic process GO:1901565 179 0.035
regulation of protein phosphorylation GO:0001932 183 0.035
organic acid biosynthetic process GO:0016053 83 0.035
cyclic nucleotide biosynthetic process GO:0009190 63 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
positive regulation of cell proliferation GO:0008284 249 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.034
epithelium development GO:0060429 96 0.034
cation transmembrane transport GO:0098655 263 0.034
neurotransmitter transport GO:0006836 42 0.034
regulation of nucleotide biosynthetic process GO:0030808 47 0.033
neurological system process GO:0050877 219 0.033
cellular lipid metabolic process GO:0044255 208 0.033
organophosphate metabolic process GO:0019637 370 0.033
response to hypoxia GO:0001666 231 0.033
membrane organization GO:0061024 94 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
positive regulation of transcription dna templated GO:0045893 197 0.033
brain development GO:0007420 247 0.033
divalent metal ion transport GO:0070838 132 0.033
negative regulation of neurogenesis GO:0050768 78 0.033
regulation of protein modification process GO:0031399 194 0.033
monocarboxylic acid metabolic process GO:0032787 152 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
nucleoside phosphate biosynthetic process GO:1901293 102 0.032
positive regulation of cell development GO:0010720 176 0.032
regulation of purine nucleotide metabolic process GO:1900542 115 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
biological adhesion GO:0022610 110 0.031
positive regulation of rna metabolic process GO:0051254 203 0.031
cytoplasmic transport GO:0016482 115 0.031
inorganic cation transmembrane transport GO:0098662 202 0.031
positive regulation of gene expression GO:0010628 244 0.030
protein localization to organelle GO:0033365 57 0.030
ion homeostasis GO:0050801 212 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
purine containing compound metabolic process GO:0072521 253 0.030
regulation of cellular component movement GO:0051270 150 0.030
inorganic ion transmembrane transport GO:0098660 229 0.029
regulation of synaptic transmission GO:0050804 141 0.029
eye morphogenesis GO:0048592 4 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
regulation of vesicle mediated transport GO:0060627 81 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
defense response GO:0006952 194 0.029
sensory perception GO:0007600 101 0.029
positive regulation of cell communication GO:0010647 271 0.028
positive regulation of catalytic activity GO:0043085 184 0.028
regulation of programmed cell death GO:0043067 341 0.028
response to external biotic stimulus GO:0043207 221 0.028
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.028
response to inorganic substance GO:0010035 377 0.028
negative regulation of signaling GO:0023057 157 0.028
lipid metabolic process GO:0006629 283 0.027
nucleoside phosphate catabolic process GO:1901292 140 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
cation homeostasis GO:0055080 195 0.027
nitrogen compound transport GO:0071705 229 0.027
synapse organization GO:0050808 46 0.027
response to bacterium GO:0009617 200 0.027
potassium ion transport GO:0006813 97 0.027
protein targeting GO:0006605 61 0.027
establishment of protein localization to organelle GO:0072594 44 0.026
positive regulation of molecular function GO:0044093 230 0.026
cellular amine metabolic process GO:0044106 38 0.026
purine ribonucleoside metabolic process GO:0046128 168 0.026
response to extracellular stimulus GO:0009991 380 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
response to carbohydrate GO:0009743 183 0.026
nuclear transport GO:0051169 49 0.025
regulation of ion transport GO:0043269 245 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
gamete generation GO:0007276 124 0.025
camp biosynthetic process GO:0006171 47 0.025
cellular catabolic process GO:0044248 295 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
response to decreased oxygen levels GO:0036293 237 0.024
response to peptide GO:1901652 292 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
alpha amino acid metabolic process GO:1901605 71 0.024
cellular ion homeostasis GO:0006873 184 0.024
positive regulation of signal transduction GO:0009967 175 0.024
spermatogenesis GO:0007283 99 0.024
cellular calcium ion homeostasis GO:0006874 160 0.024
neural crest cell differentiation GO:0014033 2 0.024
response to metal ion GO:0010038 253 0.024
growth GO:0040007 165 0.024
synaptic vesicle transport GO:0048489 23 0.024
regulation of system process GO:0044057 208 0.023
regulation of transferase activity GO:0051338 123 0.023
purine containing compound biosynthetic process GO:0072522 85 0.023
positive regulation of nucleotide metabolic process GO:0045981 91 0.023
neuron projection guidance GO:0097485 24 0.023
regulation of exocytosis GO:0017157 37 0.023
positive regulation of neuron projection development GO:0010976 99 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
response to nutrient levels GO:0031667 370 0.023
heterocycle catabolic process GO:0046700 167 0.023
activation of mapkkk activity GO:0000185 1 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
calcium ion transmembrane transport GO:0070588 70 0.023
eye development GO:0001654 50 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
amine metabolic process GO:0009308 38 0.022
nucleobase containing compound catabolic process GO:0034655 152 0.022
regulation of protein localization GO:0032880 81 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
neural crest cell development GO:0014032 2 0.021
cytokinetic process GO:0032506 1 0.021
chemosensory behavior GO:0007635 2 0.021
synaptic transmission GO:0007268 235 0.021
ribonucleotide catabolic process GO:0009261 136 0.021
multicellular organism reproduction GO:0032504 233 0.021
negative regulation of phosphorus metabolic process GO:0010563 80 0.021
cellular cation homeostasis GO:0030003 180 0.021
positive regulation of synaptic vesicle transport GO:1902805 3 0.021
rhythmic process GO:0048511 156 0.020
single organism membrane organization GO:0044802 74 0.020
negative regulation of gene expression GO:0010629 199 0.020
establishment of organelle localization GO:0051656 37 0.020
regulation of neurotransmitter levels GO:0001505 42 0.020
regulation of cell migration GO:0030334 128 0.020
exocytosis GO:0006887 60 0.020
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.020
anterior posterior pattern specification GO:0009952 1 0.020
response to lipopolysaccharide GO:0032496 191 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
spindle organization GO:0007051 2 0.020
ras protein signal transduction GO:0007265 29 0.020
developmental growth GO:0048589 100 0.020
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
organophosphate catabolic process GO:0046434 148 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
neuromuscular process GO:0050905 2 0.019
maintenance of location GO:0051235 17 0.019
metal ion homeostasis GO:0055065 186 0.019
cellular homeostasis GO:0019725 252 0.019
cellular ketone metabolic process GO:0042180 51 0.019
sequestering of metal ion GO:0051238 9 0.019
olfactory learning GO:0008355 1 0.019
neurotransmitter secretion GO:0007269 33 0.019
regulation of locomotion GO:0040012 148 0.019
alternative mrna splicing via spliceosome GO:0000380 4 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
cytoskeleton organization GO:0007010 111 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
regulation of smooth muscle cell proliferation GO:0048660 75 0.018
cell cycle GO:0007049 101 0.018
sequestering of calcium ion GO:0051208 8 0.018
negative regulation of cell communication GO:0010648 158 0.018
regulation of metal ion transport GO:0010959 118 0.018
organ morphogenesis GO:0009887 75 0.018
regulation of response to stress GO:0080134 126 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
chemical homeostasis GO:0048878 292 0.018
positive regulation of protein modification process GO:0031401 142 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
calcium ion homeostasis GO:0055074 162 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
inflammatory response GO:0006954 150 0.018
glycosyl compound metabolic process GO:1901657 182 0.017
camp metabolic process GO:0046058 63 0.017
response to nutrient GO:0007584 248 0.017
immune response GO:0006955 104 0.017
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.017
central nervous system neuron axonogenesis GO:0021955 1 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
negative regulation of cell projection organization GO:0031345 50 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
regulation of protein kinase activity GO:0045859 105 0.017
peptidyl amino acid modification GO:0018193 126 0.017
small molecule biosynthetic process GO:0044283 124 0.017
negative regulation of cell development GO:0010721 82 0.017
mapk cascade GO:0000165 140 0.017
regulation of dendrite morphogenesis GO:0048814 33 0.017
transmission of nerve impulse GO:0019226 42 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
hormone secretion GO:0046879 115 0.017
developmental process involved in reproduction GO:0003006 159 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
response to cytokine GO:0034097 215 0.016
regulation of peptide hormone secretion GO:0090276 80 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
cellular protein complex assembly GO:0043623 44 0.016
cognition GO:0050890 92 0.016
nucleoside catabolic process GO:0009164 126 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
action potential GO:0001508 54 0.016
neuron death GO:0070997 127 0.016
protein import GO:0017038 37 0.016
cellular macromolecular complex assembly GO:0034622 58 0.016
cellular response to peptide GO:1901653 133 0.016
response to other organism GO:0051707 220 0.016
cell growth GO:0016049 104 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
second messenger mediated signaling GO:0019932 51 0.016
response to radiation GO:0009314 137 0.015
organelle localization GO:0051640 55 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
axis specification GO:0009798 4 0.015
regulation of synaptic plasticity GO:0048167 70 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
positive regulation of cell death GO:0010942 184 0.015
regulation of synapse maturation GO:0090128 2 0.015
protein oligomerization GO:0051259 191 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
regulation of ion transmembrane transport GO:0034765 121 0.015
regulation of transmembrane transport GO:0034762 122 0.015
response to insulin GO:0032868 133 0.015
neuronal action potential GO:0019228 35 0.015
nucleocytoplasmic transport GO:0006913 48 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
negative regulation of cell death GO:0060548 229 0.015
circulatory system process GO:0003013 183 0.015
regulation of camp biosynthetic process GO:0030817 38 0.015
insulin like growth factor receptor signaling pathway GO:0048009 3 0.015
cellular amino acid biosynthetic process GO:0008652 32 0.015
aging GO:0007568 241 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
carboxylic acid biosynthetic process GO:0046394 83 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
male gamete generation GO:0048232 99 0.014
response to oxidative stress GO:0006979 186 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
protein tetramerization GO:0051262 38 0.014
cellular response to external stimulus GO:0071496 118 0.014
gliogenesis GO:0042063 93 0.014
response to peptide hormone GO:0043434 278 0.014
calcium ion transport GO:0006816 131 0.014
regulation of axonogenesis GO:0050770 37 0.014
response to estrogen GO:0043627 232 0.014
actin filament based process GO:0030029 86 0.014
protein heterooligomerization GO:0051291 89 0.014
axon cargo transport GO:0008088 1 0.014
nucleoside triphosphate catabolic process GO:0009143 123 0.014
heart morphogenesis GO:0003007 3 0.014
circadian rhythm GO:0007623 88 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
aromatic compound catabolic process GO:0019439 168 0.014
negative regulation of neuron projection development GO:0010977 46 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
morphogenesis of a polarized epithelium GO:0001738 1 0.014
organic acid catabolic process GO:0016054 49 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
purine containing compound catabolic process GO:0072523 138 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
embryonic pattern specification GO:0009880 1 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.013
regulation of hormone levels GO:0010817 187 0.013
anion transmembrane transport GO:0098656 77 0.013
divalent inorganic cation transport GO:0072511 134 0.013
regulation of cell adhesion GO:0030155 52 0.013
defecation GO:0030421 1 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
regulation of calcium ion transport GO:0051924 77 0.013
camera type eye morphogenesis GO:0048593 2 0.013
cytoskeleton dependent cytokinesis GO:0061640 2 0.013
insulin secretion GO:0030073 69 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
positive regulation of locomotion GO:0040017 102 0.013
regulation of homeostatic process GO:0032844 101 0.013
lipid modification GO:0030258 52 0.013
negative regulation of molecular function GO:0044092 133 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
synaptic vesicle endocytosis GO:0048488 4 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
memory GO:0007613 54 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
monocarboxylic acid biosynthetic process GO:0072330 48 0.012
positive regulation of cyclase activity GO:0031281 15 0.012
organelle inheritance GO:0048308 2 0.012
neuron recognition GO:0008038 9 0.012
peptide hormone secretion GO:0030072 84 0.012
response to biotic stimulus GO:0009607 226 0.012
nucleoside metabolic process GO:0009116 179 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
regulation of establishment of planar polarity GO:0090175 2 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
establishment of tissue polarity GO:0007164 2 0.012
female pregnancy GO:0007565 122 0.012
response to monosaccharide GO:0034284 159 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
calcium mediated signaling using intracellular calcium source GO:0035584 1 0.012
neuron apoptotic process GO:0051402 88 0.012
tube development GO:0035295 89 0.012
gastrulation GO:0007369 2 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
embryo development GO:0009790 49 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
carboxylic acid catabolic process GO:0046395 49 0.012
glycerolipid metabolic process GO:0046486 67 0.012
hormone transport GO:0009914 121 0.012
heart development GO:0007507 72 0.012
single organism behavior GO:0044708 130 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
gland development GO:0048732 155 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
fatty acid metabolic process GO:0006631 99 0.011
regulation of neuronal synaptic plasticity GO:0048168 31 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
cilium morphogenesis GO:0060271 2 0.011
meiotic cell cycle process GO:1903046 3 0.011
carbohydrate metabolic process GO:0005975 130 0.011
circulatory system development GO:0072359 134 0.011
protein localization to membrane GO:0072657 36 0.011
cgmp catabolic process GO:0046069 6 0.011
rho protein signal transduction GO:0007266 11 0.011
peptide secretion GO:0002790 86 0.011
regulation of kinase activity GO:0043549 117 0.011
protein localization to nucleus GO:0034504 39 0.011
cell projection assembly GO:0030031 21 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
regulation of transporter activity GO:0032409 50 0.011
regulation of protein transport GO:0051223 68 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
multicellular organismal signaling GO:0035637 44 0.011
lipid transport GO:0006869 61 0.011
response to glucose GO:0009749 136 0.011
gtp metabolic process GO:0046039 72 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011

Spire1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
disease of cellular proliferation DOID:14566 0 0.024
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
central nervous system disease DOID:331 0 0.013
neuromuscular disease DOID:440 0 0.012
neuropathy DOID:870 0 0.012