Rattus norvegicus

0 known processes

Sprr3

small proline-rich protein 3

Sprr3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of phosphate metabolic process GO:0045937 262 0.283
positive regulation of biosynthetic process GO:0009891 319 0.176
multi multicellular organism process GO:0044706 138 0.157
regulation of molecular function GO:0065009 398 0.157
female pregnancy GO:0007565 122 0.150
positive regulation of multicellular organismal process GO:0051240 387 0.145
vascular process in circulatory system GO:0003018 96 0.145
anatomical structure morphogenesis GO:0009653 298 0.133
regulation of blood vessel size GO:0050880 89 0.126
response to nicotine GO:0035094 51 0.122
neuron development GO:0048666 286 0.117
regulation of multicellular organismal development GO:2000026 376 0.113
neuron projection development GO:0031175 273 0.111
g protein coupled receptor signaling pathway GO:0007186 242 0.111
blood circulation GO:0008015 183 0.109
single organism reproductive process GO:0044702 297 0.105
circulatory system process GO:0003013 183 0.103
regulation of system process GO:0044057 208 0.101
reproductive process GO:0022414 372 0.098
ovulation cycle process GO:0022602 50 0.097
cellular response to organic cyclic compound GO:0071407 202 0.097
chemical homeostasis GO:0048878 292 0.093
secretion by cell GO:0032940 248 0.093
response to nutrient GO:0007584 248 0.089
positive regulation of cellular biosynthetic process GO:0031328 295 0.088
circulatory system development GO:0072359 134 0.087
response to estradiol GO:0032355 164 0.083
multicellular organism reproduction GO:0032504 233 0.081
multi organism reproductive process GO:0044703 262 0.080
neuron differentiation GO:0030182 368 0.080
response to molecule of bacterial origin GO:0002237 194 0.076
single organism biosynthetic process GO:0044711 342 0.076
cellular response to steroid hormone stimulus GO:0071383 93 0.075
regulation of epithelial cell proliferation GO:0050678 49 0.075
response to nutrient levels GO:0031667 370 0.075
regulation of transcription dna templated GO:0006355 374 0.072
response to inorganic substance GO:0010035 377 0.072
catabolic process GO:0009056 351 0.072
localization of cell GO:0051674 202 0.071
positive regulation of rna biosynthetic process GO:1902680 197 0.071
cellular response to fluid shear stress GO:0071498 4 0.070
cation homeostasis GO:0055080 195 0.069
cellular response to endogenous stimulus GO:0071495 377 0.068
secretion GO:0046903 307 0.066
regeneration GO:0031099 163 0.066
positive regulation of phosphorus metabolic process GO:0010562 262 0.066
positive regulation of cell communication GO:0010647 271 0.066
apoptotic process GO:0006915 381 0.065
ovulation cycle GO:0042698 67 0.065
cell projection organization GO:0030030 302 0.065
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.064
positive regulation of cell migration GO:0030335 96 0.063
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.063
response to high light intensity GO:0009644 1 0.063
response to metal ion GO:0010038 253 0.062
regulation of nucleic acid templated transcription GO:1903506 380 0.062
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.061
positive regulation of transport GO:0051050 245 0.061
homeostatic process GO:0042592 331 0.060
ribose phosphate metabolic process GO:0019693 235 0.060
rna metabolic process GO:0016070 406 0.060
locomotion GO:0040011 237 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.060
regulation of hormone levels GO:0010817 187 0.059
reproduction GO:0000003 245 0.059
positive regulation of apoptotic process GO:0043065 154 0.058
cellular homeostasis GO:0019725 252 0.058
cellular lipid metabolic process GO:0044255 208 0.058
cellular response to iron iii ion GO:0071283 3 0.057
positive regulation of signal transduction GO:0009967 175 0.057
cardiovascular system development GO:0072358 134 0.055
proteolysis GO:0006508 175 0.054
cellular amide metabolic process GO:0043603 44 0.054
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.053
response to indole 3 methanol GO:0071680 2 0.053
response to alkaloid GO:0043279 132 0.052
regulation of neurogenesis GO:0050767 247 0.052
regulation of secretion by cell GO:1903530 208 0.052
response to lipopolysaccharide GO:0032496 191 0.052
regulation of nervous system development GO:0051960 264 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.051
regulation of anatomical structure size GO:0090066 135 0.051
cellular metal ion homeostasis GO:0006875 172 0.050
cellular divalent inorganic cation homeostasis GO:0072503 162 0.049
negative regulation of cellular metabolic process GO:0031324 281 0.048
angiogenesis GO:0001525 53 0.048
regulation of secretion GO:0051046 224 0.048
organonitrogen compound catabolic process GO:1901565 179 0.048
organophosphate biosynthetic process GO:0090407 143 0.047
response to cytokine GO:0034097 215 0.046
response to organophosphorus GO:0046683 102 0.046
response to acid chemical GO:0001101 222 0.046
organic hydroxy compound metabolic process GO:1901615 115 0.046
programmed cell death GO:0012501 392 0.046
regulation of hydrolase activity GO:0051336 143 0.045
single organism catabolic process GO:0044712 283 0.045
organonitrogen compound biosynthetic process GO:1901566 167 0.045
positive regulation of neurogenesis GO:0050769 165 0.044
rna biosynthetic process GO:0032774 380 0.044
regulation of programmed cell death GO:0043067 341 0.044
response to biotic stimulus GO:0009607 226 0.043
blood vessel development GO:0001568 69 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.042
response to corticosteroid GO:0031960 235 0.042
multicellular organismal reproductive process GO:0048609 233 0.042
macromolecular complex assembly GO:0065003 273 0.042
cellular component movement GO:0006928 248 0.042
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.041
vasculature development GO:0001944 70 0.041
rhythmic process GO:0048511 156 0.041
negative regulation of multicellular organismal process GO:0051241 203 0.041
regulation of cellular component movement GO:0051270 150 0.041
regulation of rna biosynthetic process GO:2001141 381 0.040
divalent inorganic cation homeostasis GO:0072507 165 0.040
regulation of cellular component organization GO:0051128 368 0.040
nucleic acid templated transcription GO:0097659 379 0.039
urinary bladder smooth muscle contraction GO:0014832 4 0.039
sexual reproduction GO:0019953 148 0.039
prostate gland epithelium morphogenesis GO:0060740 2 0.039
calcium ion homeostasis GO:0055074 162 0.039
macromolecular complex subunit organization GO:0043933 339 0.038
response to retinoic acid GO:0032526 63 0.037
steroid metabolic process GO:0008202 73 0.037
response to external biotic stimulus GO:0043207 221 0.037
central nervous system development GO:0007417 311 0.037
phasic smooth muscle contraction GO:0014821 3 0.037
regulation of cell proliferation GO:0042127 359 0.037
cellular catabolic process GO:0044248 295 0.037
regulation of cell migration GO:0030334 128 0.037
regulation of phosphorylation GO:0042325 248 0.036
renal system development GO:0072001 67 0.036
female gonad development GO:0008585 53 0.036
cellular component assembly GO:0022607 360 0.036
ion homeostasis GO:0050801 212 0.036
regulation of catalytic activity GO:0050790 304 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
response to monosaccharide GO:0034284 159 0.035
positive regulation of molecular function GO:0044093 230 0.035
positive regulation of epithelial cell proliferation GO:0050679 32 0.035
transcription dna templated GO:0006351 377 0.035
regulation of transferase activity GO:0051338 123 0.034
negative regulation of metabolic process GO:0009892 331 0.034
urinary tract smooth muscle contraction GO:0014848 4 0.034
cellular component biogenesis GO:0044085 368 0.034
regulation of vasculature development GO:1901342 44 0.033
organic substance catabolic process GO:1901575 316 0.033
negative regulation of cell proliferation GO:0008285 119 0.033
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
regulation of neuron differentiation GO:0045664 208 0.033
cellular chemical homeostasis GO:0055082 247 0.033
regulation of apoptotic process GO:0042981 335 0.033
positive regulation of developmental process GO:0051094 283 0.032
positive regulation of phosphorylation GO:0042327 177 0.032
regulation of cell differentiation GO:0045595 320 0.032
regulation of locomotion GO:0040012 148 0.032
cellular ion homeostasis GO:0006873 184 0.031
negative regulation of transport GO:0051051 136 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.031
response to carbohydrate GO:0009743 183 0.031
regulation of smooth muscle cell migration GO:0014910 36 0.030
response to estrogen GO:0043627 232 0.030
response to peptide GO:1901652 292 0.030
protein complex subunit organization GO:0071822 302 0.030
defense response GO:0006952 194 0.029
regulation of blood circulation GO:1903522 110 0.029
organ morphogenesis GO:0009887 75 0.029
positive regulation of signaling GO:0023056 270 0.029
regulation of cell development GO:0060284 263 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
positive regulation of nervous system development GO:0051962 178 0.029
aromatic compound catabolic process GO:0019439 168 0.029
protein complex biogenesis GO:0070271 263 0.028
organophosphate metabolic process GO:0019637 370 0.028
response to low density lipoprotein particle GO:0055098 4 0.028
response to ketone GO:1901654 182 0.028
behavior GO:0007610 205 0.027
cellular response to cytokine stimulus GO:0071345 127 0.027
neurological system process GO:0050877 219 0.027
vasoconstriction GO:0042310 54 0.027
glandular epithelial cell differentiation GO:0002067 4 0.027
positive regulation of intracellular signal transduction GO:1902533 138 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
epithelium development GO:0060429 96 0.027
intracellular signal transduction GO:0035556 314 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
positive regulation of cell development GO:0010720 176 0.026
prostate gland morphogenesis GO:0060512 2 0.026
organic cyclic compound catabolic process GO:1901361 175 0.026
purine containing compound metabolic process GO:0072521 253 0.026
regulation of cell projection organization GO:0031344 175 0.025
amine metabolic process GO:0009308 38 0.025
blood vessel morphogenesis GO:0048514 58 0.025
heart development GO:0007507 72 0.025
negative regulation of cell communication GO:0010648 158 0.025
head development GO:0060322 247 0.025
negative regulation of rna metabolic process GO:0051253 123 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
cell cell signaling GO:0007267 335 0.025
response to extracellular stimulus GO:0009991 380 0.025
hindlimb morphogenesis GO:0035137 2 0.025
ras protein signal transduction GO:0007265 29 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
regulation of saliva secretion GO:0046877 3 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
micturition GO:0060073 4 0.024
regulation of amine transport GO:0051952 54 0.024
muscle contraction GO:0006936 88 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
protein phosphorylation GO:0006468 345 0.024
saliva secretion GO:0046541 3 0.023
transformation of host cell by virus GO:0019087 4 0.023
erk1 and erk2 cascade GO:0070371 48 0.023
cellular ketone metabolic process GO:0042180 51 0.023
positive regulation of gene expression GO:0010628 244 0.023
tissue development GO:0009888 252 0.023
cell motility GO:0048870 202 0.023
negative regulation of rna biosynthetic process GO:1902679 118 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
negative regulation of gene expression GO:0010629 199 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
cell migration GO:0016477 197 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
response to vitamin GO:0033273 131 0.023
cellular amine metabolic process GO:0044106 38 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.023
metal ion homeostasis GO:0055065 186 0.023
embryonic appendage morphogenesis GO:0035113 4 0.022
regulation of cellular localization GO:0060341 263 0.022
collagen catabolic process GO:0030574 2 0.022
brain renin angiotensin system GO:0002035 3 0.022
mapk cascade GO:0000165 140 0.022
epithelial cell proliferation GO:0050673 54 0.022
signal release GO:0023061 145 0.022
cellular response to alcohol GO:0097306 87 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
cellular response to corticosteroid stimulus GO:0071384 69 0.021
monoamine transport GO:0015844 43 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
response to camp GO:0051591 91 0.021
response to glucocorticoid GO:0051384 223 0.021
negative regulation of molecular function GO:0044092 133 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
regulation of cell motility GO:2000145 131 0.021
nucleotide metabolic process GO:0009117 279 0.021
purine nucleotide biosynthetic process GO:0006164 83 0.021
brain development GO:0007420 247 0.020
potassium ion transport GO:0006813 97 0.020
nitrogen compound transport GO:0071705 229 0.020
response to growth factor GO:0070848 189 0.020
muscle tissue development GO:0060537 58 0.020
cellular nitrogen compound catabolic process GO:0044270 163 0.020
negative regulation of cell death GO:0060548 229 0.020
lipid metabolic process GO:0006629 283 0.020
positive regulation of blood circulation GO:1903524 65 0.020
hormone secretion GO:0046879 115 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
embryonic hindlimb morphogenesis GO:0035116 2 0.019
regulation of hormone secretion GO:0046883 106 0.019
angiotensin mediated drinking behavior GO:0003051 2 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
regulation of erk1 and erk2 cascade GO:0070372 41 0.019
regulation of tube size GO:0035150 89 0.019
response to glucose GO:0009749 136 0.019
cellular response to lipid GO:0071396 201 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
regulation of mapk cascade GO:0043408 116 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
forebrain development GO:0030900 98 0.018
renal system process GO:0003014 40 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
aging GO:0007568 241 0.018
cellular response to estradiol stimulus GO:0071392 16 0.018
positive regulation of synaptic plasticity GO:0031915 3 0.018
growth GO:0040007 165 0.018
lipid biosynthetic process GO:0008610 128 0.018
peptide metabolic process GO:0006518 32 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
protein oligomerization GO:0051259 191 0.018
regulation of blood pressure GO:0008217 83 0.018
regulation of protein metabolic process GO:0051246 289 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.017
regulation of systemic arterial blood pressure GO:0003073 30 0.017
alcohol metabolic process GO:0006066 77 0.017
regulation of muscle system process GO:0090257 79 0.017
appendage morphogenesis GO:0035107 4 0.017
cell growth GO:0016049 104 0.017
reproductive structure development GO:0048608 128 0.017
immune system process GO:0002376 204 0.017
cellular response to metal ion GO:0071248 55 0.017
regulation of signal transduction GO:0009966 318 0.017
protein complex assembly GO:0006461 263 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.016
positive regulation of ion transport GO:0043270 94 0.016
amino acid transport GO:0006865 70 0.016
regulation of vasoconstriction GO:0019229 44 0.016
gamete generation GO:0007276 124 0.016
striated muscle tissue development GO:0014706 58 0.016
urogenital system development GO:0001655 78 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
activation of protein kinase activity GO:0032147 47 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
organophosphate catabolic process GO:0046434 148 0.016
response to hexose GO:0009746 144 0.016
multicellular organismal catabolic process GO:0044243 2 0.016
regulation of neurological system process GO:0031644 43 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
multicellular organismal signaling GO:0035637 44 0.015
heterocycle catabolic process GO:0046700 167 0.015
response to radiation GO:0009314 137 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
response to hypoxia GO:0001666 231 0.015
regulation of cardiac muscle tissue development GO:0055024 12 0.014
regulation of lipid metabolic process GO:0019216 68 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
regulation of neuron projection development GO:0010975 161 0.014
cation transport GO:0006812 382 0.014
negative regulation of response to external stimulus GO:0032102 37 0.014
wound healing GO:0042060 122 0.014
reproductive system development GO:0061458 128 0.014
response to purine containing compound GO:0014074 126 0.014
response to temperature stimulus GO:0009266 94 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.014
ovulation GO:0030728 17 0.014
response to ethanol GO:0045471 162 0.014
palate development GO:0060021 2 0.014
vasodilation GO:0042311 44 0.014
negative regulation of developmental process GO:0051093 125 0.014
regulation of metal ion transport GO:0010959 118 0.014
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
development of primary female sexual characteristics GO:0046545 56 0.013
potassium ion transmembrane transport GO:0071805 71 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
anion transport GO:0006820 178 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
smooth muscle contraction involved in micturition GO:0060083 1 0.013
limb morphogenesis GO:0035108 4 0.013
response to activity GO:0014823 73 0.013
camera type eye development GO:0043010 48 0.013
liver development GO:0001889 90 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
muscle cell migration GO:0014812 36 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
muscle cell proliferation GO:0033002 84 0.013
protein maturation GO:0051604 68 0.013
nucleotide catabolic process GO:0009166 139 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
response to wounding GO:0009611 254 0.013
negative regulation of signaling GO:0023057 157 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
regulation of receptor activity GO:0010469 29 0.013
sensory perception of pain GO:0019233 73 0.013
camp metabolic process GO:0046058 63 0.013
embryonic limb morphogenesis GO:0030326 4 0.012
gtp metabolic process GO:0046039 72 0.012
axon development GO:0061564 96 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
positive regulation of peptide secretion GO:0002793 52 0.012
peptide catabolic process GO:0043171 5 0.012
oxoacid metabolic process GO:0043436 290 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
organ growth GO:0035265 24 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
sex differentiation GO:0007548 113 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.012
cellular response to retinoic acid GO:0071300 27 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.012
amine transport GO:0015837 57 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
nucleoside metabolic process GO:0009116 179 0.012
development of primary sexual characteristics GO:0045137 107 0.012
positive regulation of protein modification process GO:0031401 142 0.012
positive regulation of cell death GO:0010942 184 0.012
muscle organ development GO:0007517 50 0.012
negative regulation of secretion GO:0051048 82 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
eye morphogenesis GO:0048592 4 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
ethanolamine containing compound metabolic process GO:0042439 14 0.011
gonad development GO:0008406 104 0.011
negative regulation of nervous system development GO:0051961 79 0.011
regulation of protein maturation GO:1903317 50 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
smooth muscle cell migration GO:0014909 36 0.011
synaptic transmission GO:0007268 235 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
divalent inorganic cation transport GO:0072511 134 0.011
purine containing compound catabolic process GO:0072523 138 0.011
collagen metabolic process GO:0032963 21 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
regulation of lipid biosynthetic process GO:0046890 38 0.011
ossification GO:0001503 70 0.010
negative regulation of protein processing GO:0010955 47 0.010
cyclic nucleotide biosynthetic process GO:0009190 63 0.010
positive regulation of hormone secretion GO:0046887 65 0.010
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
antigen processing and presentation GO:0019882 2 0.010
sterol homeostasis GO:0055092 3 0.010
regulation of protein kinase activity GO:0045859 105 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
regulation of ras protein signal transduction GO:0046578 45 0.010
regulation of body fluid levels GO:0050878 90 0.010
organic hydroxy compound biosynthetic process GO:1901617 51 0.010
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.010
positive regulation of renal sodium excretion GO:0035815 10 0.010
positive regulation of saliva secretion GO:0046878 3 0.010

Sprr3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
disease of metabolism DOID:0014667 0 0.014
sensory system disease DOID:0050155 0 0.012