Rattus norvegicus

21 known processes

Sqle

squalene epoxidase

Sqle biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid biosynthetic process GO:0008610 128 0.966
alcohol biosynthetic process GO:0046165 38 0.925
steroid biosynthetic process GO:0006694 48 0.729
cholesterol metabolic process GO:0008203 17 0.689
cellular ketone body metabolic process GO:0046950 4 0.621
response to fatty acid GO:0070542 65 0.620
lipid metabolic process GO:0006629 283 0.615
sterol biosynthetic process GO:0016126 10 0.530
sterol metabolic process GO:0016125 18 0.526
single organism biosynthetic process GO:0044711 342 0.517
positive regulation of skeletal muscle tissue development GO:0048643 4 0.479
tissue development GO:0009888 252 0.446
cellular lipid metabolic process GO:0044255 208 0.445
regulation of cholesterol metabolic process GO:0090181 5 0.437
cellular response to peptide hormone stimulus GO:0071375 120 0.420
metanephric tubule development GO:0072170 4 0.420
isoprenoid metabolic process GO:0006720 45 0.407
response to starvation GO:0042594 59 0.390
cellular response to oxygen containing compound GO:1901701 386 0.389
small molecule biosynthetic process GO:0044283 124 0.386
cholesterol biosynthetic process GO:0006695 10 0.375
steroid metabolic process GO:0008202 73 0.361
cellular response to nitrogen compound GO:1901699 210 0.359
metanephric epithelium development GO:0072207 4 0.359
epithelium development GO:0060429 96 0.338
isoprenoid biosynthetic process GO:0008299 12 0.316
connective tissue development GO:0061448 33 0.287
response to extracellular stimulus GO:0009991 380 0.277
response to acid chemical GO:0001101 222 0.277
head development GO:0060322 247 0.240
programmed cell death GO:0012501 392 0.237
regulation of hormone levels GO:0010817 187 0.229
response to organophosphorus GO:0046683 102 0.214
cellular response to organonitrogen compound GO:0071417 197 0.199
gonad development GO:0008406 104 0.189
response to cholesterol GO:0070723 13 0.184
response to peptide GO:1901652 292 0.168
cellular response to lipid GO:0071396 201 0.168
cellular response to fatty acid GO:0071398 29 0.153
demethylation GO:0070988 7 0.152
brain development GO:0007420 247 0.152
regulation of response to wounding GO:1903034 69 0.147
positive regulation of cell death GO:0010942 184 0.141
cellular response to follicle stimulating hormone stimulus GO:0071372 13 0.139
tube development GO:0035295 89 0.132
response to ketone GO:1901654 182 0.128
response to triglyceride GO:0034014 3 0.122
response to ethanol GO:0045471 162 0.122
urogenital system development GO:0001655 78 0.111
cellular response to organic cyclic compound GO:0071407 202 0.110
response to peptide hormone GO:0043434 278 0.109
multicellular organismal response to stress GO:0033555 25 0.098
cellular response to peptide GO:1901653 133 0.097
response to nutrient GO:0007584 248 0.095
single organism reproductive process GO:0044702 297 0.094
secretion GO:0046903 307 0.092
protein complex biogenesis GO:0070271 263 0.091
reproductive system development GO:0061458 128 0.086
positive regulation of cell growth GO:0030307 44 0.084
cellular response to insulin stimulus GO:0032869 81 0.081
organic hydroxy compound biosynthetic process GO:1901617 51 0.079
response to temperature stimulus GO:0009266 94 0.077
cellular response to hormone stimulus GO:0032870 247 0.075
response to corticosteroid GO:0031960 235 0.072
regulation of multicellular organismal development GO:2000026 376 0.068
cellular response to acid chemical GO:0071229 75 0.066
response to monosaccharide GO:0034284 159 0.065
cellular chemical homeostasis GO:0055082 247 0.063
cellular response to cholesterol GO:0071397 9 0.063
organic hydroxy compound metabolic process GO:1901615 115 0.062
response to testosterone GO:0033574 55 0.061
adipose tissue development GO:0060612 6 0.060
regulation of cardiac muscle tissue development GO:0055024 12 0.060
response to sterol GO:0036314 13 0.060
response to hexose GO:0009746 144 0.056
response to biotic stimulus GO:0009607 226 0.056
regulation of muscle organ development GO:0048634 26 0.056
response to nutrient levels GO:0031667 370 0.056
macromolecular complex assembly GO:0065003 273 0.055
cellular response to alcohol GO:0097306 87 0.054
hepaticobiliary system development GO:0061008 90 0.053
negative regulation of peptide hormone secretion GO:0090278 30 0.052
organophosphate biosynthetic process GO:0090407 143 0.051
response to insulin GO:0032868 133 0.050
regulation of developmental growth GO:0048638 45 0.049
response to carbohydrate GO:0009743 183 0.049
response to metal ion GO:0010038 253 0.048
ketone body metabolic process GO:1902224 3 0.048
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.045
central nervous system development GO:0007417 311 0.044
response to inorganic substance GO:0010035 377 0.044
response to glucose GO:0009749 136 0.043
kidney development GO:0001822 67 0.043
cofactor metabolic process GO:0051186 95 0.041
metanephric nephron tubule development GO:0072234 3 0.040
protein complex subunit organization GO:0071822 302 0.040
propionate biosynthetic process GO:0019542 2 0.040
regulation of signal transduction GO:0009966 318 0.039
reproductive process GO:0022414 372 0.038
negative regulation of homeostatic process GO:0032845 47 0.038
metanephric nephron epithelium development GO:0072243 3 0.038
positive regulation of muscle organ development GO:0048636 13 0.038
developmental process involved in reproduction GO:0003006 159 0.038
cellular response to endogenous stimulus GO:0071495 377 0.037
negative regulation of multicellular organismal process GO:0051241 203 0.037
negative regulation of vasodilation GO:0045908 3 0.037
regulation of cell development GO:0060284 263 0.036
reproductive structure development GO:0048608 128 0.036
response to estrogen GO:0043627 232 0.036
positive regulation of cardiac muscle cell apoptotic process GO:0010666 3 0.036
regulation of cell differentiation GO:0045595 320 0.036
cellular component assembly GO:0022607 360 0.035
gland development GO:0048732 155 0.034
response to purine containing compound GO:0014074 126 0.034
regulation of cell growth GO:0001558 85 0.034
protein complex assembly GO:0006461 263 0.034
response to vitamin e GO:0033197 24 0.034
regulation of apoptotic process GO:0042981 335 0.034
striated muscle tissue development GO:0014706 58 0.034
cellular component biogenesis GO:0044085 368 0.034
cellular response to molecule of bacterial origin GO:0071219 56 0.033
midgut development GO:0007494 13 0.033
cell projection organization GO:0030030 302 0.033
positive regulation of cell communication GO:0010647 271 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
positive regulation of striated muscle cell apoptotic process GO:0010663 3 0.032
cell cell signaling GO:0007267 335 0.032
regulation of molecular function GO:0065009 398 0.031
regulation of cell proliferation GO:0042127 359 0.031
growth GO:0040007 165 0.030
regulation of rna biosynthetic process GO:2001141 381 0.029
coenzyme metabolic process GO:0006732 86 0.029
liver development GO:0001889 90 0.029
cellular homeostasis GO:0019725 252 0.029
regulation of cholesterol biosynthetic process GO:0045540 4 0.029
regulation of cellular localization GO:0060341 263 0.028
negative regulation of hormone secretion GO:0046888 46 0.028
response to wounding GO:0009611 254 0.028
intracellular signal transduction GO:0035556 314 0.027
positive regulation of programmed cell death GO:0043068 157 0.027
positive regulation of signaling GO:0023056 270 0.027
single organism catabolic process GO:0044712 283 0.027
acetate metabolic process GO:0006083 2 0.027
response to hypoxia GO:0001666 231 0.027
fatty acid metabolic process GO:0006631 99 0.027
apoptotic process GO:0006915 381 0.027
negative regulation of cell communication GO:0010648 158 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.026
neuron differentiation GO:0030182 368 0.026
chemical homeostasis GO:0048878 292 0.026
regulation of programmed cell death GO:0043067 341 0.026
protein oligomerization GO:0051259 191 0.025
regulation of anatomical structure size GO:0090066 135 0.025
response to amino acid GO:0043200 75 0.025
positive regulation of apoptotic process GO:0043065 154 0.025
cellular response to steroid hormone stimulus GO:0071383 93 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
positive regulation of response to stimulus GO:0048584 285 0.024
phospholipid biosynthetic process GO:0008654 29 0.024
mapk cascade GO:0000165 140 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
oxidation reduction process GO:0055114 304 0.024
sex differentiation GO:0007548 113 0.023
amide transport GO:0042886 105 0.023
positive regulation of developmental process GO:0051094 283 0.023
cellular response to stress GO:0033554 269 0.023
cellular catabolic process GO:0044248 295 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
neuron development GO:0048666 286 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
reproduction GO:0000003 245 0.022
response to lipopolysaccharide GO:0032496 191 0.022
hormone transport GO:0009914 121 0.021
negative regulation of signaling GO:0023057 157 0.021
response to estradiol GO:0032355 164 0.021
secretion by cell GO:0032940 248 0.021
metanephros development GO:0001656 14 0.021
homeostatic process GO:0042592 331 0.020
response to decreased oxygen levels GO:0036293 237 0.020
neuron projection development GO:0031175 273 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
cellular response to glucocorticoid stimulus GO:0071385 68 0.020
terpenoid biosynthetic process GO:0016114 8 0.020
positive regulation of cell proliferation GO:0008284 249 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
ras protein signal transduction GO:0007265 29 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
regulation of system process GO:0044057 208 0.019
regulation of neuron differentiation GO:0045664 208 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
response to bacterium GO:0009617 200 0.019
positive regulation of cell development GO:0010720 176 0.019
cellular ion homeostasis GO:0006873 184 0.019
response to oxygen levels GO:0070482 265 0.019
cellular response to gonadotropin stimulus GO:0071371 17 0.019
blood circulation GO:0008015 183 0.018
transcription dna templated GO:0006351 377 0.018
response to follicle stimulating hormone GO:0032354 18 0.018
regulation of cell projection organization GO:0031344 175 0.018
cellular response to external stimulus GO:0071496 118 0.018
organophosphate metabolic process GO:0019637 370 0.018
signal release GO:0023061 145 0.018
rna metabolic process GO:0016070 406 0.018
cellular amine metabolic process GO:0044106 38 0.018
cellular ketone metabolic process GO:0042180 51 0.018
cell type specific apoptotic process GO:0097285 134 0.018
response to other organism GO:0051707 220 0.018
negative regulation of developmental process GO:0051093 125 0.017
alcohol metabolic process GO:0006066 77 0.017
organic acid transport GO:0015849 116 0.017
response to stilbenoid GO:0035634 1 0.017
regulation of secretion by cell GO:1903530 208 0.017
organic substance catabolic process GO:1901575 316 0.017
cation transport GO:0006812 382 0.017
amine metabolic process GO:0009308 38 0.017
transmembrane transport GO:0055085 412 0.017
muscle cell differentiation GO:0042692 52 0.016
cation transmembrane transport GO:0098655 263 0.016
regulation of cellular component organization GO:0051128 368 0.016
cellular response to carbohydrate stimulus GO:0071322 72 0.016
positive regulation of transport GO:0051050 245 0.016
sexual reproduction GO:0019953 148 0.016
regulation of rna metabolic process GO:0051252 391 0.016
development of primary sexual characteristics GO:0045137 107 0.016
cellular response to extracellular stimulus GO:0031668 73 0.016
protein homooligomerization GO:0051260 91 0.016
catabolic process GO:0009056 351 0.016
cellular cation homeostasis GO:0030003 180 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.015
circulatory system development GO:0072359 134 0.015
response to glucocorticoid GO:0051384 223 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
metal ion transport GO:0030001 289 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
response to cytokine GO:0034097 215 0.015
proteolysis GO:0006508 175 0.015
negative regulation of cell death GO:0060548 229 0.014
carbohydrate homeostasis GO:0033500 75 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
regulation of transcription dna templated GO:0006355 374 0.014
gamete generation GO:0007276 124 0.014
neuron death GO:0070997 127 0.014
ion transmembrane transport GO:0034220 365 0.014
developmental growth GO:0048589 100 0.014
response to prostaglandin GO:0034694 16 0.014
regulation of neurogenesis GO:0050767 247 0.014
muscle cell apoptotic process GO:0010657 30 0.014
regulation of cellular response to stress GO:0080135 49 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of nervous system development GO:0051960 264 0.014
response to axon injury GO:0048678 59 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
salivary gland development GO:0007431 3 0.014
vascular process in circulatory system GO:0003018 96 0.014
response to camp GO:0051591 91 0.014
positive regulation of nervous system development GO:0051962 178 0.014
nitrogen compound transport GO:0071705 229 0.014
regulation of stress activated mapk cascade GO:0032872 23 0.014
terpenoid metabolic process GO:0006721 37 0.014
negative regulation of metabolic process GO:0009892 331 0.014
response to external biotic stimulus GO:0043207 221 0.014
response to interleukin 15 GO:0070672 4 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
heart morphogenesis GO:0003007 3 0.013
regulation of blood vessel size GO:0050880 89 0.013
cell growth GO:0016049 104 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
small molecule catabolic process GO:0044282 59 0.013
multi organism reproductive process GO:0044703 262 0.013
regeneration GO:0031099 163 0.013
synaptic vesicle endocytosis GO:0048488 4 0.013
rna biosynthetic process GO:0032774 380 0.013
organic anion transport GO:0015711 132 0.013
regulation of alcohol biosynthetic process GO:1902930 12 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
regulation of peptide transport GO:0090087 87 0.013
regulation of secretion GO:0051046 224 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.013
response to growth hormone GO:0060416 21 0.013
regulation of peptide hormone secretion GO:0090276 80 0.013
multicellular organism reproduction GO:0032504 233 0.013
digestive tract development GO:0048565 39 0.013
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.013
cytokine mediated signaling pathway GO:0019221 43 0.013
macromolecule localization GO:0033036 252 0.013
inorganic ion transmembrane transport GO:0098660 229 0.012
organelle organization GO:0006996 266 0.012
regulation of peptide secretion GO:0002791 82 0.012
male gamete generation GO:0048232 99 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
glucose homeostasis GO:0042593 75 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
nucleic acid templated transcription GO:0097659 379 0.012
ion homeostasis GO:0050801 212 0.012
mitochondrion organization GO:0007005 35 0.012
regulation of catalytic activity GO:0050790 304 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
cardiac ventricle development GO:0003231 1 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
negative regulation of molecular function GO:0044092 133 0.012
nephron epithelium development GO:0072009 14 0.012
renal system development GO:0072001 67 0.012
regulation of phosphorylation GO:0042325 248 0.012
organic acid metabolic process GO:0006082 292 0.012
hormone secretion GO:0046879 115 0.012
carboxylic acid transport GO:0046942 115 0.011
response to linoleic acid GO:0070543 3 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
muscle system process GO:0003012 115 0.011
male gonad development GO:0008584 59 0.011
dendrite development GO:0016358 72 0.011
muscle structure development GO:0061061 87 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
synaptic transmission GO:0007268 235 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
axis specification GO:0009798 4 0.011
transmission of nerve impulse GO:0019226 42 0.011
kidney epithelium development GO:0072073 19 0.011
regulation of response to stress GO:0080134 126 0.011
nephron development GO:0072006 22 0.011
wound healing GO:0042060 122 0.011
response to low light intensity stimulus GO:0009645 2 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
positive regulation of molecular function GO:0044093 230 0.011
bmp signaling pathway GO:0030509 4 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
regulation of body fluid levels GO:0050878 90 0.011
cellular response to nutrient levels GO:0031669 60 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
response to interleukin 1 GO:0070555 55 0.011
peptide secretion GO:0002790 86 0.011
embryonic pattern specification GO:0009880 1 0.010
gliogenesis GO:0042063 93 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
regulation of response to external stimulus GO:0032101 106 0.010
citrate metabolic process GO:0006101 3 0.010
adult locomotory behavior GO:0008344 4 0.010
spermatogenesis GO:0007283 99 0.010
negative regulation of catalytic activity GO:0043086 103 0.010

Sqle disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.017
disease of anatomical entity DOID:7 0 0.017
central nervous system disease DOID:331 0 0.011