Rattus norvegicus

98 known processes

Syk

spleen tyrosine kinase

(Aliases: p72syk)

Syk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cell motility GO:2000147 97 0.444
Zebrafish
cell motility GO:0048870 202 0.340
Human Zebrafish
response to oxygen levels GO:0070482 265 0.264
regulation of cell motility GO:2000145 131 0.212
Zebrafish
carboxylic acid metabolic process GO:0019752 289 0.197
Mouse
regulation of cellular component movement GO:0051270 150 0.181
Zebrafish
protein localization GO:0008104 191 0.161
Human Mouse
localization of cell GO:0051674 202 0.161
Human Zebrafish
cell migration GO:0016477 197 0.153
Human Zebrafish
positive regulation of multicellular organismal process GO:0051240 387 0.152
Zebrafish Mouse
positive regulation of isotype switching GO:0045830 1 0.135
multicellular organismal signaling GO:0035637 44 0.128
organophosphate metabolic process GO:0019637 370 0.122
nucleic acid templated transcription GO:0097659 379 0.122
Human
organic acid metabolic process GO:0006082 292 0.122
Mouse
regulation of molecular function GO:0065009 398 0.111
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 141 0.110
Zebrafish Fly
regulation of transcription dna templated GO:0006355 374 0.108
Human
locomotion GO:0040011 237 0.105
Human Zebrafish
regulation of multicellular organismal development GO:2000026 376 0.104
Zebrafish Mouse Fly
biological adhesion GO:0022610 110 0.102
Human Mouse
positive regulation of immunoglobulin production GO:0002639 4 0.101
cellular catabolic process GO:0044248 295 0.098
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.098
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.091
Mouse
ion homeostasis GO:0050801 212 0.089
cellular component movement GO:0006928 248 0.088
Human Zebrafish
catabolic process GO:0009056 351 0.087
positive regulation of cell death GO:0010942 184 0.081
immune system process GO:0002376 204 0.081
gliogenesis GO:0042063 93 0.080
behavior GO:0007610 205 0.080
regulation of phosphorus metabolic process GO:0051174 349 0.075
Mouse
response to external biotic stimulus GO:0043207 221 0.074
Mouse
homeostatic process GO:0042592 331 0.073
Mouse
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.073
rna biosynthetic process GO:0032774 380 0.073
Human
response to nutrient levels GO:0031667 370 0.072
nucleoside phosphate catabolic process GO:1901292 140 0.072
neuron differentiation GO:0030182 368 0.072
Fly
transcription dna templated GO:0006351 377 0.071
Human
central nervous system development GO:0007417 311 0.070
organic substance catabolic process GO:1901575 316 0.067
intracellular signal transduction GO:0035556 314 0.066
Mouse Fly
epithelial cell migration GO:0010631 19 0.066
Zebrafish
vesicle mediated transport GO:0016192 181 0.065
cellular component biogenesis GO:0044085 368 0.064
positive regulation of cellular protein metabolic process GO:0032270 167 0.061
Mouse
nucleobase containing small molecule metabolic process GO:0055086 316 0.061
dna metabolic process GO:0006259 96 0.061
regulation of cellular component organization GO:0051128 368 0.060
Mouse Fly
negative regulation of developmental process GO:0051093 125 0.060
response to other organism GO:0051707 220 0.060
Mouse
immune response activating signal transduction GO:0002757 15 0.059
Mouse
protein phosphorylation GO:0006468 345 0.059
positive regulation of phosphorylation GO:0042327 177 0.057
Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.057
apoptotic process GO:0006915 381 0.056
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.055
cellular carbohydrate metabolic process GO:0044262 72 0.054
rna metabolic process GO:0016070 406 0.054
Human
fc receptor mediated stimulatory signaling pathway GO:0002431 3 0.054
ribonucleoside triphosphate catabolic process GO:0009203 122 0.054
immune response regulating signaling pathway GO:0002764 19 0.054
Mouse
positive regulation of isotype switching to igg isotypes GO:0048304 1 0.053
cell activation GO:0001775 97 0.053
immunoglobulin mediated immune response GO:0016064 4 0.052
protein complex subunit organization GO:0071822 302 0.052
nucleoside metabolic process GO:0009116 179 0.051
positive regulation of rna biosynthetic process GO:1902680 197 0.050
protein autophosphorylation GO:0046777 66 0.050
regulation of neuron differentiation GO:0045664 208 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.050
organonitrogen compound catabolic process GO:1901565 179 0.050
head development GO:0060322 247 0.050
response to organophosphorus GO:0046683 102 0.049
regulation of protein phosphorylation GO:0001932 183 0.048
Mouse
organelle organization GO:0006996 266 0.047
regulation of cell migration GO:0030334 128 0.047
Zebrafish
regulation of cellular amine metabolic process GO:0033238 8 0.047
macromolecule localization GO:0033036 252 0.046
Human Mouse
ribose phosphate metabolic process GO:0019693 235 0.046
nucleotide catabolic process GO:0009166 139 0.046
purine nucleoside triphosphate catabolic process GO:0009146 122 0.046
macromolecular complex subunit organization GO:0043933 339 0.045
reproduction GO:0000003 245 0.045
Fly
regulation of neurogenesis GO:0050767 247 0.045
cellular homeostasis GO:0019725 252 0.044
regulation of locomotion GO:0040012 148 0.044
Zebrafish
b cell activation involved in immune response GO:0002312 1 0.044
regulation of fc receptor mediated stimulatory signaling pathway GO:0060368 3 0.044
purine ribonucleoside metabolic process GO:0046128 168 0.043
defense response to other organism GO:0098542 17 0.043
Mouse
cardiovascular system development GO:0072358 134 0.043
Zebrafish Mouse
regulation of isotype switching GO:0045191 1 0.043
positive regulation of cellular biosynthetic process GO:0031328 295 0.043
Mouse
positive regulation of neurogenesis GO:0050769 165 0.042
organic cyclic compound catabolic process GO:1901361 175 0.042
regulation of neuron death GO:1901214 115 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.042
neuron projection development GO:0031175 273 0.041
Fly
single organism organelle organization GO:1902589 180 0.041
positive regulation of protein modification process GO:0031401 142 0.041
Mouse
positive regulation of cell projection organization GO:0031346 111 0.041
regulation of protein metabolic process GO:0051246 289 0.041
Mouse
secretion GO:0046903 307 0.040
immune response GO:0006955 104 0.040
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.040
positive regulation of developmental process GO:0051094 283 0.039
Zebrafish Mouse
positive regulation of response to stimulus GO:0048584 285 0.039
cellular response to biotic stimulus GO:0071216 59 0.039
Mouse
positive regulation of locomotion GO:0040017 102 0.039
Zebrafish
negative regulation of cell proliferation GO:0008285 119 0.038
cellular ketone metabolic process GO:0042180 51 0.038
regulation of phosphate metabolic process GO:0019220 349 0.037
Mouse
carbohydrate derivative metabolic process GO:1901135 346 0.037
single organism cellular localization GO:1902580 102 0.037
neuron development GO:0048666 286 0.037
Fly
divalent inorganic cation homeostasis GO:0072507 165 0.036
single organism catabolic process GO:0044712 283 0.036
cellular response to oxygen containing compound GO:1901701 386 0.036
transmission of nerve impulse GO:0019226 42 0.036
response to biotic stimulus GO:0009607 226 0.036
Mouse
response to inorganic substance GO:0010035 377 0.035
positive regulation of fc receptor mediated stimulatory signaling pathway GO:0060369 1 0.035
regulation of intracellular signal transduction GO:1902531 218 0.035
Mouse
positive regulation of programmed cell death GO:0043068 157 0.035
muscle system process GO:0003012 115 0.035
programmed cell death GO:0012501 392 0.035
positive regulation of signaling GO:0023056 270 0.035
Mouse
phagocytosis GO:0006909 17 0.035
Mouse Fly
amine metabolic process GO:0009308 38 0.035
neurological system process GO:0050877 219 0.034
multicellular organism reproduction GO:0032504 233 0.034
Fly
glial cell differentiation GO:0010001 65 0.034
organophosphate biosynthetic process GO:0090407 143 0.034
interleukin 12 production GO:0032615 3 0.034
regulation of immunoglobulin production GO:0002637 4 0.034
positive regulation of cellular component organization GO:0051130 200 0.033
regulation of nervous system development GO:0051960 264 0.033
neuron apoptotic process GO:0051402 88 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.033
Human
neuron death GO:0070997 127 0.033
regulation of cell development GO:0060284 263 0.033
cellular amine metabolic process GO:0044106 38 0.032
transmembrane transport GO:0055085 412 0.032
endocytosis GO:0006897 84 0.032
Mouse Fly
regulation of cytoskeleton organization GO:0051493 49 0.032
negative regulation of metabolic process GO:0009892 331 0.032
positive regulation of cell development GO:0010720 176 0.032
heterocycle catabolic process GO:0046700 167 0.032
reactive oxygen species metabolic process GO:0072593 37 0.032
Mouse
histamine secretion involved in inflammatory response GO:0002441 3 0.032
cell adhesion GO:0007155 110 0.032
Human Mouse
response to mechanical stimulus GO:0009612 134 0.031
long term memory GO:0007616 15 0.031
nucleotide metabolic process GO:0009117 279 0.031
neurotrophin trk receptor signaling pathway GO:0048011 10 0.031
activation of immune response GO:0002253 26 0.031
Mouse
sexual reproduction GO:0019953 148 0.031
Fly
response to decreased oxygen levels GO:0036293 237 0.031
olfactory behavior GO:0042048 2 0.031
regulation of neuron apoptotic process GO:0043523 83 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
positive regulation of platelet derived growth factor receptor signaling pathway GO:0010641 1 0.030
regulation of immune system process GO:0002682 123 0.030
single organism carbohydrate metabolic process GO:0044723 118 0.030
glycosyl compound catabolic process GO:1901658 126 0.030
response to toxic substance GO:0009636 133 0.030
atp catabolic process GO:0006200 54 0.030
regulation of mapk cascade GO:0043408 116 0.030
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
Mouse
nitrogen compound transport GO:0071705 229 0.030
Mouse
cytoskeleton organization GO:0007010 111 0.030
organ morphogenesis GO:0009887 75 0.030
multicellular organismal reproductive process GO:0048609 233 0.029
Fly
learning or memory GO:0007611 90 0.029
synaptic growth at neuromuscular junction GO:0051124 1 0.029
response to extracellular stimulus GO:0009991 380 0.029
leukocyte cell cell adhesion GO:0007159 4 0.029
Human
regulation of signal transduction GO:0009966 318 0.028
Mouse
anatomical structure morphogenesis GO:0009653 298 0.028
Zebrafish Mouse Fly
purine nucleotide catabolic process GO:0006195 136 0.028
regulation of phagocytosis GO:0050764 13 0.028
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.028
regulation of rna metabolic process GO:0051252 391 0.028
Human
mapk cascade GO:0000165 140 0.028
Mouse Fly
positive regulation of rna metabolic process GO:0051254 203 0.028
anatomical structure formation involved in morphogenesis GO:0048646 83 0.027
Zebrafish Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.027
aging GO:0007568 241 0.027
defense response to gram positive bacterium GO:0050830 2 0.027
purine containing compound metabolic process GO:0072521 253 0.027
cellular calcium ion homeostasis GO:0006874 160 0.027
cell cell junction organization GO:0045216 20 0.027
carbohydrate metabolic process GO:0005975 130 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
negative regulation of cell differentiation GO:0045596 99 0.027
growth GO:0040007 165 0.027
Fly
reproductive process GO:0022414 372 0.027
Fly
salivary gland development GO:0007431 3 0.027
establishment of protein localization GO:0045184 141 0.026
Human Mouse
single organism cell adhesion GO:0098602 46 0.026
Human Mouse
response to bacterium GO:0009617 200 0.026
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.026
regulation of immune response GO:0050776 55 0.026
defense response GO:0006952 194 0.026
Mouse
positive regulation of endothelial cell migration GO:0010595 4 0.026
Zebrafish
response to growth factor GO:0070848 189 0.026
nucleoside catabolic process GO:0009164 126 0.026
actin filament bundle assembly GO:0051017 19 0.026
multi organism reproductive process GO:0044703 262 0.026
Fly
positive regulation of signal transduction GO:0009967 175 0.026
Mouse
cellular protein localization GO:0034613 122 0.026
Human
macromolecular complex assembly GO:0065003 273 0.026
positive regulation of protein kinase activity GO:0045860 73 0.026
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.026
Human
histamine production involved in inflammatory response GO:0002349 3 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
organic acid transport GO:0015849 116 0.025
Mouse
smooth muscle cell migration GO:0014909 36 0.025
metal ion homeostasis GO:0055065 186 0.024
negative regulation of bone resorption GO:0045779 5 0.024
oxoacid metabolic process GO:0043436 290 0.024
Mouse
protein transport GO:0015031 132 0.024
Human Mouse
membrane organization GO:0061024 94 0.024
lipid metabolic process GO:0006629 283 0.024
Mouse
regulation of dna metabolic process GO:0051052 60 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
Mouse
response to carbohydrate GO:0009743 183 0.024
tissue regeneration GO:0042246 36 0.023
muscle cell migration GO:0014812 36 0.023
response to wounding GO:0009611 254 0.023
Mouse
olfactory learning GO:0008355 1 0.023
regulation of cell cycle GO:0051726 73 0.023
cellular chemical homeostasis GO:0055082 247 0.023
regulation of endocytosis GO:0030100 42 0.023
Mouse
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.023
reactive oxygen species biosynthetic process GO:1903409 8 0.023
cell projection morphogenesis GO:0048858 123 0.022
Fly
ribonucleoside triphosphate metabolic process GO:0009199 141 0.022
gland development GO:0048732 155 0.022
regulation of membrane potential GO:0042391 110 0.022
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.022
cellular modified amino acid metabolic process GO:0006575 61 0.022
positive regulation of nervous system development GO:0051962 178 0.022
leukocyte activation GO:0045321 76 0.022
regulation of protein serine threonine kinase activity GO:0071900 64 0.022
Mouse
ribonucleoside metabolic process GO:0009119 174 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
cation transport GO:0006812 382 0.022
Mouse
positive regulation of cell communication GO:0010647 271 0.022
Mouse
positive regulation of apoptotic process GO:0043065 154 0.021
cytokine biosynthetic process GO:0042089 3 0.021
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 6 0.021
Mouse
response to acid chemical GO:0001101 222 0.021
negative regulation of cellular component organization GO:0051129 83 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
Mouse
negative regulation of multicellular organismal process GO:0051241 203 0.021
reactive nitrogen species metabolic process GO:2001057 1 0.021
purine nucleoside metabolic process GO:0042278 169 0.021
positive regulation of gene expression GO:0010628 244 0.021
cellular nitrogen compound catabolic process GO:0044270 163 0.021
positive regulation of cell migration GO:0030335 96 0.021
Zebrafish
regulation of system process GO:0044057 208 0.021
negative regulation of cell matrix adhesion GO:0001953 3 0.021
purine containing compound catabolic process GO:0072523 138 0.021
positive regulation of molecular function GO:0044093 230 0.021
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.020
regulation of anatomical structure size GO:0090066 135 0.020
regulation of carbohydrate metabolic process GO:0006109 41 0.020
regulation of isotype switching to igg isotypes GO:0048302 1 0.020
organophosphate catabolic process GO:0046434 148 0.020
cellular response to lipid GO:0071396 201 0.020
positive regulation of smooth muscle cell migration GO:0014911 27 0.020
small molecule catabolic process GO:0044282 59 0.020
activation of protein kinase b activity GO:0032148 3 0.020
regulation of protein localization GO:0032880 81 0.020
Mouse
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.019
Mouse
somatic diversification of immunoglobulins involved in immune response GO:0002208 1 0.019
cellular response to extracellular stimulus GO:0031668 73 0.019
gamete generation GO:0007276 124 0.019
Fly
peptidyl serine modification GO:0018209 34 0.019
Mouse
ribonucleotide catabolic process GO:0009261 136 0.019
single organismal cell cell adhesion GO:0016337 42 0.019
Human Mouse
purine nucleoside catabolic process GO:0006152 124 0.019
isotype switching to igg isotypes GO:0048291 1 0.019
lipid catabolic process GO:0016042 46 0.018
response to purine containing compound GO:0014074 126 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
Mouse
lymphocyte activation GO:0046649 43 0.018
Mouse
positive regulation of dna recombination GO:0045911 1 0.018
circulatory system development GO:0072359 134 0.018
Zebrafish Mouse
cognition GO:0050890 92 0.018
cellular component assembly GO:0022607 360 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
histamine secretion by mast cell GO:0002553 3 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
cellular response to stress GO:0033554 269 0.018
Mouse Fly
regulation of angiogenesis GO:0045765 39 0.018
Zebrafish
signal transduction by phosphorylation GO:0023014 144 0.017
Mouse Fly
regulation of growth GO:0040008 105 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
blood circulation GO:0008015 183 0.017
single organism biosynthetic process GO:0044711 342 0.017
Mouse
response to camp GO:0051591 91 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
inositol trisphosphate metabolic process GO:0032957 4 0.017
peptidyl amino acid modification GO:0018193 126 0.017
Human Mouse
cellular response to growth factor stimulus GO:0071363 162 0.017
negative regulation of cell development GO:0010721 82 0.016
cellular amide metabolic process GO:0043603 44 0.016
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
regulation of vasculature development GO:1901342 44 0.016
Zebrafish
antigen receptor mediated signaling pathway GO:0050851 1 0.016
Mouse
cell part morphogenesis GO:0032990 123 0.016
Fly
regulation of cell proliferation GO:0042127 359 0.016
Mouse
positive regulation of neuron projection development GO:0010976 99 0.016
single organism reproductive process GO:0044702 297 0.016
Fly
chemosensory behavior GO:0007635 2 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
amine transport GO:0015837 57 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
mitotic spindle organization GO:0007052 2 0.016
signal release GO:0023061 145 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
Mouse
mononuclear cell proliferation GO:0032943 29 0.016
Mouse
regulation of body fluid levels GO:0050878 90 0.016
Mouse
ribonucleoside catabolic process GO:0042454 126 0.015
positive regulation of transcription factor import into nucleus GO:0042993 4 0.015
cellular lipid metabolic process GO:0044255 208 0.015
Mouse
single organism intracellular transport GO:1902582 166 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
neuron projection morphogenesis GO:0048812 122 0.015
Fly
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.015
cell junction organization GO:0034330 21 0.015
proteolysis GO:0006508 175 0.015
negative regulation of long term synaptic potentiation GO:1900272 1 0.015
mast cell degranulation GO:0043303 10 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.015
intracellular receptor signaling pathway GO:0030522 35 0.015
regulation of catalytic activity GO:0050790 304 0.015
Mouse
mesoderm development GO:0007498 2 0.015
developmental growth GO:0048589 100 0.015
Fly
dephosphorylation GO:0016311 98 0.015
cation homeostasis GO:0055080 195 0.015
response to cytokine GO:0034097 215 0.015
ras protein signal transduction GO:0007265 29 0.015
aromatic compound catabolic process GO:0019439 168 0.015
negative regulation of neuron death GO:1901215 69 0.015
regulation of cell differentiation GO:0045595 320 0.015
Mouse
cellular response to nitrogen compound GO:1901699 210 0.015
sequestering of metal ion GO:0051238 9 0.014
b cell mediated immunity GO:0019724 4 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
wound healing GO:0042060 122 0.014
Mouse
chemical homeostasis GO:0048878 292 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
negative regulation of growth GO:0045926 37 0.014
regulation of vesicle mediated transport GO:0060627 81 0.014
metanephric epithelium development GO:0072207 4 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
positive regulation of transport GO:0051050 245 0.014
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 1 0.014
regulation of programmed cell death GO:0043067 341 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
oligodendrocyte differentiation GO:0048709 32 0.014
spindle organization GO:0007051 2 0.014
regulation of organelle organization GO:0033043 80 0.014
positive regulation of phagocytosis engulfment GO:0060100 4 0.014
axis specification GO:0009798 4 0.014
protein complex biogenesis GO:0070271 263 0.014
regulation of protein kinase activity GO:0045859 105 0.014
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.014
platelet aggregation GO:0070527 4 0.014
Mouse
small molecule biosynthetic process GO:0044283 124 0.014
Mouse
negative regulation of adherens junction organization GO:1903392 2 0.014
cellular response to molecule of bacterial origin GO:0071219 56 0.014
regulation of t cell differentiation GO:0045580 7 0.013
Mouse
positive regulation of gtpase activity GO:0043547 47 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.013
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
regulation of protein modification process GO:0031399 194 0.013
Mouse
negative regulation of biosynthetic process GO:0009890 168 0.013
cytoplasmic transport GO:0016482 115 0.013
Human
regulation of secretion GO:0051046 224 0.013
positive regulation of immune system process GO:0002684 90 0.013
positive regulation of angiogenesis GO:0045766 28 0.013
Zebrafish
muscle contraction GO:0006936 88 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
regulation of phosphorylation GO:0042325 248 0.013
Mouse
regulation of catabolic process GO:0009894 113 0.013
regulation of hormone levels GO:0010817 187 0.013
hormone secretion GO:0046879 115 0.013
cellular cation homeostasis GO:0030003 180 0.013
embryonic pattern specification GO:0009880 1 0.013
regulation of b cell differentiation GO:0045577 1 0.013
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
action potential GO:0001508 54 0.013
positive regulation of dna metabolic process GO:0051054 39 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
glial cell development GO:0021782 19 0.013
lymphocyte activation involved in immune response GO:0002285 3 0.013
cell projection organization GO:0030030 302 0.013
Fly
response to metal ion GO:0010038 253 0.013
secretion by cell GO:0032940 248 0.013
somatic recombination of immunoglobulin gene segments GO:0016447 1 0.013
vasculature development GO:0001944 70 0.013
Zebrafish Mouse
response to fatty acid GO:0070542 65 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
Zebrafish
blood vessel morphogenesis GO:0048514 58 0.013
Zebrafish Mouse
cellular response to external stimulus GO:0071496 118 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
protein complex assembly GO:0006461 263 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
carbohydrate biosynthetic process GO:0016051 42 0.012
developmental process involved in reproduction GO:0003006 159 0.012
Fly
cell cell signaling GO:0007267 335 0.012
somatic cell dna recombination GO:0016444 2 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
neuronal action potential GO:0019228 35 0.012
metal ion transport GO:0030001 289 0.012
angiotensin maturation GO:0002003 2 0.012
regulation of cellular component size GO:0032535 51 0.012
glucose metabolic process GO:0006006 52 0.012
leukocyte aggregation GO:0070486 1 0.012
actin cytoskeleton organization GO:0030036 73 0.012
cell junction assembly GO:0034329 18 0.012
lymphocyte proliferation GO:0046651 29 0.012
Mouse
negative regulation of phosphate metabolic process GO:0045936 80 0.012
positive regulation of b cell mediated immunity GO:0002714 2 0.012
brain development GO:0007420 247 0.012
synaptic transmission GO:0007268 235 0.012
response to molecule of fungal origin GO:0002238 3 0.012
Mouse
axon ensheathment GO:0008366 40 0.012
negative regulation of neuron apoptotic process GO:0043524 45 0.012
memory GO:0007613 54 0.012
regulation of blood vessel endothelial cell migration GO:0043535 4 0.012
Zebrafish
regulation of phagocytosis engulfment GO:0060099 4 0.012
regulation of neural precursor cell proliferation GO:2000177 16 0.012
positive regulation of lipid kinase activity GO:0090218 2 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.012
regulation of cellular localization GO:0060341 263 0.012
regulation of lymphocyte activation GO:0051249 34 0.011
Mouse
single organism membrane organization GO:0044802 74 0.011
salivary gland morphogenesis GO:0007435 1 0.011
somatic diversification of immune receptors GO:0002200 2 0.011
negative regulation of secretion GO:0051048 82 0.011
regulation of ras protein signal transduction GO:0046578 45 0.011
leukocyte activation involved in immune response GO:0002366 16 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
negative regulation of signal transduction in absence of ligand GO:1901099 3 0.011
regulation of immunoglobulin secretion GO:0051023 1 0.011
embryonic axis specification GO:0000578 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
Mouse
response to zinc ion GO:0010043 39 0.011
regulation of odontogenesis of dentin containing tooth GO:0042487 2 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
intracellular transport GO:0046907 185 0.011
regulation of interleukin 12 production GO:0032655 3 0.011
progesterone receptor signaling pathway GO:0050847 1 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
cell growth GO:0016049 104 0.011
Fly
positive regulation of cellular catabolic process GO:0031331 71 0.011
ensheathment of neurons GO:0007272 40 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.011
negative regulation of chronic inflammatory response to non antigenic stimulus GO:0002881 1 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
Fly
nucleoside triphosphate catabolic process GO:0009143 123 0.011
response to transition metal nanoparticle GO:1990267 122 0.010
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 3 0.010
developmental maturation GO:0021700 25 0.010
cell junction maintenance GO:0034331 1 0.010
response to hydrogen peroxide GO:0042542 89 0.010
cellular ion homeostasis GO:0006873 184 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
blood vessel development GO:0001568 69 0.010
Zebrafish Mouse
actin filament organization GO:0007015 42 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
regulation of cytokine biosynthetic process GO:0042035 3 0.010
Mouse

Syk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
gastrointestinal system disease DOID:77 0 0.010
disease of anatomical entity DOID:7 0 0.010