|
|
wound healing
|
GO:0042060 |
122 |
0.662
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.650
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.616
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.581
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.527
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.494
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.483
|
|
|
|
muscle contraction
|
GO:0006936 |
88 |
0.427
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.426
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.411
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.385
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.382
|
Rat |
|
|
metal ion transport
|
GO:0030001 |
289 |
0.367
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.348
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.347
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
8 |
0.341
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.330
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.322
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.315
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.309
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.306
|
|
|
|
regulation of saliva secretion
|
GO:0046877 |
3 |
0.291
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.286
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.273
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.260
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.250
|
|
|
|
positive regulation of long term synaptic potentiation
|
GO:1900273 |
4 |
0.250
|
|
|
|
positive regulation of saliva secretion
|
GO:0046878 |
3 |
0.250
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.246
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.232
|
|
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.230
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.228
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.219
|
|
|
|
response to estrogen
|
GO:0043627 |
232 |
0.218
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.216
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.211
|
Rat |
|
|
immune system process
|
GO:0002376 |
204 |
0.209
|
|
|
|
tonic smooth muscle contraction
|
GO:0014820 |
4 |
0.207
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
30 |
0.206
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.203
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.202
|
Yeast |
|
|
positive regulation of cell migration
|
GO:0030335 |
96 |
0.202
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.200
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.196
|
Rat |
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.196
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.195
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.194
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.193
|
|
|
|
heart development
|
GO:0007507 |
72 |
0.193
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.189
|
|
|
|
sodium ion transport
|
GO:0006814 |
82 |
0.187
|
|
|
|
saliva secretion
|
GO:0046541 |
3 |
0.185
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.182
|
Yeast Rat |
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.177
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
24 |
0.166
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.162
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.162
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.162
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.162
|
Rat |
|
|
gland development
|
GO:0048732 |
155 |
0.162
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.161
|
Rat |
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.161
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.160
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.159
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.158
|
|
|
|
heart process
|
GO:0003015 |
57 |
0.158
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.158
|
Rat |
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.158
|
|
|
|
phasic smooth muscle contraction
|
GO:0014821 |
3 |
0.157
|
|
|
|
circulatory system process
|
GO:0003013 |
183 |
0.155
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.153
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.152
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.152
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.152
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.151
|
|
|
|
regulation of cell activation
|
GO:0050865 |
50 |
0.150
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.146
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.146
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.146
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.145
|
|
|
|
muscle tissue development
|
GO:0060537 |
58 |
0.143
|
|
|
|
leukocyte activation
|
GO:0045321 |
76 |
0.140
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.140
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
97 |
0.139
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.139
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.134
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.134
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.133
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.132
|
Rat |
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.131
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.131
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.130
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.129
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.129
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.129
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.129
|
|
|
|
regulation of the force of heart contraction by chemical signal
|
GO:0003057 |
2 |
0.129
|
|
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.129
|
|
|
|
response to nutrient
|
GO:0007584 |
248 |
0.128
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
58 |
0.126
|
|
|
|
response to ethanol
|
GO:0045471 |
162 |
0.126
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.124
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.124
|
|
|
|
response to dexamethasone
|
GO:0071548 |
49 |
0.123
|
|
|
|
muscle structure development
|
GO:0061061 |
87 |
0.122
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.122
|
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.121
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.121
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
50 |
0.121
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
96 |
0.120
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
162 |
0.118
|
|
|
|
positive regulation of the force of heart contraction by norepinephrine
|
GO:0003061 |
1 |
0.118
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.116
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.115
|
|
|
|
lymphocyte activation
|
GO:0046649 |
43 |
0.115
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.114
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.114
|
Mouse Rat |
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.114
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
4 |
0.114
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.114
|
Mouse |
|
|
negative regulation of uterine smooth muscle contraction
|
GO:0070473 |
2 |
0.113
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.113
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
106 |
0.113
|
Rat |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.111
|
|
|
|
urinary bladder smooth muscle contraction
|
GO:0014832 |
4 |
0.111
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
23 |
0.110
|
|
|
|
negative regulation of smooth muscle contraction
|
GO:0045986 |
7 |
0.110
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
29 |
0.109
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.108
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.106
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.106
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
12 |
0.105
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.105
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.104
|
Yeast |
|
|
regulation of actin filament based process
|
GO:0032970 |
42 |
0.104
|
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
2 |
0.102
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.100
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.100
|
Rat |
|
|
regulation of cell adhesion
|
GO:0030155 |
52 |
0.100
|
|
|
|
behavioral response to cocaine
|
GO:0048148 |
6 |
0.099
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.098
|
Mouse Rat |
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.098
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
45 |
0.098
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.097
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
83 |
0.097
|
|
|
|
positive regulation of renin secretion into blood stream
|
GO:1900135 |
1 |
0.097
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.096
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.096
|
Yeast |
|
|
smooth muscle contraction
|
GO:0006939 |
37 |
0.096
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
27 |
0.096
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.095
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
90 |
0.095
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.093
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.092
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.092
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
49 |
0.092
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.092
|
|
|
|
cardiac muscle tissue growth
|
GO:0055017 |
20 |
0.091
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.091
|
|
|
|
positive regulation of the force of heart contraction by epinephrine
|
GO:0003059 |
1 |
0.090
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.090
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.090
|
Yeast |
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.089
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
27 |
0.089
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
14 |
0.089
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.089
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
102 |
0.089
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
46 |
0.088
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.087
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.087
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
37 |
0.086
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.086
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.086
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.085
|
Rat |
|
|
urinary tract smooth muscle contraction
|
GO:0014848 |
4 |
0.085
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.085
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.085
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.084
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
121 |
0.084
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
80 |
0.083
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.083
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
80 |
0.082
|
Rat |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.082
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.082
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
1 |
0.082
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
10 |
0.079
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.079
|
|
|
|
response to monosaccharide
|
GO:0034284 |
159 |
0.078
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.078
|
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
29 |
0.078
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.078
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.077
|
|
|
|
growth
|
GO:0040007 |
165 |
0.076
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.076
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.076
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.076
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
102 |
0.075
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.075
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.075
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.074
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.074
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
30 |
0.074
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.073
|
|
|
|
regulation of ossification
|
GO:0030278 |
32 |
0.073
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
25 |
0.073
|
|
|
|
vasoconstriction
|
GO:0042310 |
54 |
0.072
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
83 |
0.072
|
|
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
1 |
0.071
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
45 |
0.070
|
|
|
|
cell activation
|
GO:0001775 |
97 |
0.070
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.069
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
9 |
0.068
|
|
|
|
neurological system process
|
GO:0050877 |
219 |
0.068
|
|
|
|
regulation of organ growth
|
GO:0046620 |
13 |
0.067
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.066
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.066
|
Rat |
|
|
heart contraction
|
GO:0060047 |
57 |
0.066
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.066
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
49 |
0.066
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.066
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.066
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
69 |
0.065
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.065
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.065
|
Rat |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
49 |
0.065
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.065
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.064
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.064
|
|
|
|
response to hexose
|
GO:0009746 |
144 |
0.064
|
|
|
|
striated muscle contraction
|
GO:0006941 |
44 |
0.064
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.064
|
Rat |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.063
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.063
|
|
|
|
regeneration
|
GO:0031099 |
163 |
0.063
|
|
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.062
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.061
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.061
|
|
|
|
regulation of systemic arterial blood pressure by norepinephrine epinephrine
|
GO:0001993 |
2 |
0.061
|
|
|
|
cellular component movement
|
GO:0006928 |
248 |
0.061
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
77 |
0.061
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.060
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
128 |
0.060
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.060
|
Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.060
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.059
|
|
|
|
regulation of skeletal muscle tissue growth
|
GO:0048631 |
3 |
0.059
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.059
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.058
|
|
|
|
sensory perception of pain
|
GO:0019233 |
73 |
0.058
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
32 |
0.058
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
123 |
0.057
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.057
|
Rat |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.057
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.057
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.057
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
34 |
0.057
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.057
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.057
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.057
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.056
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.056
|
|
|
|
angiogenesis
|
GO:0001525 |
53 |
0.056
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.056
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.056
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.056
|
|
|
|
positive regulation of heart contraction
|
GO:0045823 |
15 |
0.056
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.056
|
|
|
|
blood vessel development
|
GO:0001568 |
69 |
0.056
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
51 |
0.056
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
90 |
0.055
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
27 |
0.055
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.055
|
|
|
|
artery smooth muscle contraction
|
GO:0014824 |
4 |
0.055
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.055
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
41 |
0.055
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
63 |
0.055
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.055
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.055
|
|
|
|
response to organophosphorus
|
GO:0046683 |
102 |
0.054
|
|
|
|
cell cycle
|
GO:0007049 |
101 |
0.054
|
|
|
|
response to glucose
|
GO:0009749 |
136 |
0.054
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
48 |
0.054
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
42 |
0.053
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
77 |
0.053
|
|
|
|
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure
|
GO:0001999 |
1 |
0.053
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
167 |
0.053
|
|
|
|
cardiac chamber development
|
GO:0003205 |
1 |
0.053
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.053
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.053
|
|
|
|
sensory perception
|
GO:0007600 |
101 |
0.052
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.052
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
67 |
0.051
|
Yeast |
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.051
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.051
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
19 |
0.051
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
2 |
0.051
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
84 |
0.051
|
Rat |
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.051
|
|
|
|
maintenance of location
|
GO:0051235 |
17 |
0.050
|
|
|
|
regulation of tube size
|
GO:0035150 |
89 |
0.050
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.050
|
|
|
|
renin secretion into blood stream
|
GO:0002001 |
1 |
0.050
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
89 |
0.050
|
|
|
|
regulation of inhibitory postsynaptic membrane potential
|
GO:0060080 |
6 |
0.049
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.049
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
127 |
0.049
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.049
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
21 |
0.049
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
38 |
0.049
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.049
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
37 |
0.048
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.048
|
|
|
|
amide transport
|
GO:0042886 |
105 |
0.048
|
Rat |
|
|
potassium ion transport
|
GO:0006813 |
97 |
0.048
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.048
|
|
|
|
female pregnancy
|
GO:0007565 |
122 |
0.047
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
85 |
0.047
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
106 |
0.047
|
|
|
|
response to bacterium
|
GO:0009617 |
200 |
0.047
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
87 |
0.047
|
Rat |
|
|
regulation of renin secretion into blood stream
|
GO:1900133 |
1 |
0.047
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
54 |
0.047
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.046
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.046
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
26 |
0.046
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
79 |
0.046
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
62 |
0.045
|
|
|
|
cell migration
|
GO:0016477 |
197 |
0.045
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.045
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
8 |
0.045
|
|
|
|
detection of stimulus
|
GO:0051606 |
24 |
0.045
|
Rat |
|
|
glucose homeostasis
|
GO:0042593 |
75 |
0.045
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.045
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.045
|
|
|
|
organic acid transport
|
GO:0015849 |
116 |
0.045
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.044
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
17 |
0.044
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.044
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
18 |
0.044
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.044
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.043
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.043
|
|
|
|
n methyl d aspartate receptor clustering
|
GO:0097114 |
2 |
0.043
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.043
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
126 |
0.043
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.042
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
11 |
0.042
|
|
|
|
diaphragm contraction
|
GO:0002086 |
2 |
0.042
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.042
|
Rat |
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.042
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.042
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
71 |
0.042
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.041
|
|
|
|
peristalsis
|
GO:0030432 |
2 |
0.041
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.041
|
|
|
|
actin filament based movement
|
GO:0030048 |
16 |
0.041
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.041
|
|
|
|
involuntary skeletal muscle contraction
|
GO:0003011 |
2 |
0.040
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.040
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
98 |
0.040
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.040
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
50 |
0.040
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.040
|
|
|
|
response to cocaine
|
GO:0042220 |
39 |
0.040
|
|
|
|
negative regulation of chronic inflammatory response
|
GO:0002677 |
2 |
0.040
|
|
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
2 |
0.039
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
51 |
0.039
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.039
|
|
|
|
aging
|
GO:0007568 |
241 |
0.039
|
|
|
|
inflammatory response
|
GO:0006954 |
150 |
0.039
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.039
|
Rat |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.038
|
|
|
|
negative regulation of synaptic transmission gabaergic
|
GO:0032229 |
6 |
0.038
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
58 |
0.038
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.038
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.038
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
26 |
0.038
|
|
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.038
|
|
|
|
secretion by tissue
|
GO:0032941 |
37 |
0.038
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
22 |
0.037
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.037
|
|
|
|
heart growth
|
GO:0060419 |
20 |
0.037
|
|
|
|
multicellular organism growth
|
GO:0035264 |
1 |
0.037
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
48 |
0.037
|
|
|
|
negative regulation of luteinizing hormone secretion
|
GO:0033685 |
4 |
0.037
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.037
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
4 |
0.037
|
|
|
|
regulation of systemic arterial blood pressure mediated by a chemical signal
|
GO:0003044 |
13 |
0.037
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.037
|
|
|
|
positive regulation of digestive system process
|
GO:0060456 |
8 |
0.036
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.036
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
68 |
0.036
|
Yeast |
|
|
protein processing
|
GO:0016485 |
68 |
0.036
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.036
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.036
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.036
|
|
|
|
head development
|
GO:0060322 |
247 |
0.036
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
84 |
0.036
|
|
|
|
regulation of heart growth
|
GO:0060420 |
12 |
0.036
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
63 |
0.036
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.035
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
81 |
0.035
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
15 |
0.035
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.035
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.035
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.035
|
|
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.035
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
65 |
0.035
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.035
|
|
|
|
protein maturation
|
GO:0051604 |
68 |
0.035
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
23 |
0.035
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.035
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.034
|
|
|
|
regulation of organ formation
|
GO:0003156 |
2 |
0.034
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.034
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
28 |
0.034
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
44 |
0.034
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.034
|
Rat |
|
|
regulation of neurological system process
|
GO:0031644 |
43 |
0.034
|
|
|
|
regulation of protein transport
|
GO:0051223 |
68 |
0.034
|
|
|
|
positive regulation of the force of heart contraction by chemical signal
|
GO:0003099 |
2 |
0.034
|
|
|
|
organic anion transport
|
GO:0015711 |
132 |
0.033
|
|
|
|
memory
|
GO:0007613 |
54 |
0.033
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
26 |
0.033
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.033
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
110 |
0.033
|
|
|
|
brain renin angiotensin system
|
GO:0002035 |
3 |
0.033
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
16 |
0.033
|
|
|
|
acute inflammatory response
|
GO:0002526 |
58 |
0.033
|
|
|
|
neurological system process involved in regulation of systemic arterial blood pressure
|
GO:0001976 |
3 |
0.032
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
48 |
0.032
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
50 |
0.032
|
|
|
|
camp metabolic process
|
GO:0046058 |
63 |
0.032
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
93 |
0.032
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.032
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.032
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
23 |
0.032
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
94 |
0.032
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.032
|
|
|
|
sex differentiation
|
GO:0007548 |
113 |
0.031
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
65 |
0.031
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.031
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.031
|
|
|
|
membrane depolarization
|
GO:0051899 |
32 |
0.031
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
34 |
0.031
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.031
|
Rat |
|
|
lymphocyte proliferation
|
GO:0046651 |
29 |
0.031
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.031
|
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
46 |
0.031
|
|
|
|
exocytosis
|
GO:0006887 |
60 |
0.030
|
Mouse Rat |
|
|
vasculature development
|
GO:0001944 |
70 |
0.030
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.030
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.030
|
|
|
|
positive regulation of blood pressure by epinephrine norepinephrine
|
GO:0003321 |
2 |
0.030
|
|
|
|
regulation of endocrine process
|
GO:0044060 |
21 |
0.030
|
|
|
|
response to electrical stimulus
|
GO:0051602 |
56 |
0.030
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
62 |
0.030
|
|
|
|
vasodilation
|
GO:0042311 |
44 |
0.030
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
36 |
0.030
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.030
|
Rat |
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
17 |
0.030
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
52 |
0.030
|
|
|
|
ossification
|
GO:0001503 |
70 |
0.030
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
25 |
0.029
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.029
|
|
|
|
renal system process
|
GO:0003014 |
40 |
0.029
|
|
|
|
organ growth
|
GO:0035265 |
24 |
0.029
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.029
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.029
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.029
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
25 |
0.029
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
86 |
0.029
|
|
|
|
negative regulation of cell cell adhesion
|
GO:0022408 |
6 |
0.029
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.029
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
38 |
0.029
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.029
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
55 |
0.029
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
77 |
0.029
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.028
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
75 |
0.028
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.028
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.028
|
|
|
|
muscle cell development
|
GO:0055001 |
26 |
0.028
|
|
|
|
neuronal action potential
|
GO:0019228 |
35 |
0.028
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
22 |
0.028
|
|
|
|
muscle organ development
|
GO:0007517 |
50 |
0.028
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.028
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
10 |
0.028
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
87 |
0.027
|
|
|
|
developmental growth
|
GO:0048589 |
100 |
0.027
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
12 |
0.027
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
22 |
0.027
|
|
|
|
regulation of wound healing
|
GO:0061041 |
14 |
0.027
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
1 |
0.027
|
|
|
|
single organism behavior
|
GO:0044708 |
130 |
0.027
|
|
|
|
negative regulation of synaptic transmission glutamatergic
|
GO:0051967 |
8 |
0.027
|
|
|
|
cytokine production
|
GO:0001816 |
61 |
0.026
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.026
|
|
