Rattus norvegicus

0 known processes

Tcp11

t-complex protein 11

(Aliases: MGC95257)

Tcp11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.334
regulation of transcription dna templated GO:0006355 374 0.286
negative regulation of rna metabolic process GO:0051253 123 0.283
regulation of rna biosynthetic process GO:2001141 381 0.231
regulation of multicellular organismal development GO:2000026 376 0.226
response to molecule of bacterial origin GO:0002237 194 0.223
cellular response to oxygen containing compound GO:1901701 386 0.195
negative regulation of macromolecule metabolic process GO:0010605 260 0.190
regulation of rna metabolic process GO:0051252 391 0.186
apoptotic process GO:0006915 381 0.186
negative regulation of transcription dna templated GO:0045892 116 0.185
rna biosynthetic process GO:0032774 380 0.181
regulation of phosphate metabolic process GO:0019220 349 0.176
response to metal ion GO:0010038 253 0.171
programmed cell death GO:0012501 392 0.160
negative regulation of metabolic process GO:0009892 331 0.153
response to extracellular stimulus GO:0009991 380 0.139
negative regulation of gene expression GO:0010629 199 0.139
response to other organism GO:0051707 220 0.133
regulation of protein metabolic process GO:0051246 289 0.132
positive regulation of gene expression GO:0010628 244 0.132
response to estrogen GO:0043627 232 0.121
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.120
positive regulation of signaling GO:0023056 270 0.119
immune system process GO:0002376 204 0.115
rna metabolic process GO:0016070 406 0.106
positive regulation of cell proliferation GO:0008284 249 0.103
negative regulation of cellular biosynthetic process GO:0031327 161 0.099
cellular response to abiotic stimulus GO:0071214 85 0.095
response to inorganic substance GO:0010035 377 0.093
central nervous system development GO:0007417 311 0.092
regulation of programmed cell death GO:0043067 341 0.089
positive regulation of response to stimulus GO:0048584 285 0.089
regulation of apoptotic process GO:0042981 335 0.085
regulation of cellular protein metabolic process GO:0032268 267 0.083
reproductive process GO:0022414 372 0.080
positive regulation of transcription dna templated GO:0045893 197 0.077
response to cytokine GO:0034097 215 0.075
axonogenesis GO:0007409 71 0.074
negative regulation of rna biosynthetic process GO:1902679 118 0.074
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.072
positive regulation of multicellular organismal process GO:0051240 387 0.072
cellular response to cytokine stimulus GO:0071345 127 0.071
developmental process involved in reproduction GO:0003006 159 0.070
cell projection morphogenesis GO:0048858 123 0.069
tube development GO:0035295 89 0.069
positive regulation of phosphate metabolic process GO:0045937 262 0.068
response to biotic stimulus GO:0009607 226 0.068
organelle organization GO:0006996 266 0.067
protein phosphorylation GO:0006468 345 0.067
taxis GO:0042330 67 0.067
multicellular organismal water homeostasis GO:0050891 4 0.065
response to external biotic stimulus GO:0043207 221 0.064
positive regulation of protein metabolic process GO:0051247 178 0.064
response to bacterium GO:0009617 200 0.064
immune response GO:0006955 104 0.061
positive regulation of biosynthetic process GO:0009891 319 0.061
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.060
nucleic acid templated transcription GO:0097659 379 0.058
regulation of nucleic acid templated transcription GO:1903506 380 0.056
response to nutrient GO:0007584 248 0.056
tissue development GO:0009888 252 0.055
cell morphogenesis GO:0000902 142 0.055
transcription dna templated GO:0006351 377 0.053
neuron death GO:0070997 127 0.053
negative regulation of cellular metabolic process GO:0031324 281 0.052
cellular ketone metabolic process GO:0042180 51 0.052
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.052
negative regulation of nucleic acid templated transcription GO:1903507 117 0.051
regulation of nervous system development GO:0051960 264 0.050
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.049
cellular response to stress GO:0033554 269 0.048
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.048
epithelium development GO:0060429 96 0.048
response to wounding GO:0009611 254 0.047
response to acid chemical GO:0001101 222 0.047
cellular response to nitrogen compound GO:1901699 210 0.047
chemical homeostasis GO:0048878 292 0.047
inflammatory response GO:0006954 150 0.047
regulation of cellular ketone metabolic process GO:0010565 27 0.047
response to lipopolysaccharide GO:0032496 191 0.046
cellular response to gonadotropin stimulus GO:0071371 17 0.046
g protein coupled receptor signaling pathway GO:0007186 242 0.046
behavior GO:0007610 205 0.045
regulation of catalytic activity GO:0050790 304 0.045
positive regulation of cellular biosynthetic process GO:0031328 295 0.044
cellular component movement GO:0006928 248 0.044
regulation of protein phosphorylation GO:0001932 183 0.044
protein processing GO:0016485 68 0.044
regulation of secretion GO:0051046 224 0.044
multicellular organism reproduction GO:0032504 233 0.043
positive regulation of intracellular signal transduction GO:1902533 138 0.042
developmental growth GO:0048589 100 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.041
negative regulation of biosynthetic process GO:0009890 168 0.041
protein maturation GO:0051604 68 0.040
catabolic process GO:0009056 351 0.040
regulation of cell proliferation GO:0042127 359 0.040
response to ethanol GO:0045471 162 0.040
cell growth GO:0016049 104 0.039
circulatory system process GO:0003013 183 0.039
neuron fate commitment GO:0048663 4 0.039
response to purine containing compound GO:0014074 126 0.039
tissue regeneration GO:0042246 36 0.038
development of primary sexual characteristics GO:0045137 107 0.038
positive regulation of nucleic acid templated transcription GO:1903508 197 0.038
regulation of signal transduction GO:0009966 318 0.038
defense response GO:0006952 194 0.037
cellular response to endogenous stimulus GO:0071495 377 0.037
regulation of phosphorylation GO:0042325 248 0.037
response to nutrient levels GO:0031667 370 0.036
ribonucleoside metabolic process GO:0009119 174 0.036
negative regulation of multicellular organismal process GO:0051241 203 0.036
positive regulation of catalytic activity GO:0043085 184 0.035
locomotion GO:0040011 237 0.035
positive regulation of transport GO:0051050 245 0.034
cellular component morphogenesis GO:0032989 155 0.034
protein heterooligomerization GO:0051291 89 0.034
growth GO:0040007 165 0.034
positive regulation of neurogenesis GO:0050769 165 0.033
positive regulation of rna metabolic process GO:0051254 203 0.033
regulation of molecular function GO:0065009 398 0.033
regulation of cellular component movement GO:0051270 150 0.033
multi multicellular organism process GO:0044706 138 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
multi organism reproductive process GO:0044703 262 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
regulation of leukocyte differentiation GO:1902105 20 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.032
regulation of kinase activity GO:0043549 117 0.031
reproduction GO:0000003 245 0.031
regulation of protein modification process GO:0031399 194 0.031
brain development GO:0007420 247 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.030
single organism reproductive process GO:0044702 297 0.030
negative regulation of protein metabolic process GO:0051248 114 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
intracellular signal transduction GO:0035556 314 0.030
cellular response to peptide hormone stimulus GO:0071375 120 0.030
positive regulation of nervous system development GO:0051962 178 0.030
response to hypoxia GO:0001666 231 0.029
wound healing GO:0042060 122 0.029
sex differentiation GO:0007548 113 0.029
cellular response to mechanical stimulus GO:0071260 48 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
regulation of body fluid levels GO:0050878 90 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.028
negative regulation of apoptotic process GO:0043066 181 0.028
regulation of cellular component organization GO:0051128 368 0.028
cell fate determination GO:0001709 2 0.027
purine nucleoside metabolic process GO:0042278 169 0.027
neuron apoptotic process GO:0051402 88 0.027
thyroid gland development GO:0030878 1 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
negative regulation of molecular function GO:0044092 133 0.027
oxoacid metabolic process GO:0043436 290 0.027
response to oxidative stress GO:0006979 186 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
response to organophosphorus GO:0046683 102 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
negative regulation of cytokine production GO:0001818 16 0.026
regulation of cell differentiation GO:0045595 320 0.026
immunoglobulin mediated immune response GO:0016064 4 0.025
organ morphogenesis GO:0009887 75 0.025
negative regulation of protein processing GO:0010955 47 0.024
negative regulation of cell death GO:0060548 229 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
nucleotide catabolic process GO:0009166 139 0.024
response to hydrogen peroxide GO:0042542 89 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
regulation of response to external stimulus GO:0032101 106 0.024
muscle contraction GO:0006936 88 0.024
nucleoside metabolic process GO:0009116 179 0.024
cardiovascular system development GO:0072358 134 0.024
reproductive system development GO:0061458 128 0.023
regulation of metal ion transport GO:0010959 118 0.023
respiratory system development GO:0060541 45 0.023
cell part morphogenesis GO:0032990 123 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
cellular response to lipopolysaccharide GO:0071222 55 0.022
cellular response to acid chemical GO:0071229 75 0.022
cellular amine metabolic process GO:0044106 38 0.022
response to radiation GO:0009314 137 0.022
metal ion transport GO:0030001 289 0.022
male mating behavior GO:0060179 3 0.022
axon development GO:0061564 96 0.022
axis specification GO:0009798 4 0.022
muscle structure development GO:0061061 87 0.022
neuron projection morphogenesis GO:0048812 122 0.022
response to decreased oxygen levels GO:0036293 237 0.022
cation transport GO:0006812 382 0.022
peptidyl amino acid modification GO:0018193 126 0.022
response to retinoic acid GO:0032526 63 0.022
multicellular organismal homeostasis GO:0048871 49 0.021
blood circulation GO:0008015 183 0.021
circadian rhythm GO:0007623 88 0.021
response to camp GO:0051591 91 0.021
response to toxic substance GO:0009636 133 0.021
response to calcium ion GO:0051592 59 0.021
chemotaxis GO:0006935 66 0.021
organophosphate metabolic process GO:0019637 370 0.021
regulation of neuron death GO:1901214 115 0.021
carbohydrate homeostasis GO:0033500 75 0.020
regulation of immune system process GO:0002682 123 0.020
sodium ion transmembrane transport GO:0035725 67 0.020
regulation of neuron differentiation GO:0045664 208 0.020
forebrain development GO:0030900 98 0.020
dna metabolic process GO:0006259 96 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
nucleoside triphosphate metabolic process GO:0009141 144 0.020
negative regulation of cell differentiation GO:0045596 99 0.020
negative regulation of developmental process GO:0051093 125 0.020
lung development GO:0030324 43 0.020
rhythmic process GO:0048511 156 0.020
neuron projection guidance GO:0097485 24 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.020
regulation of neurogenesis GO:0050767 247 0.020
regulation of cell motility GO:2000145 131 0.019
response to ketone GO:1901654 182 0.019
gonad development GO:0008406 104 0.019
organic anion transport GO:0015711 132 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
hormone metabolic process GO:0042445 69 0.019
negative regulation of chronic inflammatory response GO:0002677 2 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
macromolecular complex assembly GO:0065003 273 0.019
cell projection organization GO:0030030 302 0.019
response to histamine GO:0034776 3 0.019
positive regulation of protein modification process GO:0031401 142 0.019
regulation of system process GO:0044057 208 0.019
carboxylic acid transport GO:0046942 115 0.019
reproductive behavior GO:0019098 10 0.018
cytokine production GO:0001816 61 0.018
protein localization GO:0008104 191 0.018
camera type eye development GO:0043010 48 0.018
regulation of protein kinase activity GO:0045859 105 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.018
neutrophil apoptotic process GO:0001781 4 0.018
regulation of response to stress GO:0080134 126 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
negative regulation of signaling GO:0023057 157 0.017
response to oxygen levels GO:0070482 265 0.017
positive regulation of response to food GO:0032097 3 0.017
transmission of nerve impulse GO:0019226 42 0.017
regulation of protein processing GO:0070613 50 0.017
calcium ion homeostasis GO:0055074 162 0.017
positive regulation of protein transport GO:0051222 41 0.017
nitrogen compound transport GO:0071705 229 0.017
protein complex assembly GO:0006461 263 0.017
salivary gland development GO:0007431 3 0.017
organic acid transport GO:0015849 116 0.017
leukocyte activation GO:0045321 76 0.017
lipid localization GO:0010876 62 0.016
cellular homeostasis GO:0019725 252 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
response to peptide GO:1901652 292 0.016
anatomical structure formation involved in morphogenesis GO:0048646 83 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
cellular response to organonitrogen compound GO:0071417 197 0.015
protein complex subunit organization GO:0071822 302 0.015
cellular catabolic process GO:0044248 295 0.015
response to glucocorticoid GO:0051384 223 0.015
cellular response to molecule of bacterial origin GO:0071219 56 0.015
negative regulation of response to external stimulus GO:0032102 37 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
magnesium ion homeostasis GO:0010960 2 0.015
regulation of cell growth GO:0001558 85 0.015
axon guidance GO:0007411 24 0.015
response to cgmp GO:0070305 3 0.015
eye morphogenesis GO:0048592 4 0.015
cellular response to interleukin 1 GO:0071347 37 0.015
regulation of cell projection organization GO:0031344 175 0.015
purine containing compound metabolic process GO:0072521 253 0.015
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 3 0.015
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.015
positive regulation of cell development GO:0010720 176 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
negative regulation of transport GO:0051051 136 0.014
proteolysis GO:0006508 175 0.014
immune effector process GO:0002252 53 0.014
neuron differentiation GO:0030182 368 0.014
regeneration GO:0031099 163 0.014
response to tumor necrosis factor GO:0034612 56 0.014
camera type eye morphogenesis GO:0048593 2 0.014
defense response to gram negative bacterium GO:0050829 3 0.014
synaptic transmission glycinergic GO:0060012 2 0.014
neurological system process GO:0050877 219 0.014
hematopoietic progenitor cell differentiation GO:0002244 2 0.014
axon extension GO:0048675 26 0.014
positive regulation of cell communication GO:0010647 271 0.014
female pregnancy GO:0007565 122 0.014
regulation of locomotion GO:0040012 148 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
positive regulation of cellular component organization GO:0051130 200 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
regulation of muscle tissue development GO:1901861 25 0.013
regulation of behavior GO:0050795 61 0.013
regulation of protein serine threonine kinase activity GO:0071900 64 0.013
regulation of defense response GO:0031347 68 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
nucleoside catabolic process GO:0009164 126 0.013
negative regulation of cell communication GO:0010648 158 0.013
positive regulation of signal transduction GO:0009967 175 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
cognition GO:0050890 92 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
gtp metabolic process GO:0046039 72 0.013
sleep GO:0030431 30 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
transmembrane transport GO:0055085 412 0.013
amine metabolic process GO:0009308 38 0.013
positive regulation of cell death GO:0010942 184 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
regulation of cell development GO:0060284 263 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
chronic inflammatory response GO:0002544 16 0.013
cellular chemical homeostasis GO:0055082 247 0.013
purine containing compound catabolic process GO:0072523 138 0.013
regulation of blood pressure GO:0008217 83 0.013
sensory perception GO:0007600 101 0.012
reproductive structure development GO:0048608 128 0.012
regulation of membrane potential GO:0042391 110 0.012
positive regulation of catabolic process GO:0009896 78 0.012
heart development GO:0007507 72 0.012
positive regulation of transferase activity GO:0051347 81 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
neuron projection extension GO:1990138 26 0.012
response to lithium ion GO:0010226 28 0.012
response to osmotic stress GO:0006970 42 0.012
negative regulation of immune response GO:0050777 15 0.012
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.012
muscle cell proliferation GO:0033002 84 0.012
response to reactive oxygen species GO:0000302 120 0.012
cell type specific apoptotic process GO:0097285 134 0.012
positive regulation of developmental process GO:0051094 283 0.012
cytoskeleton organization GO:0007010 111 0.012
response to food GO:0032094 27 0.012
lipid storage GO:0019915 1 0.012
gamete generation GO:0007276 124 0.012
actin filament depolymerization GO:0030042 3 0.012
regulation of catabolic process GO:0009894 113 0.011
leukocyte cell cell adhesion GO:0007159 4 0.011
macromolecule catabolic process GO:0009057 58 0.011
odontogenesis GO:0042476 32 0.011
ras protein signal transduction GO:0007265 29 0.011
regulation of membrane repolarization GO:0060306 1 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
regulation of circadian sleep wake cycle wakefulness GO:0010840 2 0.011
regulation of transferase activity GO:0051338 123 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
secretion GO:0046903 307 0.011
regulation of response to wounding GO:1903034 69 0.011
cellular ion homeostasis GO:0006873 184 0.011
regulation of protein transport GO:0051223 68 0.011
head development GO:0060322 247 0.011
regulation of protein localization GO:0032880 81 0.011
negative regulation of immune system process GO:0002683 39 0.011
circadian sleep wake cycle wakefulness GO:0042746 2 0.011
aromatic compound catabolic process GO:0019439 168 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
regulation of growth GO:0040008 105 0.011
cellular response to follicle stimulating hormone stimulus GO:0071372 13 0.011
central nervous system neuron differentiation GO:0021953 17 0.011
positive regulation of intracellular protein transport GO:0090316 20 0.011
lens development in camera type eye GO:0002088 13 0.011
eye development GO:0001654 50 0.011
negative regulation of neuron death GO:1901215 69 0.011
cellular response to peptide GO:1901653 133 0.010
synaptic transmission GO:0007268 235 0.010
regulation of heart growth GO:0060420 12 0.010
memory GO:0007613 54 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
regulation of proteolysis GO:0030162 66 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
response to carbohydrate GO:0009743 183 0.010
lymphocyte activation GO:0046649 43 0.010
ion transmembrane transport GO:0034220 365 0.010
respiratory tube development GO:0030323 43 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
regulation of cellular component size GO:0032535 51 0.010

Tcp11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.058
disease of anatomical entity DOID:7 0 0.058
sensory system disease DOID:0050155 0 0.052
eye and adnexa disease DOID:1492 0 0.052
eye disease DOID:5614 0 0.029
retinal disease DOID:5679 0 0.022
urinary system disease DOID:18 0 0.021
kidney disease DOID:557 0 0.021
muscular disease DOID:0080000 0 0.019
myopathy DOID:423 0 0.019
musculoskeletal system disease DOID:17 0 0.019
muscle tissue disease DOID:66 0 0.019
long qt syndrome DOID:2843 0 0.019
impaired renal function disease DOID:11705 0 0.019
renal tubular transport disease DOID:447 0 0.016
cardiovascular system disease DOID:1287 0 0.015
color blindness DOID:13399 0 0.013
blindness DOID:1432 0 0.013
substance related disorder DOID:303 0 0.011
substance dependence DOID:9973 0 0.011
nicotine dependence DOID:0050742 0 0.011
disease of mental health DOID:150 0 0.011
retinal degeneration DOID:8466 0 0.011