Rattus norvegicus

0 known processes

Tff2

trefoil factor 2

Tff2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient GO:0007584 248 0.740
tissue development GO:0009888 252 0.390
response to extracellular stimulus GO:0009991 380 0.343
response to nutrient levels GO:0031667 370 0.312
apoptotic process GO:0006915 381 0.238
lipid metabolic process GO:0006629 283 0.225
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.212
single organism reproductive process GO:0044702 297 0.175
cellular lipid metabolic process GO:0044255 208 0.128
regulation of cell proliferation GO:0042127 359 0.126
Mouse
epithelium development GO:0060429 96 0.124
nucleic acid templated transcription GO:0097659 379 0.112
positive regulation of multicellular organismal process GO:0051240 387 0.105
response to lipopolysaccharide GO:0032496 191 0.101
response to cytokine GO:0034097 215 0.100
Mouse
anatomical structure morphogenesis GO:0009653 298 0.099
transcription dna templated GO:0006351 377 0.096
response to glucocorticoid GO:0051384 223 0.095
regulation of blood vessel size GO:0050880 89 0.093
multi multicellular organism process GO:0044706 138 0.091
regulation of rna metabolic process GO:0051252 391 0.091
regulation of neurogenesis GO:0050767 247 0.091
rna metabolic process GO:0016070 406 0.090
cation transport GO:0006812 382 0.089
reproductive process GO:0022414 372 0.087
leydig cell differentiation GO:0033327 8 0.087
regulation of apoptotic process GO:0042981 335 0.084
negative regulation of cell death GO:0060548 229 0.083
metal ion transport GO:0030001 289 0.082
response to mineralocorticoid GO:0051385 49 0.081
epithelial cell differentiation GO:0030855 71 0.077
regulation of cellular ketone metabolic process GO:0010565 27 0.076
oxoacid metabolic process GO:0043436 290 0.076
cellular amino acid metabolic process GO:0006520 107 0.075
regulation of cell differentiation GO:0045595 320 0.075
positive regulation of biosynthetic process GO:0009891 319 0.074
cell projection organization GO:0030030 302 0.072
carboxylic acid metabolic process GO:0019752 289 0.071
regulation of nucleic acid templated transcription GO:1903506 380 0.071
positive regulation of cellular protein metabolic process GO:0032270 167 0.070
sodium ion transmembrane transport GO:0035725 67 0.070
regulation of hormone levels GO:0010817 187 0.069
female pregnancy GO:0007565 122 0.068
rna biosynthetic process GO:0032774 380 0.068
reproduction GO:0000003 245 0.064
organic acid metabolic process GO:0006082 292 0.064
regulation of multicellular organismal development GO:2000026 376 0.062
positive regulation of molecular function GO:0044093 230 0.061
developmental process involved in reproduction GO:0003006 159 0.061
neuron differentiation GO:0030182 368 0.060
blood circulation GO:0008015 183 0.060
transcription from rna polymerase ii promoter GO:0006366 252 0.059
protein phosphorylation GO:0006468 345 0.059
positive regulation of catalytic activity GO:0043085 184 0.059
positive regulation of gene expression GO:0010628 244 0.059
regulation of cellular protein metabolic process GO:0032268 267 0.058
response to vitamin GO:0033273 131 0.057
multi organism reproductive process GO:0044703 262 0.057
response to corticosteroid GO:0031960 235 0.057
neuron projection development GO:0031175 273 0.057
response to bacterium GO:0009617 200 0.057
positive regulation of nervous system development GO:0051962 178 0.056
cellular component movement GO:0006928 248 0.056
Mouse
cell cell signaling GO:0007267 335 0.056
cellular ketone metabolic process GO:0042180 51 0.055
lipid biosynthetic process GO:0008610 128 0.054
circadian rhythm GO:0007623 88 0.053
regulation of programmed cell death GO:0043067 341 0.053
programmed cell death GO:0012501 392 0.053
response to retinoic acid GO:0032526 63 0.053
regulation of nervous system development GO:0051960 264 0.051
reproductive system development GO:0061458 128 0.049
positive regulation of cell differentiation GO:0045597 217 0.049
positive regulation of transcription dna templated GO:0045893 197 0.049
cell part morphogenesis GO:0032990 123 0.049
regulation of transcription dna templated GO:0006355 374 0.048
response to radiation GO:0009314 137 0.048
sexual reproduction GO:0019953 148 0.047
l glutamate import GO:0051938 2 0.047
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.047
single organism biosynthetic process GO:0044711 342 0.047
regulation of cell development GO:0060284 263 0.047
positive regulation of cellular biosynthetic process GO:0031328 295 0.046
skeletal system development GO:0001501 41 0.046
response to molecule of bacterial origin GO:0002237 194 0.046
cellular response to abiotic stimulus GO:0071214 85 0.046
regulation of cellular amine metabolic process GO:0033238 8 0.045
rhythmic process GO:0048511 156 0.045
regulation of metal ion transport GO:0010959 118 0.045
cell projection morphogenesis GO:0048858 123 0.045
response to acid chemical GO:0001101 222 0.044
positive regulation of programmed cell death GO:0043068 157 0.043
glial cell differentiation GO:0010001 65 0.042
ion transmembrane transport GO:0034220 365 0.041
multicellular organism reproduction GO:0032504 233 0.041
monovalent inorganic cation transport GO:0015672 172 0.041
response to purine containing compound GO:0014074 126 0.040
regulation of phosphate metabolic process GO:0019220 349 0.039
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 197 0.038
positive regulation of protein modification process GO:0031401 142 0.038
response to other organism GO:0051707 220 0.038
cellular response to hormone stimulus GO:0032870 247 0.038
response to biotic stimulus GO:0009607 226 0.038
cellular response to external stimulus GO:0071496 118 0.038
regulation of transferase activity GO:0051338 123 0.037
amine metabolic process GO:0009308 38 0.037
cellular ion homeostasis GO:0006873 184 0.036
response to peptide GO:1901652 292 0.036
Rat
protein complex assembly GO:0006461 263 0.036
positive regulation of protein phosphorylation GO:0001934 135 0.036
gliogenesis GO:0042063 93 0.034
organ morphogenesis GO:0009887 75 0.034
central nervous system development GO:0007417 311 0.034
regeneration GO:0031099 163 0.034
positive regulation of apoptotic process GO:0043065 154 0.034
regulation of molecular function GO:0065009 398 0.034
response to peptide hormone GO:0043434 278 0.033
Rat
positive regulation of cell proliferation GO:0008284 249 0.032
Mouse
homeostatic process GO:0042592 331 0.032
Rat
cellular response to stress GO:0033554 269 0.032
positive regulation of cell death GO:0010942 184 0.032
regulation of cell growth GO:0001558 85 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
aging GO:0007568 241 0.032
respiratory system development GO:0060541 45 0.031
regulation of cell projection organization GO:0031344 175 0.031
regulation of muscle system process GO:0090257 79 0.030
vascular process in circulatory system GO:0003018 96 0.030
intracellular transport GO:0046907 185 0.030
response to inorganic substance GO:0010035 377 0.030
Rat
regulation of cellular component organization GO:0051128 368 0.030
response to external biotic stimulus GO:0043207 221 0.030
regulation of anatomical structure size GO:0090066 135 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
positive regulation of rna metabolic process GO:0051254 203 0.030
neuron development GO:0048666 286 0.029
regulation of neuron differentiation GO:0045664 208 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
regulation of catalytic activity GO:0050790 304 0.029
positive regulation of neurogenesis GO:0050769 165 0.029
protein oligomerization GO:0051259 191 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
cellular response to peptide hormone stimulus GO:0071375 120 0.028
negative regulation of apoptotic process GO:0043066 181 0.028
cell growth GO:0016049 104 0.028
cellular response to acid chemical GO:0071229 75 0.027
cation transmembrane transport GO:0098655 263 0.027
single organism intracellular transport GO:1902582 166 0.027
cellular component morphogenesis GO:0032989 155 0.026
amino acid transport GO:0006865 70 0.026
heart morphogenesis GO:0003007 3 0.026
regulation of immune system process GO:0002682 123 0.026
Mouse
hormone metabolic process GO:0042445 69 0.026
cellular amine metabolic process GO:0044106 38 0.025
regulation of organ formation GO:0003156 2 0.025
organic acid transport GO:0015849 116 0.025
endothelial cell differentiation GO:0045446 9 0.024
positive regulation of kinase activity GO:0033674 77 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
dicarboxylic acid transport GO:0006835 34 0.024
response to metal ion GO:0010038 253 0.024
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
regulation of protein metabolic process GO:0051246 289 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
regulation of growth GO:0040008 105 0.023
circulatory system development GO:0072359 134 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
response to oxygen levels GO:0070482 265 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
response to alkaloid GO:0043279 132 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
regulation of protein kinase activity GO:0045859 105 0.023
neuron projection morphogenesis GO:0048812 122 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
positive regulation of cell communication GO:0010647 271 0.022
Mouse
peptidyl amino acid modification GO:0018193 126 0.022
response to wounding GO:0009611 254 0.022
Mouse
cellular response to peptide GO:1901653 133 0.022
positive regulation of blood circulation GO:1903524 65 0.022
chemical homeostasis GO:0048878 292 0.022
organophosphate metabolic process GO:0019637 370 0.022
growth GO:0040007 165 0.022
regulation of kinase activity GO:0043549 117 0.021
muscle system process GO:0003012 115 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
behavior GO:0007610 205 0.021
response to increased oxygen levels GO:0036296 45 0.021
cell adhesion GO:0007155 110 0.021
sex differentiation GO:0007548 113 0.021
intracellular signal transduction GO:0035556 314 0.021
Mouse
response to carbohydrate GO:0009743 183 0.020
response to antibiotic GO:0046677 39 0.020
locomotor rhythm GO:0045475 1 0.020
positive regulation of cell development GO:0010720 176 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
Mouse
response to insulin GO:0032868 133 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
biological adhesion GO:0022610 110 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
macromolecular complex assembly GO:0065003 273 0.019
regulation of protein modification process GO:0031399 194 0.019
ion homeostasis GO:0050801 212 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
regulation of neuron projection development GO:0010975 161 0.019
peptidyl tyrosine modification GO:0018212 72 0.019
regulation of peptidase activity GO:0052547 55 0.019
regulation of homotypic cell cell adhesion GO:0034110 4 0.019
nitrogen compound transport GO:0071705 229 0.019
endothelium development GO:0003158 12 0.019
regulation of blood pressure GO:0008217 83 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
mesoderm development GO:0007498 2 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
tissue morphogenesis GO:0048729 22 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
Mouse
organelle organization GO:0006996 266 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
regulation of system process GO:0044057 208 0.019
Mouse
negative regulation of rna metabolic process GO:0051253 123 0.019
urinary bladder smooth muscle contraction GO:0014832 4 0.019
tube development GO:0035295 89 0.019
response to toxic substance GO:0009636 133 0.018
metal ion homeostasis GO:0055065 186 0.018
cellular chemical homeostasis GO:0055082 247 0.018
response to estrogen GO:0043627 232 0.018
positive regulation of lipid biosynthetic process GO:0046889 25 0.018
positive regulation of transferase activity GO:0051347 81 0.018
reproductive structure development GO:0048608 128 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
response to hyperoxia GO:0055093 45 0.018
positive regulation of long term synaptic potentiation GO:1900273 4 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.018
hepaticobiliary system development GO:0061008 90 0.018
rhombomere development GO:0021546 1 0.018
sensory perception GO:0007600 101 0.018
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.018
vasoconstriction GO:0042310 54 0.018
carbohydrate homeostasis GO:0033500 75 0.018
positive regulation of transmembrane transport GO:0034764 25 0.018
negative regulation of biosynthetic process GO:0009890 168 0.017
cellular response to lipid GO:0071396 201 0.017
response to growth factor GO:0070848 189 0.017
response to monosaccharide GO:0034284 159 0.017
tube formation GO:0035148 3 0.017
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.017
divalent metal ion transport GO:0070838 132 0.017
positive regulation of signaling GO:0023056 270 0.017
Mouse
transmembrane transport GO:0055085 412 0.017
steroid metabolic process GO:0008202 73 0.017
negative regulation of gene expression GO:0010629 199 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
Mouse
negative regulation of multicellular organismal process GO:0051241 203 0.017
Mouse
heart contraction GO:0060047 57 0.017
regulation of hydrolase activity GO:0051336 143 0.017
l amino acid transport GO:0015807 21 0.017
muscle structure development GO:0061061 87 0.017
response to glucose GO:0009749 136 0.017
regulation of vesicle mediated transport GO:0060627 81 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
Mouse
regulation of blood circulation GO:1903522 110 0.016
organ induction GO:0001759 1 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
negative regulation of molecular function GO:0044092 133 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
embryonic skeletal system development GO:0048706 3 0.016
calcium ion homeostasis GO:0055074 162 0.016
morphogenesis of embryonic epithelium GO:0016331 3 0.016
response to oxidative stress GO:0006979 186 0.016
cellular response to insulin stimulus GO:0032869 81 0.015
head development GO:0060322 247 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
cell cycle GO:0007049 101 0.015
macromolecule localization GO:0033036 252 0.015
alpha amino acid metabolic process GO:1901605 71 0.015
response to hexose GO:0009746 144 0.015
regulation of membrane potential GO:0042391 110 0.015
optic nerve development GO:0021554 3 0.015
actin mediated cell contraction GO:0070252 12 0.015
maternal process involved in female pregnancy GO:0060135 38 0.015
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.015
activation of cysteine type endopeptidase activity GO:0097202 4 0.015
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.015
negative regulation of developmental process GO:0051093 125 0.014
vesicle mediated transport GO:0016192 181 0.014
regulation of tube size GO:0035150 89 0.014
cellular homeostasis GO:0019725 252 0.014
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.014
response to fibroblast growth factor GO:0071774 29 0.014
regulation of behavior GO:0050795 61 0.014
regulation of lipid metabolic process GO:0019216 68 0.014
response to reactive oxygen species GO:0000302 120 0.014
response to organophosphorus GO:0046683 102 0.014
n methyl d aspartate receptor clustering GO:0097114 2 0.014
chemotaxis GO:0006935 66 0.014
cellular component biogenesis GO:0044085 368 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
immune system process GO:0002376 204 0.014
Mouse
positive regulation of growth GO:0045927 55 0.014
regulation of saliva secretion GO:0046877 3 0.013
negative regulation of cell development GO:0010721 82 0.013
actin filament based movement GO:0030048 16 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
morphogenesis of an epithelium GO:0002009 20 0.013
multicellular organism growth GO:0035264 1 0.013
regulation of stem cell differentiation GO:2000736 2 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
urogenital system development GO:0001655 78 0.013
renal system development GO:0072001 67 0.013
regulation of activation of janus kinase activity GO:0010533 1 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
cytoplasmic transport GO:0016482 115 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
regulation of metanephros development GO:0072215 4 0.013
regulation of transmembrane transport GO:0034762 122 0.013
respiratory tube development GO:0030323 43 0.013
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.013
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
carboxylic acid transport GO:0046942 115 0.012
glucose homeostasis GO:0042593 75 0.012
hemopoiesis GO:0030097 34 0.012
single organismal cell cell adhesion GO:0016337 42 0.012
heart process GO:0003015 57 0.012
cellular component assembly GO:0022607 360 0.012
gamete generation GO:0007276 124 0.012
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.012
response to vitamin a GO:0033189 36 0.012
regulation of embryonic development GO:0045995 2 0.012
fatty acid metabolic process GO:0006631 99 0.012
lipid storage GO:0019915 1 0.012
negative regulation of cell communication GO:0010648 158 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
embryonic skeletal system morphogenesis GO:0048704 3 0.012
insecticide metabolic process GO:0017143 4 0.012
glomerular mesangium development GO:0072109 4 0.012
cell migration GO:0016477 197 0.012
Mouse
heart development GO:0007507 72 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
response to fatty acid GO:0070542 65 0.012
anion transport GO:0006820 178 0.012
regulation of organelle organization GO:0033043 80 0.012
single organism behavior GO:0044708 130 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
hormone secretion GO:0046879 115 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
cellular catabolic process GO:0044248 295 0.011
ossification GO:0001503 70 0.011
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.011
organic anion transport GO:0015711 132 0.011
eye morphogenesis GO:0048592 4 0.011
response to mechanical stimulus GO:0009612 134 0.011
positive regulation of developmental process GO:0051094 283 0.011
cellular response to oxidative stress GO:0034599 76 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
cardiovascular system development GO:0072358 134 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.011
renal system process GO:0003014 40 0.011
small molecule biosynthetic process GO:0044283 124 0.011
limb morphogenesis GO:0035108 4 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
organic acid biosynthetic process GO:0016053 83 0.011
response to blue light GO:0009637 1 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
nucleoside metabolic process GO:0009116 179 0.011
cell morphogenesis GO:0000902 142 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
Mouse
action potential GO:0001508 54 0.011
regulation of transporter activity GO:0032409 50 0.011
response to light stimulus GO:0009416 52 0.011
positive regulation of leukocyte activation GO:0002696 30 0.011
establishment of protein localization GO:0045184 141 0.011
peptide transport GO:0015833 97 0.011
connective tissue development GO:0061448 33 0.011
ovulation cycle GO:0042698 67 0.011
regulation of cell adhesion GO:0030155 52 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
protein maturation GO:0051604 68 0.011
male mating behavior GO:0060179 3 0.010
anion transmembrane transport GO:0098656 77 0.010
response to hypoxia GO:0001666 231 0.010
negative regulation of signal transduction GO:0009968 83 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
neuronal action potential GO:0019228 35 0.010
endocytosis GO:0006897 84 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
regulation of heart contraction GO:0008016 48 0.010
protein complex biogenesis GO:0070271 263 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
cardiac muscle contraction GO:0060048 27 0.010
regulation of mapk cascade GO:0043408 116 0.010
Mouse
respiratory system process GO:0003016 3 0.010
sensory organ development GO:0007423 74 0.010
thyroid gland development GO:0030878 1 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010

Tff2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.045
disease of anatomical entity DOID:7 0 0.045
musculoskeletal system disease DOID:17 0 0.031
sensory system disease DOID:0050155 0 0.025
eye disease DOID:5614 0 0.025
eye and adnexa disease DOID:1492 0 0.025
urinary system disease DOID:18 0 0.019
kidney disease DOID:557 0 0.013
endocrine system disease DOID:28 0 0.012
disease of metabolism DOID:0014667 0 0.011
retinal degeneration DOID:8466 0 0.010
retinal disease DOID:5679 0 0.010