Rattus norvegicus

105 known processes

Tgfbr1

transforming growth factor, beta receptor 1

(Aliases: MGC93659)

Tgfbr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein phosphorylation GO:0006468 345 0.370
regulation of molecular function GO:0065009 398 0.359
Human Mouse
regulation of protein modification process GO:0031399 194 0.273
Human Rat Fly
regulation of protein phosphorylation GO:0001932 183 0.211
Human Rat Fly
protein autophosphorylation GO:0046777 66 0.205
regulation of cellular protein metabolic process GO:0032268 267 0.190
Human Rat Fly
cell motility GO:0048870 202 0.190
Human Mouse
neuron development GO:0048666 286 0.186
Fly
regulation of rna biosynthetic process GO:2001141 381 0.173
Human Rat Worm Fly
regulation of cell proliferation GO:0042127 359 0.157
Human Mouse Rat
transcription dna templated GO:0006351 377 0.155
Human Rat Worm
regulation of cellular component organization GO:0051128 368 0.145
Human Mouse Worm
regulation of nucleic acid templated transcription GO:1903506 380 0.144
Human Rat Worm Fly
positive regulation of catalytic activity GO:0043085 184 0.141
Human
cellular component movement GO:0006928 248 0.138
Human Mouse Fly
embryonic skeletal system development GO:0048706 3 0.130
Mouse
rna metabolic process GO:0016070 406 0.128
Human Rat Worm
regulation of cellular component movement GO:0051270 150 0.125
Human
positive regulation of multicellular organismal process GO:0051240 387 0.121
Worm
tissue development GO:0009888 252 0.119
programmed cell death GO:0012501 392 0.117
Human Mouse Rat
regulation of catalytic activity GO:0050790 304 0.114
Human
cell projection organization GO:0030030 302 0.113
Mouse Fly
regulation of apoptotic process GO:0042981 335 0.113
Human Mouse Rat
regulation of phosphorus metabolic process GO:0051174 349 0.107
Human Rat Fly
positive regulation of response to stimulus GO:0048584 285 0.106
Human Rat Fly
rna biosynthetic process GO:0032774 380 0.104
Human Rat Worm
neuron projection morphogenesis GO:0048812 122 0.104
Fly
regulation of protein metabolic process GO:0051246 289 0.103
Human Rat Worm Fly
peptidyl amino acid modification GO:0018193 126 0.100
Human
intracellular signal transduction GO:0035556 314 0.100
Human Rat
aging GO:0007568 241 0.099
locomotion GO:0040011 237 0.099
Human Mouse Fly
regulation of phosphorylation GO:0042325 248 0.098
Human Rat Fly
negative regulation of cellular metabolic process GO:0031324 281 0.096
Fly
regulation of transcription dna templated GO:0006355 374 0.095
Human Rat Worm Fly
regulation of multicellular organismal development GO:2000026 376 0.091
macromolecule localization GO:0033036 252 0.090
Human Worm
cellular component biogenesis GO:0044085 368 0.089
Mouse Rat
positive regulation of programmed cell death GO:0043068 157 0.086
Human
protein complex subunit organization GO:0071822 302 0.085
Mouse Rat
regulation of programmed cell death GO:0043067 341 0.084
Human Mouse Rat
neuron differentiation GO:0030182 368 0.082
Mouse Fly
positive regulation of rna metabolic process GO:0051254 203 0.082
Human Rat Worm
localization of cell GO:0051674 202 0.081
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 295 0.081
Human Rat Worm
negative regulation of phosphorus metabolic process GO:0010563 80 0.080
transcription from rna polymerase ii promoter GO:0006366 252 0.080
Rat Worm
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.080
Human Rat Worm
positive regulation of rna biosynthetic process GO:1902680 197 0.079
Human Rat Worm
regulation of cell differentiation GO:0045595 320 0.077
cell migration GO:0016477 197 0.076
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.076
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.073
Human Rat Worm
cellular amino acid metabolic process GO:0006520 107 0.073
signal transduction by phosphorylation GO:0023014 144 0.071
Human Rat
cytoskeleton organization GO:0007010 111 0.070
transmembrane transport GO:0055085 412 0.070
regulation of cell motility GO:2000145 131 0.070
cell morphogenesis involved in differentiation GO:0000904 119 0.070
Human Fly
regulation of hydrolase activity GO:0051336 143 0.070
negative regulation of metabolic process GO:0009892 331 0.069
Fly
endocytosis GO:0006897 84 0.069
Rat
cellular component assembly GO:0022607 360 0.069
Mouse Rat
growth GO:0040007 165 0.068
Human Rat Worm
positive regulation of nucleic acid templated transcription GO:1903508 197 0.068
Human Rat Worm
cellular response to endogenous stimulus GO:0071495 377 0.067
positive regulation of gene expression GO:0010628 244 0.067
Human Rat Worm
positive regulation of phosphate metabolic process GO:0045937 262 0.066
Human Rat Fly
transforming growth factor beta receptor complex assembly GO:0007181 2 0.065
Rat
cation transport GO:0006812 382 0.065
protein complex assembly GO:0006461 263 0.065
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.065
central nervous system development GO:0007417 311 0.064
Rat Fly
negative regulation of gene expression GO:0010629 199 0.063
positive regulation of phosphorylation GO:0042327 177 0.063
Human Rat Fly
response to extracellular stimulus GO:0009991 380 0.063
Rat
negative regulation of growth GO:0045926 37 0.063
Rat
macromolecular complex assembly GO:0065003 273 0.062
Rat
response to corticosteroid GO:0031960 235 0.061
Rat
regulation of kinase activity GO:0043549 117 0.061
Human
cell growth GO:0016049 104 0.061
Human
organelle organization GO:0006996 266 0.061
immune system process GO:0002376 204 0.060
Mouse Worm
positive regulation of cellular component organization GO:0051130 200 0.060
Mouse
response to other organism GO:0051707 220 0.060
Worm
positive regulation of biosynthetic process GO:0009891 319 0.060
Human Rat Worm
regulation of response to external stimulus GO:0032101 106 0.059
Rat
regulation of protein kinase activity GO:0045859 105 0.058
Human
nucleic acid templated transcription GO:0097659 379 0.058
Human Rat Worm
mapk cascade GO:0000165 140 0.058
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.058
Rat Worm Fly
positive regulation of cell migration GO:0030335 96 0.058
regulation of neurogenesis GO:0050767 247 0.056
regulation of intracellular signal transduction GO:1902531 218 0.056
Human
response to decreased oxygen levels GO:0036293 237 0.055
regulation of locomotion GO:0040012 148 0.054
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.054
Human Rat Worm
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.054
regulation of nervous system development GO:0051960 264 0.053
positive regulation of molecular function GO:0044093 230 0.053
Human
apoptotic process GO:0006915 381 0.052
Human Mouse Rat
amine metabolic process GO:0009308 38 0.052
positive regulation of cell death GO:0010942 184 0.052
Human
protein maturation GO:0051604 68 0.052
positive regulation of cell motility GO:2000147 97 0.052
regulation of cellular amine metabolic process GO:0033238 8 0.052
macromolecular complex subunit organization GO:0043933 339 0.051
Mouse Rat
response to toxic substance GO:0009636 133 0.051
response to nutrient levels GO:0031667 370 0.051
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.051
positive regulation of protein modification process GO:0031401 142 0.051
Human Rat Fly
regulation of phosphate metabolic process GO:0019220 349 0.051
Human Rat Fly
positive regulation of cell differentiation GO:0045597 217 0.051
negative regulation of cell communication GO:0010648 158 0.050
Human
cell type specific apoptotic process GO:0097285 134 0.050
cellular response to glucocorticoid stimulus GO:0071385 68 0.050
Rat
positive regulation of protein kinase activity GO:0045860 73 0.049
Human
regulation of rna metabolic process GO:0051252 391 0.049
Human Rat Worm Fly
regulation of neuron differentiation GO:0045664 208 0.048
biological adhesion GO:0022610 110 0.048
Worm
positive regulation of phosphorus metabolic process GO:0010562 262 0.048
Human Rat Fly
regulation of cellular amino acid metabolic process GO:0006521 2 0.047
actin filament based process GO:0030029 86 0.047
cellular response to corticosteroid stimulus GO:0071384 69 0.047
Rat
regulation of cell development GO:0060284 263 0.047
negative regulation of molecular function GO:0044092 133 0.047
response to estrogen GO:0043627 232 0.046
multi organism reproductive process GO:0044703 262 0.046
negative regulation of muscle organ development GO:0048635 8 0.045
Rat
cellular ketone metabolic process GO:0042180 51 0.045
regulation of transforming growth factor beta3 production GO:0032910 2 0.045
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.045
protein processing GO:0016485 68 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
cellular amine metabolic process GO:0044106 38 0.044
neuron projection development GO:0031175 273 0.044
Fly
positive regulation of transcription dna templated GO:0045893 197 0.044
Human Rat Worm
regulation of cell projection organization GO:0031344 175 0.043
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.043
cell part morphogenesis GO:0032990 123 0.043
Fly
brain development GO:0007420 247 0.042
Rat Fly
regulation of protein localization GO:0032880 81 0.042
Human
positive regulation of cellular protein metabolic process GO:0032270 167 0.041
Human Rat Fly
regulation of neuron projection development GO:0010975 161 0.041
anatomical structure morphogenesis GO:0009653 298 0.041
Human Mouse Rat Worm Fly
positive regulation of protein phosphorylation GO:0001934 135 0.041
Human Rat Fly
cellular response to hormone stimulus GO:0032870 247 0.040
Rat
response to hypoxia GO:0001666 231 0.040
positive regulation of signal transduction GO:0009967 175 0.040
Human Rat Fly
negative regulation of cellular protein metabolic process GO:0032269 106 0.040
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.040
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.039
Rat Worm
positive regulation of cell proliferation GO:0008284 249 0.039
Human Rat
regulation of signal transduction GO:0009966 318 0.039
Human Rat Fly
regulation of cell morphogenesis GO:0022604 77 0.039
Worm
reproduction GO:0000003 245 0.039
Mouse Rat Worm
dephosphorylation GO:0016311 98 0.038
regulation of cell migration GO:0030334 128 0.038
negative regulation of signaling GO:0023057 157 0.038
Human
positive regulation of locomotion GO:0040017 102 0.038
positive regulation of cell communication GO:0010647 271 0.037
Human Rat Fly
embryonic skeletal system morphogenesis GO:0048704 3 0.037
Mouse
reproductive process GO:0022414 372 0.037
cellular component morphogenesis GO:0032989 155 0.037
Human Worm Fly
positive regulation of protein metabolic process GO:0051247 178 0.036
Human Rat Worm Fly
negative regulation of cell proliferation GO:0008285 119 0.036
Mouse Rat
regulation of proteolysis GO:0030162 66 0.036
negative regulation of cell differentiation GO:0045596 99 0.036
cell morphogenesis GO:0000902 142 0.035
Human Worm Fly
epithelium development GO:0060429 96 0.035
negative regulation of transport GO:0051051 136 0.035
regulation of cellular localization GO:0060341 263 0.035
Human
negative regulation of organ growth GO:0046621 3 0.035
Rat
neurological system process GO:0050877 219 0.035
oxoacid metabolic process GO:0043436 290 0.034
response to inorganic substance GO:0010035 377 0.034
head development GO:0060322 247 0.033
Rat Fly
muscle contraction GO:0006936 88 0.033
negative regulation of programmed cell death GO:0043069 183 0.033
Human Mouse
single organism organelle organization GO:1902589 180 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.032
proteolysis GO:0006508 175 0.032
regulation of mapk cascade GO:0043408 116 0.032
Human
aromatic compound catabolic process GO:0019439 168 0.032
cellular response to steroid hormone stimulus GO:0071383 93 0.031
Rat
response to transforming growth factor beta GO:0071559 46 0.031
negative regulation of multicellular organismal process GO:0051241 203 0.031
Mouse Rat
positive regulation of secretion GO:0051047 140 0.031
muscle structure development GO:0061061 87 0.031
Rat
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.031
Rat
peptidyl tyrosine phosphorylation GO:0018108 72 0.031
synaptic growth at neuromuscular junction GO:0051124 1 0.030
organic acid metabolic process GO:0006082 292 0.030
synaptic transmission GO:0007268 235 0.030
response to ketone GO:1901654 182 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.030
response to transition metal nanoparticle GO:1990267 122 0.030
activation of protein kinase activity GO:0032147 47 0.030
Human
positive regulation of nervous system development GO:0051962 178 0.030
cellular response to organic cyclic compound GO:0071407 202 0.030
Rat
gastrulation GO:0007369 2 0.029
bmp signaling pathway GO:0030509 4 0.029
Fly
response to monosaccharide GO:0034284 159 0.029
Rat
positive regulation of transferase activity GO:0051347 81 0.029
Human
protein transport GO:0015031 132 0.029
Human
single organism reproductive process GO:0044702 297 0.029
embryonic cranial skeleton morphogenesis GO:0048701 2 0.029
Mouse
response to wounding GO:0009611 254 0.029
Rat
regulation of system process GO:0044057 208 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
circulatory system process GO:0003013 183 0.029
dendrite development GO:0016358 72 0.028
positive regulation of biomineral tissue development GO:0070169 4 0.028
sensory organ development GO:0007423 74 0.028
Mouse
gamete generation GO:0007276 124 0.028
Mouse
axonogenesis GO:0007409 71 0.028
Fly
negative regulation of protein metabolic process GO:0051248 114 0.028
response to metal ion GO:0010038 253 0.028
cellular protein complex assembly GO:0043623 44 0.028
Rat
carbohydrate metabolic process GO:0005975 130 0.028
transforming growth factor beta3 production GO:0032907 2 0.028
reactive oxygen species metabolic process GO:0072593 37 0.028
single organism catabolic process GO:0044712 283 0.028
immune response GO:0006955 104 0.027
Worm
peptidyl serine phosphorylation GO:0018105 33 0.027
Human
nitrogen compound transport GO:0071705 229 0.027
protein heterooligomerization GO:0051291 89 0.027
Rat
axon development GO:0061564 96 0.027
Fly
positive regulation of neuron differentiation GO:0045666 126 0.027
response to lipopolysaccharide GO:0032496 191 0.027
cellular lipid metabolic process GO:0044255 208 0.027
positive regulation of cellular component movement GO:0051272 102 0.027
Human
response to nutrient GO:0007584 248 0.027
Rat
single organism biosynthetic process GO:0044711 342 0.026
cell junction organization GO:0034330 21 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
actin filament based movement GO:0030048 16 0.026
cellular catabolic process GO:0044248 295 0.026
Fly
multicellular organism reproduction GO:0032504 233 0.026
Mouse Rat
response to fatty acid GO:0070542 65 0.026
response to cytokine GO:0034097 215 0.026
inorganic cation transmembrane transport GO:0098662 202 0.026
regulation of secretion GO:0051046 224 0.026
catabolic process GO:0009056 351 0.026
Worm Fly
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
regulation of membrane potential GO:0042391 110 0.025
reproductive structure development GO:0048608 128 0.025
Mouse Rat
cell cell signaling GO:0007267 335 0.025
lipid biosynthetic process GO:0008610 128 0.025
cellular macromolecule localization GO:0070727 122 0.025
Human Worm
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.025
positive regulation of transport GO:0051050 245 0.025
Human
negative regulation of cardiac muscle tissue development GO:0055026 3 0.025
Rat
regulation of synaptic transmission GO:0050804 141 0.025
protein complex biogenesis GO:0070271 263 0.025
Rat
blood vessel development GO:0001568 69 0.025
Mouse Rat
protein localization GO:0008104 191 0.024
Human Worm
cell adhesion GO:0007155 110 0.024
Worm
activation of cysteine type endopeptidase activity GO:0097202 4 0.024
negative regulation of biosynthetic process GO:0009890 168 0.024
response to carbohydrate GO:0009743 183 0.024
Rat
cellular response to lipid GO:0071396 201 0.024
Rat
response to hexose GO:0009746 144 0.024
Rat
negative regulation of transcription dna templated GO:0045892 116 0.024
ion homeostasis GO:0050801 212 0.024
response to estradiol GO:0032355 164 0.024
positive regulation of developmental process GO:0051094 283 0.024
Rat Worm
response to glucocorticoid GO:0051384 223 0.023
Rat
response to oxygen levels GO:0070482 265 0.023
negative regulation of cell death GO:0060548 229 0.023
Human Mouse
regulation of actin filament based process GO:0032970 42 0.023
blood circulation GO:0008015 183 0.023
positive regulation of neuron projection development GO:0010976 99 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
negative regulation of nervous system development GO:0051961 79 0.023
organophosphate metabolic process GO:0019637 370 0.023
cell projection morphogenesis GO:0048858 123 0.023
Fly
myeloid leukocyte activation GO:0002274 36 0.023
negative regulation of signal transduction GO:0009968 83 0.022
Human
metal ion transport GO:0030001 289 0.022
negative regulation of phosphate metabolic process GO:0045936 80 0.022
dendrite morphogenesis GO:0048813 43 0.022
cell cycle process GO:0022402 57 0.022
vesicle mediated transport GO:0016192 181 0.022
Rat
cellular macromolecular complex assembly GO:0034622 58 0.022
Rat
regulation of growth GO:0040008 105 0.022
Human Rat Worm
cellular response to abiotic stimulus GO:0071214 85 0.022
behavior GO:0007610 205 0.022
negative regulation of developmental process GO:0051093 125 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
cellular response to stress GO:0033554 269 0.022
reactive nitrogen species metabolic process GO:2001057 1 0.022
positive regulation of signaling GO:0023056 270 0.022
Human Rat Fly
regulation of catabolic process GO:0009894 113 0.022
Worm Fly
regulation of establishment of protein localization GO:0070201 69 0.022
Human
protein targeting GO:0006605 61 0.021
Human
cellular response to peptide hormone stimulus GO:0071375 120 0.021
rhythmic process GO:0048511 156 0.021
Rat
regulation of transferase activity GO:0051338 123 0.021
Human
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.021
transmission of nerve impulse GO:0019226 42 0.021
muscle cell apoptotic process GO:0010657 30 0.021
regulation of dendrite development GO:0050773 59 0.021
regulation of cell adhesion GO:0030155 52 0.021
Worm
heart morphogenesis GO:0003007 3 0.021
regulation of cell growth GO:0001558 85 0.021
Human
response to glucose GO:0009749 136 0.021
Rat
establishment of protein localization GO:0045184 141 0.020
Human
negative regulation of muscle cell apoptotic process GO:0010656 21 0.020
regulation of lipid metabolic process GO:0019216 68 0.020
regulation of cellular component biogenesis GO:0044087 86 0.020
Mouse
action potential GO:0001508 54 0.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
Worm
cellular response to organonitrogen compound GO:0071417 197 0.020
chemical homeostasis GO:0048878 292 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
negative regulation of cellular component organization GO:0051129 83 0.020
positive regulation of skeletal muscle tissue regeneration GO:0043415 1 0.020
Rat
phospholipid metabolic process GO:0006644 61 0.020
vasculogenesis GO:0001570 3 0.019
Rat
glial cell differentiation GO:0010001 65 0.019
regulation of response to stress GO:0080134 126 0.019
Rat
protein oligomerization GO:0051259 191 0.019
Rat
positive regulation of mapk cascade GO:0043410 92 0.019
Human
response to oxidative stress GO:0006979 186 0.019
embryonic pattern specification GO:0009880 1 0.019
eye development GO:0001654 50 0.018
Mouse
cardiac ventricle development GO:0003231 1 0.018
regulation of immune system process GO:0002682 123 0.018
anatomical structure formation involved in morphogenesis GO:0048646 83 0.018
Mouse
cell cell junction organization GO:0045216 20 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.018
regulation of map kinase activity GO:0043405 53 0.018
Human
positive regulation of immune system process GO:0002684 90 0.018
cell fate determination GO:0001709 2 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
Human Mouse
negative regulation of response to stimulus GO:0048585 155 0.018
Human
eye morphogenesis GO:0048592 4 0.018
regulation of endocytosis GO:0030100 42 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
Mouse
multicellular organismal signaling GO:0035637 44 0.018
regulation of blood circulation GO:1903522 110 0.018
anterior posterior pattern specification GO:0009952 1 0.017
Mouse
receptor mediated endocytosis GO:0006898 42 0.017
Rat
developmental growth GO:0048589 100 0.017
Rat Worm
intracellular protein transport GO:0006886 79 0.017
Human
cell cycle checkpoint GO:0000075 2 0.017
single organism cellular localization GO:1902580 102 0.017
Human
lipid transport GO:0006869 61 0.017
positive regulation of cell development GO:0010720 176 0.017
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.017
Rat
regulation of secretion by cell GO:1903530 208 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.017
cellular homeostasis GO:0019725 252 0.016
regulation of cell cycle process GO:0010564 31 0.016
positive regulation of protein localization to nucleus GO:1900182 15 0.016
Human
secretion by cell GO:0032940 248 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
Mouse Rat
urogenital system development GO:0001655 78 0.016
Mouse Rat
positive regulation of catabolic process GO:0009896 78 0.016
Worm
negative regulation of catalytic activity GO:0043086 103 0.016
axis specification GO:0009798 4 0.016
negative regulation of protein phosphorylation GO:0001933 44 0.016
muscle system process GO:0003012 115 0.016
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.016
peptidyl tyrosine modification GO:0018212 72 0.016
camera type eye development GO:0043010 48 0.016
Mouse
regulation of ion transport GO:0043269 245 0.016
gliogenesis GO:0042063 93 0.016
regulation of anatomical structure size GO:0090066 135 0.016
regulation of vesicle mediated transport GO:0060627 81 0.016
positive regulation of bone mineralization GO:0030501 4 0.016
mesenchymal cell proliferation GO:0010463 4 0.016
ion transmembrane transport GO:0034220 365 0.016
response to mechanical stimulus GO:0009612 134 0.015
Rat
response to acid chemical GO:0001101 222 0.015
embryo implantation GO:0007566 15 0.015
mesoderm development GO:0007498 2 0.015
nuclear transport GO:0051169 49 0.015
Human
cardiovascular system development GO:0072358 134 0.015
Mouse Rat
protein modification by small protein conjugation GO:0032446 31 0.015
Human
positive regulation of kinase activity GO:0033674 77 0.015
Human
cytoplasmic transport GO:0016482 115 0.015
Human
response to external biotic stimulus GO:0043207 221 0.015
Worm
positive regulation of tolerance induction GO:0002645 1 0.015
response to purine containing compound GO:0014074 126 0.015
peptidyl serine modification GO:0018209 34 0.015
Human
purine nucleoside metabolic process GO:0042278 169 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
muscle cell proliferation GO:0033002 84 0.015
Rat
wound healing GO:0042060 122 0.015
Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.015
tube development GO:0035295 89 0.015
sex differentiation GO:0007548 113 0.015
Mouse Rat Worm
gland development GO:0048732 155 0.014
Mouse
cell cycle GO:0007049 101 0.014
Fly
response to hydrogen peroxide GO:0042542 89 0.014
response to amino acid GO:0043200 75 0.014
ras protein signal transduction GO:0007265 29 0.014
cellular response to insulin stimulus GO:0032869 81 0.014
regulation of muscle cell apoptotic process GO:0010660 26 0.014
multi multicellular organism process GO:0044706 138 0.014
response to peptide hormone GO:0043434 278 0.014
regulation of organelle organization GO:0033043 80 0.014
homeostatic process GO:0042592 331 0.014
regulation of protein serine threonine kinase activity GO:0071900 64 0.014
Human
glycerophospholipid metabolic process GO:0006650 47 0.014
single organism intracellular transport GO:1902582 166 0.014
Human
response to temperature stimulus GO:0009266 94 0.014
heterocycle catabolic process GO:0046700 167 0.014
response to ethanol GO:0045471 162 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
dna replication GO:0006260 37 0.014
heart development GO:0007507 72 0.014
Mouse Rat
synapse organization GO:0050808 46 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
organophosphate catabolic process GO:0046434 148 0.014
protein dephosphorylation GO:0006470 38 0.014
organophosphate biosynthetic process GO:0090407 143 0.013
pallium development GO:0021543 42 0.013
Rat
multicellular organism growth GO:0035264 1 0.013
Worm
response to reactive oxygen species GO:0000302 120 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
negative regulation of phosphorylation GO:0042326 57 0.013
negative regulation of cardiac muscle cell proliferation GO:0060044 2 0.013
Rat
positive regulation of map kinase activity GO:0043406 46 0.013
Human
positive regulation of apoptotic process GO:0043065 154 0.013
Human
retinal ganglion cell axon guidance GO:0031290 1 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
intracellular transport GO:0046907 185 0.013
Human
actin mediated cell contraction GO:0070252 12 0.013
regulation of muscle system process GO:0090257 79 0.013
dna metabolic process GO:0006259 96 0.013
spindle organization GO:0007051 2 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
cellular cation homeostasis GO:0030003 180 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
response to growth factor GO:0070848 189 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
epiboly involved in wound healing GO:0090505 2 0.013
developmental process involved in reproduction GO:0003006 159 0.013
Mouse Rat Worm
negative regulation of rna biosynthetic process GO:1902679 118 0.013
regulation of response to wounding GO:1903034 69 0.013
Rat
organ formation GO:0048645 3 0.013
cell activation GO:0001775 97 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
Human
tissue morphogenesis GO:0048729 22 0.012
organic hydroxy compound transport GO:0015850 77 0.012
palate development GO:0060021 2 0.012
Mouse
secretion GO:0046903 307 0.012
signal transduction involved in regulation of gene expression GO:0023019 4 0.012
negative regulation of protein maturation GO:1903318 47 0.012
nuclear import GO:0051170 35 0.012
Human
cellular response to reactive oxygen species GO:0034614 55 0.012
endothelial cell differentiation GO:0045446 9 0.012
nucleotide metabolic process GO:0009117 279 0.012
regeneration GO:0031099 163 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
ovulation cycle GO:0042698 67 0.012
Rat
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
defense response GO:0006952 194 0.012
Worm
regulation of dendrite morphogenesis GO:0048814 33 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.012
embryo development GO:0009790 49 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
response to peptide GO:1901652 292 0.012
positive regulation of intracellular protein transport GO:0090316 20 0.012
Human
potassium ion transport GO:0006813 97 0.012
cellular response to peptide GO:1901653 133 0.012
actin cytoskeleton organization GO:0030036 73 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
heart contraction GO:0060047 57 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
neural crest cell differentiation GO:0014033 2 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.011

Tgfbr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.088
cancer DOID:162 0 0.071
organ system cancer DOID:0050686 0 0.071
nervous system disease DOID:863 0 0.043
disease of anatomical entity DOID:7 0 0.043
gastrointestinal system cancer DOID:3119 0 0.039
sensory system disease DOID:0050155 0 0.018
retinal disease DOID:5679 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
disease of metabolism DOID:0014667 0 0.012
central nervous system disease DOID:331 0 0.012