Rattus norvegicus

113 known processes

Tgm2

transglutaminase 2, C polypeptide

(Aliases: TgaseII)

Tgm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood coagulation GO:0007596 26 0.306
Rat
protein phosphorylation GO:0006468 345 0.237
cellular response to endogenous stimulus GO:0071495 377 0.214
response to growth factor GO:0070848 189 0.186
regulation of phosphorus metabolic process GO:0051174 349 0.185
regulation of phosphate metabolic process GO:0019220 349 0.175
oxoacid metabolic process GO:0043436 290 0.168
vesicle mediated transport GO:0016192 181 0.166
Human
positive regulation of phosphate metabolic process GO:0045937 262 0.164
positive regulation of phosphorus metabolic process GO:0010562 262 0.156
actin filament based process GO:0030029 86 0.148
carbohydrate derivative metabolic process GO:1901135 346 0.143
regulation of cellular ketone metabolic process GO:0010565 27 0.115
protein complex assembly GO:0006461 263 0.113
cellular amino acid metabolic process GO:0006520 107 0.108
tissue development GO:0009888 252 0.106
regulation of response to stress GO:0080134 126 0.106
programmed cell death GO:0012501 392 0.106
amine metabolic process GO:0009308 38 0.103
cell adhesion GO:0007155 110 0.102
cellular ketone metabolic process GO:0042180 51 0.102
organic acid metabolic process GO:0006082 292 0.102
cellular response to growth factor stimulus GO:0071363 162 0.100
cellular amine metabolic process GO:0044106 38 0.098
organic substance catabolic process GO:1901575 316 0.095
regulation of phosphorylation GO:0042325 248 0.095
response to hypoxia GO:0001666 231 0.095
glycosyl compound metabolic process GO:1901657 182 0.086
regulation of cellular amino acid metabolic process GO:0006521 2 0.086
regulation of apoptotic process GO:0042981 335 0.083
regulation of cellular component organization GO:0051128 368 0.083
protein complex subunit organization GO:0071822 302 0.082
defense response GO:0006952 194 0.082
response to oxygen levels GO:0070482 265 0.082
single organism biosynthetic process GO:0044711 342 0.080
apoptotic process GO:0006915 381 0.079
positive regulation of cellular component organization GO:0051130 200 0.078
regulation of cellular amine metabolic process GO:0033238 8 0.077
response to ionizing radiation GO:0010212 59 0.074
peptidyl tyrosine phosphorylation GO:0018108 72 0.074
response to nutrient GO:0007584 248 0.073
regulation of endocytosis GO:0030100 42 0.073
response to decreased oxygen levels GO:0036293 237 0.071
nucleotide metabolic process GO:0009117 279 0.071
regulation of cell migration GO:0030334 128 0.069
secretion GO:0046903 307 0.069
negative regulation of cellular metabolic process GO:0031324 281 0.068
cellular catabolic process GO:0044248 295 0.068
regulation of protein metabolic process GO:0051246 289 0.067
purine nucleotide metabolic process GO:0006163 229 0.066
aging GO:0007568 241 0.065
response to inorganic substance GO:0010035 377 0.065
positive regulation of response to stimulus GO:0048584 285 0.063
inflammatory response GO:0006954 150 0.063
ribonucleotide metabolic process GO:0009259 231 0.063
rna biosynthetic process GO:0032774 380 0.062
purine nucleoside metabolic process GO:0042278 169 0.060
regulation of vesicle mediated transport GO:0060627 81 0.060
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.059
regulation of locomotion GO:0040012 148 0.059
macromolecular complex assembly GO:0065003 273 0.059
transcription dna templated GO:0006351 377 0.058
cellular response to hormone stimulus GO:0032870 247 0.058
purine containing compound metabolic process GO:0072521 253 0.057
positive regulation of protein phosphorylation GO:0001934 135 0.057
carboxylic acid metabolic process GO:0019752 289 0.056
positive regulation of signaling GO:0023056 270 0.056
catabolic process GO:0009056 351 0.056
rna metabolic process GO:0016070 406 0.055
positive regulation of cellular protein metabolic process GO:0032270 167 0.055
endocytosis GO:0006897 84 0.053
Human
regulation of cellular protein metabolic process GO:0032268 267 0.052
positive regulation of protein modification process GO:0031401 142 0.052
regulation of protein phosphorylation GO:0001932 183 0.051
epithelium development GO:0060429 96 0.051
positive regulation of cellular amine metabolic process GO:0033240 3 0.051
negative regulation of metabolic process GO:0009892 331 0.050
single organism organelle organization GO:1902589 180 0.050
nucleoside monophosphate metabolic process GO:0009123 93 0.049
response to wounding GO:0009611 254 0.049
peptidyl amino acid modification GO:0018193 126 0.048
peptidyl tyrosine modification GO:0018212 72 0.047
nucleoside phosphate metabolic process GO:0006753 283 0.047
positive regulation of cell proliferation GO:0008284 249 0.046
regulation of secretion GO:0051046 224 0.046
ribose phosphate metabolic process GO:0019693 235 0.046
positive regulation of developmental process GO:0051094 283 0.045
nucleic acid templated transcription GO:0097659 379 0.044
cellular response to lipid GO:0071396 201 0.044
regulation of protein modification process GO:0031399 194 0.044
response to nutrient levels GO:0031667 370 0.044
regulation of catalytic activity GO:0050790 304 0.043
locomotion GO:0040011 237 0.043
intracellular signal transduction GO:0035556 314 0.043
cytoskeleton organization GO:0007010 111 0.043
protein complex biogenesis GO:0070271 263 0.043
response to extracellular stimulus GO:0009991 380 0.043
atp metabolic process GO:0046034 72 0.041
homeostatic process GO:0042592 331 0.041
cellular component biogenesis GO:0044085 368 0.041
reproductive process GO:0022414 372 0.041
negative regulation of cell death GO:0060548 229 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
regulation of signal transduction GO:0009966 318 0.040
response to mechanical stimulus GO:0009612 134 0.039
chemical homeostasis GO:0048878 292 0.039
negative regulation of apoptotic process GO:0043066 181 0.039
actin cytoskeleton organization GO:0030036 73 0.039
purine ribonucleoside metabolic process GO:0046128 168 0.038
biological adhesion GO:0022610 110 0.038
regulation of system process GO:0044057 208 0.038
purine nucleoside monophosphate metabolic process GO:0009126 84 0.038
cell projection organization GO:0030030 302 0.038
coagulation GO:0050817 28 0.037
Rat
ribonucleoside monophosphate metabolic process GO:0009161 88 0.037
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.037
positive regulation of protein metabolic process GO:0051247 178 0.036
neuron differentiation GO:0030182 368 0.036
positive regulation of phosphorylation GO:0042327 177 0.036
cellular response to stress GO:0033554 269 0.036
single organism catabolic process GO:0044712 283 0.035
regulation of cellular localization GO:0060341 263 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.035
regulation of body fluid levels GO:0050878 90 0.035
Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.035
protein localization GO:0008104 191 0.035
organonitrogen compound catabolic process GO:1901565 179 0.034
regulation of cell projection organization GO:0031344 175 0.034
immune response GO:0006955 104 0.034
regulation of rna metabolic process GO:0051252 391 0.034
epithelial cell differentiation GO:0030855 71 0.034
cellular component assembly GO:0022607 360 0.034
proteolysis GO:0006508 175 0.034
purine containing compound catabolic process GO:0072523 138 0.033
striated muscle tissue development GO:0014706 58 0.033
ribonucleoside metabolic process GO:0009119 174 0.033
cellular component movement GO:0006928 248 0.033
regulation of cell motility GO:2000145 131 0.033
regulation of anatomical structure morphogenesis GO:0022603 141 0.033
organophosphate metabolic process GO:0019637 370 0.033
localization of cell GO:0051674 202 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
regulation of vasculature development GO:1901342 44 0.032
neuron projection development GO:0031175 273 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
leukocyte differentiation GO:0002521 30 0.031
muscle structure development GO:0061061 87 0.030
positive regulation of cell differentiation GO:0045597 217 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
negative regulation of rna metabolic process GO:0051253 123 0.030
positive regulation of signal transduction GO:0009967 175 0.029
organelle organization GO:0006996 266 0.029
positive regulation of cell communication GO:0010647 271 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
regulation of cellular component movement GO:0051270 150 0.029
response to radiation GO:0009314 137 0.029
calcium ion transport GO:0006816 131 0.029
negative regulation of multicellular organismal process GO:0051241 203 0.029
regulation of cell development GO:0060284 263 0.028
cellular chemical homeostasis GO:0055082 247 0.028
growth GO:0040007 165 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
response to bacterium GO:0009617 200 0.028
positive regulation of endocytosis GO:0045807 28 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.028
response to cytokine GO:0034097 215 0.027
cellular response to external stimulus GO:0071496 118 0.027
regulation of immune system process GO:0002682 123 0.027
ribonucleotide catabolic process GO:0009261 136 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
immune system process GO:0002376 204 0.027
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.027
regulation of mapk cascade GO:0043408 116 0.027
protein oligomerization GO:0051259 191 0.026
lipid metabolic process GO:0006629 283 0.026
response to corticosteroid GO:0031960 235 0.026
positive regulation of transport GO:0051050 245 0.026
regulation of programmed cell death GO:0043067 341 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
response to monosaccharide GO:0034284 159 0.025
regulation of secretion by cell GO:1903530 208 0.025
response to metal ion GO:0010038 253 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.025
regulation of molecular function GO:0065009 398 0.025
regulation of transcription dna templated GO:0006355 374 0.024
response to oxidative stress GO:0006979 186 0.024
muscle tissue development GO:0060537 58 0.024
cellular response to organic cyclic compound GO:0071407 202 0.024
nucleoside metabolic process GO:0009116 179 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
carbohydrate derivative biosynthetic process GO:1901137 124 0.024
positive regulation of cell death GO:0010942 184 0.024
regulation of neurogenesis GO:0050767 247 0.024
pinocytosis GO:0006907 1 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
single organism reproductive process GO:0044702 297 0.024
cell migration GO:0016477 197 0.024
purine nucleoside monophosphate catabolic process GO:0009128 55 0.024
positive regulation of cell projection organization GO:0031346 111 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
anatomical structure morphogenesis GO:0009653 298 0.023
ribonucleoside triphosphate metabolic process GO:0009199 141 0.023
hepaticobiliary system development GO:0061008 90 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
regulation of nucleotide metabolic process GO:0006140 117 0.023
nucleoside phosphate catabolic process GO:1901292 140 0.023
establishment of protein localization GO:0045184 141 0.023
positive regulation of biosynthetic process GO:0009891 319 0.022
organ regeneration GO:0031100 101 0.022
regulation of purine nucleotide catabolic process GO:0033121 65 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.022
cell motility GO:0048870 202 0.022
head development GO:0060322 247 0.022
nucleoside catabolic process GO:0009164 126 0.022
regulation of reactive oxygen species metabolic process GO:2000377 26 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
cellular response to abiotic stimulus GO:0071214 85 0.021
regulation of cell differentiation GO:0045595 320 0.021
cell morphogenesis GO:0000902 142 0.021
regulation of cell proliferation GO:0042127 359 0.021
reactive oxygen species metabolic process GO:0072593 37 0.021
brain development GO:0007420 247 0.021
regulation of nervous system development GO:0051960 264 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
secretion by cell GO:0032940 248 0.020
immunoglobulin mediated immune response GO:0016064 4 0.020
protein transport GO:0015031 132 0.020
purine nucleoside triphosphate catabolic process GO:0009146 122 0.020
response to vitamin GO:0033273 131 0.020
reproduction GO:0000003 245 0.019
response to carbohydrate GO:0009743 183 0.019
rhythmic process GO:0048511 156 0.019
response to glucocorticoid GO:0051384 223 0.019
leukocyte cell cell adhesion GO:0007159 4 0.019
dephosphorylation GO:0016311 98 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
response to interleukin 1 GO:0070555 55 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
nucleotide catabolic process GO:0009166 139 0.019
single organism membrane organization GO:0044802 74 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
circulatory system development GO:0072359 134 0.018
response to hexose GO:0009746 144 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
axis specification GO:0009798 4 0.018
ion homeostasis GO:0050801 212 0.018
response to reactive oxygen species GO:0000302 120 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
positive regulation of molecular function GO:0044093 230 0.018
positive regulation of cell development GO:0010720 176 0.018
response to activity GO:0014823 73 0.018
central nervous system development GO:0007417 311 0.017
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
negative regulation of cell differentiation GO:0045596 99 0.017
positive regulation of gene expression GO:0010628 244 0.017
multicellular organismal signaling GO:0035637 44 0.017
hemostasis GO:0007599 26 0.017
Rat
multicellular organismal reproductive process GO:0048609 233 0.017
response to biotic stimulus GO:0009607 226 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
regulation of homeostatic process GO:0032844 101 0.017
cellular cation homeostasis GO:0030003 180 0.017
ion transmembrane transport GO:0034220 365 0.017
response to glucose GO:0009749 136 0.017
negative regulation of transport GO:0051051 136 0.017
cellular component morphogenesis GO:0032989 155 0.017
blood circulation GO:0008015 183 0.017
cell matrix adhesion GO:0007160 19 0.017
ras protein signal transduction GO:0007265 29 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
intracellular transport GO:0046907 185 0.016
cell activation GO:0001775 97 0.016
wound healing GO:0042060 122 0.016
Rat
response to molecule of bacterial origin GO:0002237 194 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
regulation of transferase activity GO:0051338 123 0.016
multicellular organism reproduction GO:0032504 233 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
organophosphate catabolic process GO:0046434 148 0.016
immune system development GO:0002520 41 0.015
immune effector process GO:0002252 53 0.015
leukocyte migration GO:0050900 38 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
platelet aggregation GO:0070527 4 0.015
reactive nitrogen species metabolic process GO:2001057 1 0.015
aromatic compound catabolic process GO:0019439 168 0.015
response to external biotic stimulus GO:0043207 221 0.015
membrane organization GO:0061024 94 0.015
regulation of catabolic process GO:0009894 113 0.015
atp catabolic process GO:0006200 54 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
positive regulation of locomotion GO:0040017 102 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
cell cell signaling GO:0007267 335 0.014
ribonucleoside monophosphate catabolic process GO:0009158 55 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 5 0.014
nucleoside monophosphate catabolic process GO:0009125 56 0.014
positive regulation of angiogenesis GO:0045766 28 0.014
response to estrogen GO:0043627 232 0.014
response to lipopolysaccharide GO:0032496 191 0.014
single organism cellular localization GO:1902580 102 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
cell cycle process GO:0022402 57 0.014
response to peptide GO:1901652 292 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
protein heterooligomerization GO:0051291 89 0.013
positive regulation of nervous system development GO:0051962 178 0.013
divalent metal ion transport GO:0070838 132 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
protein catabolic process GO:0030163 30 0.013
regulation of cellular response to growth factor stimulus GO:0090287 15 0.013
neuronal action potential GO:0019228 35 0.013
multi organism reproductive process GO:0044703 262 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.013
single organism cell adhesion GO:0098602 46 0.013
anion transport GO:0006820 178 0.012
cation homeostasis GO:0055080 195 0.012
multicellular organism growth GO:0035264 1 0.012
blood vessel morphogenesis GO:0048514 58 0.012
b cell mediated immunity GO:0019724 4 0.012
organelle localization GO:0051640 55 0.012
transmembrane transport GO:0055085 412 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
cellular response to lipopolysaccharide GO:0071222 55 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
macromolecule localization GO:0033036 252 0.012
regulation of protein kinase activity GO:0045859 105 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
regeneration GO:0031099 163 0.012
regulation of muscle system process GO:0090257 79 0.012
cellular macromolecule localization GO:0070727 122 0.012
negative regulation of cell development GO:0010721 82 0.012
leukocyte activation GO:0045321 76 0.012
cell part morphogenesis GO:0032990 123 0.012
regulation of membrane potential GO:0042391 110 0.012
positive regulation of biomineral tissue development GO:0070169 4 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
gamete generation GO:0007276 124 0.012
single organism intracellular transport GO:1902582 166 0.012
response to hydrogen peroxide GO:0042542 89 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
cellular homeostasis GO:0019725 252 0.011
regulation of map kinase activity GO:0043405 53 0.011
cellular protein catabolic process GO:0044257 19 0.011
negative regulation of cell communication GO:0010648 158 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
response to ketone GO:1901654 182 0.011
negative regulation of molecular function GO:0044092 133 0.011
hormone secretion GO:0046879 115 0.011
leukocyte mediated immunity GO:0002443 28 0.011
cellular protein complex assembly GO:0043623 44 0.011
heterocycle catabolic process GO:0046700 167 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
calcium ion homeostasis GO:0055074 162 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
lipid biosynthetic process GO:0008610 128 0.011
metal ion homeostasis GO:0055065 186 0.011
neuron development GO:0048666 286 0.011
positive regulation of defense response GO:0031349 37 0.011
purine nucleoside biosynthetic process GO:0042451 21 0.011
development of primary sexual characteristics GO:0045137 107 0.011
embryonic pattern specification GO:0009880 1 0.010
negative regulation of secretion GO:0051048 82 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.010
renal system development GO:0072001 67 0.010
spindle organization GO:0007051 2 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
muscle contraction GO:0006936 88 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
transmission of nerve impulse GO:0019226 42 0.010
positive regulation of cell migration GO:0030335 96 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
muscle system process GO:0003012 115 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
tissue regeneration GO:0042246 36 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
hemopoiesis GO:0030097 34 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
cellular protein localization GO:0034613 122 0.010
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.010

Tgm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 0 0.030
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.017
sensory system disease DOID:0050155 0 0.012
muscle tissue disease DOID:66 0 0.011
musculoskeletal system disease DOID:17 0 0.011
intrinsic cardiomyopathy DOID:0060036 0 0.011
dilated cardiomyopathy DOID:12930 0 0.011
muscular disease DOID:0080000 0 0.011
cardiomyopathy DOID:0050700 0 0.011
myopathy DOID:423 0 0.011
heart disease DOID:114 0 0.011