Rattus norvegicus

7 known processes

Thop1

thimet oligopeptidase 1

(Aliases: EP24.15,MGC93105)

Thop1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.331
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.294
nucleic acid templated transcription GO:0097659 379 0.235
aromatic compound catabolic process GO:0019439 168 0.232
organophosphate catabolic process GO:0046434 148 0.217
heterocycle catabolic process GO:0046700 167 0.200
transcription dna templated GO:0006351 377 0.196
regulation of rna biosynthetic process GO:2001141 381 0.196
protein localization GO:0008104 191 0.187
macromolecule localization GO:0033036 252 0.182
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.181
rna biosynthetic process GO:0032774 380 0.169
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.168
purine nucleotide catabolic process GO:0006195 136 0.164
positive regulation of transcription dna templated GO:0045893 197 0.143
nucleotide metabolic process GO:0009117 279 0.129
carbohydrate derivative metabolic process GO:1901135 346 0.129
cell cell signaling GO:0007267 335 0.117
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.108
organic substance catabolic process GO:1901575 316 0.103
reproductive system development GO:0061458 128 0.103
response to extracellular stimulus GO:0009991 380 0.103
regulation of apoptotic process GO:0042981 335 0.102
reproductive process GO:0022414 372 0.096
positive regulation of gene expression GO:0010628 244 0.093
nucleobase containing small molecule metabolic process GO:0055086 316 0.092
regulation of nucleic acid templated transcription GO:1903506 380 0.091
cellular catabolic process GO:0044248 295 0.090
nucleoside phosphate metabolic process GO:0006753 283 0.088
nucleoside metabolic process GO:0009116 179 0.086
nucleotide catabolic process GO:0009166 139 0.085
transcription from rna polymerase ii promoter GO:0006366 252 0.085
developmental process involved in reproduction GO:0003006 159 0.083
protein complex biogenesis GO:0070271 263 0.081
response to nutrient GO:0007584 248 0.081
positive regulation of biosynthetic process GO:0009891 319 0.081
regulation of rna metabolic process GO:0051252 391 0.079
ribonucleotide metabolic process GO:0009259 231 0.079
response to peptide hormone GO:0043434 278 0.077
gonad development GO:0008406 104 0.074
anatomical structure morphogenesis GO:0009653 298 0.074
regulation of cell proliferation GO:0042127 359 0.072
reproductive structure development GO:0048608 128 0.072
regulation of protein metabolic process GO:0051246 289 0.071
synaptic transmission GO:0007268 235 0.070
organophosphate metabolic process GO:0019637 370 0.070
cellular protein localization GO:0034613 122 0.069
vesicle mediated transport GO:0016192 181 0.068
reproduction GO:0000003 245 0.067
regulation of transcription dna templated GO:0006355 374 0.067
regulation of phosphorus metabolic process GO:0051174 349 0.066
catabolic process GO:0009056 351 0.065
positive regulation of rna biosynthetic process GO:1902680 197 0.064
purine containing compound metabolic process GO:0072521 253 0.063
positive regulation of cellular biosynthetic process GO:0031328 295 0.063
multi organism reproductive process GO:0044703 262 0.062
establishment of protein localization GO:0045184 141 0.057
regulation of phosphorylation GO:0042325 248 0.056
protein complex subunit organization GO:0071822 302 0.056
positive regulation of phosphate metabolic process GO:0045937 262 0.056
brain development GO:0007420 247 0.056
single organism reproductive process GO:0044702 297 0.056
protein targeting GO:0006605 61 0.055
nucleobase containing compound catabolic process GO:0034655 152 0.054
macromolecular complex assembly GO:0065003 273 0.054
positive regulation of developmental process GO:0051094 283 0.054
negative regulation of gene expression GO:0010629 199 0.054
programmed cell death GO:0012501 392 0.054
cellular macromolecule localization GO:0070727 122 0.053
single organism cellular localization GO:1902580 102 0.052
head development GO:0060322 247 0.051
regulation of cellular localization GO:0060341 263 0.051
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.051
purine ribonucleoside metabolic process GO:0046128 168 0.051
purine nucleoside catabolic process GO:0006152 124 0.050
multicellular organismal reproductive process GO:0048609 233 0.050
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.049
multicellular organism reproduction GO:0032504 233 0.049
response to nutrient levels GO:0031667 370 0.049
central nervous system development GO:0007417 311 0.048
cellular amine metabolic process GO:0044106 38 0.047
carbon catabolite activation of transcription GO:0045991 1 0.047
oxoacid metabolic process GO:0043436 290 0.046
organic cyclic compound catabolic process GO:1901361 175 0.046
purine containing compound catabolic process GO:0072523 138 0.046
immune system process GO:0002376 204 0.046
protein complex assembly GO:0006461 263 0.045
positive regulation of rna metabolic process GO:0051254 203 0.045
carbohydrate derivative catabolic process GO:1901136 147 0.045
rhythmic process GO:0048511 156 0.044
positive regulation of nucleic acid templated transcription GO:1903508 197 0.044
action potential GO:0001508 54 0.043
carboxylic acid metabolic process GO:0019752 289 0.043
macromolecular complex subunit organization GO:0043933 339 0.043
dna metabolic process GO:0006259 96 0.042
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.041
intracellular transport GO:0046907 185 0.041
cellular nitrogen compound catabolic process GO:0044270 163 0.041
regulation of programmed cell death GO:0043067 341 0.041
nitrogen compound transport GO:0071705 229 0.041
ribose phosphate metabolic process GO:0019693 235 0.040
chromosome segregation GO:0007059 2 0.039
neurological system process GO:0050877 219 0.039
positive regulation of molecular function GO:0044093 230 0.039
positive regulation of phosphorus metabolic process GO:0010562 262 0.039
organonitrogen compound catabolic process GO:1901565 179 0.039
nucleoside phosphate catabolic process GO:1901292 140 0.038
purine nucleoside metabolic process GO:0042278 169 0.038
glycosyl compound catabolic process GO:1901658 126 0.038
single organism biosynthetic process GO:0044711 342 0.038
purine nucleoside triphosphate catabolic process GO:0009146 122 0.038
anion transport GO:0006820 178 0.038
negative regulation of metabolic process GO:0009892 331 0.037
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.037
nuclear transport GO:0051169 49 0.037
negative regulation of response to stimulus GO:0048585 155 0.037
cellular component biogenesis GO:0044085 368 0.037
ribonucleoside catabolic process GO:0042454 126 0.037
cellular component assembly GO:0022607 360 0.037
amine metabolic process GO:0009308 38 0.036
negative regulation of cellular metabolic process GO:0031324 281 0.036
organic acid metabolic process GO:0006082 292 0.036
response to peptide GO:1901652 292 0.036
purine ribonucleotide metabolic process GO:0009150 227 0.035
purine nucleoside triphosphate metabolic process GO:0009144 141 0.035
positive regulation of neurogenesis GO:0050769 165 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
regulation of protein modification process GO:0031399 194 0.034
negative regulation of cell communication GO:0010648 158 0.034
regulation of cell differentiation GO:0045595 320 0.034
purine nucleotide metabolic process GO:0006163 229 0.034
negative regulation of rna metabolic process GO:0051253 123 0.034
regulation of neurogenesis GO:0050767 247 0.033
growth GO:0040007 165 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
positive regulation of nucleotide metabolic process GO:0045981 91 0.033
regulation of membrane potential GO:0042391 110 0.033
purine ribonucleoside catabolic process GO:0046130 124 0.033
regulation of molecular function GO:0065009 398 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
positive regulation of cell death GO:0010942 184 0.032
gliogenesis GO:0042063 93 0.032
protein oligomerization GO:0051259 191 0.031
positive regulation of nervous system development GO:0051962 178 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
cation transport GO:0006812 382 0.031
negative regulation of signaling GO:0023057 157 0.031
cardiovascular system development GO:0072358 134 0.031
gtp catabolic process GO:0006184 71 0.031
ribonucleoside triphosphate metabolic process GO:0009199 141 0.031
response to glucose GO:0009749 136 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
positive regulation of transcription factor import into nucleus GO:0042993 4 0.030
locomotion GO:0040011 237 0.030
protein transport GO:0015031 132 0.029
gland development GO:0048732 155 0.029
multicellular organismal signaling GO:0035637 44 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
single organism nuclear import GO:1902593 35 0.028
protein homooligomerization GO:0051260 91 0.027
nucleoside monophosphate metabolic process GO:0009123 93 0.027
apoptotic process GO:0006915 381 0.027
chemical homeostasis GO:0048878 292 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
cellular response to peptide hormone stimulus GO:0071375 120 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
cellular response to growth factor stimulus GO:0071363 162 0.027
negative regulation of biosynthetic process GO:0009890 168 0.027
transmission of nerve impulse GO:0019226 42 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
organelle organization GO:0006996 266 0.026
regulation of catabolic process GO:0009894 113 0.026
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.026
tissue development GO:0009888 252 0.026
secretion GO:0046903 307 0.025
gtp metabolic process GO:0046039 72 0.025
ribonucleoside triphosphate catabolic process GO:0009203 122 0.025
negative regulation of cell death GO:0060548 229 0.025
neuronal action potential GO:0019228 35 0.025
cellular response to endogenous stimulus GO:0071495 377 0.024
nucleoside triphosphate catabolic process GO:0009143 123 0.024
single organism catabolic process GO:0044712 283 0.024
sex differentiation GO:0007548 113 0.024
response to heat GO:0009408 60 0.024
protein localization to organelle GO:0033365 57 0.024
nucleoside catabolic process GO:0009164 126 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
regeneration GO:0031099 163 0.024
meiotic cell cycle process GO:1903046 3 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
ribonucleoside metabolic process GO:0009119 174 0.023
ion transmembrane transport GO:0034220 365 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
development of primary sexual characteristics GO:0045137 107 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
axon ensheathment GO:0008366 40 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
homeostatic process GO:0042592 331 0.023
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
negative regulation of signal transduction GO:0009968 83 0.023
cellular response to stress GO:0033554 269 0.023
positive regulation of cellular component organization GO:0051130 200 0.022
regulation of catalytic activity GO:0050790 304 0.022
response to inorganic substance GO:0010035 377 0.022
neuron development GO:0048666 286 0.022
cell cycle process GO:0022402 57 0.022
cell growth GO:0016049 104 0.022
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.022
protein phosphorylation GO:0006468 345 0.022
organophosphate biosynthetic process GO:0090407 143 0.022
protein localization to nucleus GO:0034504 39 0.022
response to mineralocorticoid GO:0051385 49 0.022
double strand break repair GO:0006302 1 0.022
response to corticosteroid GO:0031960 235 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
regulation of ion transport GO:0043269 245 0.022
regulation of cell cycle GO:0051726 73 0.021
eye morphogenesis GO:0048592 4 0.021
regulation of secretion by cell GO:1903530 208 0.021
response to hypoxia GO:0001666 231 0.021
negative regulation of molecular function GO:0044092 133 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.021
regulation of system process GO:0044057 208 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.021
ribonucleotide catabolic process GO:0009261 136 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
female pregnancy GO:0007565 122 0.020
response to growth factor GO:0070848 189 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.020
negative regulation of transcription dna templated GO:0045892 116 0.020
ncrna processing GO:0034470 3 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
response to decreased oxygen levels GO:0036293 237 0.020
carboxylic acid transport GO:0046942 115 0.020
neuron differentiation GO:0030182 368 0.020
single organism intracellular transport GO:1902582 166 0.020
regulation of intracellular transport GO:0032386 65 0.019
glial cell differentiation GO:0010001 65 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
proteolysis GO:0006508 175 0.019
positive regulation of cellular catabolic process GO:0031331 71 0.019
regulation of nucleotide catabolic process GO:0030811 65 0.019
cell projection organization GO:0030030 302 0.019
response to oxygen levels GO:0070482 265 0.019
protein import into nucleus GO:0006606 35 0.019
female gonad development GO:0008585 53 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
ensheathment of neurons GO:0007272 40 0.018
defense response GO:0006952 194 0.018
sexual reproduction GO:0019953 148 0.018
cell cycle GO:0007049 101 0.018
response to hexose GO:0009746 144 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
behavior GO:0007610 205 0.018
cellular component movement GO:0006928 248 0.018
regulation of dna metabolic process GO:0051052 60 0.018
gamete generation GO:0007276 124 0.018
positive regulation of signal transduction GO:0009967 175 0.018
regulation of cellular catabolic process GO:0031329 101 0.018
regulation of nervous system development GO:0051960 264 0.018
aging GO:0007568 241 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
cellular response to peptide GO:1901653 133 0.018
positive regulation of protein modification process GO:0031401 142 0.018
positive regulation of signaling GO:0023056 270 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
response to carbohydrate GO:0009743 183 0.017
regulation of cellular component organization GO:0051128 368 0.017
transmembrane transport GO:0055085 412 0.017
response to radiation GO:0009314 137 0.017
response to glucocorticoid GO:0051384 223 0.017
positive regulation of cell development GO:0010720 176 0.017
cell activation GO:0001775 97 0.017
coenzyme metabolic process GO:0006732 86 0.017
divalent metal ion transport GO:0070838 132 0.017
regulation of neuron death GO:1901214 115 0.016
developmental growth GO:0048589 100 0.016
regulation of nucleoside metabolic process GO:0009118 66 0.016
necroptotic process GO:0070266 2 0.016
carbohydrate metabolic process GO:0005975 130 0.016
secretion by cell GO:0032940 248 0.016
motor neuron axon guidance GO:0008045 1 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
nucleocytoplasmic transport GO:0006913 48 0.016
protein modification by small protein conjugation or removal GO:0070647 35 0.016
eye development GO:0001654 50 0.016
response to estrogen GO:0043627 232 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
negative regulation of programmed cell death GO:0043069 183 0.015
negative regulation of cell cycle phase transition GO:1901988 4 0.015
guanosine containing compound metabolic process GO:1901068 74 0.015
heart development GO:0007507 72 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
peptidyl amino acid modification GO:0018193 126 0.015
heart morphogenesis GO:0003007 3 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
spindle organization GO:0007051 2 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
adult locomotory behavior GO:0008344 4 0.015
protein heterooligomerization GO:0051291 89 0.015
regulation of hydrolase activity GO:0051336 143 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
dendrite development GO:0016358 72 0.014
regulation of neuron differentiation GO:0045664 208 0.014
embryo development GO:0009790 49 0.014
establishment of protein localization to organelle GO:0072594 44 0.014
lipid biosynthetic process GO:0008610 128 0.014
small molecule biosynthetic process GO:0044283 124 0.014
neuron projection development GO:0031175 273 0.014
purine nucleoside monophosphate metabolic process GO:0009126 84 0.014
positive regulation of catabolic process GO:0009896 78 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
negative regulation of rna splicing GO:0033119 3 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
cytoplasmic transport GO:0016482 115 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
lipid storage GO:0019915 1 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
amino acid transport GO:0006865 70 0.014
regulation of signal transduction GO:0009966 318 0.013
gastrulation GO:0007369 2 0.013
regulation of gtpase activity GO:0043087 57 0.013
protein targeting to nucleus GO:0044744 35 0.013
positive regulation of cell communication GO:0010647 271 0.013
dna modification GO:0006304 12 0.013
negative regulation of neuron death GO:1901215 69 0.013
mrna metabolic process GO:0016071 20 0.013
detection of visible light GO:0009584 3 0.013
development of primary female sexual characteristics GO:0046545 56 0.013
protein import GO:0017038 37 0.013
protein localization to membrane GO:0072657 36 0.013
viral transcription GO:0019083 2 0.013
cell projection morphogenesis GO:0048858 123 0.013
cardiac chamber development GO:0003205 1 0.013
localization of cell GO:0051674 202 0.013
calcium ion homeostasis GO:0055074 162 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
cellular chemical homeostasis GO:0055082 247 0.013
circulatory system development GO:0072359 134 0.013
cell type specific apoptotic process GO:0097285 134 0.013
single organism membrane organization GO:0044802 74 0.013
regulation of protein localization GO:0032880 81 0.013
response to purine containing compound GO:0014074 126 0.012
regulation of protein import into nucleus GO:0042306 24 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
cellular ketone metabolic process GO:0042180 51 0.012
positive regulation of gtpase activity GO:0043547 47 0.012
neuron death GO:0070997 127 0.012
regulation of cell projection organization GO:0031344 175 0.012
sensory organ development GO:0007423 74 0.012
regulation of secretion GO:0051046 224 0.012
monosaccharide metabolic process GO:0005996 61 0.012
response to temperature stimulus GO:0009266 94 0.012
negative regulation of developmental process GO:0051093 125 0.012
organelle fission GO:0048285 25 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
response to vitamin GO:0033273 131 0.012
histone h3 acetylation GO:0043966 2 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
organic acid transport GO:0015849 116 0.012
male gamete generation GO:0048232 99 0.012
serine family amino acid metabolic process GO:0009069 12 0.012
ovulation cycle GO:0042698 67 0.012
membrane organization GO:0061024 94 0.012
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.012
metal ion homeostasis GO:0055065 186 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
cell migration GO:0016477 197 0.012
hexose metabolic process GO:0019318 58 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
hormone transport GO:0009914 121 0.011
dendrite morphogenesis GO:0048813 43 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
organic anion transport GO:0015711 132 0.011
metal ion transport GO:0030001 289 0.011
regulation of neuron projection development GO:0010975 161 0.011
female sex differentiation GO:0046660 59 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
organic acid biosynthetic process GO:0016053 83 0.011
axis specification GO:0009798 4 0.011
response to estradiol GO:0032355 164 0.011
insulin receptor signaling pathway GO:0008286 24 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
cellular homeostasis GO:0019725 252 0.011
circulatory system process GO:0003013 183 0.011
central nervous system neuron axonogenesis GO:0021955 1 0.011
cation homeostasis GO:0055080 195 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
nucleoside monophosphate catabolic process GO:0009125 56 0.011
cellular protein complex assembly GO:0043623 44 0.011
response to cytokine GO:0034097 215 0.011
response to biotic stimulus GO:0009607 226 0.011
regulation of growth GO:0040008 105 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
regulation of nucleocytoplasmic transport GO:0046822 28 0.011
cellular amino acid biosynthetic process GO:0008652 32 0.010
cell motility GO:0048870 202 0.010
regulation of cell growth GO:0001558 85 0.010
myelination GO:0042552 39 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
leukocyte activation GO:0045321 76 0.010
negative regulation of transport GO:0051051 136 0.010
positive regulation of transport GO:0051050 245 0.010
receptor mediated endocytosis GO:0006898 42 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
multicellular organism growth GO:0035264 1 0.010
leukocyte differentiation GO:0002521 30 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
response to activity GO:0014823 73 0.010
positive regulation of gtp catabolic process GO:0033126 48 0.010
response to light stimulus GO:0009416 52 0.010
response to corticosterone GO:0051412 40 0.010
multi multicellular organism process GO:0044706 138 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
cellular cation homeostasis GO:0030003 180 0.010
cellular response to nutrient GO:0031670 30 0.010
camera type eye morphogenesis GO:0048593 2 0.010

Thop1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.015
disease of anatomical entity DOID:7 0 0.015
cardiovascular system disease DOID:1287 0 0.015
nervous system disease DOID:863 0 0.013
organ system cancer DOID:0050686 0 0.012