Rattus norvegicus

106 known processes

Thra

thyroid hormone receptor alpha

(Aliases: Thra1,ERBA1)

Thra biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of synapse maturation GO:0090128 2 0.392
regulation of transcription dna templated GO:0006355 374 0.343
regulation of rna metabolic process GO:0051252 391 0.307
regulation of multicellular organismal development GO:2000026 376 0.265
Rat
positive regulation of synapse maturation GO:0090129 2 0.265
regulation of cellular component organization GO:0051128 368 0.252
Human
macromolecule localization GO:0033036 252 0.221
Mouse
regulation of cell differentiation GO:0045595 320 0.196
Mouse Rat
negative regulation of cellular metabolic process GO:0031324 281 0.189
Human Zebrafish Mouse Rat
negative regulation of metabolic process GO:0009892 331 0.189
Human Zebrafish Mouse Rat
regulation of phosphate metabolic process GO:0019220 349 0.183
Rat
response to metal ion GO:0010038 253 0.181
transcription dna templated GO:0006351 377 0.177
response to inorganic substance GO:0010035 377 0.176
regulation of nucleic acid templated transcription GO:1903506 380 0.175
cellular response to oxygen containing compound GO:1901701 386 0.172
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.170
regulation of cell development GO:0060284 263 0.166
Rat
cellular component biogenesis GO:0044085 368 0.166
Human
nucleic acid templated transcription GO:0097659 379 0.157
rna metabolic process GO:0016070 406 0.153
positive regulation of signaling GO:0023056 270 0.143
Rat
organelle organization GO:0006996 266 0.142
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.138
intracellular signal transduction GO:0035556 314 0.133
Rat
regulation of protein metabolic process GO:0051246 289 0.124
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.122
Rat
protein localization GO:0008104 191 0.121
Mouse
cell projection organization GO:0030030 302 0.118
rna biosynthetic process GO:0032774 380 0.115
lipid metabolic process GO:0006629 283 0.115
Mouse Rat
locomotion GO:0040011 237 0.114
negative regulation of macromolecule metabolic process GO:0010605 260 0.107
Human Zebrafish Mouse Rat
regulation of apoptotic process GO:0042981 335 0.106
Mouse Rat
apoptotic process GO:0006915 381 0.106
Mouse Rat
regulation of molecular function GO:0065009 398 0.105
negative regulation of biosynthetic process GO:0009890 168 0.103
Human Zebrafish Mouse Rat
negative regulation of protein metabolic process GO:0051248 114 0.099
Rat
cellular response to lipid GO:0071396 201 0.097
Rat
central nervous system development GO:0007417 311 0.096
transcription from rna polymerase ii promoter GO:0006366 252 0.096
response to acid chemical GO:0001101 222 0.096
Rat
cellular response to endogenous stimulus GO:0071495 377 0.094
Human Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.093
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.092
Human Zebrafish Mouse
cyclic nucleotide metabolic process GO:0009187 80 0.091
neuron apoptotic process GO:0051402 88 0.090
negative regulation of cellular biosynthetic process GO:0031327 161 0.089
Human Zebrafish Mouse Rat
cell migration GO:0016477 197 0.089
positive regulation of transcription dna templated GO:0045893 197 0.089
programmed cell death GO:0012501 392 0.088
Mouse Rat
cellular response to organonitrogen compound GO:0071417 197 0.087
regulation of rna biosynthetic process GO:2001141 381 0.087
g protein coupled receptor signaling pathway GO:0007186 242 0.085
taxis GO:0042330 67 0.085
regulation of neuron differentiation GO:0045664 208 0.085
Rat
regulation of catalytic activity GO:0050790 304 0.084
Rat
enzyme linked receptor protein signaling pathway GO:0007167 116 0.082
response to extracellular stimulus GO:0009991 380 0.082
organophosphate metabolic process GO:0019637 370 0.082
Rat
cellular macromolecule localization GO:0070727 122 0.081
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.076
positive regulation of rna metabolic process GO:0051254 203 0.076
nucleoside phosphate metabolic process GO:0006753 283 0.075
positive regulation of programmed cell death GO:0043068 157 0.075
positive regulation of cell communication GO:0010647 271 0.075
Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.074
Human Zebrafish Mouse
cellular amino acid metabolic process GO:0006520 107 0.074
negative regulation of molecular function GO:0044092 133 0.072
positive regulation of cellular component organization GO:0051130 200 0.072
positive regulation of gene expression GO:0010628 244 0.072
single organism cellular localization GO:1902580 102 0.071
Mouse
response to nutrient levels GO:0031667 370 0.071
anatomical structure morphogenesis GO:0009653 298 0.070
Mouse
regulation of nervous system development GO:0051960 264 0.068
Rat
neuron differentiation GO:0030182 368 0.067
Rat
positive regulation of cell death GO:0010942 184 0.067
nucleotide metabolic process GO:0009117 279 0.067
regulation of cellular protein metabolic process GO:0032268 267 0.066
Rat
growth GO:0040007 165 0.065
carboxylic acid metabolic process GO:0019752 289 0.064
regulation of cell proliferation GO:0042127 359 0.064
Rat
response to peptide GO:1901652 292 0.063
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.062
Human Zebrafish Mouse Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.062
negative regulation of cyclic nucleotide metabolic process GO:0030800 15 0.062
negative regulation of camp metabolic process GO:0030815 14 0.061
cellular lipid metabolic process GO:0044255 208 0.060
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.060
regulation of neuron death GO:1901214 115 0.060
regulation of signal transduction GO:0009966 318 0.059
Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.059
regulation of cellular localization GO:0060341 263 0.058
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.058
carbohydrate derivative metabolic process GO:1901135 346 0.058
reproductive process GO:0022414 372 0.057
Mouse Rat
positive regulation of synaptic transmission GO:0050806 62 0.057
negative regulation of gene expression GO:0010629 199 0.057
Human Zebrafish Mouse Rat
cell motility GO:0048870 202 0.057
positive regulation of rna biosynthetic process GO:1902680 197 0.055
organic acid metabolic process GO:0006082 292 0.055
negative regulation of multicellular organismal process GO:0051241 203 0.054
positive regulation of phosphorus metabolic process GO:0010562 262 0.053
Rat
negative regulation of phosphate metabolic process GO:0045936 80 0.053
positive regulation of intracellular signal transduction GO:1902533 138 0.053
Rat
positive regulation of transport GO:0051050 245 0.053
positive regulation of nucleic acid templated transcription GO:1903508 197 0.053
cellular component movement GO:0006928 248 0.052
positive regulation of biosynthetic process GO:0009891 319 0.052
neuron death GO:0070997 127 0.052
regulation of phosphorylation GO:0042325 248 0.051
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.051
Human Zebrafish Mouse Rat
purine containing compound metabolic process GO:0072521 253 0.050
regulation of programmed cell death GO:0043067 341 0.050
Mouse Rat
secretion by cell GO:0032940 248 0.048
organonitrogen compound biosynthetic process GO:1901566 167 0.048
vesicle mediated transport GO:0016192 181 0.048
negative regulation of adenylate cyclase activity GO:0007194 7 0.048
neuron projection morphogenesis GO:0048812 122 0.047
blood circulation GO:0008015 183 0.047
Mouse
cognition GO:0050890 92 0.046
Mouse
protein phosphorylation GO:0006468 345 0.045
cellular response to peptide GO:1901653 133 0.045
single organism reproductive process GO:0044702 297 0.044
Rat
tissue development GO:0009888 252 0.044
Mouse Rat
oxoacid metabolic process GO:0043436 290 0.044
macromolecular complex subunit organization GO:0043933 339 0.044
Human
regulation of cellular component biogenesis GO:0044087 86 0.044
Human
endocytosis GO:0006897 84 0.044
signal transduction by phosphorylation GO:0023014 144 0.044
Rat
negative regulation of protein import into nucleus translocation GO:0033159 1 0.043
response to ethanol GO:0045471 162 0.042
Rat
negative regulation of cell communication GO:0010648 158 0.042
response to camp GO:0051591 91 0.042
positive regulation of cellular protein metabolic process GO:0032270 167 0.042
regulation of secretion by cell GO:1903530 208 0.042
regulation of synaptic transmission GO:0050804 141 0.041
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.041
single organism organelle organization GO:1902589 180 0.040
response to biotic stimulus GO:0009607 226 0.040
chemotaxis GO:0006935 66 0.040
regulation of nucleotide metabolic process GO:0006140 117 0.040
mapk cascade GO:0000165 140 0.040
Rat
response to purine containing compound GO:0014074 126 0.040
cellular component assembly GO:0022607 360 0.039
Human
cellular response to organic cyclic compound GO:0071407 202 0.039
purine ribonucleotide metabolic process GO:0009150 227 0.039
positive regulation of phosphorylation GO:0042327 177 0.038
Rat
regulation of neurogenesis GO:0050767 247 0.038
Rat
organophosphate biosynthetic process GO:0090407 143 0.038
cellular calcium ion homeostasis GO:0006874 160 0.037
catabolic process GO:0009056 351 0.037
Mouse
regulation of purine nucleotide metabolic process GO:1900542 115 0.037
positive regulation of response to stimulus GO:0048584 285 0.037
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.037
regulation of cell migration GO:0030334 128 0.037
metal ion homeostasis GO:0055065 186 0.037
positive regulation of cell proliferation GO:0008284 249 0.036
Rat
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.036
cellular response to stress GO:0033554 269 0.036
regulation of cell projection organization GO:0031344 175 0.036
glycerolipid metabolic process GO:0046486 67 0.036
Rat
regulation of cellular component movement GO:0051270 150 0.035
regulation of organelle organization GO:0033043 80 0.035
positive regulation of locomotion GO:0040017 102 0.035
protein targeting GO:0006605 61 0.035
Mouse
response to reactive oxygen species GO:0000302 120 0.035
cellular response to metal ion GO:0071248 55 0.035
cell type specific apoptotic process GO:0097285 134 0.035
Mouse
localization of cell GO:0051674 202 0.035
negative regulation of rna metabolic process GO:0051253 123 0.034
Human Zebrafish Mouse
positive regulation of molecular function GO:0044093 230 0.033
amine metabolic process GO:0009308 38 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
purine nucleotide metabolic process GO:0006163 229 0.033
cell projection assembly GO:0030031 21 0.033
positive regulation of apoptotic process GO:0043065 154 0.033
cellular ketone metabolic process GO:0042180 51 0.032
response to nutrient GO:0007584 248 0.032
Rat
regulation of adenylate cyclase activity GO:0045761 18 0.032
nucleoside phosphate biosynthetic process GO:1901293 102 0.032
regulation of camp metabolic process GO:0030814 43 0.032
cellular homeostasis GO:0019725 252 0.031
negative regulation of transcription dna templated GO:0045892 116 0.031
Human Zebrafish Mouse
peptidyl amino acid modification GO:0018193 126 0.031
neurological system process GO:0050877 219 0.031
Mouse
establishment of protein localization GO:0045184 141 0.031
Mouse
intracellular protein transport GO:0006886 79 0.031
Mouse
protein transport GO:0015031 132 0.031
Mouse
cell growth GO:0016049 104 0.031
ribonucleotide metabolic process GO:0009259 231 0.031
cellular response to nitrogen compound GO:1901699 210 0.030
aging GO:0007568 241 0.030
purine ribonucleoside catabolic process GO:0046130 124 0.030
single organism catabolic process GO:0044712 283 0.030
Mouse
regulation of protein modification process GO:0031399 194 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
Human Zebrafish Mouse
regulation of secretion GO:0051046 224 0.030
positive regulation of secretion by cell GO:1903532 128 0.030
positive regulation of protein modification process GO:0031401 142 0.030
hormone secretion GO:0046879 115 0.030
cellular component morphogenesis GO:0032989 155 0.030
camp biosynthetic process GO:0006171 47 0.029
neuron projection development GO:0031175 273 0.029
divalent metal ion transport GO:0070838 132 0.029
response to fatty acid GO:0070542 65 0.029
multicellular organism reproduction GO:0032504 233 0.029
Mouse
protein complex subunit organization GO:0071822 302 0.029
Human
cell cycle GO:0007049 101 0.029
regulation of intracellular signal transduction GO:1902531 218 0.029
Rat
membrane repolarization GO:0086009 1 0.029
response to peptide hormone GO:0043434 278 0.029
positive regulation of signal transduction GO:0009967 175 0.029
Rat
single organism biosynthetic process GO:0044711 342 0.028
intracellular transport GO:0046907 185 0.028
Mouse
response to external biotic stimulus GO:0043207 221 0.028
axon development GO:0061564 96 0.028
regulation of locomotion GO:0040012 148 0.028
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.028
response to oxidative stress GO:0006979 186 0.028
cell cell signaling GO:0007267 335 0.028
Rat
ribose phosphate biosynthetic process GO:0046390 87 0.028
reproduction GO:0000003 245 0.028
Mouse
cell part morphogenesis GO:0032990 123 0.028
inorganic ion transmembrane transport GO:0098660 229 0.028
anterior posterior pattern specification GO:0009952 1 0.027
regulation of neuron apoptotic process GO:0043523 83 0.027
action potential GO:0001508 54 0.027
sexual reproduction GO:0019953 148 0.027
Mouse
cellular catabolic process GO:0044248 295 0.027
cell morphogenesis GO:0000902 142 0.027
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.027
positive regulation of cellular component movement GO:0051272 102 0.026
response to transition metal nanoparticle GO:1990267 122 0.026
negative regulation of cellular protein metabolic process GO:0032269 106 0.026
Rat
regulation of neuron projection development GO:0010975 161 0.026
regulation of cell motility GO:2000145 131 0.026
synaptic transmission GO:0007268 235 0.026
Rat
defense response GO:0006952 194 0.026
learning or memory GO:0007611 90 0.026
Mouse
phospholipid metabolic process GO:0006644 61 0.026
Rat
circulatory system development GO:0072359 134 0.025
immune system process GO:0002376 204 0.025
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 117 0.025
Human Zebrafish Mouse
ion homeostasis GO:0050801 212 0.025
regulation of kinase activity GO:0043549 117 0.025
Rat
behavior GO:0007610 205 0.025
Mouse
signal release GO:0023061 145 0.025
chemical homeostasis GO:0048878 292 0.025
regulation of hydrolase activity GO:0051336 143 0.025
response to growth factor GO:0070848 189 0.025
regulation of camp biosynthetic process GO:0030817 38 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.025
regulation of protein transport GO:0051223 68 0.024
Mouse
positive regulation of catalytic activity GO:0043085 184 0.024
negative regulation of developmental process GO:0051093 125 0.024
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
cytoskeleton organization GO:0007010 111 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
negative regulation of response to stimulus GO:0048585 155 0.023
positive regulation of developmental process GO:0051094 283 0.023
Mouse Rat
cation transport GO:0006812 382 0.023
axis specification GO:0009798 4 0.023
negative regulation of phosphorus metabolic process GO:0010563 80 0.023
nucleoside metabolic process GO:0009116 179 0.023
single organism intracellular transport GO:1902582 166 0.023
Mouse
activation of jak2 kinase activity GO:0042977 2 0.023
cellular chemical homeostasis GO:0055082 247 0.023
cyclic nucleotide biosynthetic process GO:0009190 63 0.023
second messenger mediated signaling GO:0019932 51 0.023
response to amino acid GO:0043200 75 0.023
positive regulation of mapk cascade GO:0043410 92 0.022
Rat
purine ribonucleotide biosynthetic process GO:0009152 81 0.022
negative regulation of signaling GO:0023057 157 0.022
cellular amine metabolic process GO:0044106 38 0.022
negative regulation of catalytic activity GO:0043086 103 0.022
purine nucleotide biosynthetic process GO:0006164 83 0.022
negative regulation of cell proliferation GO:0008285 119 0.022
Rat
protein targeting to nucleus GO:0044744 35 0.022
Mouse
glutamate receptor signaling pathway GO:0007215 43 0.022
regulation of growth GO:0040008 105 0.022
negative regulation of signal transduction GO:0009968 83 0.022
ossification GO:0001503 70 0.022
Mouse Rat
cellular response to insulin stimulus GO:0032869 81 0.022
response to insulin GO:0032868 133 0.022
cellular response to external stimulus GO:0071496 118 0.022
positive regulation of cell motility GO:2000147 97 0.022
maintenance of location GO:0051235 17 0.022
Mouse
embryonic pattern specification GO:0009880 1 0.022
protein maturation GO:0051604 68 0.022
positive regulation of protein metabolic process GO:0051247 178 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
cellular protein localization GO:0034613 122 0.021
Mouse
microvillus assembly GO:0030033 2 0.021
regulation of establishment of protein localization GO:0070201 69 0.021
Mouse
multi organism reproductive process GO:0044703 262 0.021
Mouse Rat
neuron development GO:0048666 286 0.021
guanosine containing compound metabolic process GO:1901068 74 0.021
response to molecule of bacterial origin GO:0002237 194 0.021
cellular cation homeostasis GO:0030003 180 0.021
ribose phosphate metabolic process GO:0019693 235 0.020
negative regulation of transport GO:0051051 136 0.020
Mouse
head development GO:0060322 247 0.020
regulation of lyase activity GO:0051339 22 0.020
neuron projection guidance GO:0097485 24 0.020
regulation of ion transport GO:0043269 245 0.020
purine containing compound biosynthetic process GO:0072522 85 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
Rat
nucleotide biosynthetic process GO:0009165 98 0.020
calcium ion transmembrane transport GO:0070588 70 0.020
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.020
positive regulation of transferase activity GO:0051347 81 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
establishment of protein localization to organelle GO:0072594 44 0.019
Mouse
single organism nuclear import GO:1902593 35 0.019
Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
chemosensory behavior GO:0007635 2 0.019
regulation of protein localization GO:0032880 81 0.019
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
gastrulation GO:0007369 2 0.019
response to corticosteroid GO:0031960 235 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
macromolecular complex assembly GO:0065003 273 0.019
Human
limbic system development GO:0021761 38 0.019
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.019
sequestering of metal ion GO:0051238 9 0.019
response to glucose GO:0009749 136 0.019
protein localization to nucleus GO:0034504 39 0.018
Mouse
negative regulation of neurogenesis GO:0050768 78 0.018
forebrain development GO:0030900 98 0.018
Rat
arachidonic acid metabolic process GO:0019369 20 0.018
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 12 0.018
regulation of vesicle mediated transport GO:0060627 81 0.018
response to hypoxia GO:0001666 231 0.018
gamete generation GO:0007276 124 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.018
Human Zebrafish
sequestering of calcium ion GO:0051208 8 0.018
monocarboxylic acid metabolic process GO:0032787 152 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
metal ion transport GO:0030001 289 0.018
lipid localization GO:0010876 62 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
regulation of protein targeting GO:1903533 28 0.018
Mouse
ribonucleotide catabolic process GO:0009261 136 0.018
regulation of intracellular transport GO:0032386 65 0.018
Mouse
establishment of tissue polarity GO:0007164 2 0.018
regulation of nucleotide biosynthetic process GO:0030808 47 0.018
calcium ion transport GO:0006816 131 0.018
calcium ion homeostasis GO:0055074 162 0.018
nucleotide catabolic process GO:0009166 139 0.017
regulation of activation of jak2 kinase activity GO:0010534 1 0.017
cell adhesion GO:0007155 110 0.017
positive regulation of neuron apoptotic process GO:0043525 33 0.017
response to monosaccharide GO:0034284 159 0.017
regulation of cell growth GO:0001558 85 0.017
positive regulation of nervous system development GO:0051962 178 0.017
Rat
insulin secretion GO:0030073 69 0.017
cyclic purine nucleotide metabolic process GO:0052652 62 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
negative regulation of cell development GO:0010721 82 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
Mouse
positive regulation of secretion GO:0051047 140 0.017
protein complex biogenesis GO:0070271 263 0.017
Human
regulation of response to external stimulus GO:0032101 106 0.016
lipid storage GO:0019915 1 0.016
regulation of hormone levels GO:0010817 187 0.016
response to vitamin GO:0033273 131 0.016
Rat
embryonic limb morphogenesis GO:0030326 4 0.016
positive regulation of cell migration GO:0030335 96 0.016
regulation of membrane potential GO:0042391 110 0.016
divalent inorganic cation transport GO:0072511 134 0.016
circulatory system process GO:0003013 183 0.016
Mouse
positive regulation of kinase activity GO:0033674 77 0.016
negative regulation of nucleotide metabolic process GO:0045980 23 0.016
response to carbohydrate GO:0009743 183 0.016
fatty acid metabolic process GO:0006631 99 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
response to glucocorticoid GO:0051384 223 0.016
regulation of metal ion transport GO:0010959 118 0.016
regulation of protein processing GO:0070613 50 0.016
neuromuscular process GO:0050905 2 0.016
cellular response to nutrient levels GO:0031669 60 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
positive regulation of protein transport GO:0051222 41 0.016
positive regulation of hydrolase activity GO:0051345 86 0.015
negative regulation of cyclase activity GO:0031280 7 0.015
ras protein signal transduction GO:0007265 29 0.015
protein localization to organelle GO:0033365 57 0.015
Mouse
long chain fatty acid metabolic process GO:0001676 32 0.015
cellular response to extracellular stimulus GO:0031668 73 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
regulation of carbohydrate metabolic process GO:0006109 41 0.015
response to calcium ion GO:0051592 59 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
protein processing GO:0016485 68 0.015
regulation of meiotic cell cycle GO:0051445 3 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
single organism behavior GO:0044708 130 0.015
Mouse
cardiac chamber development GO:0003205 1 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
negative regulation of purine nucleotide metabolic process GO:1900543 23 0.015
organic substance catabolic process GO:1901575 316 0.015
Mouse
cellular response to acid chemical GO:0071229 75 0.015
Rat
synaptic vesicle endocytosis GO:0048488 4 0.015
regulation of cyclase activity GO:0031279 21 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
amide transport GO:0042886 105 0.015
developmental maturation GO:0021700 25 0.015
smooth muscle cell proliferation GO:0048659 77 0.014
positive regulation of protein kinase activity GO:0045860 73 0.014
synapse organization GO:0050808 46 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
cytoplasmic transport GO:0016482 115 0.014
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
negative regulation of cell death GO:0060548 229 0.014
regulation of transferase activity GO:0051338 123 0.014
Rat
cellular response to inorganic substance GO:0071241 65 0.014
regulation of transmembrane transport GO:0034762 122 0.014
regulation of mapk cascade GO:0043408 116 0.014
Rat
organophosphate catabolic process GO:0046434 148 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
protein complex assembly GO:0006461 263 0.014
Human
peptide transport GO:0015833 97 0.014
regulation of dendrite development GO:0050773 59 0.014
nuclear import GO:0051170 35 0.014
Mouse
negative regulation of protein processing GO:0010955 47 0.014
peptide hormone secretion GO:0030072 84 0.014
proteolysis GO:0006508 175 0.014
activation of protein kinase activity GO:0032147 47 0.014
motor neuron axon guidance GO:0008045 1 0.014
regulation of catabolic process GO:0009894 113 0.014
Mouse
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
regulation of peptide transport GO:0090087 87 0.014
response to ketone GO:1901654 182 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
aromatic compound catabolic process GO:0019439 168 0.014
male mating behavior GO:0060179 3 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
immune response GO:0006955 104 0.013
glucose homeostasis GO:0042593 75 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
Rat
positive regulation of cell differentiation GO:0045597 217 0.013
Mouse Rat
associative learning GO:0008306 19 0.013
gtp metabolic process GO:0046039 72 0.013
response to hexose GO:0009746 144 0.013
jak stat cascade GO:0007259 26 0.013
axonogenesis GO:0007409 71 0.013
cation transmembrane transport GO:0098655 263 0.013
brain development GO:0007420 247 0.013
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.013
protein secretion GO:0009306 34 0.013
regulation of defense response GO:0031347 68 0.013
nucleoside catabolic process GO:0009164 126 0.013
response to wounding GO:0009611 254 0.013
learning GO:0007612 33 0.013
homeostatic process GO:0042592 331 0.013
Mouse
mesoderm development GO:0007498 2 0.013
regulation of synaptic plasticity GO:0048167 70 0.013
Rat
actin filament based process GO:0030029 86 0.012
regulation of gluconeogenesis GO:0006111 4 0.012
sulfur compound metabolic process GO:0006790 70 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
Human Mouse
regulation of system process GO:0044057 208 0.012
Mouse
olfactory learning GO:0008355 1 0.012
protein oligomerization GO:0051259 191 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
calcium mediated signaling using intracellular calcium source GO:0035584 1 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
peptide biosynthetic process GO:0043043 3 0.012
regulation of cellular response to stress GO:0080135 49 0.012
tube development GO:0035295 89 0.012
response to lipopolysaccharide GO:0032496 191 0.012
hormone transport GO:0009914 121 0.012
secretion GO:0046903 307 0.012
camp metabolic process GO:0046058 63 0.012
response to decreased oxygen levels GO:0036293 237 0.012
stress activated protein kinase signaling cascade GO:0031098 37 0.012
actin cytoskeleton organization GO:0030036 73 0.012
negative regulation of secretion GO:0051048 82 0.012
sex differentiation GO:0007548 113 0.012
Rat
positive regulation of cell development GO:0010720 176 0.012
Rat
regulation of protein kinase activity GO:0045859 105 0.012
positive regulation of receptor activity GO:2000273 4 0.012
protein import into nucleus GO:0006606 35 0.012
Mouse
heart contraction GO:0060047 57 0.012
Mouse
regulation of blood circulation GO:1903522 110 0.012
Mouse
negative regulation of phosphorylation GO:0042326 57 0.011

Thra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
Human
nervous system disease DOID:863 0 0.022
central nervous system disease DOID:331 0 0.013