Rattus norvegicus

18 known processes

Thrsp

thyroid hormone responsive

(Aliases: SPOT14,Lpgp,S14)

Thrsp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to metal ion GO:0010038 253 0.180
regulation of hormone levels GO:0010817 187 0.163
response to nutrient levels GO:0031667 370 0.144
response to extracellular stimulus GO:0009991 380 0.141
lipid biosynthetic process GO:0008610 128 0.139
secretion by cell GO:0032940 248 0.127
regulation of lipid metabolic process GO:0019216 68 0.127
homeostatic process GO:0042592 331 0.118
response to purine containing compound GO:0014074 126 0.112
negative regulation of serine type endopeptidase activity GO:1900004 1 0.098
response to transition metal nanoparticle GO:1990267 122 0.097
programmed cell death GO:0012501 392 0.095
response to peptide hormone GO:0043434 278 0.094
carboxylic acid metabolic process GO:0019752 289 0.091
organic acid metabolic process GO:0006082 292 0.090
single organism biosynthetic process GO:0044711 342 0.082
regulation of secretion by cell GO:1903530 208 0.080
response to carbohydrate GO:0009743 183 0.079
negative regulation of cellular metabolic process GO:0031324 281 0.078
catabolic process GO:0009056 351 0.075
hormone metabolic process GO:0042445 69 0.075
carbohydrate metabolic process GO:0005975 130 0.075
regulation of cellular catabolic process GO:0031329 101 0.069
lipid metabolic process GO:0006629 283 0.067
multi organism reproductive process GO:0044703 262 0.066
response to inorganic substance GO:0010035 377 0.066
chemical homeostasis GO:0048878 292 0.066
secretion GO:0046903 307 0.065
cellular lipid metabolic process GO:0044255 208 0.064
cellular response to insulin stimulus GO:0032869 81 0.063
response to hypoxia GO:0001666 231 0.063
cellular catabolic process GO:0044248 295 0.062
multicellular organism reproduction GO:0032504 233 0.061
small molecule biosynthetic process GO:0044283 124 0.060
cellular response to fluid shear stress GO:0071498 4 0.058
reproductive process GO:0022414 372 0.058
regulation of nucleic acid templated transcription GO:1903506 380 0.057
response to decreased oxygen levels GO:0036293 237 0.057
cellular response to hormone stimulus GO:0032870 247 0.056
regulation of apoptotic process GO:0042981 335 0.056
response to nutrient GO:0007584 248 0.055
cellular response to nitrogen compound GO:1901699 210 0.054
urogenital system development GO:0001655 78 0.054
tissue remodeling GO:0048771 40 0.052
signal release GO:0023061 145 0.052
regulation of molecular function GO:0065009 398 0.052
developmental process involved in reproduction GO:0003006 159 0.051
regulation of catabolic process GO:0009894 113 0.050
organophosphate metabolic process GO:0019637 370 0.050
organic anion transport GO:0015711 132 0.049
cellular response to external stimulus GO:0071496 118 0.049
reproduction GO:0000003 245 0.048
organ regeneration GO:0031100 101 0.048
cellular response to peptide hormone stimulus GO:0071375 120 0.048
cellular response to stress GO:0033554 269 0.047
cellular response to peptide GO:1901653 133 0.047
multicellular organism growth GO:0035264 1 0.047
oxidation reduction process GO:0055114 304 0.047
regulation of cellular amine metabolic process GO:0033238 8 0.047
response to oxygen levels GO:0070482 265 0.046
negative regulation of metabolic process GO:0009892 331 0.046
synaptic transmission GO:0007268 235 0.046
response to camp GO:0051591 91 0.046
cellular ketone metabolic process GO:0042180 51 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.045
inflammatory response GO:0006954 150 0.045
response to zinc ion GO:0010043 39 0.044
cellular response to organonitrogen compound GO:0071417 197 0.044
regulation of programmed cell death GO:0043067 341 0.042
cellular response to oxygen containing compound GO:1901701 386 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
glucose homeostasis GO:0042593 75 0.041
tonic smooth muscle contraction GO:0014820 4 0.041
defense response GO:0006952 194 0.041
regulation of phosphorus metabolic process GO:0051174 349 0.040
cellular response to endogenous stimulus GO:0071495 377 0.040
regeneration GO:0031099 163 0.040
aging GO:0007568 241 0.040
transcription dna templated GO:0006351 377 0.040
multi multicellular organism process GO:0044706 138 0.039
response to biotic stimulus GO:0009607 226 0.039
multicellular organismal reproductive process GO:0048609 233 0.039
nitrogen compound transport GO:0071705 229 0.039
response to insulin GO:0032868 133 0.039
response to molecule of bacterial origin GO:0002237 194 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.038
amine metabolic process GO:0009308 38 0.037
positive regulation of secretion by cell GO:1903532 128 0.037
single organism carbohydrate metabolic process GO:0044723 118 0.037
sexual reproduction GO:0019953 148 0.037
regulation of cell proliferation GO:0042127 359 0.037
regulation of serine type peptidase activity GO:1902571 1 0.037
cellular amino acid metabolic process GO:0006520 107 0.036
regulation of cellular component organization GO:0051128 368 0.035
response to fatty acid GO:0070542 65 0.034
rna biosynthetic process GO:0032774 380 0.034
vesicle mediated transport GO:0016192 181 0.034
myelination GO:0042552 39 0.034
peptide secretion GO:0002790 86 0.034
regulation of hormone secretion GO:0046883 106 0.034
cellular carbohydrate metabolic process GO:0044262 72 0.033
amide transport GO:0042886 105 0.032
transmission of nerve impulse GO:0019226 42 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
cytoskeleton dependent cytokinesis GO:0061640 2 0.032
regulation of protein metabolic process GO:0051246 289 0.031
circulatory system process GO:0003013 183 0.031
response to organophosphorus GO:0046683 102 0.031
tissue development GO:0009888 252 0.031
cellular amine metabolic process GO:0044106 38 0.031
lipid modification GO:0030258 52 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.031
regulation of synaptic plasticity GO:0048167 70 0.031
carbohydrate homeostasis GO:0033500 75 0.030
blood circulation GO:0008015 183 0.030
peptide transport GO:0015833 97 0.030
single organism reproductive process GO:0044702 297 0.030
cellular chemical homeostasis GO:0055082 247 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
gamete generation GO:0007276 124 0.029
response to glucose GO:0009749 136 0.029
organic acid transport GO:0015849 116 0.029
regulation of cellular localization GO:0060341 263 0.029
hormone secretion GO:0046879 115 0.028
protein processing GO:0016485 68 0.028
positive regulation of extracellular matrix organization GO:1903055 4 0.028
regulation of catalytic activity GO:0050790 304 0.028
positive regulation of cell death GO:0010942 184 0.028
apoptotic process GO:0006915 381 0.027
monocarboxylic acid biosynthetic process GO:0072330 48 0.027
regulation of peptide transport GO:0090087 87 0.027
oxoacid metabolic process GO:0043436 290 0.027
regulation of peptide hormone secretion GO:0090276 80 0.026
peptide hormone secretion GO:0030072 84 0.026
regulation of transcription dna templated GO:0006355 374 0.026
male mating behavior GO:0060179 3 0.026
regulation of peptide secretion GO:0002791 82 0.026
extracellular matrix constituent secretion GO:0070278 4 0.025
negative regulation of signaling GO:0023057 157 0.025
response to glucocorticoid GO:0051384 223 0.025
response to monosaccharide GO:0034284 159 0.025
response to cytokine GO:0034097 215 0.025
response to peptide GO:1901652 292 0.025
cellular response to lipid GO:0071396 201 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
insulin secretion GO:0030073 69 0.025
response to vitamin GO:0033273 131 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
positive regulation of signaling GO:0023056 270 0.024
renal system development GO:0072001 67 0.024
response to ketone GO:1901654 182 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
regulation of insulin secretion GO:0050796 65 0.024
intestinal absorption GO:0050892 3 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.023
cofactor metabolic process GO:0051186 95 0.023
hormone transport GO:0009914 121 0.023
response to acid chemical GO:0001101 222 0.023
response to hexose GO:0009746 144 0.023
ion transmembrane transport GO:0034220 365 0.023
positive regulation of homeostatic process GO:0032846 49 0.023
monocarboxylic acid metabolic process GO:0032787 152 0.023
female pregnancy GO:0007565 122 0.023
regulation of cell differentiation GO:0045595 320 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
proteolysis GO:0006508 175 0.022
cellular modified amino acid metabolic process GO:0006575 61 0.022
regulation of secretion GO:0051046 224 0.022
peptidyl amino acid modification GO:0018193 126 0.022
response to lipopolysaccharide GO:0032496 191 0.022
regulation of neuron projection development GO:0010975 161 0.022
vitamin transport GO:0051180 14 0.022
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.021
liver development GO:0001889 90 0.021
cellular response to cytokine stimulus GO:0071345 127 0.021
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.021
kidney development GO:0001822 67 0.021
regulation of phosphorylation GO:0042325 248 0.021
organic hydroxy compound transport GO:0015850 77 0.021
regulation of rna metabolic process GO:0051252 391 0.021
negative regulation of gene expression GO:0010629 199 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
negative regulation of molecular function GO:0044092 133 0.021
rna metabolic process GO:0016070 406 0.020
cellular response to extracellular stimulus GO:0031668 73 0.020
response to retinoic acid GO:0032526 63 0.020
regulation of blood pressure GO:0008217 83 0.020
response to corticosteroid GO:0031960 235 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
multicellular organismal homeostasis GO:0048871 49 0.020
cellular response to nutrient levels GO:0031669 60 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
fatty acid biosynthetic process GO:0006633 33 0.019
transmembrane transport GO:0055085 412 0.019
regulation of fatty acid metabolic process GO:0019217 18 0.019
regulation of synaptic transmission GO:0050804 141 0.019
neuronal action potential GO:0019228 35 0.019
phospholipid metabolic process GO:0006644 61 0.019
macromolecular complex assembly GO:0065003 273 0.019
organic hydroxy compound metabolic process GO:1901615 115 0.019
positive regulation of triglyceride metabolic process GO:0090208 4 0.019
regulation of activation of jak2 kinase activity GO:0010534 1 0.019
response to mechanical stimulus GO:0009612 134 0.019
response to activity GO:0014823 73 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
epithelial cell differentiation GO:0030855 71 0.019
cation transport GO:0006812 382 0.018
regulation of nervous system development GO:0051960 264 0.018
reproductive structure development GO:0048608 128 0.018
regulation of membrane potential GO:0042391 110 0.018
regulation of transferase activity GO:0051338 123 0.018
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.018
cell cycle GO:0007049 101 0.018
axon ensheathment GO:0008366 40 0.018
negative regulation of peptide hormone secretion GO:0090278 30 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
negative regulation of transport GO:0051051 136 0.018
neuron projection development GO:0031175 273 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
cellular homeostasis GO:0019725 252 0.018
rhythmic process GO:0048511 156 0.018
regulation of protein modification process GO:0031399 194 0.017
ion homeostasis GO:0050801 212 0.017
multicellular organismal signaling GO:0035637 44 0.017
response to vitamin a GO:0033189 36 0.017
cell type specific apoptotic process GO:0097285 134 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
positive regulation of molecular function GO:0044093 230 0.017
negative regulation of catalytic activity GO:0043086 103 0.017
carboxylic acid transport GO:0046942 115 0.017
energy derivation by oxidation of organic compounds GO:0015980 46 0.017
negative regulation of developmental process GO:0051093 125 0.017
activation of jak2 kinase activity GO:0042977 2 0.016
chromosome segregation GO:0007059 2 0.016
generation of precursor metabolites and energy GO:0006091 62 0.016
regulation of extracellular matrix constituent secretion GO:0003330 2 0.016
cellular sodium ion homeostasis GO:0006883 4 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
alcohol metabolic process GO:0006066 77 0.016
regulation of system process GO:0044057 208 0.016
response to starvation GO:0042594 59 0.016
dephosphorylation GO:0016311 98 0.016
lipid transport GO:0006869 61 0.016
regulation of amine transport GO:0051952 54 0.016
response to ethanol GO:0045471 162 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
catenin import into nucleus GO:0035411 1 0.016
negative regulation of cell communication GO:0010648 158 0.016
positive regulation of developmental process GO:0051094 283 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
negative regulation of serine type peptidase activity GO:1902572 1 0.016
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
response to methanol GO:0033986 1 0.016
growth GO:0040007 165 0.016
monosaccharide metabolic process GO:0005996 61 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
negative regulation of secretion GO:0051048 82 0.015
protein phosphorylation GO:0006468 345 0.015
eye morphogenesis GO:0048592 4 0.015
single organism catabolic process GO:0044712 283 0.015
anion transmembrane transport GO:0098656 77 0.015
regulation of hydrolase activity GO:0051336 143 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
neurological system process GO:0050877 219 0.015
regulation of activation of janus kinase activity GO:0010533 1 0.015
response to wounding GO:0009611 254 0.015
response to external biotic stimulus GO:0043207 221 0.015
glycerolipid metabolic process GO:0046486 67 0.015
reproductive system development GO:0061458 128 0.014
nucleic acid templated transcription GO:0097659 379 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
anion transport GO:0006820 178 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
renin angiotensin regulation of aldosterone production GO:0002018 3 0.014
monocarboxylic acid transport GO:0015718 52 0.014
regulation of cell growth GO:0001558 85 0.014
regulation of tube size GO:0035150 89 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
regulation of transcription regulatory region dna binding GO:2000677 4 0.014
cellular component biogenesis GO:0044085 368 0.014
brain renin angiotensin system GO:0002035 3 0.014
cellular cation homeostasis GO:0030003 180 0.014
divalent inorganic cation transport GO:0072511 134 0.014
acyl coa metabolic process GO:0006637 28 0.014
male gamete generation GO:0048232 99 0.014
development of primary sexual characteristics GO:0045137 107 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
erythrocyte differentiation GO:0030218 1 0.014
cellular response to hydroperoxide GO:0071447 2 0.014
positive regulation of peptide hormone secretion GO:0090277 50 0.014
central nervous system development GO:0007417 311 0.014
positive regulation of lipid metabolic process GO:0045834 33 0.014
cation transmembrane transport GO:0098655 263 0.014
response to estrogen GO:0043627 232 0.014
myeloid leukocyte differentiation GO:0002573 20 0.014
regulation of cell development GO:0060284 263 0.014
endocytosis GO:0006897 84 0.014
muscle cell proliferation GO:0033002 84 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
regulation of neuron death GO:1901214 115 0.014
behavior GO:0007610 205 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
jak stat cascade GO:0007259 26 0.013
response to vitamin b6 GO:0034516 1 0.013
regulation of signal transduction GO:0009966 318 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
developmental growth GO:0048589 100 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
cellular response to starvation GO:0009267 27 0.013
negative regulation of hormone secretion GO:0046888 46 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
regulation of neuronal synaptic plasticity GO:0048168 31 0.013
intracellular transport GO:0046907 185 0.013
spermatogenesis GO:0007283 99 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
cell substrate adhesion GO:0031589 29 0.013
sulfur amino acid metabolic process GO:0000096 9 0.013
regulation of neurogenesis GO:0050767 247 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
tube development GO:0035295 89 0.013
sterol homeostasis GO:0055092 3 0.013
regulation of kinase activity GO:0043549 117 0.013
organophosphate biosynthetic process GO:0090407 143 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
regulation of serine type endopeptidase activity GO:1900003 1 0.012
negative regulation of secretion by cell GO:1903531 72 0.012
neuron apoptotic process GO:0051402 88 0.012
cation homeostasis GO:0055080 195 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
organic substance catabolic process GO:1901575 316 0.012
exocytosis GO:0006887 60 0.012
intracellular signal transduction GO:0035556 314 0.012
regulation of anatomical structure size GO:0090066 135 0.012
positive regulation of nervous system development GO:0051962 178 0.012
cellular component assembly GO:0022607 360 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
monocarboxylic acid catabolic process GO:0072329 28 0.012
regulation of blood vessel size GO:0050880 89 0.012
positive regulation of catabolic process GO:0009896 78 0.012
cgmp biosynthetic process GO:0006182 15 0.012
protein maturation GO:0051604 68 0.012
response to cold GO:0009409 29 0.012
heart morphogenesis GO:0003007 3 0.012
regulation of cell projection organization GO:0031344 175 0.012
immune system process GO:0002376 204 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
response to bacterium GO:0009617 200 0.012
protein complex subunit organization GO:0071822 302 0.012
ras protein signal transduction GO:0007265 29 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
artery smooth muscle contraction GO:0014824 4 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
respiratory system process GO:0003016 3 0.011
endoplasmic reticulum organization GO:0007029 1 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.011
cell cell signaling GO:0007267 335 0.011
cardiovascular system development GO:0072358 134 0.011
gastrulation GO:0007369 2 0.011
cell cycle checkpoint GO:0000075 2 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
nucleotide metabolic process GO:0009117 279 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
purine containing compound metabolic process GO:0072521 253 0.011
nucleoside metabolic process GO:0009116 179 0.011
response to oxidative stress GO:0006979 186 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
circulatory system development GO:0072359 134 0.011
glucagon secretion GO:0070091 5 0.011
single organism carbohydrate catabolic process GO:0044724 40 0.011
response to growth factor GO:0070848 189 0.011
blood vessel development GO:0001568 69 0.011
regulation of neuron differentiation GO:0045664 208 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
cell growth GO:0016049 104 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
endomembrane system organization GO:0010256 48 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
sulfur compound metabolic process GO:0006790 70 0.011
ensheathment of neurons GO:0007272 40 0.011
respiratory gaseous exchange GO:0007585 4 0.011
muscle contraction GO:0006936 88 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
purine nucleotide metabolic process GO:0006163 229 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
vascular process in circulatory system GO:0003018 96 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
acute inflammatory response GO:0002526 58 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
regulation of protein kinase activity GO:0045859 105 0.010
gliogenesis GO:0042063 93 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
acetyl coa metabolic process GO:0006084 17 0.010
metal ion transport GO:0030001 289 0.010
ribonucleotide metabolic process GO:0009259 231 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
organelle organization GO:0006996 266 0.010
regulation of ion homeostasis GO:2000021 63 0.010
camera type eye morphogenesis GO:0048593 2 0.010

Thrsp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.044
hypertension DOID:10763 0 0.026
artery disease DOID:0050828 0 0.026
disease of anatomical entity DOID:7 0 0.026
vascular disease DOID:178 0 0.026
essential hypertension DOID:10825 0 0.026
cardiovascular system disease DOID:1287 0 0.026
nervous system disease DOID:863 0 0.014
inherited metabolic disorder DOID:655 0 0.013
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010