Rattus norvegicus

0 known processes

Tifa

TRAF-interacting protein with forkhead-associated domain

(Aliases: T2bp,Ab2-389)

Tifa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 38 0.171
intracellular signal transduction GO:0035556 314 0.171
regulation of fc receptor mediated stimulatory signaling pathway GO:0060368 3 0.123
cellular amino acid metabolic process GO:0006520 107 0.102
regulation of molecular function GO:0065009 398 0.098
peptidyl tyrosine phosphorylation GO:0018108 72 0.097
regulation of signal transduction GO:0009966 318 0.092
regulation of phosphorylation GO:0042325 248 0.091
cellular component assembly GO:0022607 360 0.083
positive regulation of cellular amine metabolic process GO:0033240 3 0.082
positive regulation of phosphate metabolic process GO:0045937 262 0.082
regulation of cellular amino acid metabolic process GO:0006521 2 0.081
regulation of multicellular organismal development GO:2000026 376 0.079
leukocyte cell cell adhesion GO:0007159 4 0.079
protein phosphorylation GO:0006468 345 0.078
rna metabolic process GO:0016070 406 0.075
cellular response to oxygen containing compound GO:1901701 386 0.075
positive regulation of phosphorylation GO:0042327 177 0.073
positive regulation of programmed cell death GO:0043068 157 0.072
immune system process GO:0002376 204 0.067
organophosphate metabolic process GO:0019637 370 0.066
regulation of system process GO:0044057 208 0.066
regulation of protein metabolic process GO:0051246 289 0.065
regulation of phosphorus metabolic process GO:0051174 349 0.064
positive regulation of signal transduction GO:0009967 175 0.063
positive regulation of nervous system development GO:0051962 178 0.063
positive regulation of cell death GO:0010942 184 0.063
cellular amine metabolic process GO:0044106 38 0.062
cellular component biogenesis GO:0044085 368 0.060
positive regulation of protein metabolic process GO:0051247 178 0.057
regulation of intracellular signal transduction GO:1902531 218 0.057
inflammatory response GO:0006954 150 0.056
regulation of cellular ketone metabolic process GO:0010565 27 0.056
reactive nitrogen species metabolic process GO:2001057 1 0.054
immune response activating signal transduction GO:0002757 15 0.054
peptidyl tyrosine modification GO:0018212 72 0.054
regulation of protein phosphorylation GO:0001932 183 0.053
regulation of cellular amine metabolic process GO:0033238 8 0.053
cellular ketone metabolic process GO:0042180 51 0.053
regulation of transcription dna templated GO:0006355 374 0.052
response to inorganic substance GO:0010035 377 0.051
cellular response to acid chemical GO:0071229 75 0.051
regulation of response to stress GO:0080134 126 0.049
regulation of neuron death GO:1901214 115 0.048
carboxylic acid metabolic process GO:0019752 289 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.047
carbohydrate derivative metabolic process GO:1901135 346 0.047
regulation of phosphate metabolic process GO:0019220 349 0.047
blood vessel morphogenesis GO:0048514 58 0.045
protein complex assembly GO:0006461 263 0.045
positive regulation of protein modification process GO:0031401 142 0.045
positive regulation of molecular function GO:0044093 230 0.044
response to decreased oxygen levels GO:0036293 237 0.044
cellular response to stress GO:0033554 269 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.043
programmed cell death GO:0012501 392 0.043
cellular lipid metabolic process GO:0044255 208 0.042
chemical homeostasis GO:0048878 292 0.042
regulation of cell differentiation GO:0045595 320 0.042
reproductive process GO:0022414 372 0.041
regulation of rna metabolic process GO:0051252 391 0.040
response to peptide GO:1901652 292 0.040
regulation of programmed cell death GO:0043067 341 0.039
single organismal cell cell adhesion GO:0016337 42 0.039
carbohydrate metabolic process GO:0005975 130 0.039
nucleic acid templated transcription GO:0097659 379 0.039
macromolecular complex subunit organization GO:0043933 339 0.038
rna biosynthetic process GO:0032774 380 0.038
cellular response to endogenous stimulus GO:0071495 377 0.037
activation of immune response GO:0002253 26 0.037
positive regulation of response to stimulus GO:0048584 285 0.036
regulation of protein modification process GO:0031399 194 0.036
regulation of catalytic activity GO:0050790 304 0.036
nucleotide metabolic process GO:0009117 279 0.036
organic cyclic compound catabolic process GO:1901361 175 0.036
negative regulation of transport GO:0051051 136 0.035
single organism carbohydrate metabolic process GO:0044723 118 0.035
positive regulation of apoptotic process GO:0043065 154 0.035
cellular chemical homeostasis GO:0055082 247 0.034
neurological system process GO:0050877 219 0.034
positive regulation of cellular protein metabolic process GO:0032270 167 0.034
cellular catabolic process GO:0044248 295 0.033
response to biotic stimulus GO:0009607 226 0.033
g protein coupled receptor signaling pathway GO:0007186 242 0.033
organic acid metabolic process GO:0006082 292 0.033
response to nutrient GO:0007584 248 0.033
purine nucleotide metabolic process GO:0006163 229 0.032
apoptotic process GO:0006915 381 0.032
anatomical structure morphogenesis GO:0009653 298 0.031
purine ribonucleotide metabolic process GO:0009150 227 0.031
protein heterooligomerization GO:0051291 89 0.031
regulation of ion transport GO:0043269 245 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.030
transcription dna templated GO:0006351 377 0.030
ribose phosphate metabolic process GO:0019693 235 0.030
macromolecular complex assembly GO:0065003 273 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
regulation of cellular component organization GO:0051128 368 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
homeostatic process GO:0042592 331 0.029
fc receptor mediated stimulatory signaling pathway GO:0002431 3 0.029
metal ion homeostasis GO:0055065 186 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
anion transport GO:0006820 178 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
nitrogen compound transport GO:0071705 229 0.029
positive regulation of signaling GO:0023056 270 0.028
cation transport GO:0006812 382 0.028
regulation of response to wounding GO:1903034 69 0.028
purine nucleoside catabolic process GO:0006152 124 0.028
response to external biotic stimulus GO:0043207 221 0.028
positive regulation of protein phosphorylation GO:0001934 135 0.028
response to ethanol GO:0045471 162 0.028
organic substance catabolic process GO:1901575 316 0.028
response to acid chemical GO:0001101 222 0.028
positive regulation of catalytic activity GO:0043085 184 0.027
nucleoside phosphate catabolic process GO:1901292 140 0.027
response to oxygen levels GO:0070482 265 0.027
brain development GO:0007420 247 0.027
signal transduction by phosphorylation GO:0023014 144 0.027
purine containing compound metabolic process GO:0072521 253 0.027
protein oligomerization GO:0051259 191 0.026
response to metal ion GO:0010038 253 0.026
positive regulation of intracellular signal transduction GO:1902533 138 0.026
cell cell signaling GO:0007267 335 0.026
protein complex subunit organization GO:0071822 302 0.026
transmembrane transport GO:0055085 412 0.025
regulation of cell proliferation GO:0042127 359 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
response to interleukin 1 GO:0070555 55 0.025
regulation of wound healing GO:0061041 14 0.025
cardiovascular system development GO:0072358 134 0.025
mapk cascade GO:0000165 140 0.025
multicellular organism reproduction GO:0032504 233 0.024
regulation of cell development GO:0060284 263 0.024
cognition GO:0050890 92 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
oxoacid metabolic process GO:0043436 290 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
cellular response to cytokine stimulus GO:0071345 127 0.024
neuron death GO:0070997 127 0.024
central nervous system development GO:0007417 311 0.024
regulation of apoptotic process GO:0042981 335 0.023
defense response GO:0006952 194 0.023
positive regulation of response to wounding GO:1903036 34 0.023
cation homeostasis GO:0055080 195 0.023
response to wounding GO:0009611 254 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
response to bacterium GO:0009617 200 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
protein complex biogenesis GO:0070271 263 0.023
cellular response to external stimulus GO:0071496 118 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
single organism biosynthetic process GO:0044711 342 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
regulation of catabolic process GO:0009894 113 0.022
cell activation GO:0001775 97 0.022
blood vessel development GO:0001568 69 0.022
response to extracellular stimulus GO:0009991 380 0.022
organophosphate biosynthetic process GO:0090407 143 0.022
cellular carbohydrate metabolic process GO:0044262 72 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
heterocycle catabolic process GO:0046700 167 0.021
response to alkaloid GO:0043279 132 0.021
regulation of cytokine biosynthetic process GO:0042035 3 0.021
reproduction GO:0000003 245 0.021
cellular homeostasis GO:0019725 252 0.020
regulation of anatomical structure size GO:0090066 135 0.020
response to hypoxia GO:0001666 231 0.020
purine containing compound catabolic process GO:0072523 138 0.020
hormone transport GO:0009914 121 0.020
positive regulation of hydrolase activity GO:0051345 86 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
secretion by cell GO:0032940 248 0.020
single organism reproductive process GO:0044702 297 0.019
cellular protein localization GO:0034613 122 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
regulation of cellular localization GO:0060341 263 0.019
ras protein signal transduction GO:0007265 29 0.019
antigen processing and presentation GO:0019882 2 0.019
negative regulation of metabolic process GO:0009892 331 0.019
metal ion transport GO:0030001 289 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
multi organism reproductive process GO:0044703 262 0.019
regulation of cell activation GO:0050865 50 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
regulation of nervous system development GO:0051960 264 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
cell adhesion GO:0007155 110 0.018
lipid storage GO:0019915 1 0.018
purine ribonucleotide catabolic process GO:0009154 136 0.018
nucleoside catabolic process GO:0009164 126 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
proteolysis GO:0006508 175 0.018
negative regulation of cellular carbohydrate metabolic process GO:0010677 7 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
immunoglobulin mediated immune response GO:0016064 4 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
response to lipopolysaccharide GO:0032496 191 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
positive regulation of cell development GO:0010720 176 0.017
neuron differentiation GO:0030182 368 0.017
olfactory learning GO:0008355 1 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
cytokine biosynthetic process GO:0042089 3 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
cellular response to interleukin 1 GO:0071347 37 0.017
response to nutrient levels GO:0031667 370 0.017
gtp metabolic process GO:0046039 72 0.017
response to hexose GO:0009746 144 0.016
cell projection organization GO:0030030 302 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
organic acid transport GO:0015849 116 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
positive regulation of blood circulation GO:1903524 65 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.016
guanosine containing compound metabolic process GO:1901068 74 0.016
nucleotide catabolic process GO:0009166 139 0.016
jak stat cascade GO:0007259 26 0.016
peptidyl amino acid modification GO:0018193 126 0.016
erk1 and erk2 cascade GO:0070371 48 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
cellular ion homeostasis GO:0006873 184 0.016
gtp catabolic process GO:0006184 71 0.016
alcohol metabolic process GO:0006066 77 0.016
guanosine containing compound catabolic process GO:1901069 71 0.016
regulation of neuron differentiation GO:0045664 208 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
response to glucose GO:0009749 136 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
establishment of protein localization GO:0045184 141 0.015
carbohydrate homeostasis GO:0033500 75 0.015
innate immune response activating signal transduction GO:0002758 9 0.015
regulation of nucleocytoplasmic transport GO:0046822 28 0.015
response to ammonium ion GO:0060359 71 0.015
catabolic process GO:0009056 351 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
aromatic compound catabolic process GO:0019439 168 0.015
response to monosaccharide GO:0034284 159 0.015
learning or memory GO:0007611 90 0.015
oxidation reduction process GO:0055114 304 0.015
sensory perception GO:0007600 101 0.015
ion homeostasis GO:0050801 212 0.015
muscle contraction GO:0006936 88 0.015
cellular response to molecule of bacterial origin GO:0071219 56 0.015
nucleoside triphosphate catabolic process GO:0009143 123 0.015
regulation of protein localization GO:0032880 81 0.015
neuron projection development GO:0031175 273 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
small molecule biosynthetic process GO:0044283 124 0.015
response to peptide hormone GO:0043434 278 0.014
vascular process in circulatory system GO:0003018 96 0.014
negative regulation of signaling GO:0023057 157 0.014
protein transport GO:0015031 132 0.014
pattern recognition receptor signaling pathway GO:0002221 9 0.014
response to ketone GO:1901654 182 0.014
transmission of nerve impulse GO:0019226 42 0.014
positive regulation of gene expression GO:0010628 244 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
secretion GO:0046903 307 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.014
cellular response to lipid GO:0071396 201 0.014
sensory perception of pain GO:0019233 73 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
regulation of mapk cascade GO:0043408 116 0.014
developmental process involved in reproduction GO:0003006 159 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
multi multicellular organism process GO:0044706 138 0.014
response to temperature stimulus GO:0009266 94 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
neuron development GO:0048666 286 0.013
programmed necrotic cell death GO:0097300 2 0.013
response to estrogen GO:0043627 232 0.013
negative regulation of neuron death GO:1901215 69 0.013
multicellular organismal signaling GO:0035637 44 0.013
glial cell differentiation GO:0010001 65 0.013
regulation of protein complex assembly GO:0043254 33 0.013
head development GO:0060322 247 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
olfactory behavior GO:0042048 2 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
regulation of cellular component size GO:0032535 51 0.013
glucose homeostasis GO:0042593 75 0.013
response to oxidative stress GO:0006979 186 0.013
regulation of locomotion GO:0040012 148 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
response to cytokine GO:0034097 215 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
cellular response to peptide GO:1901653 133 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
response to corticosteroid GO:0031960 235 0.013
rho protein signal transduction GO:0007266 11 0.013
muscle system process GO:0003012 115 0.013
response to tumor necrosis factor GO:0034612 56 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
maintenance of location GO:0051235 17 0.013
regulation of blood circulation GO:1903522 110 0.013
chemosensory behavior GO:0007635 2 0.013
regulation of hormone levels GO:0010817 187 0.012
response to peptidoglycan GO:0032494 1 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
protein homooligomerization GO:0051260 91 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
regulation of neuron projection development GO:0010975 161 0.012
protein targeting GO:0006605 61 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
cellular cation homeostasis GO:0030003 180 0.012
positive regulation of cell communication GO:0010647 271 0.012
calcium ion transport GO:0006816 131 0.012
cellular response to tumor necrosis factor GO:0071356 46 0.012
nuclear transport GO:0051169 49 0.012
exocytosis GO:0006887 60 0.012
regulation of blood vessel size GO:0050880 89 0.012
salivary gland development GO:0007431 3 0.012
cytoplasmic transport GO:0016482 115 0.012
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.012
regulation of immune system process GO:0002682 123 0.012
vasoconstriction GO:0042310 54 0.012
action potential GO:0001508 54 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
response to carbohydrate GO:0009743 183 0.012
carboxylic acid transport GO:0046942 115 0.012
regulation of peptide transport GO:0090087 87 0.012
myeloid leukocyte activation GO:0002274 36 0.012
intracellular protein transport GO:0006886 79 0.012
response to mechanical stimulus GO:0009612 134 0.012
positive regulation of angiogenesis GO:0045766 28 0.012
negative regulation of developmental process GO:0051093 125 0.011
response to growth factor GO:0070848 189 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 17 0.011
regulation of cellular extravasation GO:0002691 2 0.011
positive regulation of catabolic process GO:0009896 78 0.011
regulation of secretion by cell GO:1903530 208 0.011
response to other organism GO:0051707 220 0.011
blood circulation GO:0008015 183 0.011
negative regulation of cell death GO:0060548 229 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
negative regulation of gene expression GO:0010629 199 0.011
cellular response to mechanical stimulus GO:0071260 48 0.011
behavior GO:0007610 205 0.011
angiogenesis GO:0001525 53 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
regulation of lymphocyte chemotaxis GO:1901623 1 0.011
response to molecule of fungal origin GO:0002238 3 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
cellular macromolecule localization GO:0070727 122 0.011
toll like receptor signaling pathway GO:0002224 9 0.011
regulation of neurogenesis GO:0050767 247 0.011
single organism catabolic process GO:0044712 283 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
positive regulation of transport GO:0051050 245 0.011
regulation of metal ion transport GO:0010959 118 0.011
immune response GO:0006955 104 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
response to amino acid GO:0043200 75 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.011
regulation of tube size GO:0035150 89 0.011
aging GO:0007568 241 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
negative regulation of cell communication GO:0010648 158 0.010
wound healing GO:0042060 122 0.010
anion transmembrane transport GO:0098656 77 0.010
regulation of response to external stimulus GO:0032101 106 0.010
positive regulation of developmental process GO:0051094 283 0.010
striated muscle contraction GO:0006941 44 0.010
cellular response to lipopolysaccharide GO:0071222 55 0.010
calcium ion homeostasis GO:0055074 162 0.010
organic anion transport GO:0015711 132 0.010
response to glucocorticoid GO:0051384 223 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
cellular response to biotic stimulus GO:0071216 59 0.010
regulation of cytokine production GO:0001817 56 0.010
multicellular organismal homeostasis GO:0048871 49 0.010
positive regulation of tumor necrosis factor production GO:0032760 8 0.010
response to sulfur dioxide GO:0010477 3 0.010
gastrulation GO:0007369 2 0.010
oligopeptide transport GO:0006857 4 0.010
negative regulation of phosphorylation GO:0042326 57 0.010

Tifa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.033
cancer DOID:162 0 0.021
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
eye disease DOID:5614 0 0.017
organ system cancer DOID:0050686 0 0.017