Rattus norvegicus

78 known processes

Tk1

thymidine kinase 1, soluble

(Aliases: Tk)

Tk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna packaging GO:0006323 4 0.136
nucleobase containing small molecule metabolic process GO:0055086 316 0.120
cellular response to stress GO:0033554 269 0.115
regulation of mrna 3 end processing GO:0031440 1 0.110
negative regulation of metabolic process GO:0009892 331 0.106
positive regulation of phosphorus metabolic process GO:0010562 262 0.101
aging GO:0007568 241 0.090
positive regulation of cell proliferation GO:0008284 249 0.089
ribonucleotide metabolic process GO:0009259 231 0.088
positive regulation of developmental process GO:0051094 283 0.087
organelle organization GO:0006996 266 0.082
regulation of multicellular organismal development GO:2000026 376 0.078
alpha amino acid biosynthetic process GO:1901607 23 0.078
regulation of cell proliferation GO:0042127 359 0.073
macromolecular complex subunit organization GO:0043933 339 0.073
cellular response to iron iii ion GO:0071283 3 0.072
positive regulation of phosphate metabolic process GO:0045937 262 0.070
single organism biosynthetic process GO:0044711 342 0.068
actin filament based process GO:0030029 86 0.068
single organism reproductive process GO:0044702 297 0.064
organonitrogen compound biosynthetic process GO:1901566 167 0.062
regulation of cellular component organization GO:0051128 368 0.061
cellular amino acid metabolic process GO:0006520 107 0.058
purine containing compound metabolic process GO:0072521 253 0.057
cellular component assembly GO:0022607 360 0.056
carbohydrate derivative metabolic process GO:1901135 346 0.054
regulation of protein phosphorylation GO:0001932 183 0.054
tetrahydrofolate metabolic process GO:0046653 9 0.053
regulation of phosphorylation GO:0042325 248 0.052
cellular component biogenesis GO:0044085 368 0.052
nucleotide biosynthetic process GO:0009165 98 0.051
organophosphate metabolic process GO:0019637 370 0.050
negative regulation of cellular metabolic process GO:0031324 281 0.050
positive regulation of protein modification process GO:0031401 142 0.049
regulation of protein modification process GO:0031399 194 0.049
cytoskeleton organization GO:0007010 111 0.049
regulation of phosphorus metabolic process GO:0051174 349 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
nucleoside phosphate metabolic process GO:0006753 283 0.048
regulation of molecular function GO:0065009 398 0.046
chromosome segregation GO:0007059 2 0.045
catabolic process GO:0009056 351 0.044
response to wounding GO:0009611 254 0.044
single organism organelle organization GO:1902589 180 0.043
coenzyme metabolic process GO:0006732 86 0.041
nucleoside phosphate biosynthetic process GO:1901293 102 0.041
response to metal ion GO:0010038 253 0.040
regulation of rna metabolic process GO:0051252 391 0.039
positive regulation of signaling GO:0023056 270 0.039
regulation of cell differentiation GO:0045595 320 0.039
cell cycle g1 s phase transition GO:0044843 13 0.038
protein complex assembly GO:0006461 263 0.038
macromolecular complex assembly GO:0065003 273 0.037
organic acid metabolic process GO:0006082 292 0.036
rna metabolic process GO:0016070 406 0.036
positive regulation of cellular protein metabolic process GO:0032270 167 0.036
negative regulation of phosphate metabolic process GO:0045936 80 0.035
nucleoside metabolic process GO:0009116 179 0.035
brain development GO:0007420 247 0.035
ribose phosphate metabolic process GO:0019693 235 0.035
carboxylic acid metabolic process GO:0019752 289 0.034
positive regulation of protein metabolic process GO:0051247 178 0.033
cellular response to oxygen containing compound GO:1901701 386 0.033
positive regulation of cell communication GO:0010647 271 0.033
regulation of kinase activity GO:0043549 117 0.032
single organism catabolic process GO:0044712 283 0.032
cellular chemical homeostasis GO:0055082 247 0.032
protein phosphorylation GO:0006468 345 0.031
organic substance catabolic process GO:1901575 316 0.031
nucleotide metabolic process GO:0009117 279 0.031
positive regulation of multicellular organismal process GO:0051240 387 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
purine ribonucleotide metabolic process GO:0009150 227 0.030
purine containing compound biosynthetic process GO:0072522 85 0.030
response to hypoxia GO:0001666 231 0.030
regulation of protein metabolic process GO:0051246 289 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
response to inorganic substance GO:0010035 377 0.028
reproduction GO:0000003 245 0.028
response to peptide hormone GO:0043434 278 0.028
regulation of nervous system development GO:0051960 264 0.028
regulation of transferase activity GO:0051338 123 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
programmed cell death GO:0012501 392 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
apoptotic process GO:0006915 381 0.027
response to oxygen levels GO:0070482 265 0.027
protein complex subunit organization GO:0071822 302 0.026
regulation of cell development GO:0060284 263 0.026
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.026
ribonucleoside monophosphate metabolic process GO:0009161 88 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
central nervous system development GO:0007417 311 0.025
cell projection organization GO:0030030 302 0.025
muscle cell differentiation GO:0042692 52 0.025
regeneration GO:0031099 163 0.024
neuron development GO:0048666 286 0.024
carbohydrate derivative biosynthetic process GO:1901137 124 0.024
pteridine containing compound metabolic process GO:0042558 14 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
ribonucleoside metabolic process GO:0009119 174 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
positive regulation of protein phosphorylation GO:0001934 135 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
positive regulation of growth GO:0045927 55 0.023
regulation of catalytic activity GO:0050790 304 0.023
mitotic spindle organization GO:0007052 2 0.022
negative regulation of protein metabolic process GO:0051248 114 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
negative regulation of cellular protein metabolic process GO:0032269 106 0.022
purine nucleotide metabolic process GO:0006163 229 0.021
response to radiation GO:0009314 137 0.021
cell cycle checkpoint GO:0000075 2 0.021
nucleoside monophosphate metabolic process GO:0009123 93 0.021
response to peptide GO:1901652 292 0.021
purine containing compound catabolic process GO:0072523 138 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
neurological system process GO:0050877 219 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.020
regulation of signal transduction GO:0009966 318 0.020
neuron differentiation GO:0030182 368 0.019
nucleosome organization GO:0034728 1 0.019
response to ddt GO:0046680 1 0.019
cellular ketone metabolic process GO:0042180 51 0.019
interleukin 1 secretion GO:0050701 3 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
muscle cell proliferation GO:0033002 84 0.018
regulation of protein kinase activity GO:0045859 105 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
response to decreased oxygen levels GO:0036293 237 0.018
amine metabolic process GO:0009308 38 0.018
protein complex biogenesis GO:0070271 263 0.018
alpha amino acid metabolic process GO:1901605 71 0.018
positive regulation of nervous system development GO:0051962 178 0.017
intracellular signal transduction GO:0035556 314 0.017
reproductive process GO:0022414 372 0.017
ribonucleotide biosynthetic process GO:0009260 85 0.017
intracellular transport GO:0046907 185 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
single organism cellular localization GO:1902580 102 0.017
response to extracellular stimulus GO:0009991 380 0.017
regulation of anatomical structure size GO:0090066 135 0.017
regulation of cell projection organization GO:0031344 175 0.017
ras protein signal transduction GO:0007265 29 0.017
centrosome organization GO:0051297 1 0.017
multi organism reproductive process GO:0044703 262 0.017
cellular macromolecule localization GO:0070727 122 0.017
cardiac muscle cell development GO:0055013 16 0.017
positive regulation of organelle organization GO:0010638 48 0.016
dna metabolic process GO:0006259 96 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
regulation of transcription dna templated GO:0006355 374 0.016
cofactor metabolic process GO:0051186 95 0.016
spermatogenesis GO:0007283 99 0.016
folic acid containing compound metabolic process GO:0006760 10 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.016
male gamete generation GO:0048232 99 0.015
positive regulation of cell death GO:0010942 184 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
regulation of neuron projection development GO:0010975 161 0.015
purine nucleoside monophosphate metabolic process GO:0009126 84 0.015
response to glucocorticoid GO:0051384 223 0.015
cell cycle dna replication GO:0044786 1 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
response to ethanol GO:0045471 162 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
male meiosis GO:0007140 1 0.015
negative regulation of gene expression GO:0010629 199 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
heterocycle catabolic process GO:0046700 167 0.015
cellular response to metal ion GO:0071248 55 0.015
meiotic cell cycle process GO:1903046 3 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
muscle tissue development GO:0060537 58 0.015
negative regulation of cell death GO:0060548 229 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
purine ribonucleotide biosynthetic process GO:0009152 81 0.014
muscle structure development GO:0061061 87 0.014
regulation of organelle organization GO:0033043 80 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
neuron projection development GO:0031175 273 0.014
chromatin assembly or disassembly GO:0006333 1 0.014
circulatory system development GO:0072359 134 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
multicellular organism reproduction GO:0032504 233 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of molecular function GO:0044093 230 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
head development GO:0060322 247 0.014
cellular response to peptide GO:1901653 133 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
single organism intracellular transport GO:1902582 166 0.013
positive regulation of transferase activity GO:0051347 81 0.013
cellular amine metabolic process GO:0044106 38 0.013
regulation of meiotic cell cycle GO:0051445 3 0.013
positive regulation of mrna metabolic process GO:1903313 4 0.013
cardiovascular system development GO:0072358 134 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
response to insulin GO:0032868 133 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
response to axon injury GO:0048678 59 0.013
regulation of programmed cell death GO:0043067 341 0.013
negative regulation of microtubule depolymerization GO:0007026 3 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
ion homeostasis GO:0050801 212 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
response to nutrient levels GO:0031667 370 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
growth GO:0040007 165 0.012
cellular protein localization GO:0034613 122 0.012
transcription dna templated GO:0006351 377 0.012
dicarboxylic acid metabolic process GO:0043648 42 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
sexual reproduction GO:0019953 148 0.012
regulation of neuron differentiation GO:0045664 208 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
pyrimidine containing compound metabolic process GO:0072527 20 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
cellular component movement GO:0006928 248 0.012
developmental process involved in reproduction GO:0003006 159 0.011
oxoacid metabolic process GO:0043436 290 0.011
nucleoside catabolic process GO:0009164 126 0.011
microtubule polymerization or depolymerization GO:0031109 13 0.011
tissue development GO:0009888 252 0.011
cellular response to acid chemical GO:0071229 75 0.011
positive regulation of gene expression GO:0010628 244 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
double strand break repair GO:0006302 1 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
establishment of organelle localization GO:0051656 37 0.011
cellular response to lipid GO:0071396 201 0.011
metaphase anaphase transition of cell cycle GO:0044784 1 0.011
negative regulation of nuclear division GO:0051784 1 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
cellular catabolic process GO:0044248 295 0.011
negative regulation of cell division GO:0051782 1 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
gland development GO:0048732 155 0.011
nucleic acid templated transcription GO:0097659 379 0.011
negative regulation of phosphorylation GO:0042326 57 0.011
organophosphate catabolic process GO:0046434 148 0.011
mitotic cell cycle checkpoint GO:0007093 1 0.010
synaptic transmission GO:0007268 235 0.010
positive regulation of synaptic plasticity GO:0031915 3 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
cardiocyte differentiation GO:0035051 22 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.010
homeostatic process GO:0042592 331 0.010

Tk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org