Rattus norvegicus

55 known processes

Tkt

transketolase

Tkt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.719
carboxylic acid metabolic process GO:0019752 289 0.674
cofactor metabolic process GO:0051186 95 0.629
lipid metabolic process GO:0006629 283 0.578
cellular lipid metabolic process GO:0044255 208 0.510
coenzyme metabolic process GO:0006732 86 0.509
single organism carbohydrate metabolic process GO:0044723 118 0.427
organic acid metabolic process GO:0006082 292 0.362
carbohydrate catabolic process GO:0016052 40 0.359
organic substance catabolic process GO:1901575 316 0.357
lipid biosynthetic process GO:0008610 128 0.344
single organism catabolic process GO:0044712 283 0.280
organophosphate metabolic process GO:0019637 370 0.228
single organism carbohydrate catabolic process GO:0044724 40 0.226
monocarboxylic acid metabolic process GO:0032787 152 0.222
fatty acid biosynthetic process GO:0006633 33 0.213
oxoacid metabolic process GO:0043436 290 0.207
carbohydrate metabolic process GO:0005975 130 0.180
nicotinamide nucleotide metabolic process GO:0046496 28 0.172
pentose metabolic process GO:0019321 8 0.171
oxidation reduction process GO:0055114 304 0.163
catabolic process GO:0009056 351 0.158
reproductive process GO:0022414 372 0.139
small molecule biosynthetic process GO:0044283 124 0.138
regulation of cellular component organization GO:0051128 368 0.134
fatty acid metabolic process GO:0006631 99 0.129
sulfur compound metabolic process GO:0006790 70 0.116
acetyl coa metabolic process GO:0006084 17 0.113
response to peptide GO:1901652 292 0.112
acyl coa metabolic process GO:0006637 28 0.099
organic acid biosynthetic process GO:0016053 83 0.097
regulation of lipid metabolic process GO:0019216 68 0.095
response to metal ion GO:0010038 253 0.095
cellular response to hormone stimulus GO:0032870 247 0.081
carboxylic acid biosynthetic process GO:0046394 83 0.080
glucose metabolic process GO:0006006 52 0.076
single organism reproductive process GO:0044702 297 0.076
cellular response to oxygen containing compound GO:1901701 386 0.076
response to oxidative stress GO:0006979 186 0.075
monosaccharide metabolic process GO:0005996 61 0.074
organophosphate biosynthetic process GO:0090407 143 0.073
monocarboxylic acid biosynthetic process GO:0072330 48 0.071
response to glucocorticoid GO:0051384 223 0.066
regulation of cellular catabolic process GO:0031329 101 0.064
negative regulation of metabolic process GO:0009892 331 0.061
Fly
response to peptide hormone GO:0043434 278 0.060
cellular amino acid metabolic process GO:0006520 107 0.057
protein phosphorylation GO:0006468 345 0.057
multicellular organism reproduction GO:0032504 233 0.056
nucleoside phosphate metabolic process GO:0006753 283 0.054
male mating behavior GO:0060179 3 0.052
carbohydrate derivative metabolic process GO:1901135 346 0.050
developmental growth GO:0048589 100 0.050
hexose metabolic process GO:0019318 58 0.049
programmed cell death GO:0012501 392 0.049
pyruvate metabolic process GO:0006090 27 0.045
response to insulin GO:0032868 133 0.045
cellular response to nitrogen compound GO:1901699 210 0.044
intracellular signal transduction GO:0035556 314 0.044
reproduction GO:0000003 245 0.044
response to nutrient GO:0007584 248 0.043
cellular catabolic process GO:0044248 295 0.042
nucleotide metabolic process GO:0009117 279 0.042
cellular response to endogenous stimulus GO:0071495 377 0.042
response to nutrient levels GO:0031667 370 0.041
response to other organism GO:0051707 220 0.041
carbohydrate homeostasis GO:0033500 75 0.040
multi organism reproductive process GO:0044703 262 0.040
positive regulation of cell projection organization GO:0031346 111 0.040
central nervous system development GO:0007417 311 0.039
response to oxygen levels GO:0070482 265 0.039
sexual reproduction GO:0019953 148 0.038
response to ketone GO:1901654 182 0.038
response to hypoxia GO:0001666 231 0.038
pyridine containing compound metabolic process GO:0072524 32 0.038
generation of precursor metabolites and energy GO:0006091 62 0.037
glycogen metabolic process GO:0005977 23 0.037
regulation of hormone levels GO:0010817 187 0.036
development of primary sexual characteristics GO:0045137 107 0.035
response to wounding GO:0009611 254 0.035
positive regulation of developmental process GO:0051094 283 0.035
regulation of phosphate metabolic process GO:0019220 349 0.035
response to ethanol GO:0045471 162 0.035
carbohydrate derivative biosynthetic process GO:1901137 124 0.034
behavior GO:0007610 205 0.034
purine nucleoside triphosphate metabolic process GO:0009144 141 0.034
regulation of apoptotic process GO:0042981 335 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
pentose phosphate shunt GO:0006098 8 0.034
organonitrogen compound biosynthetic process GO:1901566 167 0.034
wound healing GO:0042060 122 0.034
regulation of protein metabolic process GO:0051246 289 0.033
pentose phosphate shunt non oxidative branch GO:0009052 4 0.033
rna metabolic process GO:0016070 406 0.033
Fly
regulation of neuron projection development GO:0010975 161 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.032
Fly
response to inorganic substance GO:0010035 377 0.032
reproductive structure development GO:0048608 128 0.032
cellular ketone metabolic process GO:0042180 51 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
response to estrogen GO:0043627 232 0.031
head development GO:0060322 247 0.031
alcohol metabolic process GO:0006066 77 0.031
regulation of catabolic process GO:0009894 113 0.031
cell type specific apoptotic process GO:0097285 134 0.031
homeostatic process GO:0042592 331 0.031
regulation of organelle organization GO:0033043 80 0.031
regulation of cellular protein metabolic process GO:0032268 267 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.030
steroid biosynthetic process GO:0006694 48 0.030
response to external biotic stimulus GO:0043207 221 0.030
cellular response to peptide hormone stimulus GO:0071375 120 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
ribose phosphate metabolic process GO:0019693 235 0.030
brain development GO:0007420 247 0.030
chemical homeostasis GO:0048878 292 0.029
developmental process involved in reproduction GO:0003006 159 0.029
growth GO:0040007 165 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
regulation of growth GO:0040008 105 0.029
neuron projection development GO:0031175 273 0.029
response to amine GO:0014075 46 0.029
immune system process GO:0002376 204 0.029
tissue development GO:0009888 252 0.029
gamete generation GO:0007276 124 0.029
response to biotic stimulus GO:0009607 226 0.029
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
regulation of lipid biosynthetic process GO:0046890 38 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
response to corticosteroid GO:0031960 235 0.028
glycosyl compound catabolic process GO:1901658 126 0.028
carbohydrate biosynthetic process GO:0016051 42 0.028
response to acid chemical GO:0001101 222 0.028
nadp metabolic process GO:0006739 13 0.027
cellular response to organonitrogen compound GO:0071417 197 0.027
response to toxic substance GO:0009636 133 0.027
response to camp GO:0051591 91 0.027
cellular response to peptide GO:1901653 133 0.027
phospholipid metabolic process GO:0006644 61 0.027
guanosine containing compound metabolic process GO:1901068 74 0.027
immune response GO:0006955 104 0.027
cell projection organization GO:0030030 302 0.027
cellular response to stress GO:0033554 269 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
reproductive system development GO:0061458 128 0.026
alcohol biosynthetic process GO:0046165 38 0.026
synaptic transmission GO:0007268 235 0.025
neuron apoptotic process GO:0051402 88 0.025
regulation of programmed cell death GO:0043067 341 0.025
regulation of immune system process GO:0002682 123 0.025
cellular calcium ion homeostasis GO:0006874 160 0.025
regulation of system process GO:0044057 208 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
Fly
response to cytokine GO:0034097 215 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
regulation of transcription dna templated GO:0006355 374 0.024
Fly
organelle organization GO:0006996 266 0.024
Fly
macromolecule localization GO:0033036 252 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
blood circulation GO:0008015 183 0.024
regulation of cell proliferation GO:0042127 359 0.024
hexose catabolic process GO:0019320 10 0.023
regulation of neuron differentiation GO:0045664 208 0.023
circulatory system development GO:0072359 134 0.023
response to purine containing compound GO:0014074 126 0.022
male gamete generation GO:0048232 99 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
Fly
positive regulation of cell development GO:0010720 176 0.022
response to organophosphorus GO:0046683 102 0.022
monosaccharide catabolic process GO:0046365 10 0.022
response to extracellular stimulus GO:0009991 380 0.022
circulatory system process GO:0003013 183 0.021
cellular amine metabolic process GO:0044106 38 0.021
cation transport GO:0006812 382 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
cellular response to lipid GO:0071396 201 0.021
peptide metabolic process GO:0006518 32 0.021
response to carbohydrate GO:0009743 183 0.021
muscle structure development GO:0061061 87 0.021
cellular carbohydrate metabolic process GO:0044262 72 0.020
regeneration GO:0031099 163 0.020
regulation of membrane potential GO:0042391 110 0.020
cell migration GO:0016477 197 0.020
cellular chemical homeostasis GO:0055082 247 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
spermatogenesis GO:0007283 99 0.020
negative regulation of cell death GO:0060548 229 0.020
amine metabolic process GO:0009308 38 0.020
rna biosynthetic process GO:0032774 380 0.020
Fly
regulation of nervous system development GO:0051960 264 0.020
pyridine nucleotide metabolic process GO:0019362 28 0.019
negative regulation of phosphorus metabolic process GO:0010563 80 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
response to testosterone GO:0033574 55 0.019
gonad development GO:0008406 104 0.019
cellular modified amino acid metabolic process GO:0006575 61 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
single organism intracellular transport GO:1902582 166 0.019
positive regulation of nervous system development GO:0051962 178 0.019
neuron death GO:0070997 127 0.019
response to vitamin GO:0033273 131 0.019
negative regulation of signaling GO:0023057 157 0.019
regulation of protein modification process GO:0031399 194 0.019
negative regulation of gene expression GO:0010629 199 0.019
Fly
regulation of cell development GO:0060284 263 0.019
regulation of catalytic activity GO:0050790 304 0.018
sex differentiation GO:0007548 113 0.018
gland development GO:0048732 155 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
regulation of ion transport GO:0043269 245 0.018
response to reactive oxygen species GO:0000302 120 0.018
response to decreased oxygen levels GO:0036293 237 0.018
metal ion homeostasis GO:0055065 186 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
Fly
regulation of cell projection organization GO:0031344 175 0.018
response to cadmium ion GO:0046686 35 0.017
regulation of signal transduction GO:0009966 318 0.017
response to lipopolysaccharide GO:0032496 191 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
Fly
regulation of transferase activity GO:0051338 123 0.017
nucleoside metabolic process GO:0009116 179 0.017
calcium ion homeostasis GO:0055074 162 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
phospholipid biosynthetic process GO:0008654 29 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
response to estradiol GO:0032355 164 0.017
cellular ion homeostasis GO:0006873 184 0.017
regulation of phosphorylation GO:0042325 248 0.016
cellular cation homeostasis GO:0030003 180 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
cellular response to metal ion GO:0071248 55 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
apoptotic process GO:0006915 381 0.016
negative regulation of molecular function GO:0044092 133 0.016
multicellular organism growth GO:0035264 1 0.016
protein localization GO:0008104 191 0.016
single organism organelle organization GO:1902589 180 0.016
Fly
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
ras protein signal transduction GO:0007265 29 0.015
isoprenoid metabolic process GO:0006720 45 0.015
cellular homeostasis GO:0019725 252 0.015
neuron differentiation GO:0030182 368 0.015
regulation of cell growth GO:0001558 85 0.015
small molecule catabolic process GO:0044282 59 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
ion homeostasis GO:0050801 212 0.015
action potential GO:0001508 54 0.015
heart contraction GO:0060047 57 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
Fly
regulation of molecular function GO:0065009 398 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
positive regulation of immune system process GO:0002684 90 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
cellular component movement GO:0006928 248 0.014
regulation of neurogenesis GO:0050767 247 0.014
regulation of blood pressure GO:0008217 83 0.014
cofactor biosynthetic process GO:0051188 28 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
heart process GO:0003015 57 0.014
lipid modification GO:0030258 52 0.014
regulation of synaptic transmission GO:0050804 141 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
cytoplasmic transport GO:0016482 115 0.014
cell motility GO:0048870 202 0.014
carboxylic acid transport GO:0046942 115 0.014
neuron development GO:0048666 286 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
cell growth GO:0016049 104 0.014
response to radiation GO:0009314 137 0.014
male sex differentiation GO:0046661 64 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
regulation of protein kinase activity GO:0045859 105 0.014
response to disaccharide GO:0034285 10 0.014
anion transport GO:0006820 178 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
organic acid transport GO:0015849 116 0.014
neurological system process GO:0050877 219 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
gtp catabolic process GO:0006184 71 0.014
regulation of cell differentiation GO:0045595 320 0.014
response to fatty acid GO:0070542 65 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
cardiovascular system development GO:0072358 134 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
thioester metabolic process GO:0035383 28 0.013
muscle system process GO:0003012 115 0.013
response to lead ion GO:0010288 33 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
regulation of response to stress GO:0080134 126 0.013
hormone metabolic process GO:0042445 69 0.013
response to bacterium GO:0009617 200 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
localization of cell GO:0051674 202 0.013
metal ion transport GO:0030001 289 0.013
regulation of cellular localization GO:0060341 263 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
gtp metabolic process GO:0046039 72 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
response to retinoic acid GO:0032526 63 0.013
development of primary male sexual characteristics GO:0046546 59 0.013
terpenoid metabolic process GO:0006721 37 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
peptidyl amino acid modification GO:0018193 126 0.013
purine containing compound metabolic process GO:0072521 253 0.013
molting cycle process GO:0022404 2 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
positive regulation of ion transport GO:0043270 94 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
nitrogen compound transport GO:0071705 229 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
regulation of potassium ion transport GO:0043266 29 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
Fly
signal release GO:0023061 145 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of blood circulation GO:1903522 110 0.012
erythrocyte differentiation GO:0030218 1 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
response to sucrose GO:0009744 10 0.012
response to growth factor GO:0070848 189 0.012
glucose homeostasis GO:0042593 75 0.012
response to glucose GO:0009749 136 0.012
telencephalon development GO:0021537 62 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
long chain fatty acid metabolic process GO:0001676 32 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
response to alkaloid GO:0043279 132 0.012
regulation of developmental growth GO:0048638 45 0.012
regulation of cellular response to stress GO:0080135 49 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
defense response GO:0006952 194 0.012
heart morphogenesis GO:0003007 3 0.012
cytoskeleton organization GO:0007010 111 0.012
Fly
nadph regeneration GO:0006740 8 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
purine containing compound catabolic process GO:0072523 138 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
aging GO:0007568 241 0.012
endocrine process GO:0050886 32 0.012
cellular polysaccharide metabolic process GO:0044264 23 0.012
aromatic compound catabolic process GO:0019439 168 0.012
regulation of neuron apoptotic process GO:0043523 83 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
cation homeostasis GO:0055080 195 0.011
macromolecular complex assembly GO:0065003 273 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
cell cycle checkpoint GO:0000075 2 0.011
cellular response to oxygen levels GO:0071453 60 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
Fly
cellular metal ion homeostasis GO:0006875 172 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
nucleoside catabolic process GO:0009164 126 0.011
autophagic cell death GO:0048102 4 0.011
hormone biosynthetic process GO:0042446 25 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
nucleic acid templated transcription GO:0097659 379 0.011
Fly
monosaccharide biosynthetic process GO:0046364 16 0.011
negative regulation of cell communication GO:0010648 158 0.011
regulation of anatomical structure size GO:0090066 135 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
response to amino acid GO:0043200 75 0.011
regulation of secretion GO:0051046 224 0.011
single organism membrane organization GO:0044802 74 0.011
response to monosaccharide GO:0034284 159 0.011
regulation of heart contraction GO:0008016 48 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
autophagy GO:0006914 19 0.011
cell cycle GO:0007049 101 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
cellular amino acid biosynthetic process GO:0008652 32 0.010
positive regulation of kinase activity GO:0033674 77 0.010
muscle cell development GO:0055001 26 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
cytoskeleton dependent cytokinesis GO:0061640 2 0.010
hexose biosynthetic process GO:0019319 15 0.010
nucleotide catabolic process GO:0009166 139 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
cellular response to hypoxia GO:0071456 51 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
energy derivation by oxidation of organic compounds GO:0015980 46 0.010
organic anion transport GO:0015711 132 0.010
energy reserve metabolic process GO:0006112 25 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
icosanoid metabolic process GO:0006690 38 0.010

Tkt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.020
disease of anatomical entity DOID:7 0 0.020
inherited metabolic disorder DOID:655 0 0.020
disease of metabolism DOID:0014667 0 0.020
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
central nervous system disease DOID:331 0 0.011
organ system cancer DOID:0050686 0 0.010
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010