Rattus norvegicus

0 known processes

Tle1

transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)

(Aliases: MGC189561)

Tle1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 379 0.166
Rat
rna biosynthetic process GO:0032774 380 0.115
Rat
rna metabolic process GO:0016070 406 0.107
Rat
regulation of signal transduction GO:0009966 318 0.096
regulation of rna biosynthetic process GO:2001141 381 0.083
Rat
regulation of molecular function GO:0065009 398 0.072
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.068
transcription dna templated GO:0006351 377 0.067
Rat
regulation of phosphate metabolic process GO:0019220 349 0.065
regulation of transcription dna templated GO:0006355 374 0.058
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.057
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.056
transcription from rna polymerase ii promoter GO:0006366 252 0.054
regulation of cellular component organization GO:0051128 368 0.053
positive regulation of cell communication GO:0010647 271 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.052
response to peptide GO:1901652 292 0.047
carboxylic acid metabolic process GO:0019752 289 0.047
positive regulation of biosynthetic process GO:0009891 319 0.043
cellular component assembly GO:0022607 360 0.043
central nervous system development GO:0007417 311 0.043
positive regulation of cellular biosynthetic process GO:0031328 295 0.042
oxoacid metabolic process GO:0043436 290 0.042
regulation of catalytic activity GO:0050790 304 0.041
protein complex biogenesis GO:0070271 263 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.041
organic acid metabolic process GO:0006082 292 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.038
negative regulation of metabolic process GO:0009892 331 0.038
apoptotic process GO:0006915 381 0.037
cellular response to stress GO:0033554 269 0.037
programmed cell death GO:0012501 392 0.036
negative regulation of response to stimulus GO:0048585 155 0.035
positive regulation of phosphate metabolic process GO:0045937 262 0.035
cellular catabolic process GO:0044248 295 0.035
positive regulation of response to stimulus GO:0048584 285 0.035
reproductive process GO:0022414 372 0.035
organophosphate metabolic process GO:0019637 370 0.035
positive regulation of signal transduction GO:0009967 175 0.034
cellular response to growth factor stimulus GO:0071363 162 0.034
catabolic process GO:0009056 351 0.034
positive regulation of signaling GO:0023056 270 0.034
regulation of intracellular signal transduction GO:1902531 218 0.034
response to extracellular stimulus GO:0009991 380 0.033
positive regulation of molecular function GO:0044093 230 0.033
regulation of rna metabolic process GO:0051252 391 0.033
Rat
cellular response to endogenous stimulus GO:0071495 377 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.033
positive regulation of rna metabolic process GO:0051254 203 0.032
homeostatic process GO:0042592 331 0.032
negative regulation of cellular metabolic process GO:0031324 281 0.032
positive regulation of transcription dna templated GO:0045893 197 0.032
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
neuron projection development GO:0031175 273 0.032
regulation of protein modification process GO:0031399 194 0.031
response to nutrient levels GO:0031667 370 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
anatomical structure morphogenesis GO:0009653 298 0.031
response to peptide hormone GO:0043434 278 0.031
cell projection organization GO:0030030 302 0.031
intracellular signal transduction GO:0035556 314 0.031
regulation of canonical wnt signaling pathway GO:0060828 4 0.031
purine containing compound metabolic process GO:0072521 253 0.031
regulation of multicellular organismal development GO:2000026 376 0.030
cellular component biogenesis GO:0044085 368 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
response to growth factor GO:0070848 189 0.030
organic substance catabolic process GO:1901575 316 0.030
neuron differentiation GO:0030182 368 0.029
positive regulation of nucleic acid templated transcription GO:1903508 197 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.028
protein complex subunit organization GO:0071822 302 0.028
cellular amine metabolic process GO:0044106 38 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
regulation of protein metabolic process GO:0051246 289 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
single organism reproductive process GO:0044702 297 0.027
amine metabolic process GO:0009308 38 0.027
protein phosphorylation GO:0006468 345 0.027
cellular component movement GO:0006928 248 0.027
regulation of phosphorylation GO:0042325 248 0.026
regulation of programmed cell death GO:0043067 341 0.026
chemical homeostasis GO:0048878 292 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
regulation of cell differentiation GO:0045595 320 0.026
cellular ketone metabolic process GO:0042180 51 0.026
single organism biosynthetic process GO:0044711 342 0.026
cellular component morphogenesis GO:0032989 155 0.026
negative regulation of rna metabolic process GO:0051253 123 0.026
regulation of neuron differentiation GO:0045664 208 0.025
neuron development GO:0048666 286 0.025
organelle organization GO:0006996 266 0.025
regulation of cellular localization GO:0060341 263 0.025
macromolecular complex subunit organization GO:0043933 339 0.024
protein complex assembly GO:0006461 263 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
negative regulation of cell communication GO:0010648 158 0.024
cellular homeostasis GO:0019725 252 0.024
negative regulation of gene expression GO:0010629 199 0.023
regulation of cell proliferation GO:0042127 359 0.023
regulation of cell development GO:0060284 263 0.023
regulation of neurogenesis GO:0050767 247 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
growth GO:0040007 165 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
response to nutrient GO:0007584 248 0.022
protein localization GO:0008104 191 0.022
single organism organelle organization GO:1902589 180 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
behavior GO:0007610 205 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
regulation of cell projection organization GO:0031344 175 0.021
positive regulation of gene expression GO:0010628 244 0.021
nucleotide metabolic process GO:0009117 279 0.021
positive regulation of developmental process GO:0051094 283 0.021
lipid metabolic process GO:0006629 283 0.021
cellular chemical homeostasis GO:0055082 247 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
cation transport GO:0006812 382 0.021
negative regulation of signaling GO:0023057 157 0.021
positive regulation of protein phosphorylation GO:0001934 135 0.021
response to oxygen levels GO:0070482 265 0.021
single organism behavior GO:0044708 130 0.021
macromolecule localization GO:0033036 252 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
head development GO:0060322 247 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
cell morphogenesis GO:0000902 142 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
neurological system process GO:0050877 219 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
multicellular organism reproduction GO:0032504 233 0.020
intracellular transport GO:0046907 185 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
cell motility GO:0048870 202 0.019
locomotion GO:0040011 237 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
positive regulation of protein modification process GO:0031401 142 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
positive regulation of cell development GO:0010720 176 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
localization of cell GO:0051674 202 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
regulation of catabolic process GO:0009894 113 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
response to inorganic substance GO:0010035 377 0.019
cellular response to peptide hormone stimulus GO:0071375 120 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
reproduction GO:0000003 245 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
protein transport GO:0015031 132 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
regulation of apoptotic process GO:0042981 335 0.018
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
proteolysis GO:0006508 175 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
single organism intracellular transport GO:1902582 166 0.018
cellular lipid metabolic process GO:0044255 208 0.018
multi organism reproductive process GO:0044703 262 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
anion transport GO:0006820 178 0.018
ion homeostasis GO:0050801 212 0.018
regulation of neuron projection development GO:0010975 161 0.018
cellular protein localization GO:0034613 122 0.018
gastrulation GO:0007369 2 0.018
cellular macromolecule localization GO:0070727 122 0.018
ras protein signal transduction GO:0007265 29 0.018
establishment of tissue polarity GO:0007164 2 0.017
reproductive structure development GO:0048608 128 0.017
single organism catabolic process GO:0044712 283 0.017
regulation of proteasomal protein catabolic process GO:0061136 4 0.017
response to decreased oxygen levels GO:0036293 237 0.017
positive regulation of cell death GO:0010942 184 0.017
response to bacterium GO:0009617 200 0.017
regulation of kinase activity GO:0043549 117 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
cation homeostasis GO:0055080 195 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
regulation of nervous system development GO:0051960 264 0.017
response to glucocorticoid GO:0051384 223 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
adult locomotory behavior GO:0008344 4 0.016
metal ion homeostasis GO:0055065 186 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
macromolecular complex assembly GO:0065003 273 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
intracellular protein transport GO:0006886 79 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
cell cell signaling GO:0007267 335 0.016
cell migration GO:0016477 197 0.015
defense response GO:0006952 194 0.015
nitrogen compound transport GO:0071705 229 0.015
brain development GO:0007420 247 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
calcium ion homeostasis GO:0055074 162 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
regulation of stem cell differentiation GO:2000736 2 0.015
cellular ion homeostasis GO:0006873 184 0.015
secretion GO:0046903 307 0.015
tissue development GO:0009888 252 0.015
response to oxidative stress GO:0006979 186 0.015
peptidyl amino acid modification GO:0018193 126 0.015
heart morphogenesis GO:0003007 3 0.015
response to reactive oxygen species GO:0000302 120 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
protein oligomerization GO:0051259 191 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
ribonucleoside catabolic process GO:0042454 126 0.014
cellular response to peptide GO:1901653 133 0.014
synaptic transmission GO:0007268 235 0.014
organophosphate catabolic process GO:0046434 148 0.014
purine containing compound catabolic process GO:0072523 138 0.014
regulation of secretion GO:0051046 224 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
carbohydrate metabolic process GO:0005975 130 0.014
nucleoside metabolic process GO:0009116 179 0.014
regeneration GO:0031099 163 0.014
response to hypoxia GO:0001666 231 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
positive regulation of transport GO:0051050 245 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
negative regulation of developmental process GO:0051093 125 0.014
epithelial cell proliferation GO:0050673 54 0.014
aging GO:0007568 241 0.014
anterior posterior pattern specification GO:0009952 1 0.014
heterocycle catabolic process GO:0046700 167 0.014
negative regulation of cell death GO:0060548 229 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
establishment of protein localization GO:0045184 141 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
cytoskeleton organization GO:0007010 111 0.013
protein targeting GO:0006605 61 0.013
cytoplasmic transport GO:0016482 115 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
regulation of transferase activity GO:0051338 123 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
response to corticosteroid GO:0031960 235 0.013
regulation of membrane potential GO:0042391 110 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
cardiovascular system development GO:0072358 134 0.013
cell projection morphogenesis GO:0048858 123 0.013
regulation of synaptic transmission GO:0050804 141 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
axis specification GO:0009798 4 0.013
cell adhesion GO:0007155 110 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
organic acid transport GO:0015849 116 0.013
regulation of establishment of planar polarity GO:0090175 2 0.013
negative regulation of nervous system development GO:0051961 79 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
sexual reproduction GO:0019953 148 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
regulation of cellular component movement GO:0051270 150 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
regulation of response to stress GO:0080134 126 0.012
double strand break repair GO:0006302 1 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
cellular cation homeostasis GO:0030003 180 0.012
chromosome segregation GO:0007059 2 0.012
response to glucose GO:0009749 136 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
gamete generation GO:0007276 124 0.012
regulation of hormone levels GO:0010817 187 0.012
negative regulation of cell development GO:0010721 82 0.012
regulation of cell migration GO:0030334 128 0.012
regulation of system process GO:0044057 208 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
gonad development GO:0008406 104 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
response to acid chemical GO:0001101 222 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
aromatic compound catabolic process GO:0019439 168 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
gland development GO:0048732 155 0.012
negative regulation of signal transduction GO:0009968 83 0.011
regulation of protein transport GO:0051223 68 0.011
metal ion transport GO:0030001 289 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
response to metal ion GO:0010038 253 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
nucleotide catabolic process GO:0009166 139 0.011
spermatogenesis GO:0007283 99 0.011
peptide transport GO:0015833 97 0.011
biological adhesion GO:0022610 110 0.011
response to toxic substance GO:0009636 133 0.011
hormone secretion GO:0046879 115 0.011
regulation of cell cycle GO:0051726 73 0.011
eye morphogenesis GO:0048592 4 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
dna metabolic process GO:0006259 96 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
signal release GO:0023061 145 0.011
divalent inorganic cation transport GO:0072511 134 0.011
immune system process GO:0002376 204 0.011
response to other organism GO:0051707 220 0.011
response to purine containing compound GO:0014074 126 0.011
epithelium development GO:0060429 96 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
neuron death GO:0070997 127 0.011
gtp metabolic process GO:0046039 72 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
developmental process involved in reproduction GO:0003006 159 0.011
reproductive system development GO:0061458 128 0.011
regulation of hydrolase activity GO:0051336 143 0.011
sex differentiation GO:0007548 113 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
amide transport GO:0042886 105 0.010
regulation of cell motility GO:2000145 131 0.010
cellular response to external stimulus GO:0071496 118 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
response to monosaccharide GO:0034284 159 0.010
regulation of mapk cascade GO:0043408 116 0.010
dephosphorylation GO:0016311 98 0.010
cell part morphogenesis GO:0032990 123 0.010
negative regulation of transport GO:0051051 136 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
positive regulation of catabolic process GO:0009896 78 0.010
nucleoside catabolic process GO:0009164 126 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
non canonical wnt signaling pathway GO:0035567 3 0.010
regulation of protein kinase activity GO:0045859 105 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
respiratory system process GO:0003016 3 0.010
hormone transport GO:0009914 121 0.010
response to carbohydrate GO:0009743 183 0.010
regulation of growth GO:0040008 105 0.010
peptidyl tyrosine modification GO:0018212 72 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
protein homooligomerization GO:0051260 91 0.010
negative regulation of neurogenesis GO:0050768 78 0.010

Tle1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
cardiovascular system disease DOID:1287 0 0.013
musculoskeletal system disease DOID:17 0 0.012
central nervous system disease DOID:331 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011