Rattus norvegicus

237 known processes

Tlr4

toll-like receptor 4

Tlr4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to bacterium GO:0009617 200 0.589
regulation of interleukin 1 secretion GO:0050704 3 0.500
interleukin 1 beta secretion GO:0050702 3 0.494
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.476
myeloid leukocyte activation GO:0002274 36 0.452
response to other organism GO:0051707 220 0.432
immune system process GO:0002376 204 0.422
interleukin 1 secretion GO:0050701 3 0.420
positive regulation of retinal cell programmed cell death GO:0046670 1 0.408
positive regulation of transport GO:0051050 245 0.393
Human
positive regulation of programmed cell death GO:0043068 157 0.333
regulation of defense response GO:0031347 68 0.327
cytokine production GO:0001816 61 0.321
Human Mouse Rat
positive regulation of interleukin 1 secretion GO:0050716 3 0.285
acute inflammatory response to non antigenic stimulus GO:0002525 2 0.284
microglial cell activation GO:0001774 14 0.282
regulation of protein metabolic process GO:0051246 289 0.255
regulation of immune response GO:0050776 55 0.238
regulation of interleukin 1 beta secretion GO:0050706 3 0.228
regulation of secretion GO:0051046 224 0.227
positive regulation of cell death GO:0010942 184 0.203
leukocyte activation GO:0045321 76 0.202
luteolysis GO:0001554 5 0.193
macromolecule localization GO:0033036 252 0.189
Human
regulation of secretion by cell GO:1903530 208 0.186
immune response GO:0006955 104 0.178
defense response GO:0006952 194 0.174
positive regulation of multicellular organismal process GO:0051240 387 0.162
Human Mouse Rat
response to external biotic stimulus GO:0043207 221 0.161
secretion by cell GO:0032940 248 0.161
response to ketone GO:1901654 182 0.158
regulation of neuron apoptotic process GO:0043523 83 0.158
regulation of response to wounding GO:1903034 69 0.156
regulation of programmed cell death GO:0043067 341 0.154
protein secretion GO:0009306 34 0.151
regulation of anatomical structure morphogenesis GO:0022603 141 0.146
response to biotic stimulus GO:0009607 226 0.144
regulation of cellular localization GO:0060341 263 0.138
Human
response to inorganic substance GO:0010035 377 0.138
secretion GO:0046903 307 0.137
regulation of apoptotic process GO:0042981 335 0.134
cell cell signaling GO:0007267 335 0.130
protein transport GO:0015031 132 0.114
Human
inflammatory response GO:0006954 150 0.113
regulation of response to stress GO:0080134 126 0.110
positive regulation of apoptotic process GO:0043065 154 0.108
apoptotic process GO:0006915 381 0.107
regulation of neuron death GO:1901214 115 0.107
regulation of immune system process GO:0002682 123 0.107
response to metal ion GO:0010038 253 0.106
negative regulation of response to stimulus GO:0048585 155 0.106
Mouse
protein localization GO:0008104 191 0.105
Human
positive regulation of response to stimulus GO:0048584 285 0.105
central nervous system development GO:0007417 311 0.104
Rat
hippocampus development GO:0021766 30 0.103
positive regulation of cell development GO:0010720 176 0.101
Rat
single organism behavior GO:0044708 130 0.100
regulation of response to external stimulus GO:0032101 106 0.099
regulation of catalytic activity GO:0050790 304 0.098
Mouse
response to wounding GO:0009611 254 0.096
regulation of multicellular organismal development GO:2000026 376 0.095
Rat
regulation of cytokine secretion GO:0050707 11 0.093
response to oxygen levels GO:0070482 265 0.091
positive regulation of catalytic activity GO:0043085 184 0.091
Mouse
programmed cell death GO:0012501 392 0.089
response to decreased oxygen levels GO:0036293 237 0.087
regulation of cytokine production GO:0001817 56 0.085
Human Mouse Rat
regulation of retinal cell programmed cell death GO:0046668 1 0.084
response to lipopolysaccharide GO:0032496 191 0.082
positive regulation of signaling GO:0023056 270 0.082
Human Mouse
regulation of rna metabolic process GO:0051252 391 0.080
protein heterooligomerization GO:0051291 89 0.078
positive regulation of innate immune response GO:0045089 11 0.076
negative regulation of multicellular organismal process GO:0051241 203 0.076
Mouse
multi organism reproductive process GO:0044703 262 0.076
regulation of system process GO:0044057 208 0.075
response to mechanical stimulus GO:0009612 134 0.075
positive regulation of behavior GO:0048520 38 0.074
regulation of hydrolase activity GO:0051336 143 0.074
neuron apoptotic process GO:0051402 88 0.073
response to transition metal nanoparticle GO:1990267 122 0.073
regulation of cell proliferation GO:0042127 359 0.072
Mouse Rat
positive regulation of cell differentiation GO:0045597 217 0.072
Rat
response to molecule of bacterial origin GO:0002237 194 0.070
cell type specific apoptotic process GO:0097285 134 0.070
regulation of cell development GO:0060284 263 0.070
Rat
response to glucocorticoid GO:0051384 223 0.070
mast cell activation GO:0045576 15 0.069
organic acid metabolic process GO:0006082 292 0.068
positive regulation of secretion GO:0051047 140 0.068
limbic system development GO:0021761 38 0.068
immune response regulating signaling pathway GO:0002764 19 0.067
hormone secretion GO:0046879 115 0.067
positive regulation of cytokine production GO:0001819 42 0.067
Human Mouse Rat
regulation of protein secretion GO:0050708 28 0.066
head development GO:0060322 247 0.065
negative regulation of response to external stimulus GO:0032102 37 0.064
protein phosphorylation GO:0006468 345 0.064
cellular divalent inorganic cation homeostasis GO:0072503 162 0.063
carbohydrate derivative metabolic process GO:1901135 346 0.061
female pregnancy GO:0007565 122 0.061
positive regulation of map kinase activity GO:0043406 46 0.061
Mouse
response to antibiotic GO:0046677 39 0.060
nitrogen compound transport GO:0071705 229 0.060
Human
signal release GO:0023061 145 0.060
response to temperature stimulus GO:0009266 94 0.058
brain development GO:0007420 247 0.058
oxidation reduction process GO:0055114 304 0.058
response to estradiol GO:0032355 164 0.057
regulation of hormone levels GO:0010817 187 0.057
multi multicellular organism process GO:0044706 138 0.056
regulation of cellular protein metabolic process GO:0032268 267 0.056
lymphocyte activation GO:0046649 43 0.056
Mouse
regulation of inflammatory response GO:0050727 48 0.056
divalent metal ion transport GO:0070838 132 0.055
cellular response to organic cyclic compound GO:0071407 202 0.055
synaptic transmission GO:0007268 235 0.055
positive regulation of secretion by cell GO:1903532 128 0.055
response to reactive oxygen species GO:0000302 120 0.055
positive regulation of immune response GO:0050778 42 0.055
localization of cell GO:0051674 202 0.054
establishment of protein localization GO:0045184 141 0.054
Human
circulatory system process GO:0003013 183 0.054
neuron death GO:0070997 127 0.054
pallium development GO:0021543 42 0.054
positive regulation of cellular protein metabolic process GO:0032270 167 0.053
multicellular organismal reproductive process GO:0048609 233 0.052
cation transport GO:0006812 382 0.052
rna metabolic process GO:0016070 406 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.051
Mouse
macrophage activation GO:0042116 15 0.051
regulation of molecular function GO:0065009 398 0.050
positive regulation of molecular function GO:0044093 230 0.050
learning or memory GO:0007611 90 0.050
regulation of synaptic transmission GO:0050804 141 0.050
regulation of cell differentiation GO:0045595 320 0.050
Rat
regulation of cellular component organization GO:0051128 368 0.049
immune effector process GO:0002252 53 0.049
cellular chemical homeostasis GO:0055082 247 0.049
regulation of establishment of protein localization GO:0070201 69 0.048
Human
regulation of cytokine biosynthetic process GO:0042035 3 0.048
Human Mouse
metal ion homeostasis GO:0055065 186 0.048
cellular protein localization GO:0034613 122 0.047
Human
leukocyte activation involved in immune response GO:0002366 16 0.047
Mouse
aging GO:0007568 241 0.046
positive regulation of hydrolase activity GO:0051345 86 0.046
cellular response to molecule of bacterial origin GO:0071219 56 0.046
blood coagulation GO:0007596 26 0.045
Mouse
sensory perception GO:0007600 101 0.045
regulation of cell activation GO:0050865 50 0.045
Mouse
protein complex subunit organization GO:0071822 302 0.045
response to oxidative stress GO:0006979 186 0.044
carboxylic acid metabolic process GO:0019752 289 0.044
cellular component movement GO:0006928 248 0.044
cellular cation homeostasis GO:0030003 180 0.044
negative regulation of cell death GO:0060548 229 0.044
acute inflammatory response GO:0002526 58 0.044
cytosolic calcium ion homeostasis GO:0051480 140 0.044
calcium ion homeostasis GO:0055074 162 0.043
positive regulation of developmental process GO:0051094 283 0.043
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.042
Human Mouse
positive regulation of biosynthetic process GO:0009891 319 0.042
Human Mouse
negative regulation of metabolic process GO:0009892 331 0.042
Mouse
reproductive process GO:0022414 372 0.042
unsaturated fatty acid metabolic process GO:0033559 39 0.041
regulation of lymphocyte chemotaxis GO:1901623 1 0.041
divalent inorganic cation homeostasis GO:0072507 165 0.041
cellular ion homeostasis GO:0006873 184 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.041
cognition GO:0050890 92 0.041
cellular response to oxygen containing compound GO:1901701 386 0.041
nucleoside phosphate metabolic process GO:0006753 283 0.041
negative regulation of response to wounding GO:1903035 23 0.041
single organism cellular localization GO:1902580 102 0.041
Human
sensory perception of pain GO:0019233 73 0.040
negative regulation of programmed cell death GO:0043069 183 0.040
positive regulation of smooth muscle cell migration GO:0014911 27 0.040
response to anoxia GO:0034059 4 0.040
cellular response to lipid GO:0071396 201 0.040
response to toxic substance GO:0009636 133 0.039
cellular ketone metabolic process GO:0042180 51 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
glial cell differentiation GO:0010001 65 0.039
Rat
response to corticosteroid GO:0031960 235 0.039
regulation of protein kinase activity GO:0045859 105 0.039
Mouse
regulation of circadian sleep wake cycle GO:0042749 18 0.038
regeneration GO:0031099 163 0.038
regulation of map kinase activity GO:0043405 53 0.038
Mouse
tonic smooth muscle contraction GO:0014820 4 0.038
ovulation cycle GO:0042698 67 0.038
catabolic process GO:0009056 351 0.037
negative regulation of nervous system development GO:0051961 79 0.037
sequestering of metal ion GO:0051238 9 0.037
oxoacid metabolic process GO:0043436 290 0.037
regulation of lipid metabolic process GO:0019216 68 0.036
positive regulation of immune system process GO:0002684 90 0.036
negative regulation of homeostatic process GO:0032845 47 0.036
gliogenesis GO:0042063 93 0.036
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.036
Mouse
glial cell apoptotic process GO:0034349 8 0.036
regulation of leukocyte activation GO:0002694 45 0.036
Mouse
regulation of membrane potential GO:0042391 110 0.036
cation homeostasis GO:0055080 195 0.036
regulation of neurogenesis GO:0050767 247 0.035
Rat
regulation of transferase activity GO:0051338 123 0.035
Mouse
proteolysis GO:0006508 175 0.035
response to hydrogen peroxide GO:0042542 89 0.035
cellular response to stress GO:0033554 269 0.035
Mouse
organic substance catabolic process GO:1901575 316 0.035
regulation of cellular component movement GO:0051270 150 0.034
response to heat GO:0009408 60 0.034
positive regulation of intracellular signal transduction GO:1902533 138 0.034
Human Mouse
forebrain development GO:0030900 98 0.034
chemical homeostasis GO:0048878 292 0.034
activation of cysteine type endopeptidase activity GO:0097202 4 0.033
cytokine biosynthetic process GO:0042089 3 0.033
Human Mouse
positive regulation of protein metabolic process GO:0051247 178 0.033
response to peptide GO:1901652 292 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.033
positive regulation of protein secretion GO:0050714 19 0.032
regulation of tube size GO:0035150 89 0.032
regulation of t cell migration GO:2000404 1 0.032
positive regulation of protein kinase activity GO:0045860 73 0.032
Mouse
positive regulation of cell communication GO:0010647 271 0.032
Human Mouse
organonitrogen compound biosynthetic process GO:1901566 167 0.032
small gtpase mediated signal transduction GO:0007264 36 0.032
response to gamma radiation GO:0010332 24 0.032
positive regulation of transferase activity GO:0051347 81 0.031
Mouse
lymphocyte migration GO:0072676 3 0.031
positive regulation of protein modification process GO:0031401 142 0.031
hormone transport GO:0009914 121 0.031
peptide biosynthetic process GO:0043043 3 0.031
regulation of signal transduction GO:0009966 318 0.031
Human Mouse
cell activation GO:0001775 97 0.030
sequestering of calcium ion GO:0051208 8 0.030
response to hypoxia GO:0001666 231 0.030
multicellular organism reproduction GO:0032504 233 0.030
cellular catabolic process GO:0044248 295 0.030
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.030
positive regulation of interleukin 1 beta production GO:0032731 6 0.030
regulation of phosphate metabolic process GO:0019220 349 0.029
positive regulation of phosphorylation GO:0042327 177 0.029
cellular response to external stimulus GO:0071496 118 0.029
myeloid cell activation involved in immune response GO:0002275 13 0.028
protein oligomerization GO:0051259 191 0.028
positive regulation of defense response GO:0031349 37 0.028
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.028
regulation of circadian sleep wake cycle sleep GO:0045187 18 0.028
regulation of interleukin 1 beta production GO:0032651 7 0.028
carbohydrate derivative biosynthetic process GO:1901137 124 0.028
regulation of homeostatic process GO:0032844 101 0.028
transcription dna templated GO:0006351 377 0.028
cellular homeostasis GO:0019725 252 0.028
midgut development GO:0007494 13 0.027
nucleic acid templated transcription GO:0097659 379 0.027
regulation of kinase activity GO:0043549 117 0.027
Mouse
innate immune response GO:0045087 35 0.027
locomotion GO:0040011 237 0.027
response to virus GO:0009615 17 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
cell activation involved in immune response GO:0002263 16 0.027
Mouse
rna biosynthetic process GO:0032774 380 0.027
multicellular organismal homeostasis GO:0048871 49 0.027
Mouse
regulation of blood circulation GO:1903522 110 0.027
positive regulation of circadian rhythm GO:0042753 11 0.026
response to cobalt ion GO:0032025 12 0.026
negative regulation of biosynthetic process GO:0009890 168 0.026
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.026
circadian sleep wake cycle GO:0042745 23 0.026
regulation of nervous system development GO:0051960 264 0.026
Rat
cellular response to corticosteroid stimulus GO:0071384 69 0.026
tube development GO:0035295 89 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
organelle organization GO:0006996 266 0.026
regulation of t cell chemotaxis GO:0010819 1 0.026
lens development in camera type eye GO:0002088 13 0.026
g protein coupled receptor signaling pathway GO:0007186 242 0.025
regulation of muscle system process GO:0090257 79 0.025
neuron development GO:0048666 286 0.025
positive regulation of circadian sleep wake cycle sleep GO:0045938 9 0.025
negative regulation of secretion by cell GO:1903531 72 0.025
positive regulation of immune effector process GO:0002699 19 0.025
Mouse
response to cold GO:0009409 29 0.025
wound healing GO:0042060 122 0.025
Mouse
positive regulation of humoral immune response GO:0002922 2 0.025
cellular amine metabolic process GO:0044106 38 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
Mouse
negative regulation of cell communication GO:0010648 158 0.025
Mouse
biological adhesion GO:0022610 110 0.025
heterocycle catabolic process GO:0046700 167 0.025
regulation of monooxygenase activity GO:0032768 8 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
memory GO:0007613 54 0.025
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.024
response to ethanol GO:0045471 162 0.024
cellular response to organonitrogen compound GO:0071417 197 0.024
organophosphate metabolic process GO:0019637 370 0.024
regulation of immune effector process GO:0002697 32 0.024
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.024
Mouse
cellular response to lipopolysaccharide GO:0071222 55 0.024
peptide hormone secretion GO:0030072 84 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
Human Mouse
cellular component assembly GO:0022607 360 0.024
defense response to other organism GO:0098542 17 0.024
Mouse
nucleoside monophosphate metabolic process GO:0009123 93 0.024
response to cytokine GO:0034097 215 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
Mouse
regulation of protein modification process GO:0031399 194 0.023
regulation of endocrine process GO:0044060 21 0.023
regulation of protein transport GO:0051223 68 0.023
Human
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
protein maturation GO:0051604 68 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
gland development GO:0048732 155 0.023
muscle structure development GO:0061061 87 0.023
single organism intracellular transport GO:1902582 166 0.023
Human
regulation of calcium ion transport GO:0051924 77 0.023
negative regulation of cell development GO:0010721 82 0.023
circadian sleep wake cycle process GO:0022410 21 0.023
regulation of neurological system process GO:0031644 43 0.023
positive regulation of cellular component organization GO:0051130 200 0.022
response to hexose GO:0009746 144 0.022
negative regulation of gene expression GO:0010629 199 0.022
telencephalon development GO:0021537 62 0.022
reproduction GO:0000003 245 0.022
regulation of interleukin 6 production GO:0032675 12 0.022
Human Mouse
regulation of acute inflammatory response GO:0002673 23 0.022
female gonad development GO:0008585 53 0.022
ras protein signal transduction GO:0007265 29 0.022
cellular response to steroid hormone stimulus GO:0071383 93 0.022
ribonucleotide catabolic process GO:0009261 136 0.022
positive regulation of t cell migration GO:2000406 1 0.021
muscle cell differentiation GO:0042692 52 0.021
positive regulation of cytokine secretion GO:0050715 9 0.021
purine containing compound metabolic process GO:0072521 253 0.021
regulation of renin secretion into blood stream GO:1900133 1 0.021
negative regulation of cell differentiation GO:0045596 99 0.021
cardiovascular system development GO:0072358 134 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
t cell migration GO:0072678 2 0.021
neurological system process GO:0050877 219 0.021
regulation of locomotion GO:0040012 148 0.021
positive regulation of transcription dna templated GO:0045893 197 0.021
Mouse
female sex differentiation GO:0046660 59 0.021
respiratory system development GO:0060541 45 0.021
hemostasis GO:0007599 26 0.020
Mouse
single organism catabolic process GO:0044712 283 0.020
regulation of synaptic plasticity GO:0048167 70 0.020
retinal cell programmed cell death GO:0046666 1 0.020
regulation of phosphorylation GO:0042325 248 0.020
regulation of protein localization GO:0032880 81 0.020
Human
fatty acid derivative metabolic process GO:1901568 38 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
Mouse
response to estrogen GO:0043627 232 0.020
regulation of cell motility GO:2000145 131 0.020
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.020
cellular response to peptide GO:1901653 133 0.020
regulation of transcription dna templated GO:0006355 374 0.020
response to mineralocorticoid GO:0051385 49 0.020
cytokine secretion GO:0050663 15 0.020
response to testosterone GO:0033574 55 0.020
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.020
single organism biosynthetic process GO:0044711 342 0.019
negative regulation of rna metabolic process GO:0051253 123 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
smooth muscle cell migration GO:0014909 36 0.019
circadian sleep wake cycle sleep GO:0050802 21 0.019
intracellular signal transduction GO:0035556 314 0.019
Human Mouse
cellular component biogenesis GO:0044085 368 0.019
lipid biosynthetic process GO:0008610 128 0.019
cellular lipid metabolic process GO:0044255 208 0.019
ion homeostasis GO:0050801 212 0.019
response to acid chemical GO:0001101 222 0.019
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.019
negative regulation of developmental process GO:0051093 125 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
Mouse
negative regulation of immune system process GO:0002683 39 0.018
response to amino acid GO:0043200 75 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.018
artery smooth muscle contraction GO:0014824 4 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
positive regulation of catabolic process GO:0009896 78 0.018
positive regulation of leukocyte activation GO:0002696 30 0.018
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
Mouse
defense response to virus GO:0051607 9 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
cytosolic calcium ion transport GO:0060401 39 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
respiratory gaseous exchange GO:0007585 4 0.018
negative regulation of defense response GO:0031348 19 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
response to alkaloid GO:0043279 132 0.018
response to carbohydrate GO:0009743 183 0.018
development of primary sexual characteristics GO:0045137 107 0.018
sleep GO:0030431 30 0.017
hepaticobiliary system development GO:0061008 90 0.017
positive regulation of kinase activity GO:0033674 77 0.017
Mouse
fever generation GO:0001660 9 0.017
regulation of blood pressure GO:0008217 83 0.017
positive regulation of ion transport GO:0043270 94 0.017
homeostatic process GO:0042592 331 0.017
Mouse
purine ribonucleotide biosynthetic process GO:0009152 81 0.017
lung development GO:0030324 43 0.017
behavior GO:0007610 205 0.017
regulation of dna metabolic process GO:0051052 60 0.017
intracellular transport GO:0046907 185 0.017
Human
tissue development GO:0009888 252 0.017
negative regulation of secretion GO:0051048 82 0.017
positive regulation of neuron apoptotic process GO:0043525 33 0.017
regulation of muscle contraction GO:0006937 53 0.017
organ regeneration GO:0031100 101 0.017
exocytosis GO:0006887 60 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
regulation of sensory perception of pain GO:0051930 29 0.016
growth GO:0040007 165 0.016
immune response activating signal transduction GO:0002757 15 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
cellular response to metal ion GO:0071248 55 0.016
regulation of interleukin 8 production GO:0032677 2 0.016
Human
negative regulation of protein metabolic process GO:0051248 114 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
blood circulation GO:0008015 183 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
neural crest cell differentiation GO:0014033 2 0.016
response to insulin GO:0032868 133 0.016
multicellular organismal signaling GO:0035637 44 0.016
neuron differentiation GO:0030182 368 0.016
regulation of platelet aggregation GO:0090330 1 0.016
reproductive structure development GO:0048608 128 0.016
nucleoside metabolic process GO:0009116 179 0.016
positive regulation of leukocyte degranulation GO:0043302 4 0.016
spermatogenesis GO:0007283 99 0.016
defense response to gram negative bacterium GO:0050829 3 0.016
Mouse
nucleotide metabolic process GO:0009117 279 0.016
single organism reproductive process GO:0044702 297 0.016
activation of innate immune response GO:0002218 9 0.016
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.015
nucleoside catabolic process GO:0009164 126 0.015
dna metabolic process GO:0006259 96 0.015
negative regulation of cytokine production GO:0001818 16 0.015
Mouse
cytokine metabolic process GO:0042107 6 0.015
Human Mouse
circulatory system development GO:0072359 134 0.015
regulation of ion transport GO:0043269 245 0.015
muscle cell migration GO:0014812 36 0.015
peptide metabolic process GO:0006518 32 0.015
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
negative regulation of molecular function GO:0044092 133 0.015
regulation of leukocyte degranulation GO:0043300 6 0.015
single organism organelle organization GO:1902589 180 0.015
positive regulation of renin secretion into blood stream GO:1900135 1 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
neuron neuron synaptic transmission GO:0007270 60 0.015
actin filament based process GO:0030029 86 0.015
regulation of smooth muscle cell migration GO:0014910 36 0.015
membrane organization GO:0061024 94 0.015
regulation of behavior GO:0050795 61 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.015
developmental process involved in reproduction GO:0003006 159 0.015
negative regulation of sequestering of calcium ion GO:0051283 25 0.015
sex differentiation GO:0007548 113 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
smooth muscle contraction GO:0006939 37 0.015
male gamete generation GO:0048232 99 0.015
regulation of peptidase activity GO:0052547 55 0.015
neural crest cell development GO:0014032 2 0.015
regulation of proteolysis GO:0030162 66 0.015
regulation of peptide transport GO:0090087 87 0.015
Human
n methyl d aspartate receptor clustering GO:0097114 2 0.015
circadian sleep wake cycle non rem sleep GO:0042748 8 0.015
vasculature development GO:0001944 70 0.015
ribonucleoside metabolic process GO:0009119 174 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
Rat
regulation of coagulation GO:0050818 11 0.014
Mouse
calcium ion transport into cytosol GO:0060402 38 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
saliva secretion GO:0046541 3 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
neuronal action potential GO:0019228 35 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
metal ion transport GO:0030001 289 0.014
muscle system process GO:0003012 115 0.014
single organism membrane organization GO:0044802 74 0.014
organic acid transport GO:0015849 116 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
response to glucose GO:0009749 136 0.014

Tlr4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
Human
nervous system disease DOID:863 0 0.033
Human
cancer DOID:162 0 0.022
Human
disease of cellular proliferation DOID:14566 0 0.022
Human
organ system cancer DOID:0050686 0 0.022
Human