Rattus norvegicus

42 known processes

Tlr7

toll-like receptor 7

(Aliases: RGD1563357)

Tlr7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.698
response to biotic stimulus GO:0009607 226 0.529
Human
defense response GO:0006952 194 0.452
response to external biotic stimulus GO:0043207 221 0.378
Human
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.310
positive regulation of cell death GO:0010942 184 0.286
response to bacterium GO:0009617 200 0.279
response to lipopolysaccharide GO:0032496 191 0.234
programmed cell death GO:0012501 392 0.219
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.217
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.217
regulation of immune system process GO:0002682 123 0.196
regulation of cellular protein metabolic process GO:0032268 267 0.196
positive regulation of phosphate metabolic process GO:0045937 262 0.194
regulation of apoptotic process GO:0042981 335 0.186
negative regulation of response to tumor cell GO:0002835 2 0.184
regulation of catalytic activity GO:0050790 304 0.178
response to glucocorticoid GO:0051384 223 0.172
response to nutrient levels GO:0031667 370 0.172
apoptotic process GO:0006915 381 0.172
response to molecule of bacterial origin GO:0002237 194 0.170
negative regulation of immune response to tumor cell GO:0002838 2 0.167
positive regulation of response to stimulus GO:0048584 285 0.166
positive regulation of multicellular organismal process GO:0051240 387 0.165
Human
immune system process GO:0002376 204 0.163
inflammatory response GO:0006954 150 0.160
mapk cascade GO:0000165 140 0.151
positive regulation of molecular function GO:0044093 230 0.148
positive regulation of phosphorylation GO:0042327 177 0.144
cellular lipid metabolic process GO:0044255 208 0.141
cellular response to molecule of bacterial origin GO:0071219 56 0.140
cell activation GO:0001775 97 0.139
organic acid metabolic process GO:0006082 292 0.136
response to corticosteroid GO:0031960 235 0.135
locomotion GO:0040011 237 0.134
response to other organism GO:0051707 220 0.126
Human
regulation of phosphorylation GO:0042325 248 0.122
divalent metal ion transport GO:0070838 132 0.122
positive regulation of intracellular signal transduction GO:1902533 138 0.118
Human
positive regulation of apoptotic process GO:0043065 154 0.118
positive regulation of developmental process GO:0051094 283 0.117
response to oxygen levels GO:0070482 265 0.116
calcium ion transport GO:0006816 131 0.109
metanephric mesenchymal cell migration GO:0035789 2 0.106
organophosphate metabolic process GO:0019637 370 0.105
positive regulation of signaling GO:0023056 270 0.104
Human
response to cytokine GO:0034097 215 0.103
protein phosphorylation GO:0006468 345 0.103
Human
cellular response to lipopolysaccharide GO:0071222 55 0.098
lipid metabolic process GO:0006629 283 0.097
regulation of kinase activity GO:0043549 117 0.095
neuron death GO:0070997 127 0.094
regulation of cellular component organization GO:0051128 368 0.091
regulation of cell differentiation GO:0045595 320 0.090
cellular amino acid metabolic process GO:0006520 107 0.090
positive regulation of phosphorus metabolic process GO:0010562 262 0.089
cellular response to oxygen containing compound GO:1901701 386 0.089
cell motility GO:0048870 202 0.088
carboxylic acid metabolic process GO:0019752 289 0.087
response to toxic substance GO:0009636 133 0.086
regulation of programmed cell death GO:0043067 341 0.084
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.080
cation transport GO:0006812 382 0.080
positive regulation of cell differentiation GO:0045597 217 0.079
regulation of immune response to tumor cell GO:0002837 3 0.078
immune response GO:0006955 104 0.078
positive regulation of protein phosphorylation GO:0001934 135 0.078
regulation of protein metabolic process GO:0051246 289 0.073
Human
regulation of phosphate metabolic process GO:0019220 349 0.071
response to decreased oxygen levels GO:0036293 237 0.068
cellular response to biotic stimulus GO:0071216 59 0.068
positive regulation of cell communication GO:0010647 271 0.068
Human
positive regulation of programmed cell death GO:0043068 157 0.065
myeloid leukocyte activation GO:0002274 36 0.064
positive regulation of protein modification process GO:0031401 142 0.063
regulation of anatomical structure morphogenesis GO:0022603 141 0.063
divalent inorganic cation transport GO:0072511 134 0.062
intracellular signal transduction GO:0035556 314 0.062
Human
regulation of ion transport GO:0043269 245 0.061
response to hypoxia GO:0001666 231 0.060
negative regulation of response to stimulus GO:0048585 155 0.059
regulation of rna metabolic process GO:0051252 391 0.059
response to ketone GO:1901654 182 0.059
negative regulation of cell killing GO:0031342 5 0.058
regulation of cellular ketone metabolic process GO:0010565 27 0.058
negative regulation of innate immune response GO:0045824 4 0.057
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.057
positive regulation of transcription factor import into nucleus GO:0042993 4 0.057
Human
response to extracellular stimulus GO:0009991 380 0.057
positive regulation of protein metabolic process GO:0051247 178 0.057
Human
negative regulation of gene expression GO:0010629 199 0.056
oxoacid metabolic process GO:0043436 290 0.056
response to nutrient GO:0007584 248 0.056
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.055
chemical homeostasis GO:0048878 292 0.055
positive regulation of cellular protein metabolic process GO:0032270 167 0.053
positive regulation of catalytic activity GO:0043085 184 0.052
response to oxidative stress GO:0006979 186 0.051
regulation of protein phosphorylation GO:0001932 183 0.050
b cell activation involved in immune response GO:0002312 1 0.050
regulation of molecular function GO:0065009 398 0.050
response to antibiotic GO:0046677 39 0.049
macrophage chemotaxis GO:0048246 2 0.049
cellular amine metabolic process GO:0044106 38 0.049
sequestering of calcium ion GO:0051208 8 0.047
positive regulation of cell development GO:0010720 176 0.047
regulation of cell development GO:0060284 263 0.047
regulation of cell proliferation GO:0042127 359 0.047
regulation of mapk cascade GO:0043408 116 0.046
regulation of erk1 and erk2 cascade GO:0070372 41 0.046
glial cell differentiation GO:0010001 65 0.046
positive regulation of signal transduction GO:0009967 175 0.046
Human
regulation of nervous system development GO:0051960 264 0.046
establishment of protein localization GO:0045184 141 0.045
Human
calcium ion homeostasis GO:0055074 162 0.045
negative regulation of metabolic process GO:0009892 331 0.045
positive regulation of isotype switching to igg isotypes GO:0048304 1 0.045
positive regulation of transport GO:0051050 245 0.044
Human
single organismal cell cell adhesion GO:0016337 42 0.044
response to ethanol GO:0045471 162 0.044
amine metabolic process GO:0009308 38 0.044
metal ion transport GO:0030001 289 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.044
regulation of response to tumor cell GO:0002834 3 0.043
leukocyte mediated immunity GO:0002443 28 0.043
peptidyl tyrosine phosphorylation GO:0018108 72 0.042
regulation of cellular localization GO:0060341 263 0.042
Human
regulation of b cell differentiation GO:0045577 1 0.042
regulation of hydrolase activity GO:0051336 143 0.042
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.041
cellular response to alcohol GO:0097306 87 0.041
cellular response to endogenous stimulus GO:0071495 377 0.041
cell adhesion GO:0007155 110 0.040
peptidyl amino acid modification GO:0018193 126 0.040
sequestering of metal ion GO:0051238 9 0.040
cellular cation homeostasis GO:0030003 180 0.039
single organism biosynthetic process GO:0044711 342 0.039
cell migration involved in metanephros development GO:0035788 2 0.039
negative regulation of biosynthetic process GO:0009890 168 0.039
regulation of signal transduction GO:0009966 318 0.038
Human
protein complex subunit organization GO:0071822 302 0.038
negative regulation of cell death GO:0060548 229 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
protein localization GO:0008104 191 0.038
Human
cellular response to lipid GO:0071396 201 0.038
macromolecule localization GO:0033036 252 0.037
Human
secretion by cell GO:0032940 248 0.037
glycosaminoglycan biosynthetic process GO:0006024 4 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.036
regulation of protein modification process GO:0031399 194 0.036
neuron projection development GO:0031175 273 0.036
response to inorganic substance GO:0010035 377 0.036
activation of protein kinase activity GO:0032147 47 0.035
leukocyte cell cell adhesion GO:0007159 4 0.035
cellular component assembly GO:0022607 360 0.035
immune effector process GO:0002252 53 0.035
Human
cell migration GO:0016477 197 0.034
positive regulation of neurogenesis GO:0050769 165 0.034
oxidation reduction process GO:0055114 304 0.034
cellular metal ion homeostasis GO:0006875 172 0.034
regulation of response to stress GO:0080134 126 0.034
divalent inorganic cation homeostasis GO:0072507 165 0.034
mast cell activation GO:0045576 15 0.034
gliogenesis GO:0042063 93 0.033
immune response regulating signaling pathway GO:0002764 19 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.033
aging GO:0007568 241 0.033
regulation of transferase activity GO:0051338 123 0.033
regulation of response to external stimulus GO:0032101 106 0.033
aminoglycan biosynthetic process GO:0006023 4 0.032
regulation of hormone levels GO:0010817 187 0.032
negative regulation of phosphate metabolic process GO:0045936 80 0.032
negative regulation of multicellular organismal process GO:0051241 203 0.032
hormone transport GO:0009914 121 0.032
cellular ketone metabolic process GO:0042180 51 0.032
cellular component movement GO:0006928 248 0.032
muscle contraction GO:0006936 88 0.031
regulation of calcium ion transport GO:0051924 77 0.031
regulation of macrophage chemotaxis GO:0010758 2 0.031
cellular chemical homeostasis GO:0055082 247 0.031
immune response to tumor cell GO:0002418 3 0.031
regulation of multicellular organismal development GO:2000026 376 0.030
response to tumor cell GO:0002347 4 0.030
response to reactive oxygen species GO:0000302 120 0.030
biological adhesion GO:0022610 110 0.030
cytosolic calcium ion transport GO:0060401 39 0.030
negative regulation of cell proliferation GO:0008285 119 0.029
ribose phosphate metabolic process GO:0019693 235 0.029
cellular divalent inorganic cation homeostasis GO:0072503 162 0.029
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.029
cytosolic calcium ion homeostasis GO:0051480 140 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.029
positive regulation of fever generation GO:0031622 5 0.029
regulation of immune response GO:0050776 55 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
leukocyte activation involved in immune response GO:0002366 16 0.027
regulation of t cell migration GO:2000404 1 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
regulation of isotype switching to igg isotypes GO:0048302 1 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
regulation of cell growth GO:0001558 85 0.027
protein complex biogenesis GO:0070271 263 0.027
negative regulation of phosphorus metabolic process GO:0010563 80 0.027
peptidyl tyrosine modification GO:0018212 72 0.027
signal transduction by phosphorylation GO:0023014 144 0.027
response to wounding GO:0009611 254 0.026
positive regulation of mapk cascade GO:0043410 92 0.026
hematopoietic progenitor cell differentiation GO:0002244 2 0.026
cellular homeostasis GO:0019725 252 0.026
positive regulation of blood coagulation GO:0030194 4 0.026
muscle system process GO:0003012 115 0.026
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.026
cellular response to cytokine stimulus GO:0071345 127 0.026
response to gamma radiation GO:0010332 24 0.026
cellular response to hormone stimulus GO:0032870 247 0.025
response to peptide hormone GO:0043434 278 0.025
muscle structure development GO:0061061 87 0.025
positive regulation of protein kinase activity GO:0045860 73 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
response to growth factor GO:0070848 189 0.025
rna biosynthetic process GO:0032774 380 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.025
neuronal action potential GO:0019228 35 0.025
neuron development GO:0048666 286 0.025
cation homeostasis GO:0055080 195 0.025
positive regulation of cell proliferation GO:0008284 249 0.024
granulocyte chemotaxis GO:0071621 15 0.024
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.024
Human
positive regulation of kinase activity GO:0033674 77 0.024
regulation of lymphocyte chemotaxis GO:1901623 1 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
regulation of ion homeostasis GO:2000021 63 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
negative regulation of protein metabolic process GO:0051248 114 0.023
positive regulation of inflammatory response GO:0050729 24 0.023
positive regulation of secretion GO:0051047 140 0.023
regulation of protein kinase activity GO:0045859 105 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
cellular calcium ion homeostasis GO:0006874 160 0.023
negative regulation of catalytic activity GO:0043086 103 0.022
positive regulation of intracellular protein transport GO:0090316 20 0.022
Human
regulation of response to wounding GO:1903034 69 0.022
hormone metabolic process GO:0042445 69 0.022
acute inflammatory response GO:0002526 58 0.022
stress activated protein kinase signaling cascade GO:0031098 37 0.022
release of sequestered calcium ion into cytosol GO:0051209 25 0.022
regulation of defense response GO:0031347 68 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
cell growth GO:0016049 104 0.022
lymphocyte chemotaxis GO:0048247 3 0.022
regulation of neurogenesis GO:0050767 247 0.022
lipid biosynthetic process GO:0008610 128 0.022
vesicle mediated transport GO:0016192 181 0.022
platelet activation GO:0030168 8 0.021
s shaped body morphogenesis GO:0072050 2 0.021
catabolic process GO:0009056 351 0.021
regulation of immune effector process GO:0002697 32 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
localization of cell GO:0051674 202 0.021
cellular response to ketone GO:1901655 51 0.021
regulation of fever generation GO:0031620 6 0.021
axon ensheathment GO:0008366 40 0.021
metanephric glomerulus morphogenesis GO:0072275 1 0.021
myeloid leukocyte differentiation GO:0002573 20 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
homeostatic process GO:0042592 331 0.021
neurological system process GO:0050877 219 0.021
positive regulation of transferase activity GO:0051347 81 0.021
positive regulation of hydrolase activity GO:0051345 86 0.021
reactive oxygen species metabolic process GO:0072593 37 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.020
regulation of secretion GO:0051046 224 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.020
single organism intracellular transport GO:1902582 166 0.020
Human
leukocyte activation GO:0045321 76 0.020
tissue development GO:0009888 252 0.020
regulation of acute inflammatory response GO:0002673 23 0.020
secretion GO:0046903 307 0.020
coagulation GO:0050817 28 0.020
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.020
response to dexamethasone GO:0071548 49 0.020
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
regeneration GO:0031099 163 0.019
regulation of inflammatory response GO:0050727 48 0.019
response to heat GO:0009408 60 0.019
cognition GO:0050890 92 0.019
nitrogen compound transport GO:0071705 229 0.019
Human
negative regulation of cellular metabolic process GO:0031324 281 0.019
positive regulation of response to wounding GO:1903036 34 0.019
steroid metabolic process GO:0008202 73 0.019
regulation of cell killing GO:0031341 12 0.019
protein complex assembly GO:0006461 263 0.018
salivary gland development GO:0007431 3 0.018
cellular ion homeostasis GO:0006873 184 0.018
positive regulation of nervous system development GO:0051962 178 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
tube development GO:0035295 89 0.018
response to high density lipoprotein particle GO:0055099 2 0.018
action potential GO:0001508 54 0.018
positive regulation of intracellular transport GO:0032388 39 0.018
Human
protein oligomerization GO:0051259 191 0.018
positive regulation of neuron projection development GO:0010976 99 0.018
regulation of homeostatic process GO:0032844 101 0.018
macromolecular complex assembly GO:0065003 273 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
nucleotide metabolic process GO:0009117 279 0.018
positive regulation of mast cell activation GO:0033005 4 0.017
nucleic acid templated transcription GO:0097659 379 0.017
fatty acid metabolic process GO:0006631 99 0.017
regulation of isotype switching GO:0045191 1 0.017
cellular component morphogenesis GO:0032989 155 0.017
cytokine mediated signaling pathway GO:0019221 43 0.017
chemotaxis GO:0006935 66 0.017
negative regulation of developmental process GO:0051093 125 0.017
leukotriene metabolic process GO:0006691 8 0.017
negative regulation of cell communication GO:0010648 158 0.017
regulation of neuron projection development GO:0010975 161 0.016
growth GO:0040007 165 0.016
calcium ion transport into cytosol GO:0060402 38 0.016
single organism cell adhesion GO:0098602 46 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
positive regulation of gene expression GO:0010628 244 0.016
circulatory system development GO:0072359 134 0.016
b cell differentiation GO:0030183 2 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.016
regulation of neuron differentiation GO:0045664 208 0.016
positive regulation of hemostasis GO:1900048 4 0.016
regulation of growth GO:0040008 105 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
Human
positive regulation of cytoplasmic transport GO:1903651 32 0.016
Human
maintenance of location GO:0051235 17 0.016
cytoplasmic transport GO:0016482 115 0.016
Human
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
t cell chemotaxis GO:0010818 2 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
Human
multicellular organismal homeostasis GO:0048871 49 0.016
negative regulation of transport GO:0051051 136 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
rna metabolic process GO:0016070 406 0.016
negative regulation of immune system process GO:0002683 39 0.015
receptor mediated endocytosis GO:0006898 42 0.015
positive regulation of cell motility GO:2000147 97 0.015
positive regulation of synaptic transmission GO:0050806 62 0.015
ion homeostasis GO:0050801 212 0.015
regulation of intracellular transport GO:0032386 65 0.015
Human
response to vitamin GO:0033273 131 0.015
regulation of sequestering of calcium ion GO:0051282 26 0.015
response to activity GO:0014823 73 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
positive regulation of cell migration GO:0030335 96 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
Human
signal release GO:0023061 145 0.015
reproductive process GO:0022414 372 0.015
innate immune response GO:0045087 35 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
regulation of cell migration GO:0030334 128 0.015
head development GO:0060322 247 0.015
regulation of platelet activation GO:0010543 2 0.015
endoplasmic reticulum to cytosol transport GO:1903513 4 0.015
cellular response to stress GO:0033554 269 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
negative regulation of signaling GO:0023057 157 0.015
dna metabolic process GO:0006259 96 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
hormone secretion GO:0046879 115 0.014
regulation of transcription dna templated GO:0006355 374 0.014
regulation of hormone secretion GO:0046883 106 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
Human
positive regulation of neutrophil migration GO:1902624 6 0.014
multicellular organism growth GO:0035264 1 0.014
respiratory system development GO:0060541 45 0.014
ion transmembrane transport GO:0034220 365 0.014
behavior GO:0007610 205 0.014
positive regulation of immune response GO:0050778 42 0.014
regulation of muscle contraction GO:0006937 53 0.014
response to peptide GO:1901652 292 0.014
response to alkaloid GO:0043279 132 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
neutrophil chemotaxis GO:0030593 11 0.014
regulation of membrane potential GO:0042391 110 0.014
cell type specific apoptotic process GO:0097285 134 0.014
phospholipid metabolic process GO:0006644 61 0.014
negative regulation of neuron death GO:1901215 69 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
chronic inflammatory response GO:0002544 16 0.014
organelle organization GO:0006996 266 0.013
protein transport GO:0015031 132 0.013
Human
regulation of secretion by cell GO:1903530 208 0.013
helper t cell extravasation GO:0035684 1 0.013
response to temperature stimulus GO:0009266 94 0.013
cardiovascular system development GO:0072358 134 0.013
metal ion homeostasis GO:0055065 186 0.013
cytokine secretion GO:0050663 15 0.013
angiogenesis GO:0001525 53 0.013
multi organism reproductive process GO:0044703 262 0.013
rhythmic process GO:0048511 156 0.013
regulation of nucleic acid templated transcription GO:1903506 380 0.013
regulation of b cell mediated immunity GO:0002712 2 0.013
comma shaped body morphogenesis GO:0072049 2 0.013
phospholipase c activating serotonin receptor signaling pathway GO:0007208 2 0.013
regulation of immunoglobulin production GO:0002637 4 0.013
proline transport GO:0015824 3 0.013
metanephric mesenchyme development GO:0072075 2 0.013
response to estrogen GO:0043627 232 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
positive regulation of lipid kinase activity GO:0090218 2 0.013
syncytium formation by plasma membrane fusion GO:0000768 3 0.013
regulation of synaptic transmission GO:0050804 141 0.013
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.012
negative regulation of sequestering of calcium ion GO:0051283 25 0.012
response to glucose GO:0009749 136 0.012
reproduction GO:0000003 245 0.012
regulation of renin secretion into blood stream GO:1900133 1 0.012
regulation of protein localization GO:0032880 81 0.012
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
Human
activation of cysteine type endopeptidase activity GO:0097202 4 0.012
positive regulation of leukocyte degranulation GO:0043302 4 0.012
regulation of cell motility GO:2000145 131 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
urogenital system development GO:0001655 78 0.012
regulation of cell activation GO:0050865 50 0.012
defense response to gram positive bacterium GO:0050830 2 0.012
response to estradiol GO:0032355 164 0.012
positive regulation of ion transport GO:0043270 94 0.012
lymphoid progenitor cell differentiation GO:0002320 2 0.012
single organism organelle organization GO:1902589 180 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
regulation of stress activated mapk cascade GO:0032872 23 0.012
negative regulation of homeostatic process GO:0032845 47 0.012
negative regulation of signal transduction GO:0009968 83 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
negative regulation of molecular function GO:0044092 133 0.012
lung development GO:0030324 43 0.012
intracellular transport GO:0046907 185 0.012
Human
negative regulation of chronic inflammatory response GO:0002677 2 0.012
small gtpase mediated signal transduction GO:0007264 36 0.011
respiratory tube development GO:0030323 43 0.011
regulation of interleukin 12 production GO:0032655 3 0.011
organ regeneration GO:0031100 101 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
microglial cell activation GO:0001774 14 0.011
regulation of metal ion transport GO:0010959 118 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
positive regulation of heat generation GO:0031652 7 0.011
somatic diversification of immunoglobulins involved in immune response GO:0002208 1 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
rho protein signal transduction GO:0007266 11 0.011
central nervous system development GO:0007417 311 0.011
single organism behavior GO:0044708 130 0.011
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 8 0.011
response to carbohydrate GO:0009743 183 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.011
peptide transport GO:0015833 97 0.011
Human
bone remodeling GO:0046849 23 0.011
myeloid cell differentiation GO:0030099 22 0.011
transmission of nerve impulse GO:0019226 42 0.011
purine containing compound metabolic process GO:0072521 253 0.011
vascular endothelial growth factor receptor signaling pathway GO:0048010 8 0.011
striated muscle tissue development GO:0014706 58 0.011
positive regulation of immunoglobulin production GO:0002639 4 0.011
male gamete generation GO:0048232 99 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.010
response to monosaccharide GO:0034284 159 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
saliva secretion GO:0046541 3 0.010
positive regulation of immune system process GO:0002684 90 0.010
positive regulation of dna recombination GO:0045911 1 0.010
response to hexose GO:0009746 144 0.010
response to fatty acid GO:0070542 65 0.010
regulation of muscle system process GO:0090257 79 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
vasculature development GO:0001944 70 0.010
multicellular organism reproduction GO:0032504 233 0.010
exocytosis GO:0006887 60 0.010
bone resorption GO:0045453 18 0.010
cation transmembrane transport GO:0098655 263 0.010

Tlr7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
eye disease DOID:5614 0 0.033
nervous system disease DOID:863 0 0.033
eye and adnexa disease DOID:1492 0 0.033
disease of anatomical entity DOID:7 0 0.033
retinal disease DOID:5679 0 0.033
retinal degeneration DOID:8466 0 0.033
sensory system disease DOID:0050155 0 0.033
disease of cellular proliferation DOID:14566 0 0.026
cancer DOID:162 0 0.026
organ system cancer DOID:0050686 0 0.016
vascular disease DOID:178 0 0.016
artery disease DOID:0050828 0 0.016
cardiovascular system disease DOID:1287 0 0.016