Rattus norvegicus

25 known processes

Tmbim6

transmembrane BAX inhibitor motif containing 6

(Aliases: Ab1-011,Ac1-149,Tegt,Cc1-27)

Tmbim6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid metabolic process GO:0006629 283 0.712
endocytosis GO:0006897 84 0.466
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.409
cellular ion homeostasis GO:0006873 184 0.385
er to golgi vesicle mediated transport GO:0006888 10 0.366
homeostatic process GO:0042592 331 0.305
ion homeostasis GO:0050801 212 0.280
autophagy GO:0006914 19 0.275
single organism catabolic process GO:0044712 283 0.243
cellular lipid metabolic process GO:0044255 208 0.236
regulation of signal transduction GO:0009966 318 0.221
cation homeostasis GO:0055080 195 0.200
vesicle mediated transport GO:0016192 181 0.160
endosome to lysosome transport GO:0008333 6 0.144
nitrogen compound transport GO:0071705 229 0.143
cellular chemical homeostasis GO:0055082 247 0.135
blood circulation GO:0008015 183 0.128
autophagic cell death GO:0048102 4 0.119
regulation of cellular component organization GO:0051128 368 0.118
organelle fusion GO:0048284 17 0.117
chemical homeostasis GO:0048878 292 0.113
single organism intracellular transport GO:1902582 166 0.105
regulation of stem cell differentiation GO:2000736 2 0.101
positive regulation of cell communication GO:0010647 271 0.099
golgi vesicle transport GO:0048193 22 0.097
lipid localization GO:0010876 62 0.092
macromolecule localization GO:0033036 252 0.089
head development GO:0060322 247 0.087
cellular metal ion homeostasis GO:0006875 172 0.087
cellular catabolic process GO:0044248 295 0.086
multicellular organismal homeostasis GO:0048871 49 0.084
response to cytokine GO:0034097 215 0.083
cell projection organization GO:0030030 302 0.079
cellular cation homeostasis GO:0030003 180 0.075
metal ion homeostasis GO:0055065 186 0.072
intracellular signal transduction GO:0035556 314 0.072
single organism membrane organization GO:0044802 74 0.071
hematopoietic progenitor cell differentiation GO:0002244 2 0.069
cell cell signaling GO:0007267 335 0.067
cellular response to stress GO:0033554 269 0.064
carboxylic acid metabolic process GO:0019752 289 0.063
muscle system process GO:0003012 115 0.061
negative regulation of metabolic process GO:0009892 331 0.061
lysosomal transport GO:0007041 8 0.061
muscle structure development GO:0061061 87 0.061
lipid storage GO:0019915 1 0.059
regulation of cell projection organization GO:0031344 175 0.057
anatomical structure morphogenesis GO:0009653 298 0.056
secretion by cell GO:0032940 248 0.056
regulation of neuron projection development GO:0010975 161 0.054
catabolic process GO:0009056 351 0.052
negative regulation of growth GO:0045926 37 0.052
fatty acid transmembrane transport GO:1902001 3 0.051
regulation of protein phosphorylation GO:0001932 183 0.051
regulation of protein metabolic process GO:0051246 289 0.051
establishment of protein localization GO:0045184 141 0.050
regulation of growth GO:0040008 105 0.050
cellular component biogenesis GO:0044085 368 0.049
arf protein signal transduction GO:0032011 0 0.048
organelle inheritance GO:0048308 2 0.047
intracellular transport GO:0046907 185 0.046
single organism organelle organization GO:1902589 180 0.046
enzyme linked receptor protein signaling pathway GO:0007167 116 0.045
neuron differentiation GO:0030182 368 0.045
cytoskeleton organization GO:0007010 111 0.044
positive regulation of response to stimulus GO:0048584 285 0.044
response to metal ion GO:0010038 253 0.044
regulation of neuron differentiation GO:0045664 208 0.044
membrane organization GO:0061024 94 0.043
oxoacid metabolic process GO:0043436 290 0.043
regulation of transcription dna templated GO:0006355 374 0.043
cellular homeostasis GO:0019725 252 0.042
single organism reproductive process GO:0044702 297 0.040
regulation of hormone levels GO:0010817 187 0.040
positive regulation of signaling GO:0023056 270 0.040
sensory organ development GO:0007423 74 0.039
cellular response to hormone stimulus GO:0032870 247 0.039
reproductive process GO:0022414 372 0.039
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.038
protein transport GO:0015031 132 0.038
cell projection morphogenesis GO:0048858 123 0.037
single organism biosynthetic process GO:0044711 342 0.037
protein localization GO:0008104 191 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.036
macroautophagy GO:0016236 4 0.035
sexual reproduction GO:0019953 148 0.035
positive regulation of cellular component organization GO:0051130 200 0.035
regulation of cell differentiation GO:0045595 320 0.035
peptidyl amino acid modification GO:0018193 126 0.035
regulation of nervous system development GO:0051960 264 0.035
growth GO:0040007 165 0.035
cytokinetic process GO:0032506 1 0.034
regulation of cell development GO:0060284 263 0.034
regulation of synaptic transmission GO:0050804 141 0.033
cellular response to starvation GO:0009267 27 0.033
hormone secretion GO:0046879 115 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
organic hydroxy compound metabolic process GO:1901615 115 0.032
organelle assembly GO:0070925 22 0.032
regulation of molecular function GO:0065009 398 0.032
positive regulation of molecular function GO:0044093 230 0.031
regulation of dendrite development GO:0050773 59 0.031
exocytosis GO:0006887 60 0.031
response to inorganic substance GO:0010035 377 0.031
peptide transport GO:0015833 97 0.030
secretion GO:0046903 307 0.030
gamete generation GO:0007276 124 0.030
aging GO:0007568 241 0.029
regulation of lipid storage GO:0010883 1 0.029
regulation of homotypic cell cell adhesion GO:0034110 4 0.029
protein localization to membrane GO:0072657 36 0.029
neuron projection development GO:0031175 273 0.028
cellular component assembly GO:0022607 360 0.028
negative regulation of signaling GO:0023057 157 0.028
positive regulation of cellular protein metabolic process GO:0032270 167 0.028
positive regulation of cell projection organization GO:0031346 111 0.027
response to mechanical stimulus GO:0009612 134 0.027
regulation of lipid metabolic process GO:0019216 68 0.027
brain development GO:0007420 247 0.026
hormone metabolic process GO:0042445 69 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
cellular response to external stimulus GO:0071496 118 0.026
regulation of response to stress GO:0080134 126 0.026
organic acid metabolic process GO:0006082 292 0.025
multicellular organism reproduction GO:0032504 233 0.025
steroid metabolic process GO:0008202 73 0.025
glycerolipid metabolic process GO:0046486 67 0.024
regulation of system process GO:0044057 208 0.024
regulation of hormone secretion GO:0046883 106 0.024
regulation of body fluid levels GO:0050878 90 0.024
response to peptide GO:1901652 292 0.024
nucleic acid templated transcription GO:0097659 379 0.024
organic cyclic compound catabolic process GO:1901361 175 0.024
lipid biosynthetic process GO:0008610 128 0.024
protein complex assembly GO:0006461 263 0.023
neuronal action potential GO:0019228 35 0.023
glycerol 3 phosphate metabolic process GO:0006072 2 0.023
transmembrane transport GO:0055085 412 0.023
protein complex biogenesis GO:0070271 263 0.023
regulation of actin nucleation GO:0051125 2 0.023
maintenance of location GO:0051235 17 0.023
organic acid transport GO:0015849 116 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
regulation of proteasomal protein catabolic process GO:0061136 4 0.023
positive regulation of peptide secretion GO:0002793 52 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
circadian rhythm GO:0007623 88 0.022
cardiac ventricle development GO:0003231 1 0.022
organelle organization GO:0006996 266 0.022
multicellular organismal reproductive process GO:0048609 233 0.021
protein targeting to membrane GO:0006612 11 0.021
neuron development GO:0048666 286 0.021
response to calcium ion GO:0051592 59 0.021
regulation of neurogenesis GO:0050767 247 0.021
regulation of synaptic plasticity GO:0048167 70 0.021
receptor mediated endocytosis GO:0006898 42 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
circadian regulation of gene expression GO:0032922 3 0.020
cellular macromolecule localization GO:0070727 122 0.020
nucleic acid transport GO:0050657 3 0.020
response to peptide hormone GO:0043434 278 0.020
positive regulation of signal transduction GO:0009967 175 0.020
retina development in camera type eye GO:0060041 27 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
positive regulation of lipid metabolic process GO:0045834 33 0.020
carbohydrate metabolic process GO:0005975 130 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
immune system process GO:0002376 204 0.020
protein phosphorylation GO:0006468 345 0.019
camera type eye development GO:0043010 48 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
cellular ketone metabolic process GO:0042180 51 0.019
male gamete generation GO:0048232 99 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
multi organism reproductive process GO:0044703 262 0.019
hormone transport GO:0009914 121 0.019
arp2 3 complex mediated actin nucleation GO:0034314 2 0.019
heart contraction GO:0060047 57 0.018
response to purine containing compound GO:0014074 126 0.018
central nervous system development GO:0007417 311 0.018
early endosome to late endosome transport GO:0045022 2 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
metal ion transport GO:0030001 289 0.017
reproduction GO:0000003 245 0.017
single organism membrane fusion GO:0044801 17 0.017
organic substance catabolic process GO:1901575 316 0.017
phospholipid metabolic process GO:0006644 61 0.017
circulatory system process GO:0003013 183 0.017
signal release GO:0023061 145 0.017
tissue development GO:0009888 252 0.017
amide transport GO:0042886 105 0.017
negative regulation of cell projection organization GO:0031345 50 0.017
chemosensory behavior GO:0007635 2 0.017
neuromuscular process GO:0050905 2 0.017
regulation of angiotensin metabolic process GO:0060177 3 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
regulation of plasma lipoprotein particle levels GO:0097006 3 0.017
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
negative regulation of cell development GO:0010721 82 0.016
regulation of secretion GO:0051046 224 0.016
rna biosynthetic process GO:0032774 380 0.016
biological adhesion GO:0022610 110 0.016
eye development GO:0001654 50 0.016
anion transmembrane transport GO:0098656 77 0.016
positive regulation of glycoprotein metabolic process GO:1903020 3 0.016
response to cgmp GO:0070305 3 0.015
semicircular canal development GO:0060872 1 0.015
cell growth GO:0016049 104 0.015
multicellular organism growth GO:0035264 1 0.015
establishment of vesicle localization GO:0051650 31 0.015
regulation of cell growth GO:0001558 85 0.015
spermatogenesis GO:0007283 99 0.015
response to nutrient levels GO:0031667 370 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.015
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
response to insulin GO:0032868 133 0.015
proteolysis GO:0006508 175 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
developmental growth GO:0048589 100 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
regulation of apoptotic process GO:0042981 335 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
alcohol metabolic process GO:0006066 77 0.014
rna metabolic process GO:0016070 406 0.014
negative regulation of neuron projection development GO:0010977 46 0.014
regulation of protein modification process GO:0031399 194 0.014
anion transport GO:0006820 178 0.014
very long chain fatty acid metabolic process GO:0000038 3 0.014
wound healing GO:0042060 122 0.014
ion transmembrane transport GO:0034220 365 0.014
erythrocyte aggregation GO:0034117 1 0.014
negative regulation of cell communication GO:0010648 158 0.014
negative regulation of molecular function GO:0044092 133 0.014
negative regulation of synaptic transmission GO:0050805 29 0.014
cellular component morphogenesis GO:0032989 155 0.013
macromolecule catabolic process GO:0009057 58 0.013
negative regulation of neuron apoptotic process GO:0043524 45 0.013
regulation of rna metabolic process GO:0051252 391 0.013
positive regulation of transport GO:0051050 245 0.013
response to axon injury GO:0048678 59 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
monocarboxylic acid transport GO:0015718 52 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
rna localization GO:0006403 4 0.013
bone resorption GO:0045453 18 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.013
coagulation GO:0050817 28 0.013
pentose phosphate shunt non oxidative branch GO:0009052 4 0.013
regulation of erythrocyte aggregation GO:0034118 1 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
response to cadmium ion GO:0046686 35 0.013
cell morphogenesis GO:0000902 142 0.013
regulation of kinase activity GO:0043549 117 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
ensheathment of neurons GO:0007272 40 0.013
endocrine process GO:0050886 32 0.012
blood coagulation GO:0007596 26 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
cytoplasmic transport GO:0016482 115 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
tissue homeostasis GO:0001894 28 0.012
steroid biosynthetic process GO:0006694 48 0.012
negative regulation of cell death GO:0060548 229 0.012
cell substrate adhesion GO:0031589 29 0.012
organic anion transport GO:0015711 132 0.012
activation of protein kinase activity GO:0032147 47 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
ras protein signal transduction GO:0007265 29 0.012
developmental process involved in reproduction GO:0003006 159 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
cellular response to nutrient levels GO:0031669 60 0.012
response to ethanol GO:0045471 162 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
response to extracellular stimulus GO:0009991 380 0.012
small molecule biosynthetic process GO:0044283 124 0.012
cell adhesion GO:0007155 110 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
positive regulation of protein modification process GO:0031401 142 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
response to wounding GO:0009611 254 0.012
nucleoside metabolic process GO:0009116 179 0.011
regulation of multicellular organismal development GO:2000026 376 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
aromatic compound catabolic process GO:0019439 168 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
positive regulation of erythrocyte aggregation GO:0034120 1 0.011
response to hexose GO:0009746 144 0.011
antigen processing and presentation of peptide antigen GO:0048002 2 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
response to glucose GO:0009749 136 0.011
cellular protein localization GO:0034613 122 0.011
peptide secretion GO:0002790 86 0.011
negative regulation of phosphorylation GO:0042326 57 0.011
apoptotic process GO:0006915 381 0.011
organic hydroxy compound transport GO:0015850 77 0.011
triglyceride metabolic process GO:0006641 21 0.011
hemostasis GO:0007599 26 0.011
vesicle fusion with golgi apparatus GO:0048280 4 0.011
intracellular protein transport GO:0006886 79 0.011
positive regulation of lipid biosynthetic process GO:0046889 25 0.011
positive regulation of developmental process GO:0051094 283 0.011
positive regulation of lipid kinase activity GO:0090218 2 0.011
dendrite development GO:0016358 72 0.011
cytokine mediated signaling pathway GO:0019221 43 0.011
response to oxidative stress GO:0006979 186 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
negative regulation of nervous system development GO:0051961 79 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
dendritic spine development GO:0060996 20 0.011
transcription dna templated GO:0006351 377 0.011
regulation of anatomical structure size GO:0090066 135 0.011
carboxylic acid transport GO:0046942 115 0.011
autophagic vacuole assembly GO:0000045 4 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
sequestering of calcium ion GO:0051208 8 0.011
action potential GO:0001508 54 0.010
regulation of protein transport GO:0051223 68 0.010
udp glucose metabolic process GO:0006011 3 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
cellular amine metabolic process GO:0044106 38 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
positive regulation of transferase activity GO:0051347 81 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010

Tmbim6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.054
disease of metabolism DOID:0014667 0 0.045
lysosomal storage disease DOID:3211 0 0.028
inherited metabolic disorder DOID:655 0 0.028
sensory system disease DOID:0050155 0 0.019
lipid storage disease DOID:9455 0 0.016
disease of cellular proliferation DOID:14566 0 0.011