Rattus norvegicus

107 known processes

Tnc

tenascin C

Tnc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell motility GO:0048870 202 0.356
cellular response to endogenous stimulus GO:0071495 377 0.288
cell adhesion GO:0007155 110 0.235
regulation of cellular component organization GO:0051128 368 0.178
reproductive process GO:0022414 372 0.176
regulation of cell migration GO:0030334 128 0.176
locomotion GO:0040011 237 0.171
tissue morphogenesis GO:0048729 22 0.165
cellular component movement GO:0006928 248 0.159
cell migration GO:0016477 197 0.156
connective tissue development GO:0061448 33 0.152
response to oxygen levels GO:0070482 265 0.132
multicellular organism reproduction GO:0032504 233 0.127
intracellular signal transduction GO:0035556 314 0.124
positive regulation of response to stimulus GO:0048584 285 0.120
localization of cell GO:0051674 202 0.118
cellular response to hormone stimulus GO:0032870 247 0.117
cellular response to peptide GO:1901653 133 0.116
cellular response to oxygen containing compound GO:1901701 386 0.114
neuron differentiation GO:0030182 368 0.113
axon development GO:0061564 96 0.112
response to nutrient GO:0007584 248 0.111
homeostatic process GO:0042592 331 0.108
ion transmembrane transport GO:0034220 365 0.103
female gonad development GO:0008585 53 0.103
anatomical structure morphogenesis GO:0009653 298 0.098
regulation of molecular function GO:0065009 398 0.093
gastrulation GO:0007369 2 0.092
neuron projection development GO:0031175 273 0.091
tube development GO:0035295 89 0.090
developmental process involved in reproduction GO:0003006 159 0.090
multicellular organismal reproductive process GO:0048609 233 0.089
eye morphogenesis GO:0048592 4 0.089
regulation of nucleic acid templated transcription GO:1903506 380 0.088
regulation of multicellular organismal development GO:2000026 376 0.087
behavior GO:0007610 205 0.082
response to inorganic substance GO:0010035 377 0.081
nucleic acid templated transcription GO:0097659 379 0.081
reproduction GO:0000003 245 0.080
sexual reproduction GO:0019953 148 0.080
apoptotic process GO:0006915 381 0.078
ovulation cycle process GO:0022602 50 0.075
positive regulation of cell migration GO:0030335 96 0.074
regulation of anatomical structure morphogenesis GO:0022603 141 0.073
response to decreased oxygen levels GO:0036293 237 0.073
negative regulation of metabolic process GO:0009892 331 0.072
embryonic skeletal system morphogenesis GO:0048704 3 0.072
immune system process GO:0002376 204 0.072
cellular response to peptide hormone stimulus GO:0071375 120 0.071
positive regulation of transport GO:0051050 245 0.071
negative regulation of developmental process GO:0051093 125 0.070
skeletal system development GO:0001501 41 0.069
programmed cell death GO:0012501 392 0.068
central nervous system development GO:0007417 311 0.066
cellular response to abiotic stimulus GO:0071214 85 0.065
motor neuron axon guidance GO:0008045 1 0.064
cell growth GO:0016049 104 0.064
cellular response to lipid GO:0071396 201 0.064
cellular response to acid chemical GO:0071229 75 0.063
reproductive structure development GO:0048608 128 0.063
biological adhesion GO:0022610 110 0.063
regulation of cellular component movement GO:0051270 150 0.063
cation transmembrane transport GO:0098655 263 0.062
response to extracellular stimulus GO:0009991 380 0.062
neuron projection morphogenesis GO:0048812 122 0.061
cellular component morphogenesis GO:0032989 155 0.060
tube morphogenesis GO:0035239 23 0.060
response to oxidative stress GO:0006979 186 0.058
neuron development GO:0048666 286 0.058
regulation of anatomical structure size GO:0090066 135 0.057
gonad development GO:0008406 104 0.057
formation of primary germ layer GO:0001704 1 0.054
cell morphogenesis GO:0000902 142 0.054
response to heat GO:0009408 60 0.054
renal system development GO:0072001 67 0.054
regulation of transcription dna templated GO:0006355 374 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.051
multi organism reproductive process GO:0044703 262 0.051
response to vitamin GO:0033273 131 0.051
positive regulation of cell motility GO:2000147 97 0.051
response to reactive oxygen species GO:0000302 120 0.050
regulation of programmed cell death GO:0043067 341 0.049
transcription dna templated GO:0006351 377 0.049
morphogenesis of an epithelium GO:0002009 20 0.049
response to growth factor GO:0070848 189 0.048
macromolecular complex subunit organization GO:0043933 339 0.048
blood circulation GO:0008015 183 0.048
regulation of blood circulation GO:1903522 110 0.047
cellular response to cytokine stimulus GO:0071345 127 0.047
regulation of rna biosynthetic process GO:2001141 381 0.045
bone development GO:0060348 25 0.045
growth GO:0040007 165 0.045
development of primary female sexual characteristics GO:0046545 56 0.045
chemical homeostasis GO:0048878 292 0.044
negative regulation of multicellular organismal process GO:0051241 203 0.043
positive regulation of cellular component movement GO:0051272 102 0.043
developmental growth GO:0048589 100 0.043
regulation of cell development GO:0060284 263 0.042
positive regulation of apoptotic process GO:0043065 154 0.042
positive regulation of locomotion GO:0040017 102 0.042
transmembrane transport GO:0055085 412 0.042
single organism reproductive process GO:0044702 297 0.042
cellular response to platelet derived growth factor stimulus GO:0036120 7 0.041
cell part morphogenesis GO:0032990 123 0.041
embryonic skeletal system development GO:0048706 3 0.041
positive regulation of signaling GO:0023056 270 0.041
cell projection organization GO:0030030 302 0.041
positive regulation of developmental process GO:0051094 283 0.041
regulation of system process GO:0044057 208 0.040
regulation of cell motility GO:2000145 131 0.040
organelle organization GO:0006996 266 0.039
regulation of chemotaxis GO:0050920 29 0.039
organic anion transport GO:0015711 132 0.039
rna biosynthetic process GO:0032774 380 0.039
response to cytokine GO:0034097 215 0.039
regulation of cell differentiation GO:0045595 320 0.038
positive regulation of molecular function GO:0044093 230 0.038
cellular response to stress GO:0033554 269 0.038
response to fluid shear stress GO:0034405 16 0.038
muscle structure development GO:0061061 87 0.038
eye development GO:0001654 50 0.038
regulation of phosphorus metabolic process GO:0051174 349 0.037
response to corticosteroid GO:0031960 235 0.037
regulation of tube size GO:0035150 89 0.037
regulation of rna metabolic process GO:0051252 391 0.037
cellular homeostasis GO:0019725 252 0.037
response to wounding GO:0009611 254 0.036
positive regulation of cell death GO:0010942 184 0.036
regulation of cell proliferation GO:0042127 359 0.036
response to nutrient levels GO:0031667 370 0.036
single organism catabolic process GO:0044712 283 0.036
response to metal ion GO:0010038 253 0.035
cellular calcium ion homeostasis GO:0006874 160 0.035
organ morphogenesis GO:0009887 75 0.035
tissue development GO:0009888 252 0.035
regulation of phosphorylation GO:0042325 248 0.034
reproductive system development GO:0061458 128 0.034
response to molecule of bacterial origin GO:0002237 194 0.034
cytosolic calcium ion homeostasis GO:0051480 140 0.034
aging GO:0007568 241 0.034
protein complex biogenesis GO:0070271 263 0.033
response to estradiol GO:0032355 164 0.033
purine nucleotide metabolic process GO:0006163 229 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.033
response to glucocorticoid GO:0051384 223 0.032
positive regulation of cellular component organization GO:0051130 200 0.032
digestive tract development GO:0048565 39 0.032
cellular response to growth factor stimulus GO:0071363 162 0.032
regulation of ion transport GO:0043269 245 0.031
vasculature development GO:0001944 70 0.031
regulation of cell projection organization GO:0031344 175 0.031
response to acid chemical GO:0001101 222 0.031
regulation of locomotion GO:0040012 148 0.031
neurological system process GO:0050877 219 0.031
branching morphogenesis of an epithelial tube GO:0048754 14 0.031
head development GO:0060322 247 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
negative regulation of nervous system development GO:0051961 79 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
cellular ketone metabolic process GO:0042180 51 0.030
odontogenesis GO:0042476 32 0.030
protein complex assembly GO:0006461 263 0.030
appendage morphogenesis GO:0035107 4 0.030
organophosphate metabolic process GO:0019637 370 0.029
skeletal system morphogenesis GO:0048705 12 0.029
cellular response to alcohol GO:0097306 87 0.029
embryo development GO:0009790 49 0.029
positive regulation of cell communication GO:0010647 271 0.029
regulation of phosphate metabolic process GO:0019220 349 0.029
amine metabolic process GO:0009308 38 0.029
cellular response to organonitrogen compound GO:0071417 197 0.029
response to ketone GO:1901654 182 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
limb morphogenesis GO:0035108 4 0.028
response to fibroblast growth factor GO:0071774 29 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.028
b cell differentiation GO:0030183 2 0.027
regulation of signal transduction GO:0009966 318 0.027
metal ion transport GO:0030001 289 0.027
cell projection morphogenesis GO:0048858 123 0.027
wound healing GO:0042060 122 0.027
inorganic cation transmembrane transport GO:0098662 202 0.027
taxis GO:0042330 67 0.026
retinal ganglion cell axon guidance GO:0031290 1 0.026
anatomical structure formation involved in morphogenesis GO:0048646 83 0.026
response to transition metal nanoparticle GO:1990267 122 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
cellular component biogenesis GO:0044085 368 0.025
regulation of apoptotic process GO:0042981 335 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
development of primary sexual characteristics GO:0045137 107 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.025
regulation of cell growth GO:0001558 85 0.025
rna metabolic process GO:0016070 406 0.024
muscle system process GO:0003012 115 0.024
mesonephros development GO:0001823 14 0.024
embryonic cranial skeleton morphogenesis GO:0048701 2 0.024
protein phosphorylation GO:0006468 345 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
protein complex subunit organization GO:0071822 302 0.024
response to hypoxia GO:0001666 231 0.024
cellular catabolic process GO:0044248 295 0.024
positive regulation of immune system process GO:0002684 90 0.024
regulation of catalytic activity GO:0050790 304 0.024
cellular chemical homeostasis GO:0055082 247 0.023
heart morphogenesis GO:0003007 3 0.023
regulation of cytoskeleton organization GO:0051493 49 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.023
proteolysis GO:0006508 175 0.023
gamete generation GO:0007276 124 0.023
response to monosaccharide GO:0034284 159 0.022
epithelium development GO:0060429 96 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
camera type eye development GO:0043010 48 0.022
regulation of blood vessel size GO:0050880 89 0.022
positive regulation of secretion GO:0051047 140 0.022
secretion by cell GO:0032940 248 0.022
single organism behavior GO:0044708 130 0.022
reactive oxygen species metabolic process GO:0072593 37 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
regeneration GO:0031099 163 0.022
negative regulation of cell communication GO:0010648 158 0.022
circulatory system process GO:0003013 183 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
salivary gland morphogenesis GO:0007435 1 0.022
sensory organ development GO:0007423 74 0.022
regulation of nervous system development GO:0051960 264 0.022
negative regulation of signaling GO:0023057 157 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
regulation of cellular localization GO:0060341 263 0.021
macromolecular complex assembly GO:0065003 273 0.021
cellular lipid metabolic process GO:0044255 208 0.021
heart process GO:0003015 57 0.021
cell cycle GO:0007049 101 0.021
chemotaxis GO:0006935 66 0.021
female pregnancy GO:0007565 122 0.021
kidney development GO:0001822 67 0.021
regulation of neurogenesis GO:0050767 247 0.021
defense response GO:0006952 194 0.020
organic acid metabolic process GO:0006082 292 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
ovulation cycle GO:0042698 67 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
cellular response to tumor necrosis factor GO:0071356 46 0.020
anion transport GO:0006820 178 0.020
dna metabolic process GO:0006259 96 0.020
ureteric bud development GO:0001657 14 0.020
response to hyperoxia GO:0055093 45 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
single organismal cell cell adhesion GO:0016337 42 0.019
female sex differentiation GO:0046660 59 0.019
regulation of metal ion transport GO:0010959 118 0.019
multi multicellular organism process GO:0044706 138 0.019
response to hydrogen peroxide GO:0042542 89 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
cellular response to external stimulus GO:0071496 118 0.019
protein autophosphorylation GO:0046777 66 0.019
rhythmic process GO:0048511 156 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
sex differentiation GO:0007548 113 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
regulation of transporter activity GO:0032409 50 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
negative regulation of gene expression GO:0010629 199 0.018
renal system process GO:0003014 40 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
salivary gland development GO:0007431 3 0.018
axis specification GO:0009798 4 0.018
kidney epithelium development GO:0072073 19 0.018
regulation of response to external stimulus GO:0032101 106 0.018
embryonic appendage morphogenesis GO:0035113 4 0.018
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.018
regulation of behavior GO:0050795 61 0.018
cell cell signaling GO:0007267 335 0.017
response to radiation GO:0009314 137 0.017
regulation of neuron projection development GO:0010975 161 0.017
secretion GO:0046903 307 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
axonogenesis GO:0007409 71 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
vascular process in circulatory system GO:0003018 96 0.017
cardiovascular system development GO:0072358 134 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
gliogenesis GO:0042063 93 0.016
response to dexamethasone GO:0071548 49 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
vasoconstriction GO:0042310 54 0.016
heart contraction GO:0060047 57 0.016
regulation of calcium ion transport GO:0051924 77 0.016
regulation of inflammatory response GO:0050727 48 0.016
negative regulation of neuron differentiation GO:0045665 62 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
circulatory system development GO:0072359 134 0.016
response to hexose GO:0009746 144 0.016
retina morphogenesis in camera type eye GO:0060042 1 0.016
embryonic pattern specification GO:0009880 1 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
response to nicotine GO:0035094 51 0.016
cation transport GO:0006812 382 0.016
ovulation GO:0030728 17 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
glycosaminoglycan biosynthetic process GO:0006024 4 0.015
response to purine containing compound GO:0014074 126 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
positive regulation of response to external stimulus GO:0032103 51 0.015
regulation of dna metabolic process GO:0051052 60 0.015
positive regulation of signal transduction GO:0009967 175 0.015
carbohydrate metabolic process GO:0005975 130 0.015
response to glucose GO:0009749 136 0.015
epithelial cell migration GO:0010631 19 0.015
regulation of secretion GO:0051046 224 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
cellular response to interleukin 1 GO:0071347 37 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
cellular response to ketone GO:1901655 51 0.015
calcium ion transport GO:0006816 131 0.015
nucleotide metabolic process GO:0009117 279 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
cellular amine metabolic process GO:0044106 38 0.014
actin filament based process GO:0030029 86 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
oxoacid metabolic process GO:0043436 290 0.014
response to tumor necrosis factor GO:0034612 56 0.014
acute inflammatory response GO:0002526 58 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
response to retinoic acid GO:0032526 63 0.014
catabolic process GO:0009056 351 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
response to other organism GO:0051707 220 0.014
blood vessel morphogenesis GO:0048514 58 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
axon guidance GO:0007411 24 0.014
response to external biotic stimulus GO:0043207 221 0.013
palate development GO:0060021 2 0.013
positive regulation of cell development GO:0010720 176 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
digestive tract morphogenesis GO:0048546 8 0.013
macromolecule localization GO:0033036 252 0.013
carbohydrate homeostasis GO:0033500 75 0.013
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 2 0.013
regulation of protein metabolic process GO:0051246 289 0.013
cellular response to oxygen levels GO:0071453 60 0.013
cartilage development involved in endochondral bone morphogenesis GO:0060351 3 0.013
response to organophosphorus GO:0046683 102 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
response to vitamin e GO:0033197 24 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
embryonic limb morphogenesis GO:0030326 4 0.013
cellular response to carbohydrate stimulus GO:0071322 72 0.013
positive regulation of nervous system development GO:0051962 178 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
regulation of tight junction assembly GO:2000810 2 0.012
skeletal muscle cell differentiation GO:0035914 2 0.012
ameboidal type cell migration GO:0001667 26 0.012
single organism biosynthetic process GO:0044711 342 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
cellular response to metal ion GO:0071248 55 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
response to peptide hormone GO:0043434 278 0.012
response to mechanical stimulus GO:0009612 134 0.012
single organism organelle organization GO:1902589 180 0.012
immune response GO:0006955 104 0.012
neural crest cell migration GO:0001755 1 0.012
regulation of hydrolase activity GO:0051336 143 0.012
camera type eye morphogenesis GO:0048593 2 0.012
ras protein signal transduction GO:0007265 29 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
regulation of cellular component size GO:0032535 51 0.012
regulation of leukocyte migration GO:0002685 24 0.012
epiboly involved in wound healing GO:0090505 2 0.012
regulation of synaptic transmission GO:0050804 141 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
regulation of homeostatic process GO:0032844 101 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
response to ethanol GO:0045471 162 0.012
regulation of hormone levels GO:0010817 187 0.012
regulation of growth GO:0040008 105 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
skin morphogenesis GO:0043589 2 0.012
neuron projection guidance GO:0097485 24 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
muscle cell differentiation GO:0042692 52 0.011
regulation of smooth muscle cell migration GO:0014910 36 0.011
cardiac muscle contraction GO:0060048 27 0.011
cell matrix adhesion GO:0007160 19 0.011
s shaped body morphogenesis GO:0072050 2 0.011
glucose homeostasis GO:0042593 75 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
response to insulin GO:0032868 133 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
multicellular organismal homeostasis GO:0048871 49 0.011
leukocyte migration GO:0050900 38 0.011
spindle organization GO:0007051 2 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
ossification GO:0001503 70 0.011
organic acid transport GO:0015849 116 0.011
positive regulation of chemotaxis GO:0050921 23 0.011
negative regulation of osteoblast differentiation GO:0045668 2 0.011
pro t cell differentiation GO:0002572 1 0.011
brain development GO:0007420 247 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
negative regulation of cell development GO:0010721 82 0.011
positive regulation of gene expression GO:0010628 244 0.011
spermatogenesis GO:0007283 99 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
cardiac ventricle development GO:0003231 1 0.011
digestive system development GO:0055123 41 0.010
response to biotic stimulus GO:0009607 226 0.010
cell type specific apoptotic process GO:0097285 134 0.010
response to lipopolysaccharide GO:0032496 191 0.010
regulation of mapk cascade GO:0043408 116 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
neural crest cell development GO:0014032 2 0.010
metanephric comma shaped body morphogenesis GO:0072278 2 0.010
response to peptide GO:1901652 292 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
phasic smooth muscle contraction GO:0014821 3 0.010

Tnc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.023
sensory system disease DOID:0050155 0 0.023
disease of anatomical entity DOID:7 0 0.023
urinary system disease DOID:18 0 0.012