Rattus norvegicus

204 known processes

Tnf

tumor necrosis factor (TNF superfamily, member 2)

(Aliases: MGC124630,RATTNF,TNF-alpha,Tnfa)

Tnf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.793
response to biotic stimulus GO:0009607 226 0.793
fever generation GO:0001660 9 0.707
Mouse
establishment of protein localization GO:0045184 141 0.704
defense response GO:0006952 194 0.699
cellular response to tumor necrosis factor GO:0071356 46 0.690
Mouse
inflammatory response GO:0006954 150 0.655
response to other organism GO:0051707 220 0.563
neuron death GO:0070997 127 0.562
behavior GO:0007610 205 0.526
positive regulation of signaling GO:0023056 270 0.519
response to cytokine GO:0034097 215 0.512
Mouse
positive regulation of cell death GO:0010942 184 0.501
response to external biotic stimulus GO:0043207 221 0.489
response to tumor necrosis factor GO:0034612 56 0.462
Mouse
response to extracellular stimulus GO:0009991 380 0.459
Rat
anatomical structure morphogenesis GO:0009653 298 0.458
Mouse
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.439
Mouse
positive regulation of intracellular signal transduction GO:1902533 138 0.420
response to lipopolysaccharide GO:0032496 191 0.418
intracellular signal transduction GO:0035556 314 0.401
neuron apoptotic process GO:0051402 88 0.396
regulation of mapk cascade GO:0043408 116 0.367
Mouse
positive regulation of cell communication GO:0010647 271 0.367
protein localization GO:0008104 191 0.365
cellular response to lipid GO:0071396 201 0.364
Mouse
response to nutrient GO:0007584 248 0.362
Rat
protein transport GO:0015031 132 0.351
response to alkaloid GO:0043279 132 0.340
immune system process GO:0002376 204 0.332
Zebrafish Mouse Rat
regulation of neuron apoptotic process GO:0043523 83 0.327
macromolecule localization GO:0033036 252 0.317
positive regulation of programmed cell death GO:0043068 157 0.309
circulatory system process GO:0003013 183 0.288
single organism behavior GO:0044708 130 0.287
response to temperature stimulus GO:0009266 94 0.286
granulocyte migration GO:0097530 16 0.285
positive regulation of transport GO:0051050 245 0.272
regulation of immune system process GO:0002682 123 0.264
Mouse Rat
positive regulation of multicellular organismal process GO:0051240 387 0.261
apoptotic process GO:0006915 381 0.260
acute inflammatory response GO:0002526 58 0.259
Mouse
regulation of anatomical structure morphogenesis GO:0022603 141 0.257
Mouse
regulation of immunoglobulin secretion GO:0051023 1 0.256
Mouse
cellular component movement GO:0006928 248 0.256
Mouse
response to oxidative stress GO:0006979 186 0.256
leukocyte chemotaxis GO:0030595 22 0.256
regulation of neuron death GO:1901214 115 0.254
cytokine mediated signaling pathway GO:0019221 43 0.253
Mouse
regulation of defense response GO:0031347 68 0.252
positive regulation of apoptotic process GO:0043065 154 0.237
cellular response to molecule of bacterial origin GO:0071219 56 0.234
Mouse
regulation of cellular protein metabolic process GO:0032268 267 0.231
Mouse Rat
regulation of cell differentiation GO:0045595 320 0.230
Mouse Rat
myeloid leukocyte migration GO:0097529 20 0.229
regulation of neurogenesis GO:0050767 247 0.221
Rat
secretion by cell GO:0032940 248 0.218
Mouse Rat
response to molecule of bacterial origin GO:0002237 194 0.216
regulation of fever generation GO:0031620 6 0.213
Mouse
cellular response to alkaloid GO:0071312 25 0.211
cellular response to nitrogen compound GO:1901699 210 0.208
Mouse
regulation of programmed cell death GO:0043067 341 0.198
vascular process in circulatory system GO:0003018 96 0.198
positive regulation of cell differentiation GO:0045597 217 0.197
Rat
cytokine production GO:0001816 61 0.197
positive regulation of phosphate metabolic process GO:0045937 262 0.194
Mouse
response to metal ion GO:0010038 253 0.194
positive regulation of response to stimulus GO:0048584 285 0.189
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.189
macromolecular complex assembly GO:0065003 273 0.188
cellular response to oxygen containing compound GO:1901701 386 0.187
Mouse
leukocyte migration GO:0050900 38 0.187
Mouse
single organism cellular localization GO:1902580 102 0.182
Mouse
regulation of protein metabolic process GO:0051246 289 0.180
Mouse Rat
response to purine containing compound GO:0014074 126 0.178
aging GO:0007568 241 0.178
response to growth factor GO:0070848 189 0.178
Rat
immune response GO:0006955 104 0.177
Zebrafish Mouse
regulation of blood vessel size GO:0050880 89 0.176
response to nicotine GO:0035094 51 0.173
secretion GO:0046903 307 0.172
Mouse Rat
positive regulation of immune system process GO:0002684 90 0.171
Mouse Rat
circulatory system development GO:0072359 134 0.171
regulation of rna biosynthetic process GO:2001141 381 0.171
Mouse
response to vitamin GO:0033273 131 0.171
negative regulation of cell differentiation GO:0045596 99 0.169
Mouse
response to vitamin d GO:0033280 34 0.167
cell cell signaling GO:0007267 335 0.166
regulation of nervous system development GO:0051960 264 0.166
Rat
regulation of protein transport GO:0051223 68 0.165
response to amino acid GO:0043200 75 0.164
Mouse
regulation of apoptotic process GO:0042981 335 0.163
positive regulation of neurogenesis GO:0050769 165 0.163
Rat
cellular response to acid chemical GO:0071229 75 0.160
Mouse
response to bacterium GO:0009617 200 0.160
neutrophil migration GO:1990266 12 0.158
response to reactive oxygen species GO:0000302 120 0.153
regulation of secretion GO:0051046 224 0.151
Mouse Rat
response to inorganic substance GO:0010035 377 0.150
programmed cell death GO:0012501 392 0.150
cell projection organization GO:0030030 302 0.150
cellular chemical homeostasis GO:0055082 247 0.147
Rat
positive regulation of protein transport GO:0051222 41 0.146
negative regulation of response to tumor cell GO:0002835 2 0.145
response to wounding GO:0009611 254 0.144
regulation of rna metabolic process GO:0051252 391 0.144
Mouse
regulation of leukocyte migration GO:0002685 24 0.143
blood circulation GO:0008015 183 0.142
positive regulation of developmental process GO:0051094 283 0.142
Mouse Rat
regulation of cytokine production GO:0001817 56 0.141
negative regulation of multicellular organismal process GO:0051241 203 0.141
Mouse
response to ionizing radiation GO:0010212 59 0.140
neutrophil chemotaxis GO:0030593 11 0.138
response to ketone GO:1901654 182 0.138
metal ion transport GO:0030001 289 0.137
protein complex biogenesis GO:0070271 263 0.137
response to ethanol GO:0045471 162 0.134
innate immune response GO:0045087 35 0.134
response to peptide GO:1901652 292 0.133
Rat
response to virus GO:0009615 17 0.132
Zebrafish
cell type specific apoptotic process GO:0097285 134 0.131
regulation of transferase activity GO:0051338 123 0.130
macromolecular complex subunit organization GO:0043933 339 0.129
regulation of establishment of protein localization GO:0070201 69 0.129
amine metabolic process GO:0009308 38 0.127
taxis GO:0042330 67 0.127
neuron differentiation GO:0030182 368 0.125
regulation of neuron differentiation GO:0045664 208 0.124
positive regulation of cell development GO:0010720 176 0.124
Rat
leukocyte cell cell adhesion GO:0007159 4 0.124
regulation of cell development GO:0060284 263 0.123
Mouse Rat
regulation of tube size GO:0035150 89 0.120
response to gamma radiation GO:0010332 24 0.117
regulation of inflammatory response GO:0050727 48 0.116
regulation of multicellular organismal development GO:2000026 376 0.116
Mouse Rat
response to nutrient levels GO:0031667 370 0.114
Rat
cellular calcium ion homeostasis GO:0006874 160 0.114
positive regulation of behavior GO:0048520 38 0.114
transcription dna templated GO:0006351 377 0.113
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.112
positive regulation of phosphorylation GO:0042327 177 0.112
Mouse
protein complex assembly GO:0006461 263 0.111
negative regulation of developmental process GO:0051093 125 0.111
Mouse
regeneration GO:0031099 163 0.109
cardiovascular system development GO:0072358 134 0.109
regulation of metal ion transport GO:0010959 118 0.104
negative regulation of rna biosynthetic process GO:1902679 118 0.103
Mouse
regulation of cell proliferation GO:0042127 359 0.103
g protein coupled purinergic receptor signaling pathway GO:0035588 8 0.101
response to acid chemical GO:0001101 222 0.101
Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.100
regulation of response to stress GO:0080134 126 0.100
response to estrogen GO:0043627 232 0.099
wound healing GO:0042060 122 0.098
gliogenesis GO:0042063 93 0.096
Rat
response to estradiol GO:0032355 164 0.095
positive regulation of nervous system development GO:0051962 178 0.095
Rat
regulation of molecular function GO:0065009 398 0.094
Mouse Rat
regulation of protein localization GO:0032880 81 0.093
regulation of anatomical structure size GO:0090066 135 0.092
response to hydrogen peroxide GO:0042542 89 0.091
positive regulation of response to external stimulus GO:0032103 51 0.090
cellular response to endogenous stimulus GO:0071495 377 0.090
Mouse
cell migration GO:0016477 197 0.088
Mouse
response to corticosteroid GO:0031960 235 0.087
positive regulation of leukocyte migration GO:0002687 21 0.087
neuron development GO:0048666 286 0.086
protein phosphorylation GO:0006468 345 0.086
Mouse
signal transduction by phosphorylation GO:0023014 144 0.086
Mouse
positive regulation of fever generation GO:0031622 5 0.085
Mouse
immunoglobulin mediated immune response GO:0016064 4 0.083
Mouse
negative regulation of programmed cell death GO:0043069 183 0.083
negative regulation of neuron death GO:1901215 69 0.081
regulation of phagocytosis engulfment GO:0060099 4 0.081
cellular homeostasis GO:0019725 252 0.081
Rat
learning or memory GO:0007611 90 0.079
protein complex subunit organization GO:0071822 302 0.079
regulation of secretion by cell GO:1903530 208 0.079
Mouse Rat
response to hypoxia GO:0001666 231 0.078
cellular ion homeostasis GO:0006873 184 0.078
Rat
neuron projection development GO:0031175 273 0.078
cellular response to lipopolysaccharide GO:0071222 55 0.078
Mouse
homeostatic process GO:0042592 331 0.078
Mouse Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.077
Mouse
response to dexamethasone GO:0071548 49 0.077
locomotion GO:0040011 237 0.076
Mouse
proteolysis GO:0006508 175 0.076
Mouse Rat
cellular component biogenesis GO:0044085 368 0.076
chemotaxis GO:0006935 66 0.076
protein oligomerization GO:0051259 191 0.075
hindlimb morphogenesis GO:0035137 2 0.075
response to carbohydrate GO:0009743 183 0.075
regulation of signal transduction GO:0009966 318 0.073
response to tumor cell GO:0002347 4 0.072
regulation of phosphorylation GO:0042325 248 0.072
Mouse
negative regulation of gene expression GO:0010629 199 0.072
Mouse
interleukin 1 biosynthetic process GO:0042222 1 0.071
multi multicellular organism process GO:0044706 138 0.071
cellular response to alcohol GO:0097306 87 0.071
negative regulation of signaling GO:0023057 157 0.071
negative regulation of cellular metabolic process GO:0031324 281 0.070
Mouse
cellular response to biotic stimulus GO:0071216 59 0.068
Mouse
negative regulation of immune response to tumor cell GO:0002838 2 0.068
negative regulation of cell death GO:0060548 229 0.068
regulation of leukocyte chemotaxis GO:0002688 12 0.068
cellular response to organonitrogen compound GO:0071417 197 0.068
Mouse
positive regulation of protein kinase b signaling GO:0051897 10 0.067
Mouse
response to glucocorticoid GO:0051384 223 0.067
limb morphogenesis GO:0035108 4 0.066
positive regulation of molecular function GO:0044093 230 0.065
Mouse Rat
regulation of protein kinase activity GO:0045859 105 0.065
response to increased oxygen levels GO:0036296 45 0.064
positive regulation of protein metabolic process GO:0051247 178 0.064
Mouse Rat
positive regulation of cytokine production GO:0001819 42 0.063
cytosolic calcium ion homeostasis GO:0051480 140 0.063
response to oxygen levels GO:0070482 265 0.063
cytokine secretion GO:0050663 15 0.062
Rat
cellular response to ketone GO:1901655 51 0.062
positive regulation of signal transduction GO:0009967 175 0.061
sensory perception of pain GO:0019233 73 0.061
cell chemotaxis GO:0060326 31 0.061
response to indole 3 methanol GO:0071680 2 0.061
regulation of nucleic acid templated transcription GO:1903506 380 0.060
Mouse
positive regulation of neuron differentiation GO:0045666 126 0.059
positive regulation of defense response GO:0031349 37 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.058
Mouse
response to peptide hormone GO:0043434 278 0.058
Rat
divalent inorganic cation transport GO:0072511 134 0.058
response to insulin GO:0032868 133 0.058
Rat
temperature homeostasis GO:0001659 17 0.058
Mouse
multi organism reproductive process GO:0044703 262 0.058
positive regulation of cellular amine metabolic process GO:0033240 3 0.058
blood vessel development GO:0001568 69 0.057
lymphocyte activation GO:0046649 43 0.057
regulation of lymphocyte chemotaxis GO:1901623 1 0.056
vesicle mediated transport GO:0016192 181 0.056
immune effector process GO:0002252 53 0.056
Mouse
regulation of ion transport GO:0043269 245 0.055
cellular cation homeostasis GO:0030003 180 0.055
Rat
mapk cascade GO:0000165 140 0.054
Mouse
response to glucose GO:0009749 136 0.054
cellular response to iron iii ion GO:0071283 3 0.054
anatomical structure formation involved in morphogenesis GO:0048646 83 0.054
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.053
cellular amine metabolic process GO:0044106 38 0.053
reproductive system development GO:0061458 128 0.053
Rat
regulation of response to external stimulus GO:0032101 106 0.053
positive regulation of protein kinase activity GO:0045860 73 0.053
positive regulation of kinase activity GO:0033674 77 0.052
intracellular transport GO:0046907 185 0.052
Mouse
granulocyte chemotaxis GO:0071621 15 0.052
chemical homeostasis GO:0048878 292 0.052
Rat
cellular response to interleukin 1 GO:0071347 37 0.051
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.050
Mouse
organelle organization GO:0006996 266 0.049
pseudopodium organization GO:0031268 3 0.049
regulation of immune response to tumor cell GO:0002837 3 0.048
calcium ion homeostasis GO:0055074 162 0.048
signal release GO:0023061 145 0.048
cellular response to stress GO:0033554 269 0.048
Mouse
regulation of kinase activity GO:0043549 117 0.048
reactive oxygen species biosynthetic process GO:1903409 8 0.047
cellular divalent inorganic cation homeostasis GO:0072503 162 0.047
positive regulation of catalytic activity GO:0043085 184 0.047
Mouse Rat
organophosphate metabolic process GO:0019637 370 0.047
hormone transport GO:0009914 121 0.046
axon development GO:0061564 96 0.046
regulation of catalytic activity GO:0050790 304 0.046
Mouse Rat
regulation of response to wounding GO:1903034 69 0.045
neurological system process GO:0050877 219 0.045
vitamin biosynthetic process GO:0009110 3 0.045
positive regulation of interleukin 1 alpha biosynthetic process GO:0050726 1 0.045
formation of primary germ layer GO:0001704 1 0.045
cognition GO:0050890 92 0.045
interleukin 1 alpha production GO:0032610 1 0.045
regulation of angiogenesis GO:0045765 39 0.044
localization of cell GO:0051674 202 0.044
Mouse
blood vessel morphogenesis GO:0048514 58 0.044
steroid biosynthetic process GO:0006694 48 0.044
rna metabolic process GO:0016070 406 0.043
Mouse
organ regeneration GO:0031100 101 0.043
peptide transport GO:0015833 97 0.043
Mouse
regulation of locomotion GO:0040012 148 0.043
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.043
positive regulation of cellular catabolic process GO:0031331 71 0.042
positive regulation of cytokine biosynthetic process GO:0042108 1 0.042
t helper 1 cell extravasation GO:0035687 1 0.042
jak stat cascade GO:0007259 26 0.042
cellular response to growth factor stimulus GO:0071363 162 0.042
regulation of behavior GO:0050795 61 0.042
regulation of immunoglobulin mediated immune response GO:0002889 2 0.042
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.041
cellular response to vitamin k GO:0071307 1 0.041
positive regulation of jak stat cascade GO:0046427 19 0.041
regulation of cellular amino acid metabolic process GO:0006521 2 0.041
glial cell differentiation GO:0010001 65 0.041
positive regulation of i kappab kinase nf kappab signaling GO:0043123 8 0.041
nitrogen compound transport GO:0071705 229 0.041
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.041
negative regulation of cellular biosynthetic process GO:0031327 161 0.041
Mouse
central nervous system development GO:0007417 311 0.040
regulation of membrane potential GO:0042391 110 0.040
embryonic hindlimb morphogenesis GO:0035116 2 0.040
reproduction GO:0000003 245 0.040
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.040
Mouse
negative regulation of biosynthetic process GO:0009890 168 0.040
Mouse
multicellular organismal reproductive process GO:0048609 233 0.040
regulation of osteoclast differentiation GO:0045670 8 0.040
Mouse Rat
single organism reproductive process GO:0044702 297 0.039
Rat
regulation of cell projection organization GO:0031344 175 0.039
regulation of homeostatic process GO:0032844 101 0.039
Mouse Rat
regulation of cellular component organization GO:0051128 368 0.039
ras protein signal transduction GO:0007265 29 0.039
purine containing compound metabolic process GO:0072521 253 0.039
negative regulation of apoptotic process GO:0043066 181 0.039
cellular response to interferon gamma GO:0071346 14 0.039
positive regulation of mapk cascade GO:0043410 92 0.039
Mouse
vitamin d metabolic process GO:0042359 4 0.039
positive regulation of neuron death GO:1901216 43 0.039
cellular metal ion homeostasis GO:0006875 172 0.039
metal ion homeostasis GO:0055065 186 0.038
cytokine biosynthetic process GO:0042089 3 0.038
response to cold GO:0009409 29 0.038
myeloid cell differentiation GO:0030099 22 0.038
Mouse Rat
positive regulation of locomotion GO:0040017 102 0.038
regulation of blood circulation GO:1903522 110 0.038
defense response to other organism GO:0098542 17 0.038
Zebrafish Mouse
endocytosis GO:0006897 84 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.037
Mouse
small gtpase mediated signal transduction GO:0007264 36 0.037
cellular response to peptide GO:1901653 133 0.037
positive regulation of biosynthetic process GO:0009891 319 0.037
Mouse
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
sexual reproduction GO:0019953 148 0.037
regulation of system process GO:0044057 208 0.037
embryonic appendage morphogenesis GO:0035113 4 0.036
single organism intracellular transport GO:1902582 166 0.036
Mouse
negative regulation of response to stimulus GO:0048585 155 0.036
peptidyl amino acid modification GO:0018193 126 0.036
protein targeting GO:0006605 61 0.036
Mouse
gastrulation GO:0007369 2 0.036
regulation of leukocyte differentiation GO:1902105 20 0.036
Mouse Rat
negative regulation of transcription dna templated GO:0045892 116 0.036
Mouse
single organism nuclear import GO:1902593 35 0.036
Mouse
response to interferon gamma GO:0034341 20 0.036
regulation of cytokine biosynthetic process GO:0042035 3 0.035
positive regulation of cellular protein metabolic process GO:0032270 167 0.035
Mouse Rat
cellular response to nutrient levels GO:0031669 60 0.035
lymphocyte activation involved in immune response GO:0002285 3 0.035
regulation of catabolic process GO:0009894 113 0.035
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.035
positive regulation of interleukin 1 alpha production GO:0032730 1 0.034
neuron neuron synaptic transmission GO:0007270 60 0.034
heterotypic cell cell adhesion GO:0034113 2 0.033
interleukin 12 production GO:0032615 3 0.033
regulation of cellular catabolic process GO:0031329 101 0.033
organonitrogen compound biosynthetic process GO:1901566 167 0.032
organic hydroxy compound metabolic process GO:1901615 115 0.032
heart contraction GO:0060047 57 0.032
cellular response to cytokine stimulus GO:0071345 127 0.032
Mouse
regulation of neuron projection development GO:0010975 161 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
positive regulation of ion transport GO:0043270 94 0.032
positive regulation of cellular component movement GO:0051272 102 0.032
response to toxic substance GO:0009636 133 0.032
locomotory behavior GO:0007626 15 0.031
negative regulation of ion transport GO:0043271 51 0.031
regulation of potassium ion transport GO:0043266 29 0.031
response to decreased oxygen levels GO:0036293 237 0.031
peptide metabolic process GO:0006518 32 0.031
negative regulation of cell proliferation GO:0008285 119 0.031
regulation of cell killing GO:0031341 12 0.031
nucleic acid templated transcription GO:0097659 379 0.030
Mouse
organic acid transport GO:0015849 116 0.030
negative regulation of amino acid transport GO:0051956 13 0.030
leukocyte activation GO:0045321 76 0.030
reproductive structure development GO:0048608 128 0.030
Rat
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.030
negative regulation of metabolic process GO:0009892 331 0.030
Mouse
cellular response to extracellular stimulus GO:0031668 73 0.030
cellular response to lipoprotein particle stimulus GO:0071402 5 0.030
rhythmic process GO:0048511 156 0.030
multicellular organismal signaling GO:0035637 44 0.030
regulation of cellular localization GO:0060341 263 0.030
Mouse Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.029
Rat
protein secretion GO:0009306 34 0.029
Mouse Rat
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.029
calcium ion transport GO:0006816 131 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
regulation of hydrolase activity GO:0051336 143 0.029
Mouse Rat
actin cytoskeleton organization GO:0030036 73 0.029
regulation of cell motility GO:2000145 131 0.029
cytoskeleton organization GO:0007010 111 0.029
regulation of i kappab kinase nf kappab signaling GO:0043122 13 0.029
ion homeostasis GO:0050801 212 0.029
Rat
organic anion transport GO:0015711 132 0.028
regulation of transcription dna templated GO:0006355 374 0.028
Mouse
positive regulation of chemotaxis GO:0050921 23 0.028
negative regulation of innate immune response GO:0045824 4 0.028
embryonic limb morphogenesis GO:0030326 4 0.028
positive regulation of protein modification process GO:0031401 142 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
Mouse
regulation of synaptic plasticity GO:0048167 70 0.028
positive regulation of nucleotide metabolic process GO:0045981 91 0.028
cation homeostasis GO:0055080 195 0.028
Rat
response to high density lipoprotein particle GO:0055099 2 0.028
negative regulation of immune system process GO:0002683 39 0.028
sex differentiation GO:0007548 113 0.028
Rat
response to electrical stimulus GO:0051602 56 0.027
dna metabolic process GO:0006259 96 0.027
positive regulation of map kinase activity GO:0043406 46 0.027
response to mechanical stimulus GO:0009612 134 0.027
appendage morphogenesis GO:0035107 4 0.027
lipid metabolic process GO:0006629 283 0.027
response to heat GO:0009408 60 0.027
development of primary sexual characteristics GO:0045137 107 0.027
Rat
regulation of protein modification process GO:0031399 194 0.027
Mouse
organonitrogen compound catabolic process GO:1901565 179 0.027
myeloid leukocyte differentiation GO:0002573 20 0.027
Mouse Rat
response to low density lipoprotein particle GO:0055098 4 0.027
memory GO:0007613 54 0.027
regulation of neutrophil migration GO:1902622 6 0.026
purinergic receptor signaling pathway GO:0035587 10 0.026
reproductive process GO:0022414 372 0.026
Rat
cellular response to lipoteichoic acid GO:0071223 1 0.026
vasculature development GO:0001944 70 0.026
response to activity GO:0014823 73 0.026
response to retinoic acid GO:0032526 63 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
synaptic transmission GO:0007268 235 0.026
divalent metal ion transport GO:0070838 132 0.026
positive regulation of neuron projection development GO:0010976 99 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
Mouse
negative regulation of neuron differentiation GO:0045665 62 0.025
g protein coupled receptor signaling pathway GO:0007186 242 0.025
reactive nitrogen species metabolic process GO:2001057 1 0.025
regulation of cellular component movement GO:0051270 150 0.025
response to organophosphorus GO:0046683 102 0.025
immune response to tumor cell GO:0002418 3 0.025
pseudopodium assembly GO:0031269 3 0.025
regulation of peptide secretion GO:0002791 82 0.025
adenosine receptor signaling pathway GO:0001973 7 0.025
regulation of peptide transport GO:0090087 87 0.025
Mouse
peptide hormone secretion GO:0030072 84 0.025
regulation of acute inflammatory response GO:0002673 23 0.025
Mouse
anion transport GO:0006820 178 0.025
response to transition metal nanoparticle GO:1990267 122 0.025
negative regulation of collagen biosynthetic process GO:0032966 4 0.025
hemopoiesis GO:0030097 34 0.025
Mouse Rat
positive regulation of catabolic process GO:0009896 78 0.025
transmembrane transport GO:0055085 412 0.025
regulation of endothelial cell apoptotic process GO:2000351 3 0.025
cellular protein localization GO:0034613 122 0.025
Mouse
cellular component assembly GO:0022607 360 0.024
positive regulation of isotype switching GO:0045830 1 0.024
regulation of heterotypic cell cell adhesion GO:0034114 2 0.024
response to hyperoxia GO:0055093 45 0.024
protein kinase b signaling GO:0043491 18 0.024
Mouse
rna biosynthetic process GO:0032774 380 0.024
Mouse
tissue morphogenesis GO:0048729 22 0.024
Mouse
regulation of synaptic transmission GO:0050804 141 0.024
positive regulation of cell migration GO:0030335 96 0.024
regulation of map kinase activity GO:0043405 53 0.024
olfactory learning GO:0008355 1 0.023
fat soluble vitamin biosynthetic process GO:0042362 2 0.023
eosinophil chemotaxis GO:0048245 3 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.023
digestive system development GO:0055123 41 0.023
immunoglobulin secretion GO:0048305 1 0.023
Mouse
ribonucleotide metabolic process GO:0009259 231 0.023
sodium ion transport GO:0006814 82 0.023
cell activation GO:0001775 97 0.023
amide transport GO:0042886 105 0.023
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.023
Mouse
erbb signaling pathway GO:0038127 23 0.023
Rat
interleukin 1 alpha biosynthetic process GO:0050719 1 0.022
hormone secretion GO:0046879 115 0.022
cellular response to nutrient GO:0031670 30 0.022
negative regulation of nervous system development GO:0051961 79 0.022
response to alkyl hydroperoxide GO:0033195 1 0.022
peptidyl tyrosine phosphorylation GO:0018108 72 0.022
lymphocyte chemotaxis GO:0048247 3 0.022
maintenance of location GO:0051235 17 0.022
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
Rat
cellular amino acid metabolic process GO:0006520 107 0.022
regulation of erk1 and erk2 cascade GO:0070372 41 0.022
regulation of response to tumor cell GO:0002834 3 0.021
circadian rhythm GO:0007623 88 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
Mouse
interleukin 1 production GO:0032612 11 0.021
positive regulation of angiogenesis GO:0045766 28 0.021
striated muscle contraction GO:0006941 44 0.021
regulation of interleukin 12 production GO:0032655 3 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
Rat

Tnf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.027
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
disease of cellular proliferation DOID:14566 0 0.025