Rattus norvegicus

0 known processes

Toe1

target of EGR1, member 1 (nuclear)

Toe1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.357
positive regulation of retinal cell programmed cell death GO:0046670 1 0.192
cellular response to hormone stimulus GO:0032870 247 0.172
macromolecular complex subunit organization GO:0043933 339 0.157
cellular component assembly GO:0022607 360 0.142
cellular component biogenesis GO:0044085 368 0.127
transcription dna templated GO:0006351 377 0.115
positive regulation of response to stimulus GO:0048584 285 0.112
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.101
positive regulation of gene expression GO:0010628 244 0.099
cellular response to stress GO:0033554 269 0.096
cellular response to organic cyclic compound GO:0071407 202 0.095
regulation of rna biosynthetic process GO:2001141 381 0.095
positive regulation of cellular biosynthetic process GO:0031328 295 0.088
protein oligomerization GO:0051259 191 0.084
protein complex subunit organization GO:0071822 302 0.072
regulation of cell proliferation GO:0042127 359 0.067
regulation of transcription dna templated GO:0006355 374 0.065
rna metabolic process GO:0016070 406 0.063
response to inorganic substance GO:0010035 377 0.063
regulation of retinal cell programmed cell death GO:0046668 1 0.061
nucleic acid templated transcription GO:0097659 379 0.060
multi organism reproductive process GO:0044703 262 0.059
regulation of programmed cell death GO:0043067 341 0.058
neuron death GO:0070997 127 0.058
negative regulation of metabolic process GO:0009892 331 0.058
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.056
reproductive process GO:0022414 372 0.056
cellular response to oxygen containing compound GO:1901701 386 0.056
positive regulation of nucleic acid templated transcription GO:1903508 197 0.055
organic acid metabolic process GO:0006082 292 0.054
neuron development GO:0048666 286 0.054
positive regulation of humoral immune response GO:0002922 2 0.054
regulation of interleukin 1 secretion GO:0050704 3 0.053
positive regulation of signal transduction GO:0009967 175 0.052
programmed cell death GO:0012501 392 0.052
negative regulation of cell death GO:0060548 229 0.052
response to metal ion GO:0010038 253 0.052
macromolecular complex assembly GO:0065003 273 0.051
positive regulation of biosynthetic process GO:0009891 319 0.049
positive regulation of protein metabolic process GO:0051247 178 0.049
regulation of interleukin 1 beta secretion GO:0050706 3 0.048
cellular response to organonitrogen compound GO:0071417 197 0.047
response to monosaccharide GO:0034284 159 0.046
negative regulation of cellular metabolic process GO:0031324 281 0.045
protein complex assembly GO:0006461 263 0.044
response to decreased oxygen levels GO:0036293 237 0.044
cellular catabolic process GO:0044248 295 0.044
positive regulation of catalytic activity GO:0043085 184 0.043
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
positive regulation of interleukin 1 secretion GO:0050716 3 0.041
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.041
response to cytokine GO:0034097 215 0.041
regulation of cell migration GO:0030334 128 0.039
protein complex biogenesis GO:0070271 263 0.039
single organism intracellular transport GO:1902582 166 0.039
positive regulation of phosphorylation GO:0042327 177 0.038
negative regulation of response to stimulus GO:0048585 155 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.038
response to peptide GO:1901652 292 0.037
positive regulation of cell communication GO:0010647 271 0.037
rna biosynthetic process GO:0032774 380 0.036
vesicle mediated transport GO:0016192 181 0.035
biological adhesion GO:0022610 110 0.035
response to extracellular stimulus GO:0009991 380 0.034
positive regulation of cellular component organization GO:0051130 200 0.033
cellular component movement GO:0006928 248 0.033
apoptotic process GO:0006915 381 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
organonitrogen compound biosynthetic process GO:1901566 167 0.032
response to external biotic stimulus GO:0043207 221 0.032
response to oxidative stress GO:0006979 186 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
protein localization GO:0008104 191 0.031
response to radiation GO:0009314 137 0.031
protein transport GO:0015031 132 0.031
intracellular signal transduction GO:0035556 314 0.030
regulation of signal transduction GO:0009966 318 0.029
cellular response to external stimulus GO:0071496 118 0.029
response to hypoxia GO:0001666 231 0.029
negative regulation of actin filament polymerization GO:0030837 4 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
glycosyl compound catabolic process GO:1901658 126 0.028
positive regulation of cell development GO:0010720 176 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.027
circadian sleep wake cycle sleep GO:0050802 21 0.027
circadian sleep wake cycle GO:0042745 23 0.027
cellular macromolecule localization GO:0070727 122 0.027
proteolysis GO:0006508 175 0.027
multicellular organism reproduction GO:0032504 233 0.027
response to glucose GO:0009749 136 0.027
catabolic process GO:0009056 351 0.026
regulation of protein transport GO:0051223 68 0.026
cellular response to reactive oxygen species GO:0034614 55 0.026
cell activation GO:0001775 97 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
response to ionizing radiation GO:0010212 59 0.026
regulation of catalytic activity GO:0050790 304 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
response to peptide hormone GO:0043434 278 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
regulation of neuron death GO:1901214 115 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.025
regulation of establishment of protein localization GO:0070201 69 0.025
response to hydrogen peroxide GO:0042542 89 0.024
regulation of circadian sleep wake cycle GO:0042749 18 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
cell motility GO:0048870 202 0.024
macromolecule localization GO:0033036 252 0.024
positive regulation of developmental process GO:0051094 283 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.024
cell growth GO:0016049 104 0.024
regulation of apoptotic process GO:0042981 335 0.023
single organism catabolic process GO:0044712 283 0.023
cellular protein localization GO:0034613 122 0.023
regulation of circadian sleep wake cycle sleep GO:0045187 18 0.023
sensory organ development GO:0007423 74 0.023
reproductive structure development GO:0048608 128 0.023
regulation of lymphocyte migration GO:2000401 1 0.022
regulation of rna metabolic process GO:0051252 391 0.022
positive regulation of signaling GO:0023056 270 0.022
regulation of neuron apoptotic process GO:0043523 83 0.022
localization of cell GO:0051674 202 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
single organism reproductive process GO:0044702 297 0.022
response to wounding GO:0009611 254 0.022
leukocyte activation GO:0045321 76 0.022
positive regulation of transport GO:0051050 245 0.022
protein homooligomerization GO:0051260 91 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
cellular ketone metabolic process GO:0042180 51 0.021
sexual reproduction GO:0019953 148 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
regulation of molecular function GO:0065009 398 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
purine containing compound catabolic process GO:0072523 138 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
regulation of protein metabolic process GO:0051246 289 0.020
embryonic pattern specification GO:0009880 1 0.020
regulation of cell differentiation GO:0045595 320 0.020
response to reactive oxygen species GO:0000302 120 0.020
single organism biosynthetic process GO:0044711 342 0.020
response to growth factor GO:0070848 189 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
aging GO:0007568 241 0.020
tissue development GO:0009888 252 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
wound healing GO:0042060 122 0.019
reproduction GO:0000003 245 0.019
protein heterooligomerization GO:0051291 89 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.019
brain development GO:0007420 247 0.019
dna metabolic process GO:0006259 96 0.019
cellular response to abiotic stimulus GO:0071214 85 0.019
cellular response to oxidative stress GO:0034599 76 0.019
negative regulation of gene expression GO:0010629 199 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
reproductive system development GO:0061458 128 0.019
single organism cellular localization GO:1902580 102 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.019
response to nutrient levels GO:0031667 370 0.019
neurological system process GO:0050877 219 0.018
regulation of cytokine production GO:0001817 56 0.018
cellular chemical homeostasis GO:0055082 247 0.018
peptide biosynthetic process GO:0043043 3 0.018
response to carbohydrate GO:0009743 183 0.018
embryonic axis specification GO:0000578 1 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
regulation of lipid metabolic process GO:0019216 68 0.018
central nervous system development GO:0007417 311 0.018
organic substance catabolic process GO:1901575 316 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
spindle organization GO:0007051 2 0.018
response to gamma radiation GO:0010332 24 0.018
regulation of cell motility GO:2000145 131 0.018
cellular response to peptide GO:1901653 133 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
oxoacid metabolic process GO:0043436 290 0.018
regulation of cellular component organization GO:0051128 368 0.018
cell type specific apoptotic process GO:0097285 134 0.017
interleukin 1 secretion GO:0050701 3 0.017
mitotic spindle organization GO:0007052 2 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
response to other organism GO:0051707 220 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
neuron apoptotic process GO:0051402 88 0.017
cellular response to extracellular stimulus GO:0031668 73 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
intracellular protein transport GO:0006886 79 0.017
acute inflammatory response to non antigenic stimulus GO:0002525 2 0.017
protein phosphorylation GO:0006468 345 0.017
response to hexose GO:0009746 144 0.017
sleep GO:0030431 30 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
neuron differentiation GO:0030182 368 0.016
regulation of cell development GO:0060284 263 0.016
positive regulation of behavior GO:0048520 38 0.016
regulation of cell cycle arrest GO:0071156 2 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
organelle organization GO:0006996 266 0.016
amine metabolic process GO:0009308 38 0.016
cell projection organization GO:0030030 302 0.016
regulation of growth GO:0040008 105 0.016
regulation of immune system process GO:0002682 123 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
rhythmic behavior GO:0007622 24 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
nucleoside metabolic process GO:0009116 179 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
lens development in camera type eye GO:0002088 13 0.015
axis specification GO:0009798 4 0.015
gliogenesis GO:0042063 93 0.015
cell adhesion GO:0007155 110 0.015
tube development GO:0035295 89 0.015
b cell differentiation GO:0030183 2 0.015
cell migration GO:0016477 197 0.015
circulatory system process GO:0003013 183 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.014
regulation of nervous system development GO:0051960 264 0.014
cell cycle checkpoint GO:0000075 2 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
heart morphogenesis GO:0003007 3 0.014
positive regulation of protein modification process GO:0031401 142 0.014
cellular response to alcohol GO:0097306 87 0.014
chromosome organization GO:0051276 36 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
cellular response to lipid GO:0071396 201 0.014
regulation of anatomical structure size GO:0090066 135 0.014
response to mechanical stimulus GO:0009612 134 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
dna replication GO:0006260 37 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
cellular amine metabolic process GO:0044106 38 0.013
intracellular transport GO:0046907 185 0.013
response to ketone GO:1901654 182 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
protein maturation GO:0051604 68 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
response to estradiol GO:0032355 164 0.013
rhythmic process GO:0048511 156 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
response to estrogen GO:0043627 232 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
establishment of protein localization GO:0045184 141 0.013
cardiovascular system development GO:0072358 134 0.013
regulation of hydrolase activity GO:0051336 143 0.013
regulation of response to stress GO:0080134 126 0.013
developmental process involved in reproduction GO:0003006 159 0.012
cytokinetic process GO:0032506 1 0.012
female gonad development GO:0008585 53 0.012
response to temperature stimulus GO:0009266 94 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
epithelium development GO:0060429 96 0.012
defense response GO:0006952 194 0.012
response to anoxia GO:0034059 4 0.012
cytokine production GO:0001816 61 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
interleukin 1 beta secretion GO:0050702 3 0.012
response to x ray GO:0010165 15 0.012
response to glucocorticoid GO:0051384 223 0.012
chemical homeostasis GO:0048878 292 0.012
circadian rhythm GO:0007623 88 0.012
multicellular organism growth GO:0035264 1 0.012
ras protein signal transduction GO:0007265 29 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
gamete generation GO:0007276 124 0.012
immune response GO:0006955 104 0.012
homeostatic process GO:0042592 331 0.012
regulation of mesenchymal cell proliferation GO:0010464 4 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.012
dna packaging GO:0006323 4 0.011
regulation of cell projection organization GO:0031344 175 0.011
regulation of cellular localization GO:0060341 263 0.011
macromolecule catabolic process GO:0009057 58 0.011
response to acid chemical GO:0001101 222 0.011
regulation of locomotion GO:0040012 148 0.011
regulation of protein modification process GO:0031399 194 0.011
neuron projection development GO:0031175 273 0.011
response to tumor necrosis factor GO:0034612 56 0.011
regulation of notch signaling pathway GO:0008593 3 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
wnt signaling pathway GO:0016055 17 0.011
protein import GO:0017038 37 0.011
protein targeting GO:0006605 61 0.011
sex differentiation GO:0007548 113 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
regulation of peptidase activity GO:0052547 55 0.011
cell differentiation involved in kidney development GO:0061005 4 0.011
regulation of protein secretion GO:0050708 28 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
single organism organelle organization GO:1902589 180 0.011
epithelial cell differentiation GO:0030855 71 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
hemostasis GO:0007599 26 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
kidney development GO:0001822 67 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
cellular response to growth factor stimulus GO:0071363 162 0.010
dna integrity checkpoint GO:0031570 2 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
regulation of neurogenesis GO:0050767 247 0.010
regulation of secretion GO:0051046 224 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
cellular response to insulin stimulus GO:0032869 81 0.010
retinal cell programmed cell death GO:0046666 1 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
positive regulation of tolerance induction GO:0002645 1 0.010
spermatogenesis GO:0007283 99 0.010
muscle cell differentiation GO:0042692 52 0.010
growth GO:0040007 165 0.010
activation of cysteine type endopeptidase activity GO:0097202 4 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
response to biotic stimulus GO:0009607 226 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
cytoplasmic transport GO:0016482 115 0.010

Toe1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011