Rattus norvegicus

38 known processes

Tollip

toll interacting protein

Tollip biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 295 0.171
organelle organization GO:0006996 266 0.141
catabolic process GO:0009056 351 0.099
regulation of cellular component organization GO:0051128 368 0.085
negative regulation of metabolic process GO:0009892 331 0.078
organic substance catabolic process GO:1901575 316 0.078
rna biosynthetic process GO:0032774 380 0.068
protein modification by small protein conjugation GO:0032446 31 0.068
protein modification by small protein conjugation or removal GO:0070647 35 0.066
regulation of molecular function GO:0065009 398 0.061
synaptic transmission GO:0007268 235 0.059
single organism reproductive process GO:0044702 297 0.057
regulation of rna biosynthetic process GO:2001141 381 0.056
negative regulation of cellular metabolic process GO:0031324 281 0.054
reproductive process GO:0022414 372 0.053
cellular macromolecule catabolic process GO:0044265 29 0.048
regulation of synaptic transmission GO:0050804 141 0.046
carboxylic acid metabolic process GO:0019752 289 0.044
chromosome segregation GO:0007059 2 0.044
cell cell signaling GO:0007267 335 0.043
regulation of cell differentiation GO:0045595 320 0.042
positive regulation of multicellular organismal process GO:0051240 387 0.042
intracellular signal transduction GO:0035556 314 0.042
intracellular transport GO:0046907 185 0.042
cell cycle GO:0007049 101 0.041
negative regulation of biosynthetic process GO:0009890 168 0.040
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.040
single organism organelle organization GO:1902589 180 0.040
nucleic acid templated transcription GO:0097659 379 0.039
regulation of cell cycle g2 m phase transition GO:1902749 4 0.039
ubiquitin dependent protein catabolic process GO:0006511 14 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
establishment of protein localization GO:0045184 141 0.038
vesicle mediated transport GO:0016192 181 0.038
regulation of transcription dna templated GO:0006355 374 0.038
regulation of cell cycle phase transition GO:1901987 12 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
rna metabolic process GO:0016070 406 0.037
s adenosylhomocysteine catabolic process GO:0019510 1 0.036
regulation of rna metabolic process GO:0051252 391 0.036
growth GO:0040007 165 0.035
amine metabolic process GO:0009308 38 0.035
transcription dna templated GO:0006351 377 0.035
reproduction GO:0000003 245 0.035
positive regulation of developmental process GO:0051094 283 0.034
protein complex subunit organization GO:0071822 302 0.034
immune system process GO:0002376 204 0.034
cellular amino acid metabolic process GO:0006520 107 0.034
positive regulation of phosphorylation GO:0042327 177 0.032
sexual reproduction GO:0019953 148 0.032
purine nucleoside metabolic process GO:0042278 169 0.032
nucleobase containing compound catabolic process GO:0034655 152 0.032
ion homeostasis GO:0050801 212 0.032
macromolecule localization GO:0033036 252 0.031
macromolecular complex subunit organization GO:0043933 339 0.031
cell morphogenesis GO:0000902 142 0.031
regulation of cellular protein metabolic process GO:0032268 267 0.031
negative regulation of cell cycle phase transition GO:1901988 4 0.031
modification dependent protein catabolic process GO:0019941 14 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
multicellular organism reproduction GO:0032504 233 0.030
cell cycle checkpoint GO:0000075 2 0.029
cellular ketone metabolic process GO:0042180 51 0.029
protein ubiquitination GO:0016567 28 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
metal ion transport GO:0030001 289 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
ion transmembrane transport GO:0034220 365 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
regulation of cell development GO:0060284 263 0.028
multi organism reproductive process GO:0044703 262 0.028
cellular modified amino acid catabolic process GO:0042219 1 0.028
secretion GO:0046903 307 0.028
neuron projection development GO:0031175 273 0.028
regulation of stem cell differentiation GO:2000736 2 0.027
oxoacid metabolic process GO:0043436 290 0.027
regulation of protein metabolic process GO:0051246 289 0.027
single organism catabolic process GO:0044712 283 0.027
regulation of g2 m transition of mitotic cell cycle GO:0010389 4 0.027
multicellular organismal reproductive process GO:0048609 233 0.027
transmembrane transport GO:0055085 412 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
cell cycle process GO:0022402 57 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
anatomical structure morphogenesis GO:0009653 298 0.025
gamete generation GO:0007276 124 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
regulation of vesicle mediated transport GO:0060627 81 0.025
cellular amine metabolic process GO:0044106 38 0.025
negative regulation of nucleic acid templated transcription GO:1903507 117 0.025
embryonic pattern specification GO:0009880 1 0.024
single organism intracellular transport GO:1902582 166 0.024
cellular response to stress GO:0033554 269 0.024
regulation of anion transport GO:0044070 43 0.023
heterocycle catabolic process GO:0046700 167 0.023
axon cargo transport GO:0008088 1 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
regulation of phosphorylation GO:0042325 248 0.023
programmed cell death GO:0012501 392 0.023
regulation of signal transduction GO:0009966 318 0.023
organic acid metabolic process GO:0006082 292 0.022
endocytosis GO:0006897 84 0.022
multicellular organism growth GO:0035264 1 0.021
regulation of protein modification process GO:0031399 194 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
cellular component assembly GO:0022607 360 0.021
cation transport GO:0006812 382 0.021
cellular component biogenesis GO:0044085 368 0.021
protein catabolic process GO:0030163 30 0.021
regulation of system process GO:0044057 208 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
organophosphate metabolic process GO:0019637 370 0.020
neuromuscular synaptic transmission GO:0007274 2 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.020
regulation of cell proliferation GO:0042127 359 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
small molecule biosynthetic process GO:0044283 124 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
positive regulation of signaling GO:0023056 270 0.020
positive regulation of cell communication GO:0010647 271 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.019
proteolysis GO:0006508 175 0.019
endosomal transport GO:0016197 14 0.019
cellular protein catabolic process GO:0044257 19 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.019
regulation of membrane potential GO:0042391 110 0.019
secretion by cell GO:0032940 248 0.019
regulation of nervous system development GO:0051960 264 0.019
developmental growth GO:0048589 100 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
cellular chemical homeostasis GO:0055082 247 0.018
cell projection organization GO:0030030 302 0.018
regulation of secretion GO:0051046 224 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
synaptic vesicle endocytosis GO:0048488 4 0.018
homocysteine metabolic process GO:0050667 6 0.018
neuron differentiation GO:0030182 368 0.018
single organism biosynthetic process GO:0044711 342 0.018
anion transport GO:0006820 178 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
homeostatic process GO:0042592 331 0.017
axis specification GO:0009798 4 0.017
purine containing compound metabolic process GO:0072521 253 0.017
adult locomotory behavior GO:0008344 4 0.017
positive regulation of protein modification process GO:0031401 142 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
head development GO:0060322 247 0.017
chemical homeostasis GO:0048878 292 0.017
response to inorganic substance GO:0010035 377 0.017
lipid storage GO:0019915 1 0.017
sodium ion transport GO:0006814 82 0.017
protein complex assembly GO:0006461 263 0.017
cation transmembrane transport GO:0098655 263 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
nucleoside catabolic process GO:0009164 126 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
anterior posterior pattern specification GO:0009952 1 0.016
lipid metabolic process GO:0006629 283 0.016
ras protein signal transduction GO:0007265 29 0.016
regulation of catalytic activity GO:0050790 304 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
regulation of organelle organization GO:0033043 80 0.016
positive regulation of molecular function GO:0044093 230 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
sulfur amino acid metabolic process GO:0000096 9 0.015
steroid metabolic process GO:0008202 73 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
regulation of cell cycle GO:0051726 73 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
meiotic cell cycle process GO:1903046 3 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
circadian regulation of gene expression GO:0032922 3 0.015
macromolecule catabolic process GO:0009057 58 0.014
positive regulation of nervous system development GO:0051962 178 0.014
regulation of neurogenesis GO:0050767 247 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
response to nutrient levels GO:0031667 370 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
sister chromatid segregation GO:0000819 1 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 3 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
regulation of hormone levels GO:0010817 187 0.014
cellular cation homeostasis GO:0030003 180 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
cellular macromolecule localization GO:0070727 122 0.013
neuromuscular process GO:0050905 2 0.013
cellular homeostasis GO:0019725 252 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
regulation of neuron projection development GO:0010975 161 0.013
positive regulation of signal transduction GO:0009967 175 0.013
neuron development GO:0048666 286 0.013
gtp catabolic process GO:0006184 71 0.013
cellular modified amino acid metabolic process GO:0006575 61 0.013
membrane organization GO:0061024 94 0.013
cellular modified amino acid biosynthetic process GO:0042398 18 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
vesicle organization GO:0016050 29 0.013
regulation of transferase activity GO:0051338 123 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
positive regulation of cell development GO:0010720 176 0.013
defense response GO:0006952 194 0.013
nitrogen compound transport GO:0071705 229 0.013
lipid biosynthetic process GO:0008610 128 0.012
cellular component movement GO:0006928 248 0.012
alpha amino acid biosynthetic process GO:1901607 23 0.012
protein localization GO:0008104 191 0.012
alpha amino acid catabolic process GO:1901606 20 0.012
dna integrity checkpoint GO:0031570 2 0.012
negative regulation of gene expression GO:0010629 199 0.012
muscle system process GO:0003012 115 0.012
modification dependent macromolecule catabolic process GO:0043632 14 0.012
embryonic axis specification GO:0000578 1 0.012
signal release GO:0023061 145 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
aging GO:0007568 241 0.012
cellular component morphogenesis GO:0032989 155 0.012
neurotransmitter secretion GO:0007269 33 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
regulation of receptor activity GO:0010469 29 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
negative regulation of molecular function GO:0044092 133 0.012
glycosyl compound metabolic process GO:1901657 182 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
protein phosphorylation GO:0006468 345 0.011
calcium ion homeostasis GO:0055074 162 0.011
protein complex biogenesis GO:0070271 263 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
cytoplasmic transport GO:0016482 115 0.011
response to extracellular stimulus GO:0009991 380 0.011
regulation of protein kinase activity GO:0045859 105 0.011
respiratory system development GO:0060541 45 0.011
cation homeostasis GO:0055080 195 0.011
macromolecular complex assembly GO:0065003 273 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
sulfur compound catabolic process GO:0044273 3 0.011
developmental process involved in reproduction GO:0003006 159 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
cellular protein localization GO:0034613 122 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
potassium ion transport GO:0006813 97 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
organic anion transport GO:0015711 132 0.011
regulation of neuron differentiation GO:0045664 208 0.011
hormone transport GO:0009914 121 0.011
nucleoside metabolic process GO:0009116 179 0.011
negative regulation of developmental process GO:0051093 125 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
response to oxygen levels GO:0070482 265 0.011
regulation of cell cycle process GO:0010564 31 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
response to decreased oxygen levels GO:0036293 237 0.010
spindle organization GO:0007051 2 0.010
response to oxidative stress GO:0006979 186 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
regulation of neurotransmitter levels GO:0001505 42 0.010
mitotic cell cycle phase transition GO:0044772 20 0.010
apoptotic process GO:0006915 381 0.010
phosphatidylcholine biosynthetic process GO:0006656 5 0.010
aromatic compound catabolic process GO:0019439 168 0.010
nucleosome organization GO:0034728 1 0.010
cellular ion homeostasis GO:0006873 184 0.010

Tollip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.012