Rattus norvegicus

5 known processes

Tpi1

triosephosphate isomerase 1

(Aliases: MGC156639,Tpi)

Tpi1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate catabolic process GO:0016052 40 1.000
single organism carbohydrate catabolic process GO:0044724 40 0.999
generation of precursor metabolites and energy GO:0006091 62 0.981
monocarboxylic acid metabolic process GO:0032787 152 0.892
coenzyme metabolic process GO:0006732 86 0.888
carboxylic acid metabolic process GO:0019752 289 0.876
organic acid metabolic process GO:0006082 292 0.866
oxoacid metabolic process GO:0043436 290 0.835
glycolytic process GO:0006096 17 0.791
monosaccharide metabolic process GO:0005996 61 0.716
single organism catabolic process GO:0044712 283 0.712
pyridine containing compound metabolic process GO:0072524 32 0.669
single organism biosynthetic process GO:0044711 342 0.591
gluconeogenesis GO:0006094 15 0.583
carbohydrate metabolic process GO:0005975 130 0.535
nucleobase containing small molecule metabolic process GO:0055086 316 0.530
organic substance catabolic process GO:1901575 316 0.521
response to organophosphorus GO:0046683 102 0.516
single organism carbohydrate metabolic process GO:0044723 118 0.492
glucose metabolic process GO:0006006 52 0.482
organophosphate metabolic process GO:0019637 370 0.473
response to camp GO:0051591 91 0.462
purine ribonucleoside biosynthetic process GO:0046129 21 0.443
pyruvate metabolic process GO:0006090 27 0.390
catabolic process GO:0009056 351 0.384
hexose biosynthetic process GO:0019319 15 0.325
regulation of programmed cell death GO:0043067 341 0.296
purine nucleoside triphosphate metabolic process GO:0009144 141 0.294
hexose metabolic process GO:0019318 58 0.276
cellular response to peptide hormone stimulus GO:0071375 120 0.271
pyridine nucleotide metabolic process GO:0019362 28 0.241
carbohydrate biosynthetic process GO:0016051 42 0.241
purine ribonucleotide biosynthetic process GO:0009152 81 0.230
response to peptide hormone GO:0043434 278 0.206
regulation of neurogenesis GO:0050767 247 0.198
cofactor metabolic process GO:0051186 95 0.190
regulation of apoptotic process GO:0042981 335 0.180
response to nutrient GO:0007584 248 0.179
response to hypoxia GO:0001666 231 0.176
response to oxidative stress GO:0006979 186 0.175
lactate metabolic process GO:0006089 3 0.171
nucleoside triphosphate metabolic process GO:0009141 144 0.167
nucleoside phosphate metabolic process GO:0006753 283 0.163
organophosphate biosynthetic process GO:0090407 143 0.162
nucleotide metabolic process GO:0009117 279 0.161
purine nucleoside monophosphate metabolic process GO:0009126 84 0.147
positive regulation of programmed cell death GO:0043068 157 0.146
response to decreased oxygen levels GO:0036293 237 0.133
liver development GO:0001889 90 0.129
gland development GO:0048732 155 0.127
response to peptide GO:1901652 292 0.123
programmed cell death GO:0012501 392 0.120
response to purine containing compound GO:0014074 126 0.118
apoptotic process GO:0006915 381 0.113
proteolysis GO:0006508 175 0.112
response to extracellular stimulus GO:0009991 380 0.109
purine nucleotide biosynthetic process GO:0006164 83 0.106
protein complex biogenesis GO:0070271 263 0.103
cellular response to endogenous stimulus GO:0071495 377 0.103
cellular response to oxygen containing compound GO:1901701 386 0.101
ribonucleoside biosynthetic process GO:0042455 25 0.101
nad metabolic process GO:0019674 15 0.100
cellular component assembly GO:0022607 360 0.099
response to hexose GO:0009746 144 0.095
response to temperature stimulus GO:0009266 94 0.095
response to inorganic substance GO:0010035 377 0.091
ribonucleoside triphosphate metabolic process GO:0009199 141 0.089
response to estrogen GO:0043627 232 0.088
carboxylic acid biosynthetic process GO:0046394 83 0.086
alpha amino acid metabolic process GO:1901605 71 0.085
negative regulation of metabolic process GO:0009892 331 0.083
response to other organism GO:0051707 220 0.079
regulation of neuron apoptotic process GO:0043523 83 0.078
response to metal ion GO:0010038 253 0.071
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.070
response to nutrient levels GO:0031667 370 0.069
monosaccharide biosynthetic process GO:0046364 16 0.068
purine nucleotide metabolic process GO:0006163 229 0.067
response to atp GO:0033198 13 0.066
protein processing GO:0016485 68 0.063
regeneration GO:0031099 163 0.063
purine containing compound biosynthetic process GO:0072522 85 0.063
cell type specific apoptotic process GO:0097285 134 0.062
small molecule biosynthetic process GO:0044283 124 0.062
cellular response to peptide GO:1901653 133 0.062
glycosyl compound metabolic process GO:1901657 182 0.062
growth GO:0040007 165 0.061
macromolecular complex assembly GO:0065003 273 0.061
homeostatic process GO:0042592 331 0.061
regulation of rna biosynthetic process GO:2001141 381 0.060
single organism reproductive process GO:0044702 297 0.060
negative regulation of macromolecule metabolic process GO:0010605 260 0.060
cellular cation homeostasis GO:0030003 180 0.059
single organism organelle organization GO:1902589 180 0.059
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.058
purine ribonucleoside monophosphate biosynthetic process GO:0009168 20 0.057
negative regulation of neuron apoptotic process GO:0043524 45 0.056
neuron apoptotic process GO:0051402 88 0.056
response to hydrogen peroxide GO:0042542 89 0.056
carbohydrate derivative metabolic process GO:1901135 346 0.055
cellular ketone metabolic process GO:0042180 51 0.053
organic hydroxy compound metabolic process GO:1901615 115 0.053
positive regulation of phosphorus metabolic process GO:0010562 262 0.053
organonitrogen compound biosynthetic process GO:1901566 167 0.052
positive regulation of apoptotic process GO:0043065 154 0.049
transmembrane transport GO:0055085 412 0.049
organ regeneration GO:0031100 101 0.049
ion homeostasis GO:0050801 212 0.048
hepaticobiliary system development GO:0061008 90 0.048
cellular response to organonitrogen compound GO:0071417 197 0.047
cellular carbohydrate metabolic process GO:0044262 72 0.047
single organism membrane fusion GO:0044801 17 0.046
response to oxygen levels GO:0070482 265 0.045
negative regulation of rna metabolic process GO:0051253 123 0.045
purine nucleoside biosynthetic process GO:0042451 21 0.044
purine ribonucleotide metabolic process GO:0009150 227 0.043
cellular ion homeostasis GO:0006873 184 0.041
cation homeostasis GO:0055080 195 0.041
rna biosynthetic process GO:0032774 380 0.040
regulation of rna metabolic process GO:0051252 391 0.040
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.040
nucleoside monophosphate metabolic process GO:0009123 93 0.040
adp metabolic process GO:0046031 8 0.040
cellular component biogenesis GO:0044085 368 0.039
dna templated transcription initiation GO:0006352 4 0.039
nucleoside metabolic process GO:0009116 179 0.039
response to monosaccharide GO:0034284 159 0.039
post embryonic organ development GO:0048569 2 0.038
cellular homeostasis GO:0019725 252 0.038
reproduction GO:0000003 245 0.038
reproductive process GO:0022414 372 0.038
cellular chemical homeostasis GO:0055082 247 0.038
immune system process GO:0002376 204 0.038
negative regulation of gene expression GO:0010629 199 0.037
regulation of transcription dna templated GO:0006355 374 0.037
response to transition metal nanoparticle GO:1990267 122 0.036
membrane organization GO:0061024 94 0.036
protein complex assembly GO:0006461 263 0.035
response to bacterium GO:0009617 200 0.035
nucleoside triphosphate biosynthetic process GO:0009142 8 0.035
regulation of cell proliferation GO:0042127 359 0.035
response to carbohydrate GO:0009743 183 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.034
regulation of cell differentiation GO:0045595 320 0.034
cellular response to hormone stimulus GO:0032870 247 0.033
response to glucose GO:0009749 136 0.033
cellular metal ion homeostasis GO:0006875 172 0.032
purine nucleoside metabolic process GO:0042278 169 0.032
carbohydrate derivative biosynthetic process GO:1901137 124 0.032
organic acid biosynthetic process GO:0016053 83 0.032
developmental process involved in reproduction GO:0003006 159 0.032
nucleotide biosynthetic process GO:0009165 98 0.031
cellular catabolic process GO:0044248 295 0.031
organelle organization GO:0006996 266 0.031
response to molecule of bacterial origin GO:0002237 194 0.031
oxidoreduction coenzyme metabolic process GO:0006733 31 0.031
nitrogen compound transport GO:0071705 229 0.031
ion transmembrane transport GO:0034220 365 0.030
negative regulation of neuron death GO:1901215 69 0.030
regulation of protein maturation GO:1903317 50 0.030
response to external biotic stimulus GO:0043207 221 0.030
regulation of nervous system development GO:0051960 264 0.030
organelle fusion GO:0048284 17 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
tissue development GO:0009888 252 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
protein homooligomerization GO:0051260 91 0.029
sexual reproduction GO:0019953 148 0.028
membrane fusion GO:0061025 26 0.028
purine nucleoside diphosphate metabolic process GO:0009135 9 0.027
purine ribonucleoside metabolic process GO:0046128 168 0.027
regulation of system process GO:0044057 208 0.027
cell cycle phase transition GO:0044770 21 0.027
cytosolic calcium ion homeostasis GO:0051480 140 0.027
single organism behavior GO:0044708 130 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
response to cytokine GO:0034097 215 0.026
mitochondrion organization GO:0007005 35 0.026
multicellular organism reproduction GO:0032504 233 0.026
positive regulation of cell death GO:0010942 184 0.026
male gamete generation GO:0048232 99 0.026
purine ribonucleoside catabolic process GO:0046130 124 0.026
reproductive structure development GO:0048608 128 0.025
chemical homeostasis GO:0048878 292 0.025
sex differentiation GO:0007548 113 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
response to reactive oxygen species GO:0000302 120 0.025
cell cycle checkpoint GO:0000075 2 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
nucleic acid templated transcription GO:0097659 379 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
calcium ion homeostasis GO:0055074 162 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
ribose phosphate biosynthetic process GO:0046390 87 0.023
multi organism reproductive process GO:0044703 262 0.023
mitotic spindle organization GO:0007052 2 0.023
regulation of cell cycle process GO:0010564 31 0.023
response to estradiol GO:0032355 164 0.023
atp metabolic process GO:0046034 72 0.023
rna metabolic process GO:0016070 406 0.022
reproductive system development GO:0061458 128 0.022
oxidation reduction process GO:0055114 304 0.022
neuron death GO:0070997 127 0.022
glutamate catabolic process GO:0006538 1 0.022
female gonad development GO:0008585 53 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
regulation of growth GO:0040008 105 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
purine containing compound metabolic process GO:0072521 253 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.021
ribonucleoside monophosphate metabolic process GO:0009161 88 0.021
behavior GO:0007610 205 0.021
ribonucleoside triphosphate biosynthetic process GO:0009201 7 0.020
negative regulation of cell proliferation GO:0008285 119 0.020
neuron differentiation GO:0030182 368 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
myoblast fusion GO:0007520 2 0.020
response to wounding GO:0009611 254 0.020
response to insulin GO:0032868 133 0.020
transcription dna templated GO:0006351 377 0.020
mitotic dna damage checkpoint GO:0044773 1 0.020
protein complex subunit organization GO:0071822 302 0.019
regulation of cell development GO:0060284 263 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
protein nitrosylation GO:0017014 2 0.019
purine nucleoside catabolic process GO:0006152 124 0.019
response to lipopolysaccharide GO:0032496 191 0.019
epithelium development GO:0060429 96 0.019
regulation of cysteine type endopeptidase activity GO:2000116 32 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
regulation of phosphorylation GO:0042325 248 0.019
positive regulation of developmental process GO:0051094 283 0.019
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
ribonucleotide biosynthetic process GO:0009260 85 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
energy derivation by oxidation of organic compounds GO:0015980 46 0.018
ribonucleoside catabolic process GO:0042454 126 0.018
epithelial cell differentiation GO:0030855 71 0.018
response to acid chemical GO:0001101 222 0.017
regulation of carbohydrate catabolic process GO:0043470 14 0.017
positive regulation of gene expression GO:0010628 244 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.017
negative regulation of molecular function GO:0044092 133 0.017
nucleoside diphosphate metabolic process GO:0009132 14 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
metal ion transport GO:0030001 289 0.017
metal ion homeostasis GO:0055065 186 0.016
ribonucleoside monophosphate biosynthetic process GO:0009156 24 0.016
regulation of molecular function GO:0065009 398 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
regulation of ion transport GO:0043269 245 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
calcium ion transport GO:0006816 131 0.016
positive regulation of biosynthetic process GO:0009891 319 0.015
monocarboxylic acid biosynthetic process GO:0072330 48 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
spermatogenesis GO:0007283 99 0.015
negative regulation of proteolysis GO:0045861 41 0.015
protein homotetramerization GO:0051289 25 0.015
response to interleukin 1 GO:0070555 55 0.015
wound healing GO:0042060 122 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
regulation of cell growth GO:0001558 85 0.015
regulation of neuron death GO:1901214 115 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
neurological system process GO:0050877 219 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
cell cell signaling GO:0007267 335 0.014
g2 dna damage checkpoint GO:0031572 1 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.013
neuron development GO:0048666 286 0.013
response to corticosteroid GO:0031960 235 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
cell cycle GO:0007049 101 0.013
behavioral response to ethanol GO:0048149 1 0.013
purine ribonucleoside diphosphate biosynthetic process GO:0009180 9 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
female pregnancy GO:0007565 122 0.013
protein maturation GO:0051604 68 0.013
regulation of peptidase activity GO:0052547 55 0.013
cation transport GO:0006812 382 0.013
glycosyl compound biosynthetic process GO:1901659 25 0.013
cellular amine metabolic process GO:0044106 38 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
heterocycle catabolic process GO:0046700 167 0.013
mitotic cell cycle GO:0000278 49 0.012
carboxylic acid transport GO:0046942 115 0.012
head development GO:0060322 247 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
aging GO:0007568 241 0.012
negative regulation of cell death GO:0060548 229 0.012
response to glucocorticoid GO:0051384 223 0.012
alpha amino acid catabolic process GO:1901606 20 0.012
gonad development GO:0008406 104 0.012
placenta development GO:0001890 22 0.012
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 17 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
cellular amino acid biosynthetic process GO:0008652 32 0.012
macromolecular complex subunit organization GO:0043933 339 0.011
development of primary female sexual characteristics GO:0046545 56 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
neuron projection development GO:0031175 273 0.011
regulation of metal ion transport GO:0010959 118 0.011
aldehyde biosynthetic process GO:0046184 4 0.011
nucleotide catabolic process GO:0009166 139 0.011
regulation of cellular response to growth factor stimulus GO:0090287 15 0.011
development of primary sexual characteristics GO:0045137 107 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
spindle organization GO:0007051 2 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
divalent inorganic cation transport GO:0072511 134 0.011
female sex differentiation GO:0046660 59 0.011
nucleoside biosynthetic process GO:0009163 25 0.011
muscle structure development GO:0061061 87 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
positive regulation of neuron projection development GO:0010976 99 0.010
male sex differentiation GO:0046661 64 0.010
response to ketone GO:1901654 182 0.010
response to biotic stimulus GO:0009607 226 0.010
protein transmembrane transport GO:0071806 2 0.010
multi multicellular organism process GO:0044706 138 0.010
synaptic transmission GO:0007268 235 0.010
ossification GO:0001503 70 0.010
central nervous system development GO:0007417 311 0.010
cellular modified amino acid metabolic process GO:0006575 61 0.010

Tpi1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012