Rattus norvegicus

226 known processes

Tpm1

tropomyosin 1, alpha

(Aliases: Alpha-tm,Tma2,Tmsa)

Tpm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component morphogenesis GO:0032989 155 0.383
Fly
protein complex subunit organization GO:0071822 302 0.344
macromolecular complex subunit organization GO:0043933 339 0.304
cardiac muscle contraction GO:0060048 27 0.304
regulation of apoptotic process GO:0042981 335 0.279
single organism organelle organization GO:1902589 180 0.278
cellular component assembly GO:0022607 360 0.274
muscle contraction GO:0006936 88 0.271
actin filament based process GO:0030029 86 0.259
programmed cell death GO:0012501 392 0.256
response to heat GO:0009408 60 0.252
cell projection organization GO:0030030 302 0.250
response to oxygen levels GO:0070482 265 0.248
cytoskeleton organization GO:0007010 111 0.248
negative regulation of cell death GO:0060548 229 0.225
muscle system process GO:0003012 115 0.222
heart contraction GO:0060047 57 0.210
response to extracellular stimulus GO:0009991 380 0.209
cellular response to stress GO:0033554 269 0.204
stress activated protein kinase signaling cascade GO:0031098 37 0.203
apoptotic process GO:0006915 381 0.198
organelle organization GO:0006996 266 0.149
response to estrogen GO:0043627 232 0.148
response to metal ion GO:0010038 253 0.143
heart process GO:0003015 57 0.138
regulation of programmed cell death GO:0043067 341 0.134
cellular component biogenesis GO:0044085 368 0.133
nucleotide metabolic process GO:0009117 279 0.131
protein complex biogenesis GO:0070271 263 0.131
response to decreased oxygen levels GO:0036293 237 0.130
aging GO:0007568 241 0.119
intracellular signal transduction GO:0035556 314 0.118
protein complex assembly GO:0006461 263 0.117
mapk cascade GO:0000165 140 0.110
nucleoside monophosphate metabolic process GO:0009123 93 0.109
response to hypoxia GO:0001666 231 0.106
cell projection morphogenesis GO:0048858 123 0.106
Fly
negative regulation of apoptotic process GO:0043066 181 0.101
striated muscle contraction GO:0006941 44 0.099
actin cytoskeleton organization GO:0030036 73 0.098
organophosphate metabolic process GO:0019637 370 0.096
negative regulation of metabolic process GO:0009892 331 0.095
anatomical structure morphogenesis GO:0009653 298 0.094
Fly
regulation of phosphorus metabolic process GO:0051174 349 0.094
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.093
response to inorganic substance GO:0010035 377 0.093
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.087
regulation of catalytic activity GO:0050790 304 0.087
regulation of cellular component organization GO:0051128 368 0.086
regulation of cellular localization GO:0060341 263 0.085
growth GO:0040007 165 0.084
cellular response to endogenous stimulus GO:0071495 377 0.083
nucleic acid templated transcription GO:0097659 379 0.082
response to oxidative stress GO:0006979 186 0.081
cellular component movement GO:0006928 248 0.081
purine nucleotide metabolic process GO:0006163 229 0.080
single organism biosynthetic process GO:0044711 342 0.075
tissue development GO:0009888 252 0.074
signal transduction by phosphorylation GO:0023014 144 0.072
regulation of muscle contraction GO:0006937 53 0.071
regulation of nucleic acid templated transcription GO:1903506 380 0.070
protein oligomerization GO:0051259 191 0.070
ribose phosphate metabolic process GO:0019693 235 0.070
cellular response to oxygen containing compound GO:1901701 386 0.069
negative regulation of cellular metabolic process GO:0031324 281 0.069
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.067
response to nutrient levels GO:0031667 370 0.067
regulation of rna metabolic process GO:0051252 391 0.066
regulation of phosphate metabolic process GO:0019220 349 0.065
organic acid metabolic process GO:0006082 292 0.064
negative regulation of programmed cell death GO:0043069 183 0.063
cell part morphogenesis GO:0032990 123 0.063
Fly
response to temperature stimulus GO:0009266 94 0.061
regulation of rna biosynthetic process GO:2001141 381 0.061
neuron development GO:0048666 286 0.060
Fly
cellular response to nitrogen compound GO:1901699 210 0.060
response to estradiol GO:0032355 164 0.060
biological adhesion GO:0022610 110 0.059
muscle structure development GO:0061061 87 0.059
carboxylic acid metabolic process GO:0019752 289 0.057
cell morphogenesis GO:0000902 142 0.057
Fly
cold acclimation GO:0009631 1 0.056
rna biosynthetic process GO:0032774 380 0.055
neuron projection morphogenesis GO:0048812 122 0.055
Fly
response to peptide hormone GO:0043434 278 0.055
regulation of transcription dna templated GO:0006355 374 0.054
positive regulation of cellular biosynthetic process GO:0031328 295 0.054
protein phosphorylation GO:0006468 345 0.054
positive regulation of phosphate metabolic process GO:0045937 262 0.054
actin filament organization GO:0007015 42 0.053
neuron death GO:0070997 127 0.053
ribonucleoside monophosphate metabolic process GO:0009161 88 0.052
neuron differentiation GO:0030182 368 0.051
Fly
carbohydrate derivative metabolic process GO:1901135 346 0.051
purine nucleoside triphosphate metabolic process GO:0009144 141 0.051
transcription dna templated GO:0006351 377 0.051
blood circulation GO:0008015 183 0.051
cellular amino acid metabolic process GO:0006520 107 0.051
regeneration GO:0031099 163 0.051
actomyosin structure organization GO:0031032 22 0.050
response to bacterium GO:0009617 200 0.050
cellular response to abiotic stimulus GO:0071214 85 0.049
actin filament based movement GO:0030048 16 0.049
regulation of molecular function GO:0065009 398 0.049
positive regulation of signaling GO:0023056 270 0.049
response to peptide GO:1901652 292 0.048
heart morphogenesis GO:0003007 3 0.048
purine nucleoside catabolic process GO:0006152 124 0.048
positive regulation of biosynthetic process GO:0009891 319 0.048
macromolecular complex assembly GO:0065003 273 0.047
response to hydrogen peroxide GO:0042542 89 0.047
neuron apoptotic process GO:0051402 88 0.047
catabolic process GO:0009056 351 0.046
oxoacid metabolic process GO:0043436 290 0.046
positive regulation of phosphorus metabolic process GO:0010562 262 0.046
nucleoside phosphate metabolic process GO:0006753 283 0.046
ribonucleoside triphosphate metabolic process GO:0009199 141 0.046
cell adhesion GO:0007155 110 0.045
cellular response to organonitrogen compound GO:0071417 197 0.045
response to reactive oxygen species GO:0000302 120 0.045
cell morphogenesis involved in differentiation GO:0000904 119 0.044
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.044
purine nucleoside metabolic process GO:0042278 169 0.044
cellular catabolic process GO:0044248 295 0.044
response to mechanical stimulus GO:0009612 134 0.044
positive regulation of cell communication GO:0010647 271 0.043
ribose phosphate biosynthetic process GO:0046390 87 0.042
positive regulation of rna metabolic process GO:0051254 203 0.042
rna metabolic process GO:0016070 406 0.042
cell type specific apoptotic process GO:0097285 134 0.042
ribonucleoside metabolic process GO:0009119 174 0.042
positive regulation of rna biosynthetic process GO:1902680 197 0.042
organic cyclic compound catabolic process GO:1901361 175 0.042
anatomical structure formation involved in morphogenesis GO:0048646 83 0.040
organonitrogen compound biosynthetic process GO:1901566 167 0.040
response to wounding GO:0009611 254 0.040
central nervous system development GO:0007417 311 0.040
Rat
cellular response to lipid GO:0071396 201 0.040
ribonucleotide metabolic process GO:0009259 231 0.040
ribonucleotide catabolic process GO:0009261 136 0.039
single organism reproductive process GO:0044702 297 0.039
Fly
response to glucocorticoid GO:0051384 223 0.039
cellular homeostasis GO:0019725 252 0.038
intracellular transport GO:0046907 185 0.038
regulation of neuron apoptotic process GO:0043523 83 0.037
macromolecule localization GO:0033036 252 0.037
Fly
regulation of phosphorylation GO:0042325 248 0.037
regulation of purine nucleotide metabolic process GO:1900542 115 0.037
axon development GO:0061564 96 0.037
positive regulation of molecular function GO:0044093 230 0.036
regulation of muscle system process GO:0090257 79 0.036
purine ribonucleotide metabolic process GO:0009150 227 0.036
nucleoside metabolic process GO:0009116 179 0.036
circulatory system development GO:0072359 134 0.036
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.036
cellular ketone metabolic process GO:0042180 51 0.036
response to corticosteroid GO:0031960 235 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.035
muscle tissue development GO:0060537 58 0.035
purine ribonucleoside metabolic process GO:0046128 168 0.035
positive regulation of gene expression GO:0010628 244 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
purine containing compound catabolic process GO:0072523 138 0.035
reactive oxygen species metabolic process GO:0072593 37 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.034
regulation of protein metabolic process GO:0051246 289 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
positive regulation of signal transduction GO:0009967 175 0.034
response to starvation GO:0042594 59 0.034
cellular response to organic cyclic compound GO:0071407 202 0.034
response to tumor necrosis factor GO:0034612 56 0.034
cell cycle GO:0007049 101 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.033
Fly
response to growth factor GO:0070848 189 0.032
cellular response to peptide hormone stimulus GO:0071375 120 0.032
amine metabolic process GO:0009308 38 0.032
cellular ion homeostasis GO:0006873 184 0.032
positive regulation of programmed cell death GO:0043068 157 0.032
cellular amine metabolic process GO:0044106 38 0.032
response to insulin GO:0032868 133 0.032
regulation of signal transduction GO:0009966 318 0.031
response to acid chemical GO:0001101 222 0.031
regulation of intracellular signal transduction GO:1902531 218 0.031
cell migration GO:0016477 197 0.031
neuron projection development GO:0031175 273 0.031
Fly
actin filament bundle organization GO:0061572 19 0.031
cellular macromolecule localization GO:0070727 122 0.031
Fly
single organism catabolic process GO:0044712 283 0.031
secretion GO:0046903 307 0.031
positive regulation of apoptotic process GO:0043065 154 0.031
organ morphogenesis GO:0009887 75 0.030
positive regulation of cell death GO:0010942 184 0.030
negative regulation of cellular biosynthetic process GO:0031327 161 0.029
protein homooligomerization GO:0051260 91 0.029
cardiac ventricle development GO:0003231 1 0.029
cellular cation homeostasis GO:0030003 180 0.029
organic substance catabolic process GO:1901575 316 0.029
regulation of establishment of planar polarity GO:0090175 2 0.029
stress activated mapk cascade GO:0051403 35 0.029
head development GO:0060322 247 0.028
Rat
reproductive process GO:0022414 372 0.028
Fly
positive regulation of cell proliferation GO:0008284 249 0.028
organ regeneration GO:0031100 101 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.028
muscle cell differentiation GO:0042692 52 0.028
response to other organism GO:0051707 220 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
regulation of organelle organization GO:0033043 80 0.028
muscle filament sliding GO:0030049 2 0.028
homeostatic process GO:0042592 331 0.027
aromatic compound catabolic process GO:0019439 168 0.027
regulation of purine nucleotide catabolic process GO:0033121 65 0.027
response to nutrient GO:0007584 248 0.027
purine nucleoside monophosphate metabolic process GO:0009126 84 0.027
response to external biotic stimulus GO:0043207 221 0.027
cell growth GO:0016049 104 0.027
carbohydrate derivative catabolic process GO:1901136 147 0.026
positive regulation of protein metabolic process GO:0051247 178 0.026
generation of precursor metabolites and energy GO:0006091 62 0.026
oxidation reduction process GO:0055114 304 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
ribonucleoside triphosphate catabolic process GO:0009203 122 0.026
nucleoside phosphate catabolic process GO:1901292 140 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
actin mediated cell contraction GO:0070252 12 0.026
cardiac chamber development GO:0003205 1 0.025
response to radiation GO:0009314 137 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.025
reproduction GO:0000003 245 0.025
Fly
regulation of mapk cascade GO:0043408 116 0.025
regulation of neuron differentiation GO:0045664 208 0.025
response to amino acid GO:0043200 75 0.025
cellular response to growth factor stimulus GO:0071363 162 0.025
organic hydroxy compound metabolic process GO:1901615 115 0.025
response to cytokine GO:0034097 215 0.025
positive regulation of intracellular signal transduction GO:1902533 138 0.024
regulation of cell projection organization GO:0031344 175 0.024
Fly
nucleoside triphosphate catabolic process GO:0009143 123 0.024
defense response GO:0006952 194 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
enzyme linked receptor protein signaling pathway GO:0007167 116 0.024
nucleoside triphosphate metabolic process GO:0009141 144 0.024
regulation of cell differentiation GO:0045595 320 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
regulation of system process GO:0044057 208 0.023
cardiac muscle tissue morphogenesis GO:0055008 1 0.023
regulation of membrane potential GO:0042391 110 0.023
response to ethanol GO:0045471 162 0.023
regulation of actin filament based process GO:0032970 42 0.023
response to biotic stimulus GO:0009607 226 0.023
muscle organ morphogenesis GO:0048644 1 0.023
single organism membrane organization GO:0044802 74 0.023
localization of cell GO:0051674 202 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
cellular protein localization GO:0034613 122 0.023
protein transport GO:0015031 132 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
response to ionizing radiation GO:0010212 59 0.023
negative regulation of gene expression GO:0010629 199 0.023
purine ribonucleotide catabolic process GO:0009154 136 0.023
positive regulation of transport GO:0051050 245 0.022
axonogenesis GO:0007409 71 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.022
nucleotide catabolic process GO:0009166 139 0.022
establishment of protein localization GO:0045184 141 0.022
regulation of catabolic process GO:0009894 113 0.022
regulation of hydrolase activity GO:0051336 143 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
regulation of cellular response to stress GO:0080135 49 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
organelle assembly GO:0070925 22 0.022
protein localization GO:0008104 191 0.022
regulation of cellular catabolic process GO:0031329 101 0.022
response to gamma radiation GO:0010332 24 0.021
cardiovascular system development GO:0072358 134 0.021
Fly
response to interleukin 1 GO:0070555 55 0.021
microtubule polymerization or depolymerization GO:0031109 13 0.021
striated muscle tissue development GO:0014706 58 0.021
positive regulation of developmental process GO:0051094 283 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
circulatory system process GO:0003013 183 0.021
purine containing compound metabolic process GO:0072521 253 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
response to lithium ion GO:0010226 28 0.021
proteolysis GO:0006508 175 0.021
regulation of reactive oxygen species metabolic process GO:2000377 26 0.021
organophosphate catabolic process GO:0046434 148 0.020
cell cell junction organization GO:0045216 20 0.020
energy derivation by oxidation of organic compounds GO:0015980 46 0.020
synaptic transmission GO:0007268 235 0.020
striated muscle cell development GO:0055002 26 0.020
cellular chemical homeostasis GO:0055082 247 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.020
regulation of response to stress GO:0080134 126 0.020
regulation of protein modification process GO:0031399 194 0.020
regulation of nucleotide metabolic process GO:0006140 117 0.020
cellular response to peptide GO:1901653 133 0.020
cellular response to oxidative stress GO:0034599 76 0.020
negative regulation of catalytic activity GO:0043086 103 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
protein heterooligomerization GO:0051291 89 0.020
organic acid biosynthetic process GO:0016053 83 0.020
secretion by cell GO:0032940 248 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
regulation of secretion by cell GO:1903530 208 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
Fly
cell motility GO:0048870 202 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
muscle tissue morphogenesis GO:0060415 1 0.019
chemical homeostasis GO:0048878 292 0.019
regulation of neuron death GO:1901214 115 0.019
response to hexose GO:0009746 144 0.019
regulation of cell proliferation GO:0042127 359 0.019
response to cold GO:0009409 29 0.019
cell cycle checkpoint GO:0000075 2 0.019
response to vitamin GO:0033273 131 0.018
organic acid transport GO:0015849 116 0.018
regulation of nervous system development GO:0051960 264 0.018
ribonucleoside catabolic process GO:0042454 126 0.018
single organism intracellular transport GO:1902582 166 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
positive regulation of transcription factor import into nucleus GO:0042993 4 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
axis specification GO:0009798 4 0.018
Fly
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
adult locomotory behavior GO:0008344 4 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.018
ion homeostasis GO:0050801 212 0.018
multi organism reproductive process GO:0044703 262 0.018
Fly
carboxylic acid transport GO:0046942 115 0.018
action potential GO:0001508 54 0.018
membrane organization GO:0061024 94 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
negative regulation of phosphorus metabolic process GO:0010563 80 0.018
regulation of neuron projection development GO:0010975 161 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
muscle organ development GO:0007517 50 0.017
establishment of planar polarity GO:0001736 1 0.017
multicellular organism reproduction GO:0032504 233 0.017
Fly
positive regulation of protein modification process GO:0031401 142 0.017
muscle cell proliferation GO:0033002 84 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
regulation of neurogenesis GO:0050767 247 0.017
anterior posterior pattern specification GO:0009952 1 0.017
Fly
dna metabolic process GO:0006259 96 0.017
salivary gland morphogenesis GO:0007435 1 0.017
single organism carbohydrate metabolic process GO:0044723 118 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
necroptotic process GO:0070266 2 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
regulation of stress activated mapk cascade GO:0032872 23 0.016
cellular response to acid chemical GO:0071229 75 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
gastrulation GO:0007369 2 0.016
regulation of hormone levels GO:0010817 187 0.016
regulation of protein localization GO:0032880 81 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
actin filament bundle assembly GO:0051017 19 0.016
purine nucleoside triphosphate catabolic process GO:0009146 122 0.016
negative regulation of transport GO:0051051 136 0.016
atp metabolic process GO:0046034 72 0.016
immune response GO:0006955 104 0.016
anion transport GO:0006820 178 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
wound healing GO:0042060 122 0.016
regulation of synaptic transmission GO:0050804 141 0.016
ossification GO:0001503 70 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
regulation of stem cell differentiation GO:2000736 2 0.016
heterocycle catabolic process GO:0046700 167 0.016
positive regulation of organelle organization GO:0010638 48 0.016
cellular response to electrical stimulus GO:0071257 8 0.015
fatty acid metabolic process GO:0006631 99 0.015
gland development GO:0048732 155 0.015
cellular response to tumor necrosis factor GO:0071356 46 0.015
immune system process GO:0002376 204 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
regulation of cell growth GO:0001558 85 0.015
metal ion homeostasis GO:0055065 186 0.015
response to electrical stimulus GO:0051602 56 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
regulation of cellular component movement GO:0051270 150 0.015
cellular response to insulin stimulus GO:0032869 81 0.015
response to glucose GO:0009749 136 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.015
cellular glucan metabolic process GO:0006073 23 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
peptidyl amino acid modification GO:0018193 126 0.015
chromosome segregation GO:0007059 2 0.015
atp catabolic process GO:0006200 54 0.015
response to ketone GO:1901654 182 0.015
jnk cascade GO:0007254 28 0.015
negative regulation of cell cycle phase transition GO:1901988 4 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
response to organophosphorus GO:0046683 102 0.014
negative regulation of growth GO:0045926 37 0.014
glucan metabolic process GO:0044042 23 0.014
camera type eye development GO:0043010 48 0.014
rhythmic process GO:0048511 156 0.014
response to monosaccharide GO:0034284 159 0.014
single organism behavior GO:0044708 130 0.014
response to carbohydrate GO:0009743 183 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
heart development GO:0007507 72 0.014
Fly
regulation of intracellular transport GO:0032386 65 0.014
carboxylic acid biosynthetic process GO:0046394 83 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
spermatogenesis GO:0007283 99 0.014
lipid metabolic process GO:0006629 283 0.014
positive regulation of neuron apoptotic process GO:0043525 33 0.014
cation transport GO:0006812 382 0.014
regulation of cell cycle GO:0051726 73 0.014
amide transport GO:0042886 105 0.014
calcium ion homeostasis GO:0055074 162 0.014
cellular component assembly involved in morphogenesis GO:0010927 17 0.014
response to calcium ion GO:0051592 59 0.014
cytokine production GO:0001816 61 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
negative regulation of neuron differentiation GO:0045665 62 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
cell cycle process GO:0022402 57 0.013
lipid localization GO:0010876 62 0.013
embryonic pattern specification GO:0009880 1 0.013
Fly
defense response to fungus GO:0050832 1 0.013
striated muscle cell differentiation GO:0051146 39 0.013
positive regulation of cell development GO:0010720 176 0.013
negative regulation of cell communication GO:0010648 158 0.013
cation homeostasis GO:0055080 195 0.013
negative regulation of neuron apoptotic process GO:0043524 45 0.013
regulation of cell cycle g2 m phase transition GO:1902749 4 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
skeletal muscle organ development GO:0060538 33 0.013
regulation of secretion GO:0051046 224 0.013
peptide transport GO:0015833 97 0.013
carbohydrate metabolic process GO:0005975 130 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
glycogen biosynthetic process GO:0005978 15 0.012
polysaccharide metabolic process GO:0005976 25 0.012
positive regulation of endothelial cell migration GO:0010595 4 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
central nervous system neuron axonogenesis GO:0021955 1 0.012
brain development GO:0007420 247 0.012
Rat
purine ribonucleoside catabolic process GO:0046130 124 0.012
positive regulation of protein transport GO:0051222 41 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
cellular response to alcohol GO:0097306 87 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
nucleoside monophosphate catabolic process GO:0009125 56 0.012
vesicle mediated transport GO:0016192 181 0.012
cellular lipid metabolic process GO:0044255 208 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
glycogen metabolic process GO:0005977 23 0.012
protein maturation GO:0051604 68 0.012
hepaticobiliary system development GO:0061008 90 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
dna integrity checkpoint GO:0031570 2 0.012
ras protein signal transduction GO:0007265 29 0.012
syncytium formation GO:0006949 4 0.012
salivary gland development GO:0007431 3 0.012
chemotaxis GO:0006935 66 0.012
positive regulation of neuron death GO:1901216 43 0.012
cell activation GO:0001775 97 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
regulation of anatomical structure size GO:0090066 135 0.012

Tpm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.520
muscular disease DOID:0080000 0 0.520
heart disease DOID:114 0 0.520
cardiomyopathy DOID:0050700 0 0.520
disease of anatomical entity DOID:7 0 0.520
intrinsic cardiomyopathy DOID:0060036 0 0.520
cardiovascular system disease DOID:1287 0 0.520
musculoskeletal system disease DOID:17 0 0.520
muscle tissue disease DOID:66 0 0.520
dilated cardiomyopathy DOID:12930 0 0.085
sensory system disease DOID:0050155 0 0.064
nervous system disease DOID:863 0 0.064
disease of metabolism DOID:0014667 0 0.031
inherited metabolic disorder DOID:655 0 0.026
eye and adnexa disease DOID:1492 0 0.018
carbohydrate metabolic disorder DOID:2978 0 0.015