Rattus norvegicus

0 known processes

Tpm2

tropomyosin 2, beta

(Aliases: MGC109519)

Tpm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of atp catabolic process GO:1903290 2 0.925
coagulation GO:0050817 28 0.772
anterior posterior pattern specification GO:0009952 1 0.765
Fly
cytoskeleton organization GO:0007010 111 0.468
Rat
cellular component movement GO:0006928 248 0.402
Rat
protein complex subunit organization GO:0071822 302 0.288
Rat
negative regulation of nucleotide metabolic process GO:0045980 23 0.279
cell activation GO:0001775 97 0.253
blood coagulation GO:0007596 26 0.229
actin mediated cell contraction GO:0070252 12 0.225
Rat
wound healing GO:0042060 122 0.215
Rat
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.212
Human Rat
actin cytoskeleton organization GO:0030036 73 0.188
Rat
neuron development GO:0048666 286 0.188
Fly
response to metal ion GO:0010038 253 0.167
tube formation GO:0035148 3 0.167
elastic fiber assembly GO:0048251 1 0.158
ribonucleoside catabolic process GO:0042454 126 0.148
Human Rat
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.141
Human Rat
muscle contraction GO:0006936 88 0.140
Rat
negative regulation of atpase activity GO:0032780 2 0.139
atp catabolic process GO:0006200 54 0.132
Human Rat
regulation of atpase activity GO:0043462 7 0.124
Human Rat
cell adhesion GO:0007155 110 0.123
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.121
Human Rat
single organism organelle organization GO:1902589 180 0.121
Rat
actin filament based process GO:0030029 86 0.120
Rat
single organism catabolic process GO:0044712 283 0.119
Human Rat
locomotion GO:0040011 237 0.116
Rat
nucleoside monophosphate metabolic process GO:0009123 93 0.116
Human Rat
immune response GO:0006955 104 0.108
regulation of phosphorus metabolic process GO:0051174 349 0.108
Human Rat
extracellular matrix organization GO:0030198 13 0.107
cell cycle GO:0007049 101 0.107
purine ribonucleoside catabolic process GO:0046130 124 0.105
Human Rat
cell projection organization GO:0030030 302 0.103
Rat Fly
ribose phosphate metabolic process GO:0019693 235 0.097
Human Rat
response to estrogen GO:0043627 232 0.092
response to ketone GO:1901654 182 0.092
neuron projection development GO:0031175 273 0.087
Fly
blood circulation GO:0008015 183 0.086
Rat
gastrulation GO:0007369 2 0.086
organelle organization GO:0006996 266 0.084
Rat
cellular response to organic cyclic compound GO:0071407 202 0.083
cellular catabolic process GO:0044248 295 0.081
Human Rat
regulation of hydrolase activity GO:0051336 143 0.081
Human Rat
purine nucleoside catabolic process GO:0006152 124 0.081
Human Rat
purine ribonucleotide metabolic process GO:0009150 227 0.080
Human Rat
nucleotide metabolic process GO:0009117 279 0.080
Human Rat
actin crosslink formation GO:0051764 3 0.078
macromolecular complex subunit organization GO:0043933 339 0.078
Rat
regulation of actin filament based process GO:0032970 42 0.076
Rat
platelet aggregation GO:0070527 4 0.071
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.071
purine nucleoside triphosphate catabolic process GO:0009146 122 0.071
Human Rat
response to radiation GO:0009314 137 0.070
nucleoside metabolic process GO:0009116 179 0.069
Human Rat
regulation of molecular function GO:0065009 398 0.069
Human Rat
atp metabolic process GO:0046034 72 0.068
Human Rat
heterocycle catabolic process GO:0046700 167 0.068
Human Rat
tissue development GO:0009888 252 0.067
carbohydrate derivative metabolic process GO:1901135 346 0.066
Human Rat
digestive tract development GO:0048565 39 0.064
purine containing compound metabolic process GO:0072521 253 0.064
Human Rat
metal ion transport GO:0030001 289 0.063
response to wounding GO:0009611 254 0.063
Rat
anatomical structure morphogenesis GO:0009653 298 0.063
Fly
actin filament based movement GO:0030048 16 0.062
Rat
heart morphogenesis GO:0003007 3 0.062
single organism cell adhesion GO:0098602 46 0.062
negative regulation of purine nucleotide metabolic process GO:1900543 23 0.062
regulation of purine nucleotide metabolic process GO:1900542 115 0.060
Human Rat
muscle system process GO:0003012 115 0.060
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.059
Human Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.055
Human Rat
organic cyclic compound catabolic process GO:1901361 175 0.055
Human Rat
response to hexose GO:0009746 144 0.055
nucleoside monophosphate catabolic process GO:0009125 56 0.055
Human Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.054
Human Rat
epithelial cell differentiation GO:0030855 71 0.053
ribonucleoside metabolic process GO:0009119 174 0.052
Human Rat
ribonucleoside monophosphate metabolic process GO:0009161 88 0.051
Human Rat
catabolic process GO:0009056 351 0.051
Human Rat
response to peptide hormone GO:0043434 278 0.048
negative regulation of molecular function GO:0044092 133 0.047
response to inorganic substance GO:0010035 377 0.047
regulation of nucleotide metabolic process GO:0006140 117 0.047
Human Rat
response to corticosteroid GO:0031960 235 0.046
regulation of neuron projection development GO:0010975 161 0.046
regulation of purine nucleotide catabolic process GO:0033121 65 0.046
Human Rat
regulation of cellular component organization GO:0051128 368 0.046
Rat Fly
purine nucleotide catabolic process GO:0006195 136 0.044
Human Rat
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.044
Fly
negative regulation of metabolic process GO:0009892 331 0.044
regeneration GO:0031099 163 0.044
regulation of metal ion transport GO:0010959 118 0.044
regulation of rna biosynthetic process GO:2001141 381 0.044
regulation of cellular catabolic process GO:0031329 101 0.043
Human Rat
organonitrogen compound catabolic process GO:1901565 179 0.043
Human Rat
single organismal cell cell adhesion GO:0016337 42 0.043
purine containing compound catabolic process GO:0072523 138 0.043
Human Rat
developmental process involved in reproduction GO:0003006 159 0.043
Fly
ribonucleoside triphosphate catabolic process GO:0009203 122 0.042
Human Rat
cation transport GO:0006812 382 0.041
carboxylic acid metabolic process GO:0019752 289 0.041
response to carbohydrate GO:0009743 183 0.040
response to bacterium GO:0009617 200 0.039
regulation of neurogenesis GO:0050767 247 0.039
cellular component biogenesis GO:0044085 368 0.039
Rat Fly
neuron differentiation GO:0030182 368 0.036
Fly
response to other organism GO:0051707 220 0.036
response to peptide GO:1901652 292 0.036
homotypic cell cell adhesion GO:0034109 8 0.036
negative regulation of phosphate metabolic process GO:0045936 80 0.036
aging GO:0007568 241 0.036
regulation of body fluid levels GO:0050878 90 0.035
mrna transcription from rna polymerase ii promoter GO:0042789 1 0.034
heart contraction GO:0060047 57 0.034
Rat
circulatory system development GO:0072359 134 0.034
Fly
response to mechanical stimulus GO:0009612 134 0.034
homeostatic process GO:0042592 331 0.033
regulation of catabolic process GO:0009894 113 0.033
Human Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.033
skeletal muscle fiber adaptation GO:0043503 1 0.033
ribonucleoside monophosphate catabolic process GO:0009158 55 0.032
Human Rat
defense response GO:0006952 194 0.032
regulation of nucleotide catabolic process GO:0030811 65 0.032
Human Rat
oxoacid metabolic process GO:0043436 290 0.032
regulation of cellular localization GO:0060341 263 0.032
cellular component morphogenesis GO:0032989 155 0.032
Fly
single organism biosynthetic process GO:0044711 342 0.032
response to oxygen levels GO:0070482 265 0.031
response to extracellular stimulus GO:0009991 380 0.031
programmed cell death GO:0012501 392 0.031
regulation of cell projection organization GO:0031344 175 0.031
Fly
response to growth factor GO:0070848 189 0.030
purine nucleoside metabolic process GO:0042278 169 0.029
Human Rat
maternal process involved in female pregnancy GO:0060135 38 0.028
multi organism reproductive process GO:0044703 262 0.028
Fly
cellular ion homeostasis GO:0006873 184 0.028
platelet activation GO:0030168 8 0.028
organic acid metabolic process GO:0006082 292 0.027
cellular homeostasis GO:0019725 252 0.027
nucleoside triphosphate catabolic process GO:0009143 123 0.027
Human Rat
striated muscle contraction GO:0006941 44 0.027
Rat
reproductive process GO:0022414 372 0.027
Fly
organophosphate metabolic process GO:0019637 370 0.027
Human Rat
apoptotic process GO:0006915 381 0.026
regulation of multicellular organismal development GO:2000026 376 0.025
positive regulation of apoptotic process GO:0043065 154 0.025
ion homeostasis GO:0050801 212 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
cytoskeleton dependent cytokinesis GO:0061640 2 0.024
muscle structure development GO:0061061 87 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
intracellular transport GO:0046907 185 0.024
response to transition metal nanoparticle GO:1990267 122 0.023
response to glucocorticoid GO:0051384 223 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.023
Human Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
response to fibroblast growth factor GO:0071774 29 0.023
cell type specific apoptotic process GO:0097285 134 0.023
nucleotide catabolic process GO:0009166 139 0.023
Human Rat
carboxylic acid biosynthetic process GO:0046394 83 0.023
purine ribonucleoside metabolic process GO:0046128 168 0.022
Human Rat
purine nucleotide metabolic process GO:0006163 229 0.022
Human Rat
negative regulation of cell death GO:0060548 229 0.022
head development GO:0060322 247 0.022
Rat
aromatic compound catabolic process GO:0019439 168 0.022
Human Rat
single organism reproductive process GO:0044702 297 0.022
Fly
actin filament organization GO:0007015 42 0.022
Rat
anatomical structure formation involved in morphogenesis GO:0048646 83 0.022
negative regulation of response to wounding GO:1903035 23 0.021
epithelium development GO:0060429 96 0.021
neuron projection regeneration GO:0031102 35 0.021
central nervous system development GO:0007417 311 0.021
Rat
organic acid biosynthetic process GO:0016053 83 0.021
organ regeneration GO:0031100 101 0.021
chemical homeostasis GO:0048878 292 0.021
nitrogen compound transport GO:0071705 229 0.021
purine nucleoside monophosphate metabolic process GO:0009126 84 0.020
Human Rat
bmp signaling pathway GO:0030509 4 0.020
response to zinc ion GO:0010043 39 0.020
cellular ketone metabolic process GO:0042180 51 0.020
regulation of catalytic activity GO:0050790 304 0.020
Human Rat
secretion by cell GO:0032940 248 0.020
regulation of nervous system development GO:0051960 264 0.020
signal release GO:0023061 145 0.020
macromolecular complex assembly GO:0065003 273 0.020
Rat
reproduction GO:0000003 245 0.020
Fly
cellular amine metabolic process GO:0044106 38 0.020
transmembrane transport GO:0055085 412 0.020
protein complex biogenesis GO:0070271 263 0.020
Rat
regulation of hormone levels GO:0010817 187 0.020
lipid biosynthetic process GO:0008610 128 0.019
cell motility GO:0048870 202 0.019
Rat
protein oligomerization GO:0051259 191 0.019
calcium ion transport into cytosol GO:0060402 38 0.019
divalent inorganic cation transport GO:0072511 134 0.019
cellular chemical homeostasis GO:0055082 247 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
response to glucose GO:0009749 136 0.019
positive regulation of cell communication GO:0010647 271 0.019
metal ion homeostasis GO:0055065 186 0.019
positive regulation of transport GO:0051050 245 0.019
regulation of neuron differentiation GO:0045664 208 0.019
cellular macromolecule localization GO:0070727 122 0.019
Fly
positive regulation of ion transport GO:0043270 94 0.019
regulation of hormone secretion GO:0046883 106 0.019
response to biotic stimulus GO:0009607 226 0.019
response to amino acid GO:0043200 75 0.019
regulation of secretion GO:0051046 224 0.018
lipid metabolic process GO:0006629 283 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
Fly
cellular response to oxygen containing compound GO:1901701 386 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
Rat
response to reactive oxygen species GO:0000302 120 0.018
response to calcium ion GO:0051592 59 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
localization of cell GO:0051674 202 0.017
Rat
cellular component assembly GO:0022607 360 0.017
Rat Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
Human Rat
regulation of cellular amine metabolic process GO:0033238 8 0.017
rhythmic process GO:0048511 156 0.017
muscle filament sliding GO:0030049 2 0.017
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
unsaturated fatty acid metabolic process GO:0033559 39 0.017
anion transport GO:0006820 178 0.017
regulation of programmed cell death GO:0043067 341 0.017
nucleoside catabolic process GO:0009164 126 0.017
Human Rat
positive regulation of nervous system development GO:0051962 178 0.017
response to ethanol GO:0045471 162 0.017
response to nutrient levels GO:0031667 370 0.017
protein heterooligomerization GO:0051291 89 0.017
negative regulation of response to external stimulus GO:0032102 37 0.016
intracellular signal transduction GO:0035556 314 0.016
negative regulation of secretion GO:0051048 82 0.016
ion transmembrane transport GO:0034220 365 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
fatty acid derivative biosynthetic process GO:1901570 18 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
cellular response to lipid GO:0071396 201 0.016
regulation of cell differentiation GO:0045595 320 0.016
prostate gland morphogenesis GO:0060512 2 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
Rat
epithelial cell morphogenesis GO:0003382 4 0.016
regulation of cell development GO:0060284 263 0.016
macromolecule localization GO:0033036 252 0.016
Fly
cellular protein localization GO:0034613 122 0.016
amine metabolic process GO:0009308 38 0.016
cellular response to glucocorticoid stimulus GO:0071385 68 0.016
rna metabolic process GO:0016070 406 0.016
regulation of phosphate metabolic process GO:0019220 349 0.015
Human Rat
protein complex assembly GO:0006461 263 0.015
Rat
cellular response to endogenous stimulus GO:0071495 377 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
single organism membrane organization GO:0044802 74 0.015
calcium ion transport GO:0006816 131 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
regulation of homotypic cell cell adhesion GO:0034110 4 0.015
hemostasis GO:0007599 26 0.015
secretion GO:0046903 307 0.015
reproductive structure development GO:0048608 128 0.015
camera type eye development GO:0043010 48 0.015
negative regulation of gene expression GO:0010629 199 0.015
cytosolic calcium ion transport GO:0060401 39 0.015
regulation of bmp signaling pathway GO:0030510 2 0.015
icosanoid metabolic process GO:0006690 38 0.015
organophosphate biosynthetic process GO:0090407 143 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
response to axon injury GO:0048678 59 0.014
blood vessel development GO:0001568 69 0.014
response to testosterone GO:0033574 55 0.014
regulation of response to wounding GO:1903034 69 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
amide transport GO:0042886 105 0.014
single organism intracellular transport GO:1902582 166 0.014
embryonic pattern specification GO:0009880 1 0.014
Fly
organonitrogen compound biosynthetic process GO:1901566 167 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
regulation of transmembrane transport GO:0034762 122 0.014
striated muscle tissue development GO:0014706 58 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
response to external biotic stimulus GO:0043207 221 0.014
response to monosaccharide GO:0034284 159 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
gamete generation GO:0007276 124 0.014
Fly
purine ribonucleotide catabolic process GO:0009154 136 0.014
Human Rat
cell matrix adhesion GO:0007160 19 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
axis specification GO:0009798 4 0.014
Fly
regulation of ion transport GO:0043269 245 0.014
rna biosynthetic process GO:0032774 380 0.014
regulation of transcription dna templated GO:0006355 374 0.013
connective tissue development GO:0061448 33 0.013
cellular lipid metabolic process GO:0044255 208 0.013
multicellular organism growth GO:0035264 1 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
Human Rat
glycosyl compound catabolic process GO:1901658 126 0.013
Human Rat
regulation of protein metabolic process GO:0051246 289 0.013
mitotic cell cycle GO:0000278 49 0.013
response to estradiol GO:0032355 164 0.013
cellular response to alcohol GO:0097306 87 0.013
vascular process in circulatory system GO:0003018 96 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
regulation of erk1 and erk2 cascade GO:0070372 41 0.013
response to electrical stimulus GO:0051602 56 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
cation transmembrane transport GO:0098655 263 0.013
single organism behavior GO:0044708 130 0.013
ras protein signal transduction GO:0007265 29 0.013
positive regulation of synaptic transmission GO:0050806 62 0.013
regulation of rna metabolic process GO:0051252 391 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
Rat
small molecule biosynthetic process GO:0044283 124 0.013
cellular response to growth factor stimulus GO:0071363 162 0.012
protein phosphorylation GO:0006468 345 0.012
positive regulation of homeostatic process GO:0032846 49 0.012
response to decreased oxygen levels GO:0036293 237 0.012
developmental growth GO:0048589 100 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
Rat
regulation of ion transmembrane transport GO:0034765 121 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
protein homooligomerization GO:0051260 91 0.012
cellular response to stress GO:0033554 269 0.012
negative regulation of neuron projection development GO:0010977 46 0.012
stress activated mapk cascade GO:0051403 35 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
peptide hormone secretion GO:0030072 84 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
glucose homeostasis GO:0042593 75 0.012
regulation of peptidase activity GO:0052547 55 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
response to acid chemical GO:0001101 222 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
embryo development GO:0009790 49 0.012
Fly
reproductive system development GO:0061458 128 0.012
tube development GO:0035295 89 0.012
regulation of transporter activity GO:0032409 50 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
divalent metal ion transport GO:0070838 132 0.011
response to toxic substance GO:0009636 133 0.011
positive regulation of gene expression GO:0010628 244 0.011
regulation of cell proliferation GO:0042127 359 0.011
cell morphogenesis GO:0000902 142 0.011
Fly
negative regulation of catalytic activity GO:0043086 103 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
Human Rat
proteolysis GO:0006508 175 0.011
negative regulation of hydrolase activity GO:0051346 52 0.011
cardiac cell development GO:0055006 16 0.011
regulation of response to stress GO:0080134 126 0.011
monocarboxylic acid biosynthetic process GO:0072330 48 0.011
regulation of erythrocyte aggregation GO:0034118 1 0.011
biological adhesion GO:0022610 110 0.011
Rat
regulation of neuron death GO:1901214 115 0.011
regulation of calcium ion transport GO:0051924 77 0.011
cellular cation homeostasis GO:0030003 180 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
Human Rat
cell cell signaling GO:0007267 335 0.011
nucleic acid templated transcription GO:0097659 379 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of atp metabolic process GO:1903578 9 0.011
Human Rat
positive regulation of multicellular organismal process GO:0051240 387 0.011
male gamete generation GO:0048232 99 0.011
positive regulation of protein modification process GO:0031401 142 0.011
sexual reproduction GO:0019953 148 0.010
Fly
response to fatty acid GO:0070542 65 0.010
peptide transport GO:0015833 97 0.010
cellular response to electrical stimulus GO:0071257 8 0.010
hormone secretion GO:0046879 115 0.010
brain development GO:0007420 247 0.010
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.010
multicellular organism reproduction GO:0032504 233 0.010
Fly
fatty acid metabolic process GO:0006631 99 0.010
response to ionizing radiation GO:0010212 59 0.010
regulation of secretion by cell GO:1903530 208 0.010
cellular response to corticosteroid stimulus GO:0071384 69 0.010
response to lipopolysaccharide GO:0032496 191 0.010
cytoplasmic transport GO:0016482 115 0.010

Tpm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 0 0.206
disease of anatomical entity DOID:7 0 0.206
Human
vascular disease DOID:178 0 0.028
artery disease DOID:0050828 0 0.028
nervous system disease DOID:863 0 0.022
sensory system disease DOID:0050155 0 0.022
eye disease DOID:5614 0 0.017
eye and adnexa disease DOID:1492 0 0.017
musculoskeletal system disease DOID:17 0 0.011
Human