Rattus norvegicus

12 known processes

Treh

trehalase (brush-border membrane glycoprotein)

Treh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid transport GO:0015718 52 0.418
transmembrane transport GO:0055085 412 0.340
organic anion transport GO:0015711 132 0.318
anion transport GO:0006820 178 0.287
organic acid transport GO:0015849 116 0.280
amino acid transport GO:0006865 70 0.250
carboxylic acid transport GO:0046942 115 0.221
brain development GO:0007420 247 0.216
positive regulation of transcription dna templated GO:0045893 197 0.188
regulation of phosphorylation GO:0042325 248 0.167
aging GO:0007568 241 0.156
central nervous system development GO:0007417 311 0.155
anion transmembrane transport GO:0098656 77 0.144
response to external biotic stimulus GO:0043207 221 0.143
organophosphate metabolic process GO:0019637 370 0.140
cation transport GO:0006812 382 0.135
ion transmembrane transport GO:0034220 365 0.133
organelle organization GO:0006996 266 0.131
neuron differentiation GO:0030182 368 0.127
head development GO:0060322 247 0.125
response to acid chemical GO:0001101 222 0.124
cellular chemical homeostasis GO:0055082 247 0.118
reproductive process GO:0022414 372 0.116
response to lipopolysaccharide GO:0032496 191 0.114
response to estrogen GO:0043627 232 0.114
response to nutrient levels GO:0031667 370 0.105
organophosphate biosynthetic process GO:0090407 143 0.104
regulation of molecular function GO:0065009 398 0.104
organic acid metabolic process GO:0006082 292 0.101
regulation of cell proliferation GO:0042127 359 0.100
response to wounding GO:0009611 254 0.099
oxoacid metabolic process GO:0043436 290 0.095
regulation of multicellular organismal development GO:2000026 376 0.087
response to estradiol GO:0032355 164 0.086
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.086
positive regulation of phosphorus metabolic process GO:0010562 262 0.085
regulation of cell projection organization GO:0031344 175 0.084
protein complex biogenesis GO:0070271 263 0.084
regulation of neuron differentiation GO:0045664 208 0.080
carbohydrate derivative metabolic process GO:1901135 346 0.080
positive regulation of gene expression GO:0010628 244 0.079
negative regulation of neurogenesis GO:0050768 78 0.079
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.077
locomotion GO:0040011 237 0.076
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.076
response to biotic stimulus GO:0009607 226 0.072
positive regulation of multicellular organismal process GO:0051240 387 0.071
regulation of phosphate metabolic process GO:0019220 349 0.070
positive regulation of cellular component organization GO:0051130 200 0.069
macromolecular complex subunit organization GO:0043933 339 0.068
response to oxygen levels GO:0070482 265 0.067
response to extracellular stimulus GO:0009991 380 0.067
regulation of neurogenesis GO:0050767 247 0.066
regulation of cell differentiation GO:0045595 320 0.064
organic hydroxy compound metabolic process GO:1901615 115 0.064
amide transport GO:0042886 105 0.062
programmed cell death GO:0012501 392 0.062
regulation of apoptotic process GO:0042981 335 0.062
cell projection organization GO:0030030 302 0.062
transcription from rna polymerase ii promoter GO:0006366 252 0.061
protein homooligomerization GO:0051260 91 0.061
positive regulation of nucleic acid templated transcription GO:1903508 197 0.060
positive regulation of response to stimulus GO:0048584 285 0.058
positive regulation of rna metabolic process GO:0051254 203 0.057
regulation of transcription dna templated GO:0006355 374 0.057
positive regulation of cellular biosynthetic process GO:0031328 295 0.057
regulation of rna metabolic process GO:0051252 391 0.056
macromolecule localization GO:0033036 252 0.056
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.055
nucleic acid templated transcription GO:0097659 379 0.055
synaptic transmission GO:0007268 235 0.054
proteolysis GO:0006508 175 0.054
response to glucocorticoid GO:0051384 223 0.054
carbohydrate derivative biosynthetic process GO:1901137 124 0.054
response to cytokine GO:0034097 215 0.053
neuron development GO:0048666 286 0.052
nitrogen compound transport GO:0071705 229 0.051
nucleoside phosphate biosynthetic process GO:1901293 102 0.049
response to retinoic acid GO:0032526 63 0.049
response to nutrient GO:0007584 248 0.048
response to hexose GO:0009746 144 0.047
immune system process GO:0002376 204 0.047
positive regulation of cell death GO:0010942 184 0.047
response to starvation GO:0042594 59 0.047
response to bacterium GO:0009617 200 0.047
cellular response to lipopolysaccharide GO:0071222 55 0.046
tissue development GO:0009888 252 0.046
multicellular organism reproduction GO:0032504 233 0.046
response to glucose GO:0009749 136 0.046
ribose phosphate biosynthetic process GO:0046390 87 0.046
chemical homeostasis GO:0048878 292 0.046
positive regulation of phosphorylation GO:0042327 177 0.045
regulation of nervous system development GO:0051960 264 0.045
positive regulation of neuron differentiation GO:0045666 126 0.045
bile acid and bile salt transport GO:0015721 12 0.045
positive regulation of biosynthetic process GO:0009891 319 0.043
cellular component assembly GO:0022607 360 0.043
regulation of cellular component organization GO:0051128 368 0.043
positive regulation of cell proliferation GO:0008284 249 0.043
positive regulation of neurogenesis GO:0050769 165 0.043
macromolecular complex assembly GO:0065003 273 0.042
response to monosaccharide GO:0034284 159 0.041
regulation of ion transport GO:0043269 245 0.040
inflammatory response GO:0006954 150 0.040
positive regulation of phosphate metabolic process GO:0045937 262 0.040
tongue morphogenesis GO:0043587 3 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.040
response to food GO:0032094 27 0.039
forebrain development GO:0030900 98 0.039
cellular response to endogenous stimulus GO:0071495 377 0.039
rna metabolic process GO:0016070 406 0.038
protein oligomerization GO:0051259 191 0.038
homeostatic process GO:0042592 331 0.038
multi organism reproductive process GO:0044703 262 0.038
regulation of neuron projection development GO:0010975 161 0.038
negative regulation of cell death GO:0060548 229 0.037
sexual reproduction GO:0019953 148 0.037
eosinophil migration GO:0072677 3 0.036
cellular component movement GO:0006928 248 0.036
negative regulation of programmed cell death GO:0043069 183 0.036
positive regulation of developmental process GO:0051094 283 0.035
protein complex assembly GO:0006461 263 0.035
positive regulation of molecular function GO:0044093 230 0.035
regulation of cell development GO:0060284 263 0.033
oligopeptide transport GO:0006857 4 0.033
modified amino acid transport GO:0072337 12 0.033
cell projection morphogenesis GO:0048858 123 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.033
positive regulation of programmed cell death GO:0043068 157 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
carboxylic acid metabolic process GO:0019752 289 0.033
divalent inorganic cation transport GO:0072511 134 0.032
negative regulation of chronic inflammatory response GO:0002677 2 0.032
cell cell signaling GO:0007267 335 0.032
single organism reproductive process GO:0044702 297 0.032
neuron projection development GO:0031175 273 0.031
cellular component biogenesis GO:0044085 368 0.031
nucleotide biosynthetic process GO:0009165 98 0.031
positive regulation of nervous system development GO:0051962 178 0.031
single organism organelle organization GO:1902589 180 0.031
ribonucleotide metabolic process GO:0009259 231 0.030
response to molecule of bacterial origin GO:0002237 194 0.030
regulation of programmed cell death GO:0043067 341 0.030
response to carbohydrate GO:0009743 183 0.030
nucleotide metabolic process GO:0009117 279 0.030
cellular homeostasis GO:0019725 252 0.030
epithelial cell differentiation GO:0030855 71 0.029
response to toxic substance GO:0009636 133 0.029
positive regulation of cell projection organization GO:0031346 111 0.029
positive regulation of homeostatic process GO:0032846 49 0.029
striated muscle contraction GO:0006941 44 0.029
amine metabolic process GO:0009308 38 0.029
calcium ion homeostasis GO:0055074 162 0.029
negative regulation of apoptotic process GO:0043066 181 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
anterior posterior pattern specification GO:0009952 1 0.028
defense response GO:0006952 194 0.028
reproduction GO:0000003 245 0.027
neuron neuron synaptic transmission GO:0007270 60 0.027
response to other organism GO:0051707 220 0.027
metal ion transport GO:0030001 289 0.027
regulation of dendrite development GO:0050773 59 0.027
divalent metal ion transport GO:0070838 132 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
taxis GO:0042330 67 0.026
single organism cellular localization GO:1902580 102 0.026
carbohydrate metabolic process GO:0005975 130 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
rna biosynthetic process GO:0032774 380 0.026
response to histamine GO:0034776 3 0.025
protein phosphorylation GO:0006468 345 0.025
cerebellar granule cell precursor proliferation GO:0021930 1 0.025
neuron projection morphogenesis GO:0048812 122 0.025
cellular amine metabolic process GO:0044106 38 0.025
cellular response to cytokine stimulus GO:0071345 127 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
developmental process involved in reproduction GO:0003006 159 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
muscle system process GO:0003012 115 0.024
protein complex subunit organization GO:0071822 302 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
negative regulation of neuron differentiation GO:0045665 62 0.024
transcription dna templated GO:0006351 377 0.024
regulation of erk1 and erk2 cascade GO:0070372 41 0.024
cytokine production GO:0001816 61 0.023
cellular response to external stimulus GO:0071496 118 0.023
negative regulation of cell differentiation GO:0045596 99 0.023
cellular response to stress GO:0033554 269 0.023
response to decreased oxygen levels GO:0036293 237 0.022
positive regulation of transport GO:0051050 245 0.022
smooth muscle cell proliferation GO:0048659 77 0.022
limbic system development GO:0021761 38 0.022
regulation of membrane potential GO:0042391 110 0.022
intracellular signal transduction GO:0035556 314 0.022
signal transduction by phosphorylation GO:0023014 144 0.022
regulation of transmembrane transport GO:0034762 122 0.022
response to radiation GO:0009314 137 0.021
regulation of homeostatic process GO:0032844 101 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
endocytosis GO:0006897 84 0.021
regulation of cellular component movement GO:0051270 150 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.021
actin filament based process GO:0030029 86 0.021
purine ribonucleotide biosynthetic process GO:0009152 81 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
negative regulation of transport GO:0051051 136 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
positive regulation of mapk cascade GO:0043410 92 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.019
vitamin transport GO:0051180 14 0.019
neurological system process GO:0050877 219 0.019
response to cocaine GO:0042220 39 0.019
heart process GO:0003015 57 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
cellular cation homeostasis GO:0030003 180 0.019
one carbon compound transport GO:0019755 5 0.019
regulation of organelle organization GO:0033043 80 0.019
male gamete generation GO:0048232 99 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
organelle localization GO:0051640 55 0.019
regulation of leukocyte activation GO:0002694 45 0.018
regulation of peptide secretion GO:0002791 82 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
positive regulation of signal transduction GO:0009967 175 0.018
cellular lipid metabolic process GO:0044255 208 0.018
negative regulation of molecular function GO:0044092 133 0.018
dendrite morphogenesis GO:0048813 43 0.018
response to purine containing compound GO:0014074 126 0.018
spermatogenesis GO:0007283 99 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
cellular ion homeostasis GO:0006873 184 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
synapse assembly GO:0007416 29 0.018
cellular macromolecule localization GO:0070727 122 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
peptide transport GO:0015833 97 0.018
choline transport GO:0015871 4 0.018
regulation of cytokine production GO:0001817 56 0.018
regulation of ion transmembrane transport GO:0034765 121 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
secretion GO:0046903 307 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.017
regulation of cation channel activity GO:2001257 23 0.017
positive regulation of secretion GO:0051047 140 0.017
regulation of signal transduction GO:0009966 318 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
drug transmembrane transport GO:0006855 13 0.017
response to axon injury GO:0048678 59 0.017
regulation of peptide transport GO:0090087 87 0.017
lipid localization GO:0010876 62 0.017
establishment of organelle localization GO:0051656 37 0.017
ribonucleotide biosynthetic process GO:0009260 85 0.016
calcium ion transport GO:0006816 131 0.016
gamete generation GO:0007276 124 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
sequestering of metal ion GO:0051238 9 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
protein maturation GO:0051604 68 0.016
acid secretion GO:0046717 48 0.016
somatostatin receptor signaling pathway GO:0038169 4 0.016
eosinophil chemotaxis GO:0048245 3 0.016
cellular catabolic process GO:0044248 295 0.016
purine nucleotide biosynthetic process GO:0006164 83 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
positive regulation of locomotion GO:0040017 102 0.016
pancreatic stellate cell proliferation GO:0072343 2 0.015
response to growth factor GO:0070848 189 0.015
cellular response to nutrient levels GO:0031669 60 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
synaptic transmission gabaergic GO:0051932 22 0.015
regulation of protein metabolic process GO:0051246 289 0.015
alcohol metabolic process GO:0006066 77 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
response to ammonium ion GO:0060359 71 0.015
cellular response to molecule of bacterial origin GO:0071219 56 0.015
organic substance catabolic process GO:1901575 316 0.015
cellular response to abiotic stimulus GO:0071214 85 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.015
cellular component morphogenesis GO:0032989 155 0.015
response to camp GO:0051591 91 0.015
ion homeostasis GO:0050801 212 0.015
wound healing GO:0042060 122 0.015
peptide hormone secretion GO:0030072 84 0.014
response to metal ion GO:0010038 253 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
sensory organ development GO:0007423 74 0.014
dephosphorylation GO:0016311 98 0.014
negative regulation of nervous system development GO:0051961 79 0.014
muscle contraction GO:0006936 88 0.014
regulation of blood pressure GO:0008217 83 0.014
purine containing compound metabolic process GO:0072521 253 0.014
olfactory behavior GO:0042048 2 0.014
camp biosynthetic process GO:0006171 47 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
cardiac muscle contraction GO:0060048 27 0.014
response to mechanical stimulus GO:0009612 134 0.014
lipid transport GO:0006869 61 0.014
protein localization GO:0008104 191 0.013
positive regulation of ion transport GO:0043270 94 0.013
regulation of peptide hormone secretion GO:0090276 80 0.013
cell part morphogenesis GO:0032990 123 0.013
multi multicellular organism process GO:0044706 138 0.013
organic hydroxy compound transport GO:0015850 77 0.013
cyclic purine nucleotide metabolic process GO:0052652 62 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
sequestering of calcium ion GO:0051208 8 0.013
sex differentiation GO:0007548 113 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
apoptotic process GO:0006915 381 0.013
mesoderm development GO:0007498 2 0.013
cyclic nucleotide biosynthetic process GO:0009190 63 0.013
positive regulation of cell development GO:0010720 176 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
negative regulation of metabolic process GO:0009892 331 0.013
response to corticosteroid GO:0031960 235 0.013
antibiotic transport GO:0042891 2 0.013
circulatory system process GO:0003013 183 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
memory GO:0007613 54 0.013
response to vitamin GO:0033273 131 0.013
dendrite development GO:0016358 72 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
inflammatory response to antigenic stimulus GO:0002437 18 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
cation transmembrane transport GO:0098655 263 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
behavior GO:0007610 205 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
formation of primary germ layer GO:0001704 1 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
regulation of anatomical structure size GO:0090066 135 0.012
bile acid secretion GO:0032782 5 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.012
vesicle organization GO:0016050 29 0.012
embryonic pattern specification GO:0009880 1 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
response to hypoxia GO:0001666 231 0.012
negative regulation of blood pressure GO:0045776 29 0.012
receptor mediated endocytosis GO:0006898 42 0.012
cellular ketone metabolic process GO:0042180 51 0.012
phospholipid metabolic process GO:0006644 61 0.012
regulation of metal ion transport GO:0010959 118 0.012
complement receptor mediated signaling pathway GO:0002430 2 0.012
regulation of muscle system process GO:0090257 79 0.012
negative regulation of signaling GO:0023057 157 0.011
inorganic anion transport GO:0015698 41 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
blood circulation GO:0008015 183 0.011
cellular response to ammonium ion GO:0071242 17 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
regulation of response to stress GO:0080134 126 0.011
regulation of embryonic development GO:0045995 2 0.011
regulation of chronic inflammatory response GO:0002676 3 0.011
response to ketone GO:1901654 182 0.011
establishment of protein localization GO:0045184 141 0.011
glycerol transport GO:0015793 2 0.011
negative regulation of developmental process GO:0051093 125 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regulation of dendrite morphogenesis GO:0048814 33 0.011
organ formation GO:0048645 3 0.011
cell migration GO:0016477 197 0.011
gliogenesis GO:0042063 93 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
multicellular organism growth GO:0035264 1 0.011
nucleoside metabolic process GO:0009116 179 0.010
positive regulation of dendritic spine development GO:0060999 9 0.010
response to amphetamine GO:0001975 25 0.010
sulfur compound transport GO:0072348 8 0.010
blood vessel development GO:0001568 69 0.010
actin cytoskeleton organization GO:0030036 73 0.010
regulation of response to external stimulus GO:0032101 106 0.010
regulation of transporter activity GO:0032409 50 0.010
regulation of secretion GO:0051046 224 0.010
regulation of calcium ion transport GO:0051924 77 0.010
glucose homeostasis GO:0042593 75 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.010
embryonic axis specification GO:0000578 1 0.010
regulation of tube size GO:0035150 89 0.010
regulation of t cell activation GO:0050863 23 0.010
vesicle localization GO:0051648 33 0.010
regulation of cellular localization GO:0060341 263 0.010
signal release GO:0023061 145 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010

Treh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.024
muscular disease DOID:0080000 0 0.024
muscle tissue disease DOID:66 0 0.018
myopathy DOID:423 0 0.018
nervous system disease DOID:863 0 0.018
endocrine system disease DOID:28 0 0.011
disease of metabolism DOID:0014667 0 0.010