Rattus norvegicus

214 known processes

Tsc2

tuberous sclerosis 2

(Aliases: Rc)

Tsc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of molecular function GO:0065009 398 0.411
organophosphate metabolic process GO:0019637 370 0.287
cellular component assembly GO:0022607 360 0.251
macromolecular complex subunit organization GO:0043933 339 0.217
cellular component biogenesis GO:0044085 368 0.200
reproductive process GO:0022414 372 0.184
Fly
oxoacid metabolic process GO:0043436 290 0.177
organelle organization GO:0006996 266 0.164
protein complex biogenesis GO:0070271 263 0.164
regulation of phosphate metabolic process GO:0019220 349 0.162
programmed cell death GO:0012501 392 0.140
macromolecule localization GO:0033036 252 0.139
vesicle mediated transport GO:0016192 181 0.138
Mouse Fly
protein complex subunit organization GO:0071822 302 0.136
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.135
regulation of cellular localization GO:0060341 263 0.133
positive regulation of phosphorus metabolic process GO:0010562 262 0.119
positive regulation of molecular function GO:0044093 230 0.112
response to inorganic substance GO:0010035 377 0.111
neuron differentiation GO:0030182 368 0.110
anatomical structure morphogenesis GO:0009653 298 0.109
Mouse Fly
single organism reproductive process GO:0044702 297 0.108
Fly
protein complex assembly GO:0006461 263 0.107
cellular macromolecule localization GO:0070727 122 0.107
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.105
Mouse
nucleic acid templated transcription GO:0097659 379 0.101
Mouse
reproduction GO:0000003 245 0.097
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.094
rna biosynthetic process GO:0032774 380 0.093
Mouse
rna metabolic process GO:0016070 406 0.089
Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.089
Mouse
negative regulation of response to stimulus GO:0048585 155 0.088
cellular lipid metabolic process GO:0044255 208 0.087
single organism intracellular transport GO:1902582 166 0.087
Mouse
intracellular protein transport GO:0006886 79 0.086
Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.084
Fly
cellular catabolic process GO:0044248 295 0.082
multicellular organism reproduction GO:0032504 233 0.079
Fly
developmental growth GO:0048589 100 0.078
Fly
immune system process GO:0002376 204 0.077
amide biosynthetic process GO:0043604 10 0.077
response to extracellular stimulus GO:0009991 380 0.076
Fly
macromolecular complex assembly GO:0065003 273 0.076
glycerolipid metabolic process GO:0046486 67 0.075
response to metal ion GO:0010038 253 0.074
catabolic process GO:0009056 351 0.073
positive regulation of phosphate metabolic process GO:0045937 262 0.070
regulation of protein phosphorylation GO:0001932 183 0.070
cellular component movement GO:0006928 248 0.069
regulation of nervous system development GO:0051960 264 0.068
Fly
protein phosphorylation GO:0006468 345 0.067
single organism organelle organization GO:1902589 180 0.067
regulation of protein modification process GO:0031399 194 0.065
ribonucleotide catabolic process GO:0009261 136 0.064
regulation of cellular component biogenesis GO:0044087 86 0.064
Fly
regulation of growth GO:0040008 105 0.063
Fly
developmental process involved in reproduction GO:0003006 159 0.062
Fly
behavior GO:0007610 205 0.062
regulation of apoptotic process GO:0042981 335 0.062
transmembrane transport GO:0055085 412 0.061
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.061
Fly
regulation of cell differentiation GO:0045595 320 0.061
regulation of cellular protein metabolic process GO:0032268 267 0.060
intracellular signal transduction GO:0035556 314 0.060
growth GO:0040007 165 0.060
Fly
carboxylic acid metabolic process GO:0019752 289 0.058
positive regulation of nervous system development GO:0051962 178 0.058
purine containing compound catabolic process GO:0072523 138 0.057
regulation of catalytic activity GO:0050790 304 0.056
limb morphogenesis GO:0035108 4 0.056
organic substance catabolic process GO:1901575 316 0.055
secretion GO:0046903 307 0.055
organic hydroxy compound metabolic process GO:1901615 115 0.055
regulation of phosphorus metabolic process GO:0051174 349 0.055
anion transport GO:0006820 178 0.054
positive regulation of multicellular organismal process GO:0051240 387 0.053
regulation of signal transduction GO:0009966 318 0.052
organic acid metabolic process GO:0006082 292 0.051
regulation of transmembrane transporter activity GO:0022898 49 0.050
apoptotic process GO:0006915 381 0.049
cellular protein complex assembly GO:0043623 44 0.049
regulation of transporter activity GO:0032409 50 0.049
gamete generation GO:0007276 124 0.049
Fly
nitrogen compound transport GO:0071705 229 0.048
regulation of catabolic process GO:0009894 113 0.048
purine nucleotide metabolic process GO:0006163 229 0.048
positive regulation of transport GO:0051050 245 0.048
regulation of transcription dna templated GO:0006355 374 0.048
Mouse
negative regulation of cell differentiation GO:0045596 99 0.048
nucleotide metabolic process GO:0009117 279 0.047
nucleobase containing small molecule metabolic process GO:0055086 316 0.046
response to external biotic stimulus GO:0043207 221 0.046
neuron neuron synaptic transmission GO:0007270 60 0.046
cellular response to hormone stimulus GO:0032870 247 0.046
Mouse Fly
chemical homeostasis GO:0048878 292 0.046
positive regulation of cellular component organization GO:0051130 200 0.046
positive regulation of secretion GO:0051047 140 0.045
cytoskeleton organization GO:0007010 111 0.045
cell motility GO:0048870 202 0.045
central nervous system development GO:0007417 311 0.044
purine ribonucleotide catabolic process GO:0009154 136 0.043
learning or memory GO:0007611 90 0.042
intracellular transport GO:0046907 185 0.042
Mouse
negative regulation of cell communication GO:0010648 158 0.042
multi organism reproductive process GO:0044703 262 0.042
Fly
protein localization GO:0008104 191 0.042
establishment of vesicle localization GO:0051650 31 0.041
regulation of system process GO:0044057 208 0.041
cell migration GO:0016477 197 0.041
nucleoside triphosphate catabolic process GO:0009143 123 0.040
response to nutrient levels GO:0031667 370 0.040
Fly
regulation of rna biosynthetic process GO:2001141 381 0.040
Mouse
brain development GO:0007420 247 0.040
response to acid chemical GO:0001101 222 0.040
immune response GO:0006955 104 0.040
nucleoside phosphate catabolic process GO:1901292 140 0.040
cellular amino acid metabolic process GO:0006520 107 0.039
regulation of transmembrane transport GO:0034762 122 0.039
neuron projection development GO:0031175 273 0.039
positive regulation of rna metabolic process GO:0051254 203 0.039
Mouse
multicellular organismal reproductive process GO:0048609 233 0.039
Fly
ion transmembrane transport GO:0034220 365 0.039
regulation of response to external stimulus GO:0032101 106 0.039
gliogenesis GO:0042063 93 0.038
taxis GO:0042330 67 0.038
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.037
locomotion GO:0040011 237 0.037
Mouse
regulation of multicellular organismal development GO:2000026 376 0.037
Fly
sexual reproduction GO:0019953 148 0.037
Fly
regulation of cellular catabolic process GO:0031329 101 0.036
protein autophosphorylation GO:0046777 66 0.036
mitotic spindle organization GO:0007052 2 0.036
g protein coupled receptor signaling pathway GO:0007186 242 0.036
ribonucleotide metabolic process GO:0009259 231 0.036
positive regulation of biosynthetic process GO:0009891 319 0.035
Mouse
synaptic transmission GO:0007268 235 0.035
Fly
lipid metabolic process GO:0006629 283 0.035
Fly
negative regulation of nervous system development GO:0051961 79 0.034
Fly
single organism catabolic process GO:0044712 283 0.034
neuron development GO:0048666 286 0.034
regulation of purine nucleotide catabolic process GO:0033121 65 0.034
localization of cell GO:0051674 202 0.034
organic cyclic compound catabolic process GO:1901361 175 0.033
nucleoside triphosphate metabolic process GO:0009141 144 0.033
regulation of gtpase activity GO:0043087 57 0.033
regulation of phosphorylation GO:0042325 248 0.033
peptide biosynthetic process GO:0043043 3 0.033
transcription dna templated GO:0006351 377 0.033
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 141 0.032
protein transport GO:0015031 132 0.032
Mouse
amine metabolic process GO:0009308 38 0.032
axis specification GO:0009798 4 0.032
response to ketone GO:1901654 182 0.032
ribose phosphate metabolic process GO:0019693 235 0.032
negative regulation of molecular function GO:0044092 133 0.032
homeostatic process GO:0042592 331 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
Mouse
nucleoside metabolic process GO:0009116 179 0.031
cellular response to endogenous stimulus GO:0071495 377 0.031
Mouse Fly
multi multicellular organism process GO:0044706 138 0.031
positive regulation of protein phosphorylation GO:0001934 135 0.031
Fly
neuron projection morphogenesis GO:0048812 122 0.031
response to wounding GO:0009611 254 0.030
purine ribonucleoside catabolic process GO:0046130 124 0.030
cell projection organization GO:0030030 302 0.030
regulation of nucleotide metabolic process GO:0006140 117 0.030
regulation of amine transport GO:0051952 54 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.030
Mouse
cellular protein localization GO:0034613 122 0.030
Mouse
biological adhesion GO:0022610 110 0.029
purine nucleoside metabolic process GO:0042278 169 0.029
regulation of anatomical structure size GO:0090066 135 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
purine containing compound metabolic process GO:0072521 253 0.029
positive regulation of protein metabolic process GO:0051247 178 0.029
Fly
negative regulation of neurogenesis GO:0050768 78 0.028
spindle organization GO:0007051 2 0.028
secretion by cell GO:0032940 248 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
Mouse
positive regulation of transcription dna templated GO:0045893 197 0.028
Mouse
appendage morphogenesis GO:0035107 4 0.027
purine ribonucleoside metabolic process GO:0046128 168 0.027
heterocycle catabolic process GO:0046700 167 0.027
microtubule organizing center organization GO:0031023 1 0.027
enzyme linked receptor protein signaling pathway GO:0007167 116 0.027
Mouse Fly
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.027
phospholipid metabolic process GO:0006644 61 0.027
eye morphogenesis GO:0048592 4 0.027
regulation of proteasomal protein catabolic process GO:0061136 4 0.027
cellular homeostasis GO:0019725 252 0.027
glycosyl compound catabolic process GO:1901658 126 0.027
response to estradiol GO:0032355 164 0.027
cellular amide metabolic process GO:0043603 44 0.026
regulation of cellular component organization GO:0051128 368 0.026
Mouse Fly
positive regulation of cell death GO:0010942 184 0.026
actin cytoskeleton organization GO:0030036 73 0.026
cellular chemical homeostasis GO:0055082 247 0.026
cellular amine metabolic process GO:0044106 38 0.026
negative regulation of metabolic process GO:0009892 331 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
nucleotide catabolic process GO:0009166 139 0.026
neurological system process GO:0050877 219 0.026
regulation of neurogenesis GO:0050767 247 0.026
cardiovascular system development GO:0072358 134 0.026
Mouse
purine ribonucleotide metabolic process GO:0009150 227 0.026
regulation of secretion by cell GO:1903530 208 0.025
response to other organism GO:0051707 220 0.025
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.025
cellular ketone metabolic process GO:0042180 51 0.025
negative regulation of signal transduction GO:0009968 83 0.025
vesicle localization GO:0051648 33 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
response to peptide GO:1901652 292 0.024
Mouse Fly
negative regulation of rna biosynthetic process GO:1902679 118 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.024
cellular response to stress GO:0033554 269 0.024
Fly
purine nucleoside catabolic process GO:0006152 124 0.024
negative regulation of transport GO:0051051 136 0.024
synaptic vesicle transport GO:0048489 23 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
Fly
positive regulation of cell projection organization GO:0031346 111 0.023
cellular macromolecular complex assembly GO:0034622 58 0.023
single organism biosynthetic process GO:0044711 342 0.023
response to organophosphorus GO:0046683 102 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
Mouse Fly
establishment of protein localization GO:0045184 141 0.023
regulation of cell development GO:0060284 263 0.023
negative regulation of cell death GO:0060548 229 0.023
tissue development GO:0009888 252 0.022
Mouse Fly
response to carbohydrate GO:0009743 183 0.022
heart development GO:0007507 72 0.022
Mouse
positive regulation of neuron differentiation GO:0045666 126 0.022
cognition GO:0050890 92 0.022
regulation of programmed cell death GO:0043067 341 0.022
regulation of nucleoside metabolic process GO:0009118 66 0.022
synaptic vesicle endocytosis GO:0048488 4 0.021
negative regulation of cell development GO:0010721 82 0.021
cell adhesion GO:0007155 110 0.021
positive regulation of signaling GO:0023056 270 0.021
positive regulation of catabolic process GO:0009896 78 0.021
response to estrogen GO:0043627 232 0.021
regulation of neuron differentiation GO:0045664 208 0.021
organic hydroxy compound transport GO:0015850 77 0.021
cell projection morphogenesis GO:0048858 123 0.021
regulation of synapse assembly GO:0051963 15 0.021
Fly
inorganic ion transmembrane transport GO:0098660 229 0.021
response to monosaccharide GO:0034284 159 0.021
muscle system process GO:0003012 115 0.021
cellular component morphogenesis GO:0032989 155 0.021
carbohydrate metabolic process GO:0005975 130 0.021
peptide metabolic process GO:0006518 32 0.021
inorganic cation transmembrane transport GO:0098662 202 0.021
anterior posterior pattern specification GO:0009952 1 0.020
immune effector process GO:0002252 53 0.020
positive regulation of cell development GO:0010720 176 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
regulation of nucleotide catabolic process GO:0030811 65 0.020
memory GO:0007613 54 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
Mouse
cell growth GO:0016049 104 0.020
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.020
chromosome organization GO:0051276 36 0.020
positive regulation of developmental process GO:0051094 283 0.020
nucleoside catabolic process GO:0009164 126 0.020
forebrain development GO:0030900 98 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
Mouse
negative regulation of phosphate metabolic process GO:0045936 80 0.020
negative regulation of biosynthetic process GO:0009890 168 0.019
positive regulation of hydrolase activity GO:0051345 86 0.019
response to growth factor GO:0070848 189 0.019
maintenance of location GO:0051235 17 0.019
regulation of ion transmembrane transport GO:0034765 121 0.019
synaptic vesicle localization GO:0097479 24 0.019
positive regulation of neuron projection development GO:0010976 99 0.019
ribonucleoside catabolic process GO:0042454 126 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
negative regulation of innate immune response GO:0045824 4 0.019
circulatory system development GO:0072359 134 0.019
Mouse
regulation of cell growth GO:0001558 85 0.019
Fly
positive regulation of gene expression GO:0010628 244 0.019
Mouse
embryonic limb morphogenesis GO:0030326 4 0.019
rhythmic process GO:0048511 156 0.019
regulation of calcium ion transmembrane transport GO:1903169 18 0.019
dna metabolic process GO:0006259 96 0.019
cell cell signaling GO:0007267 335 0.019
Fly
cell cycle GO:0007049 101 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
regulation of immune response GO:0050776 55 0.019
cell morphogenesis involved in differentiation GO:0000904 119 0.019
regulation of neuron projection development GO:0010975 161 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
positive regulation of transferase activity GO:0051347 81 0.018
small molecule biosynthetic process GO:0044283 124 0.018
blood circulation GO:0008015 183 0.018
positive regulation of protein modification process GO:0031401 142 0.018
Fly
calcium ion transmembrane transport GO:0070588 70 0.018
cytoplasmic transport GO:0016482 115 0.018
Mouse
protein localization to organelle GO:0033365 57 0.018
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.018
regulation of immune system process GO:0002682 123 0.018
gastrulation GO:0007369 2 0.018
cell fate determination GO:0001709 2 0.017
epithelium development GO:0060429 96 0.017
Mouse
cytosolic calcium ion homeostasis GO:0051480 140 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
Mouse Fly
regulation of homeostatic process GO:0032844 101 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
insulin like growth factor receptor signaling pathway GO:0048009 3 0.017
Mouse
positive regulation of ion transport GO:0043270 94 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
centrosome organization GO:0051297 1 0.017
glial cell differentiation GO:0010001 65 0.017
signal release GO:0023061 145 0.017
gtp metabolic process GO:0046039 72 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
cation transport GO:0006812 382 0.017
monocarboxylic acid transport GO:0015718 52 0.017
neuromuscular synaptic transmission GO:0007274 2 0.016
regulation of blood vessel size GO:0050880 89 0.016
regulation of body fluid levels GO:0050878 90 0.016
negative regulation of developmental process GO:0051093 125 0.016
Fly
single organism cellular localization GO:1902580 102 0.016
Mouse
lipid transport GO:0006869 61 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of blood circulation GO:1903522 110 0.016
actin filament based process GO:0030029 86 0.016
response to purine containing compound GO:0014074 126 0.016
guanosine containing compound catabolic process GO:1901069 71 0.016
embryonic appendage morphogenesis GO:0035113 4 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
positive regulation of cellular catabolic process GO:0031331 71 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
response to biotic stimulus GO:0009607 226 0.016
female pregnancy GO:0007565 122 0.015
response to oxygen levels GO:0070482 265 0.015
Mouse Fly
heart contraction GO:0060047 57 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
regulation of rna metabolic process GO:0051252 391 0.015
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
glycerophospholipid metabolic process GO:0006650 47 0.015
heart morphogenesis GO:0003007 3 0.015
wound healing GO:0042060 122 0.015
protein localization to chromosome centromeric region GO:0071459 1 0.015
response to oxidative stress GO:0006979 186 0.015
regulation of protein localization GO:0032880 81 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
positive regulation of locomotion GO:0040017 102 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
aging GO:0007568 241 0.015
Fly
blood vessel morphogenesis GO:0048514 58 0.015
head development GO:0060322 247 0.015
rna localization GO:0006403 4 0.015
axonogenesis GO:0007409 71 0.015
response to amino acid GO:0043200 75 0.015
organic acid transport GO:0015849 116 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
response to hexose GO:0009746 144 0.014
synaptic transmission glutamatergic GO:0035249 33 0.014
response to insulin GO:0032868 133 0.014
Mouse Fly
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.014
regulation of axonogenesis GO:0050770 37 0.014
male gamete generation GO:0048232 99 0.014
regulation of anion transport GO:0044070 43 0.014
circulatory system process GO:0003013 183 0.014
chromatin assembly or disassembly GO:0006333 1 0.014
regulation of cell projection organization GO:0031344 175 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
cardiac chamber development GO:0003205 1 0.014
response to vitamin GO:0033273 131 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
spermatogenesis GO:0007283 99 0.014
response to ethanol GO:0045471 162 0.014
metal ion transport GO:0030001 289 0.014
regulation of secretion GO:0051046 224 0.014
regulation of dna metabolic process GO:0051052 60 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
alcohol metabolic process GO:0006066 77 0.014
single organism behavior GO:0044708 130 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
multicellular organism growth GO:0035264 1 0.014
endocytosis GO:0006897 84 0.013
Mouse Fly
gland development GO:0048732 155 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
olfactory behavior GO:0042048 2 0.013
positive regulation of gtp catabolic process GO:0033126 48 0.013
ras protein signal transduction GO:0007265 29 0.013
regulation of cell cycle GO:0051726 73 0.013
negative regulation of phosphorylation GO:0042326 57 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
Fly
regulation of transferase activity GO:0051338 123 0.013
establishment of organelle localization GO:0051656 37 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
positive regulation of nucleoside metabolic process GO:0045979 55 0.013
dendrite development GO:0016358 72 0.013
positive regulation of cellular component biogenesis GO:0044089 55 0.013
vascular process in circulatory system GO:0003018 96 0.013
regulation of defense response GO:0031347 68 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
Mouse
cellular response to glucose stimulus GO:0071333 65 0.013
regulation of cell adhesion GO:0030155 52 0.013
response to hydrogen peroxide GO:0042542 89 0.013
regulation of synaptic transmission GO:0050804 141 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
positive regulation of amine transport GO:0051954 26 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
regulation of developmental growth GO:0048638 45 0.012
Fly
oxidation reduction process GO:0055114 304 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
axon cargo transport GO:0008088 1 0.012
artery development GO:0060840 3 0.012
response to peptide hormone GO:0043434 278 0.012
Mouse Fly
regulation of cation channel activity GO:2001257 23 0.012
regulation of calcium ion transmembrane transporter activity GO:1901019 17 0.012
regulation of ion transport GO:0043269 245 0.012
learning GO:0007612 33 0.012
amine transport GO:0015837 57 0.012
carbohydrate homeostasis GO:0033500 75 0.012
cation homeostasis GO:0055080 195 0.012
regulation of cell migration GO:0030334 128 0.012
response to toxic substance GO:0009636 133 0.012
regulation of neuron death GO:1901214 115 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
lipid localization GO:0010876 62 0.012
double strand break repair GO:0006302 1 0.012
divalent inorganic cation transport GO:0072511 134 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
Fly
nucleic acid transport GO:0050657 3 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
negative regulation of protein phosphorylation GO:0001933 44 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
response to glucose GO:0009749 136 0.011
lipid biosynthetic process GO:0008610 128 0.011
peptidyl amino acid modification GO:0018193 126 0.011
organophosphate catabolic process GO:0046434 148 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
negative regulation of gene expression GO:0010629 199 0.011
regulation of intracellular transport GO:0032386 65 0.011
muscle contraction GO:0006936 88 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
positive regulation of signal transduction GO:0009967 175 0.011
organelle localization GO:0051640 55 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
protein oligomerization GO:0051259 191 0.011
sensory organ development GO:0007423 74 0.011
reproductive structure development GO:0048608 128 0.011
cell cycle process GO:0022402 57 0.011
positive regulation of homeostatic process GO:0032846 49 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
regulation of extent of cell growth GO:0061387 25 0.011
dna replication GO:0006260 37 0.011
calcium ion homeostasis GO:0055074 162 0.011
glucose homeostasis GO:0042593 75 0.011
transmission of nerve impulse GO:0019226 42 0.011
organic anion transport GO:0015711 132 0.011
cellular calcium ion homeostasis GO:0006874 160 0.010
neuronal action potential GO:0019228 35 0.010
ovulation cycle GO:0042698 67 0.010
regulation of response to stress GO:0080134 126 0.010
chromatin organization GO:0006325 34 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
response to calcium ion GO:0051592 59 0.010
cellular ion homeostasis GO:0006873 184 0.010
neurotransmitter gated ion channel clustering GO:0072578 3 0.010
defense response GO:0006952 194 0.010
response to cytokine GO:0034097 215 0.010
regulation of peptide transport GO:0090087 87 0.010
regulation of lipid biosynthetic process GO:0046890 38 0.010
catecholamine transport GO:0051937 37 0.010
positive regulation of growth GO:0045927 55 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
Mouse
phospholipid biosynthetic process GO:0008654 29 0.010
chromatin modification GO:0016568 33 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010

Tsc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.133
nervous system disease DOID:863 0 0.133
central nervous system disease DOID:331 0 0.030
musculoskeletal system disease DOID:17 0 0.028
brain disease DOID:936 0 0.019
parkinson s disease DOID:14330 0 0.018
synucleinopathy DOID:0050890 0 0.018
neurodegenerative disease DOID:1289 0 0.018