Rattus norvegicus

0 known processes

Tspan4

tetraspanin 4

(Aliases: Tm4sf7,MGC108789)

Tspan4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient levels GO:0031667 370 0.359
response to extracellular stimulus GO:0009991 380 0.272
response to cytokine GO:0034097 215 0.179
homeostatic process GO:0042592 331 0.103
regulation of multicellular organismal development GO:2000026 376 0.103
regulation of rna biosynthetic process GO:2001141 381 0.103
positive regulation of cell communication GO:0010647 271 0.100
transcription dna templated GO:0006351 377 0.097
response to nutrient GO:0007584 248 0.096
aging GO:0007568 241 0.094
nucleic acid templated transcription GO:0097659 379 0.087
regulation of cell development GO:0060284 263 0.086
tissue development GO:0009888 252 0.084
regulation of cell proliferation GO:0042127 359 0.081
regulation of cellular component organization GO:0051128 368 0.079
regulation of cell differentiation GO:0045595 320 0.076
regulation of cellular protein metabolic process GO:0032268 267 0.074
rna biosynthetic process GO:0032774 380 0.074
regulation of nervous system development GO:0051960 264 0.069
positive regulation of response to stimulus GO:0048584 285 0.067
cellular response to cytokine stimulus GO:0071345 127 0.065
neuron development GO:0048666 286 0.063
regulation of nucleic acid templated transcription GO:1903506 380 0.063
negative regulation of macromolecule metabolic process GO:0010605 260 0.063
response to acid chemical GO:0001101 222 0.062
regulation of molecular function GO:0065009 398 0.060
positive regulation of multicellular organismal process GO:0051240 387 0.060
negative regulation of cellular metabolic process GO:0031324 281 0.058
cellular amino acid metabolic process GO:0006520 107 0.058
carboxylic acid metabolic process GO:0019752 289 0.056
intracellular signal transduction GO:0035556 314 0.056
cellular amine metabolic process GO:0044106 38 0.054
negative regulation of innate immune response GO:0045824 4 0.053
localization of cell GO:0051674 202 0.053
negative regulation of molecular function GO:0044092 133 0.052
circulatory system development GO:0072359 134 0.052
cell motility GO:0048870 202 0.051
positive regulation of neurogenesis GO:0050769 165 0.051
transcription from rna polymerase ii promoter GO:0006366 252 0.050
inflammatory response GO:0006954 150 0.050
response to other organism GO:0051707 220 0.049
negative regulation of gene expression GO:0010629 199 0.048
positive regulation of nervous system development GO:0051962 178 0.048
positive regulation of developmental process GO:0051094 283 0.048
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.047
rna metabolic process GO:0016070 406 0.047
negative regulation of response to stimulus GO:0048585 155 0.046
organic acid metabolic process GO:0006082 292 0.045
negative regulation of apoptotic process GO:0043066 181 0.045
negative regulation of cell death GO:0060548 229 0.045
positive regulation of cell differentiation GO:0045597 217 0.044
regulation of apoptotic process GO:0042981 335 0.044
regulation of protein metabolic process GO:0051246 289 0.043
cellular component movement GO:0006928 248 0.042
protein phosphorylation GO:0006468 345 0.042
cardiovascular system development GO:0072358 134 0.042
response to lipopolysaccharide GO:0032496 191 0.040
regulation of catalytic activity GO:0050790 304 0.040
response to starvation GO:0042594 59 0.040
chemical homeostasis GO:0048878 292 0.040
negative regulation of programmed cell death GO:0043069 183 0.039
cell projection organization GO:0030030 302 0.039
head development GO:0060322 247 0.038
response to metal ion GO:0010038 253 0.038
single organism catabolic process GO:0044712 283 0.037
response to molecule of bacterial origin GO:0002237 194 0.037
cellular response to stress GO:0033554 269 0.037
response to corticosteroid GO:0031960 235 0.037
positive regulation of signaling GO:0023056 270 0.037
negative regulation of protein metabolic process GO:0051248 114 0.037
rhythmic process GO:0048511 156 0.037
locomotion GO:0040011 237 0.036
regulation of transcription dna templated GO:0006355 374 0.036
neuron projection development GO:0031175 273 0.036
neuron differentiation GO:0030182 368 0.036
amine metabolic process GO:0009308 38 0.036
negative regulation of metabolic process GO:0009892 331 0.036
positive regulation of response to wounding GO:1903036 34 0.035
response to interleukin 1 GO:0070555 55 0.035
positive regulation of cell development GO:0010720 176 0.035
defense response GO:0006952 194 0.035
positive regulation of cell projection organization GO:0031346 111 0.034
cellular component assembly GO:0022607 360 0.034
central nervous system development GO:0007417 311 0.034
reproduction GO:0000003 245 0.033
reproductive process GO:0022414 372 0.033
signal transduction by phosphorylation GO:0023014 144 0.033
positive regulation of cellular component organization GO:0051130 200 0.032
secretion GO:0046903 307 0.032
organelle organization GO:0006996 266 0.032
multicellular organism reproduction GO:0032504 233 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
oxoacid metabolic process GO:0043436 290 0.031
positive regulation of gene expression GO:0010628 244 0.030
regulation of neurogenesis GO:0050767 247 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
brain development GO:0007420 247 0.030
cell migration GO:0016477 197 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
regulation of rna metabolic process GO:0051252 391 0.028
immune response GO:0006955 104 0.028
positive regulation of neuron projection development GO:0010976 99 0.028
cellular response to hormone stimulus GO:0032870 247 0.028
response to tumor necrosis factor GO:0034612 56 0.028
response to biotic stimulus GO:0009607 226 0.028
response to wounding GO:0009611 254 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
regulation of response to stress GO:0080134 126 0.028
regulation of defense response GO:0031347 68 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
response to glucose GO:0009749 136 0.027
cellular response to lipid GO:0071396 201 0.027
programmed cell death GO:0012501 392 0.027
negative regulation of neuron death GO:1901215 69 0.027
regulation of neuron differentiation GO:0045664 208 0.026
positive regulation of signal transduction GO:0009967 175 0.026
multi organism reproductive process GO:0044703 262 0.025
protein homooligomerization GO:0051260 91 0.025
regulation of phosphorylation GO:0042325 248 0.025
response to decreased oxygen levels GO:0036293 237 0.025
reactive oxygen species metabolic process GO:0072593 37 0.025
establishment of protein localization GO:0045184 141 0.025
regulation of cell projection organization GO:0031344 175 0.025
response to carbohydrate GO:0009743 183 0.025
regulation of programmed cell death GO:0043067 341 0.024
catabolic process GO:0009056 351 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
regulation of immune system process GO:0002682 123 0.024
negative regulation of cellular protein metabolic process GO:0032269 106 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
response to peptide hormone GO:0043434 278 0.023
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 13 0.023
neuron death GO:0070997 127 0.023
response to glucocorticoid GO:0051384 223 0.023
vesicle mediated transport GO:0016192 181 0.023
cell growth GO:0016049 104 0.023
response to vitamin GO:0033273 131 0.023
regulation of protein modification process GO:0031399 194 0.023
immune system process GO:0002376 204 0.023
response to hexose GO:0009746 144 0.023
purine containing compound metabolic process GO:0072521 253 0.022
forebrain development GO:0030900 98 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
response to monosaccharide GO:0034284 159 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
response to external biotic stimulus GO:0043207 221 0.021
nucleotide metabolic process GO:0009117 279 0.021
cellular homeostasis GO:0019725 252 0.021
protein complex assembly GO:0006461 263 0.021
macromolecule localization GO:0033036 252 0.020
cell type specific apoptotic process GO:0097285 134 0.020
kidney development GO:0001822 67 0.020
carbohydrate homeostasis GO:0033500 75 0.020
mapk cascade GO:0000165 140 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
regulation of signal transduction GO:0009966 318 0.020
cellular component biogenesis GO:0044085 368 0.020
jak stat cascade GO:0007259 26 0.020
tumor necrosis factor superfamily cytokine production GO:0071706 13 0.020
regulation of inflammatory response GO:0050727 48 0.019
protein localization GO:0008104 191 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
negative regulation of signaling GO:0023057 157 0.019
regulation of locomotion GO:0040012 148 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
response to oxidative stress GO:0006979 186 0.019
vasculature development GO:0001944 70 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.018
protein oligomerization GO:0051259 191 0.018
proteolysis GO:0006508 175 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
response to peptide GO:1901652 292 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
cellular response to external stimulus GO:0071496 118 0.018
regulation of protein phosphorylation GO:0001932 183 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
camera type eye development GO:0043010 48 0.017
response to inorganic substance GO:0010035 377 0.017
gland development GO:0048732 155 0.017
cellular response to alcohol GO:0097306 87 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
epithelial cell differentiation GO:0030855 71 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
growth GO:0040007 165 0.016
cation transport GO:0006812 382 0.016
telencephalon development GO:0021537 62 0.016
cytokine mediated signaling pathway GO:0019221 43 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
regulation of neuron projection development GO:0010975 161 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
organic substance catabolic process GO:1901575 316 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
neuron apoptotic process GO:0051402 88 0.015
protein complex biogenesis GO:0070271 263 0.015
response to estrogen GO:0043627 232 0.015
innate immune response GO:0045087 35 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
response to ketone GO:1901654 182 0.015
sex determination GO:0007530 2 0.015
cellular catabolic process GO:0044248 295 0.015
regeneration GO:0031099 163 0.015
multi multicellular organism process GO:0044706 138 0.014
nitrogen compound transport GO:0071705 229 0.014
single organism reproductive process GO:0044702 297 0.014
apoptotic process GO:0006915 381 0.014
liver development GO:0001889 90 0.014
oxidation reduction process GO:0055114 304 0.014
response to ethanol GO:0045471 162 0.014
macromolecular complex assembly GO:0065003 273 0.014
positive regulation of transport GO:0051050 245 0.014
regulation of growth GO:0040008 105 0.014
regulation of cell migration GO:0030334 128 0.014
organ regeneration GO:0031100 101 0.014
positive regulation of molecular function GO:0044093 230 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
behavior GO:0007610 205 0.014
organophosphate metabolic process GO:0019637 370 0.014
ion transmembrane transport GO:0034220 365 0.014
viral gene expression GO:0019080 2 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
macromolecular complex subunit organization GO:0043933 339 0.013
purine containing compound catabolic process GO:0072523 138 0.013
cellular response to hexose stimulus GO:0071331 65 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
lipid metabolic process GO:0006629 283 0.013
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.013
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.013
gamete generation GO:0007276 124 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
cellular chemical homeostasis GO:0055082 247 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
axis specification GO:0009798 4 0.013
response to estradiol GO:0032355 164 0.013
response to interferon gamma GO:0034341 20 0.013
regulation of response to external stimulus GO:0032101 106 0.013
cellular protein localization GO:0034613 122 0.013
ion homeostasis GO:0050801 212 0.013
regulation of axon extension GO:0030516 24 0.012
regulation of cellular component movement GO:0051270 150 0.012
ameboidal type cell migration GO:0001667 26 0.012
cellular response to lipopolysaccharide GO:0071222 55 0.012
positive regulation of tolerance induction GO:0002645 1 0.012
renal system development GO:0072001 67 0.012
negative regulation of peptidase activity GO:0010466 38 0.012
development of primary sexual characteristics GO:0045137 107 0.012
anion transport GO:0006820 178 0.012
negative regulation of signal transduction GO:0009968 83 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
establishment of tissue polarity GO:0007164 2 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
cellular response to iron ion starvation GO:0010106 1 0.012
cellular response to metal ion GO:0071248 55 0.012
regulation of cytokine production GO:0001817 56 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
positive regulation of protein modification process GO:0031401 142 0.012
negative regulation of immune system process GO:0002683 39 0.012
response to amino acid GO:0043200 75 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
glucose homeostasis GO:0042593 75 0.012
male gamete generation GO:0048232 99 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
ovulation cycle GO:0042698 67 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
epithelium migration GO:0090132 19 0.011
regulation of protein maturation GO:1903317 50 0.011
regulation of tumor necrosis factor production GO:0032680 13 0.011
cation homeostasis GO:0055080 195 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of protein modification process GO:0031400 52 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
single organism biosynthetic process GO:0044711 342 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
cellular response to inorganic substance GO:0071241 65 0.011
negative regulation of transport GO:0051051 136 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
response to bacterium GO:0009617 200 0.011
regulation of viral transcription GO:0046782 2 0.011
regulation of proteolysis GO:0030162 66 0.011
reproductive system development GO:0061458 128 0.011
regulation of cell growth GO:0001558 85 0.010
lung development GO:0030324 43 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
tolerance induction dependent upon immune response GO:0002461 2 0.010
gliogenesis GO:0042063 93 0.010
male gonad development GO:0008584 59 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
regulation of vasculature development GO:1901342 44 0.010
regulation of peptidase activity GO:0052547 55 0.010
negative regulation of developmental process GO:0051093 125 0.010
negative regulation of protein processing GO:0010955 47 0.010
intracellular transport GO:0046907 185 0.010

Tspan4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016