Rattus norvegicus

49 known processes

Ube2b

ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae)

(Aliases: HR6B)

Ube2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acetyl coa biosynthetic process from pyruvate GO:0006086 5 0.269
protein dephosphorylation GO:0006470 38 0.197
ribose phosphate metabolic process GO:0019693 235 0.196
Yeast
regulation of proteasomal protein catabolic process GO:0061136 4 0.196
Fly
regulation of jnk cascade GO:0046328 19 0.190
carboxylic acid metabolic process GO:0019752 289 0.168
acetyl coa metabolic process GO:0006084 17 0.164
organophosphate metabolic process GO:0019637 370 0.163
Yeast
entrainment of circadian clock GO:0009649 3 0.161
regulation of stress activated mapk cascade GO:0032872 23 0.134
purine ribonucleotide metabolic process GO:0009150 227 0.112
Yeast
single organism reproductive process GO:0044702 297 0.111
Mouse
purine nucleotide metabolic process GO:0006163 229 0.105
Yeast
carbohydrate derivative metabolic process GO:1901135 346 0.102
Yeast
sexual reproduction GO:0019953 148 0.098
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.093
intracellular transport GO:0046907 185 0.093
Fly
circadian regulation of gene expression GO:0032922 3 0.093
sulfur compound biosynthetic process GO:0044272 19 0.084
cellular protein catabolic process GO:0044257 19 0.082
regulation of intracellular signal transduction GO:1902531 218 0.081
Human Fly
acyl coa biosynthetic process GO:0071616 7 0.081
cellular macromolecule localization GO:0070727 122 0.081
signal transduction by phosphorylation GO:0023014 144 0.076
wnt signaling pathway GO:0016055 17 0.073
Mouse
single organism catabolic process GO:0044712 283 0.072
Yeast
organophosphate catabolic process GO:0046434 148 0.070
Yeast
reproduction GO:0000003 245 0.070
Yeast Mouse
purine nucleoside metabolic process GO:0042278 169 0.070
Yeast
purine ribonucleoside catabolic process GO:0046130 124 0.069
Yeast
regulation of phosphorus metabolic process GO:0051174 349 0.069
Mouse
amine metabolic process GO:0009308 38 0.069
nucleoside phosphate metabolic process GO:0006753 283 0.067
Yeast
ribonucleotide metabolic process GO:0009259 231 0.066
Yeast
glycosyl compound metabolic process GO:1901657 182 0.064
Yeast
nucleobase containing small molecule metabolic process GO:0055086 316 0.064
Yeast
multicellular organism reproduction GO:0032504 233 0.064
Mouse
acetyl coa biosynthetic process GO:0006085 6 0.063
response to inorganic substance GO:0010035 377 0.063
purine containing compound metabolic process GO:0072521 253 0.061
Yeast
cellular protein localization GO:0034613 122 0.061
nucleotide metabolic process GO:0009117 279 0.061
Yeast
regulation of mapk cascade GO:0043408 116 0.060
ribonucleoside monophosphate metabolic process GO:0009161 88 0.060
Yeast
stress activated mapk cascade GO:0051403 35 0.060
macromolecular complex subunit organization GO:0043933 339 0.059
Human Yeast Mouse Fly
establishment of protein localization GO:0045184 141 0.058
macromolecule catabolic process GO:0009057 58 0.058
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.058
Yeast
apoptotic process GO:0006915 381 0.058
Mouse Fly
nucleoside triphosphate catabolic process GO:0009143 123 0.056
Yeast
organonitrogen compound catabolic process GO:1901565 179 0.056
Yeast
dephosphorylation GO:0016311 98 0.056
cellular component biogenesis GO:0044085 368 0.051
Mouse
purine ribonucleoside metabolic process GO:0046128 168 0.051
Yeast
nucleoside triphosphate metabolic process GO:0009141 144 0.049
Yeast
ribonucleoside metabolic process GO:0009119 174 0.049
Yeast
programmed cell death GO:0012501 392 0.049
Mouse Fly
cellular amino acid metabolic process GO:0006520 107 0.047
purine nucleoside catabolic process GO:0006152 124 0.047
Yeast
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.046
organic substance catabolic process GO:1901575 316 0.045
carbohydrate derivative catabolic process GO:1901136 147 0.044
Yeast
single organism cellular localization GO:1902580 102 0.044
protein oligomerization GO:0051259 191 0.043
positive regulation of biosynthetic process GO:0009891 319 0.043
alternative mrna splicing via spliceosome GO:0000380 4 0.043
single organism biosynthetic process GO:0044711 342 0.042
Yeast
proteolysis GO:0006508 175 0.042
nucleoside metabolic process GO:0009116 179 0.042
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.041
Yeast
nucleoside monophosphate metabolic process GO:0009123 93 0.040
Yeast
purine nucleoside monophosphate metabolic process GO:0009126 84 0.040
Yeast
single organism organelle organization GO:1902589 180 0.040
Human Yeast Mouse Fly
multi organism reproductive process GO:0044703 262 0.040
Mouse
positive regulation of cell migration GO:0030335 96 0.039
protein complex subunit organization GO:0071822 302 0.039
Fly
oxoacid metabolic process GO:0043436 290 0.039
jnk cascade GO:0007254 28 0.038
catabolic process GO:0009056 351 0.038
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.038
aromatic compound catabolic process GO:0019439 168 0.038
Yeast
modification dependent protein catabolic process GO:0019941 14 0.037
regulation of phosphorylation GO:0042325 248 0.036
Mouse
negative regulation of signaling GO:0023057 157 0.036
Human Fly
homeostatic process GO:0042592 331 0.035
Yeast
regulation of cellular amine metabolic process GO:0033238 8 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
Mouse
mitotic spindle organization GO:0007052 2 0.034
Fly
macromolecule localization GO:0033036 252 0.034
ribonucleoside catabolic process GO:0042454 126 0.034
Yeast
regulation of rna biosynthetic process GO:2001141 381 0.034
Yeast Mouse
centrosome organization GO:0051297 1 0.034
Fly
cellular chemical homeostasis GO:0055082 247 0.033
nucleotide catabolic process GO:0009166 139 0.033
Yeast
intracellular protein transport GO:0006886 79 0.033
regulation of protein metabolic process GO:0051246 289 0.033
Mouse Fly
regeneration GO:0031099 163 0.033
cellular response to hormone stimulus GO:0032870 247 0.032
purine ribonucleotide catabolic process GO:0009154 136 0.032
Yeast
cellular component assembly GO:0022607 360 0.032
Mouse
guanosine containing compound catabolic process GO:1901069 71 0.032
ribonucleotide catabolic process GO:0009261 136 0.032
Yeast
regulation of hydrolase activity GO:0051336 143 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
ribonucleoside triphosphate catabolic process GO:0009203 122 0.032
Yeast
nucleoside catabolic process GO:0009164 126 0.031
Yeast
cellular amine metabolic process GO:0044106 38 0.031
glycosyl compound catabolic process GO:1901658 126 0.031
Yeast
mapk cascade GO:0000165 140 0.031
spermatogenesis GO:0007283 99 0.030
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
positive regulation of protein phosphorylation GO:0001934 135 0.030
protein complex biogenesis GO:0070271 263 0.029
coenzyme biosynthetic process GO:0009108 22 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
cellular ketone metabolic process GO:0042180 51 0.029
gastrulation GO:0007369 2 0.028
anatomical structure formation involved in morphogenesis GO:0048646 83 0.028
Mouse
microtubule cytoskeleton organization GO:0000226 25 0.028
Mouse Fly
organ regeneration GO:0031100 101 0.028
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
negative regulation of cell communication GO:0010648 158 0.027
Human Fly
cellular response to endogenous stimulus GO:0071495 377 0.027
regulation of programmed cell death GO:0043067 341 0.027
Mouse Fly
negative regulation of transport GO:0051051 136 0.027
response to nutrient levels GO:0031667 370 0.027
regulation of signal transduction GO:0009966 318 0.027
Human Fly
cytoplasmic transport GO:0016482 115 0.027
gtp metabolic process GO:0046039 72 0.027
protein targeting GO:0006605 61 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
Human Fly
transcription dna templated GO:0006351 377 0.026
Yeast
response to radiation GO:0009314 137 0.026
Human
protein localization to organelle GO:0033365 57 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
Mouse
cellular lipid metabolic process GO:0044255 208 0.026
response to biotic stimulus GO:0009607 226 0.025
negative regulation of phosphate metabolic process GO:0045936 80 0.025
Mouse
guanosine containing compound metabolic process GO:1901068 74 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
cellular response to cytokine stimulus GO:0071345 127 0.025
asymmetric stem cell division GO:0098722 2 0.024
chromosome segregation GO:0007059 2 0.024
cellular catabolic process GO:0044248 295 0.024
thioester biosynthetic process GO:0035384 7 0.024
cell cell signaling GO:0007267 335 0.024
organic acid metabolic process GO:0006082 292 0.024
microtubule organizing center organization GO:0031023 1 0.024
Fly
biological adhesion GO:0022610 110 0.023
organic cyclic compound catabolic process GO:1901361 175 0.023
Yeast
organelle organization GO:0006996 266 0.023
Human Yeast Mouse Fly
positive regulation of protein modification process GO:0031401 142 0.023
gtp catabolic process GO:0006184 71 0.023
rna metabolic process GO:0016070 406 0.022
Yeast
regulation of intracellular transport GO:0032386 65 0.022
negative regulation of phosphorus metabolic process GO:0010563 80 0.022
Mouse
cellular response to stress GO:0033554 269 0.022
Human Yeast Fly
photoperiodism GO:0009648 4 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
Yeast Mouse
regulation of response to stress GO:0080134 126 0.022
Fly
negative regulation of cell death GO:0060548 229 0.022
Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
regulation of canonical wnt signaling pathway GO:0060828 4 0.022
regulation of rna metabolic process GO:0051252 391 0.022
Yeast Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
Mouse
positive regulation of developmental process GO:0051094 283 0.021
regulation of cell differentiation GO:0045595 320 0.021
male gamete generation GO:0048232 99 0.021
Mouse
amide transport GO:0042886 105 0.021
Yeast
divalent inorganic cation transport GO:0072511 134 0.021
cellular nitrogen compound catabolic process GO:0044270 163 0.021
Yeast
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
protein complex assembly GO:0006461 263 0.021
multicellular organismal reproductive process GO:0048609 233 0.020
Mouse
purine nucleotide catabolic process GO:0006195 136 0.020
Yeast
positive regulation of molecular function GO:0044093 230 0.020
blood circulation GO:0008015 183 0.020
response to hypoxia GO:0001666 231 0.020
reactive oxygen species biosynthetic process GO:1903409 8 0.020
macromolecular complex assembly GO:0065003 273 0.020
ras protein signal transduction GO:0007265 29 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
protein phosphorylation GO:0006468 345 0.020
Mouse
positive regulation of transport GO:0051050 245 0.020
establishment of neuroblast polarity GO:0045200 1 0.020
regulation of transferase activity GO:0051338 123 0.020
regulation of protein transport GO:0051223 68 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
cellular response to lipid GO:0071396 201 0.020
negative regulation of metabolic process GO:0009892 331 0.019
Yeast Mouse
calcium ion transport GO:0006816 131 0.019
positive regulation of cell communication GO:0010647 271 0.019
regulation of cell motility GO:2000145 131 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
response to peptide hormone GO:0043434 278 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
Yeast
small gtpase mediated signal transduction GO:0007264 36 0.019
ion transmembrane transport GO:0034220 365 0.019
intracellular signal transduction GO:0035556 314 0.019
Human Fly
alpha amino acid metabolic process GO:1901605 71 0.019
negative regulation of intracellular signal transduction GO:1902532 38 0.019
Human Fly
positive regulation of phosphorylation GO:0042327 177 0.019
single organism intracellular transport GO:1902582 166 0.019
Fly
regulation of cellular ketone metabolic process GO:0010565 27 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
Mouse Fly
cellular response to external stimulus GO:0071496 118 0.018
cellular glucan metabolic process GO:0006073 23 0.018
establishment of organelle localization GO:0051656 37 0.018
response to external biotic stimulus GO:0043207 221 0.018
small molecule biosynthetic process GO:0044283 124 0.018
response to decreased oxygen levels GO:0036293 237 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
Fly
metal ion transport GO:0030001 289 0.018
response to other organism GO:0051707 220 0.018
cellular response to reactive oxygen species GO:0034614 55 0.018
cellular homeostasis GO:0019725 252 0.018
halogenated hydrocarbon metabolic process GO:0042197 4 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.017
Yeast
regulation of cell proliferation GO:0042127 359 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
Yeast
heterocycle catabolic process GO:0046700 167 0.017
Yeast
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
regulation of cell migration GO:0030334 128 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.017
multicellular organism growth GO:0035264 1 0.017
lipid metabolic process GO:0006629 283 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
response to oxidative stress GO:0006979 186 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
Mouse
regulation of protein modification process GO:0031399 194 0.017
Mouse
stress activated protein kinase signaling cascade GO:0031098 37 0.017
cytoskeleton organization GO:0007010 111 0.017
Mouse Fly
protein localization to nucleus GO:0034504 39 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.016
Yeast
autophagy GO:0006914 19 0.016
Fly
brain development GO:0007420 247 0.016
hydrogen peroxide metabolic process GO:0042743 13 0.016
positive regulation of signal transduction GO:0009967 175 0.016
positive regulation of cell death GO:0010942 184 0.016
regulation of immune system process GO:0002682 123 0.016
regulation of molecular function GO:0065009 398 0.016
anterior posterior pattern specification GO:0009952 1 0.016
nucleic acid templated transcription GO:0097659 379 0.016
Yeast
protein catabolic process GO:0030163 30 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
Mouse Fly
muscle tissue development GO:0060537 58 0.016
divalent metal ion transport GO:0070838 132 0.016
nucleocytoplasmic transport GO:0006913 48 0.016
positive regulation of gene expression GO:0010628 244 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.015
cell motility GO:0048870 202 0.015
response to hydrogen peroxide GO:0042542 89 0.015
neuron death GO:0070997 127 0.015
glucan metabolic process GO:0044042 23 0.015
central nervous system development GO:0007417 311 0.015
circulatory system process GO:0003013 183 0.015
regulation of apoptotic process GO:0042981 335 0.015
Mouse Fly
negative regulation of molecular function GO:0044092 133 0.015
neuron apoptotic process GO:0051402 88 0.015
rna biosynthetic process GO:0032774 380 0.015
Yeast
positive regulation of cell development GO:0010720 176 0.015
cellular response to peptide GO:1901653 133 0.015
cell fate determination GO:0001709 2 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
Yeast
endomembrane system organization GO:0010256 48 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.015
Mouse
head development GO:0060322 247 0.015
regulation of dopamine metabolic process GO:0042053 5 0.015
negative regulation of stress activated mapk cascade GO:0032873 4 0.014
regulation of protein kinase activity GO:0045859 105 0.014
negative regulation of gene expression GO:0010629 199 0.014
Yeast Mouse
tissue development GO:0009888 252 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
sulfur compound metabolic process GO:0006790 70 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
response to extracellular stimulus GO:0009991 380 0.014
ion homeostasis GO:0050801 212 0.014
regulation of anatomical structure size GO:0090066 135 0.014
single organismal cell cell adhesion GO:0016337 42 0.014
response to estrogen GO:0043627 232 0.014
regulation of ion transport GO:0043269 245 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
transmembrane transport GO:0055085 412 0.013
autophagic cell death GO:0048102 4 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
aging GO:0007568 241 0.013
regulation of catabolic process GO:0009894 113 0.013
Fly
immune system process GO:0002376 204 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
Mouse Fly
neurological system process GO:0050877 219 0.013
reproductive process GO:0022414 372 0.013
Mouse
cofactor biosynthetic process GO:0051188 28 0.013
pseudopodium organization GO:0031268 3 0.013
response to peptide GO:1901652 292 0.013
synaptic transmission GO:0007268 235 0.013
pigment biosynthetic process GO:0046148 4 0.013
protein localization GO:0008104 191 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
Yeast Mouse
protein transport GO:0015031 132 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.012
positive regulation of signaling GO:0023056 270 0.012
maintenance of location GO:0051235 17 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
Mouse
cell type specific apoptotic process GO:0097285 134 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
axis specification GO:0009798 4 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
response to growth factor GO:0070848 189 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
Fly
response to oxygen levels GO:0070482 265 0.012
peptide transport GO:0015833 97 0.012
Yeast
localization of cell GO:0051674 202 0.012
single organism cell adhesion GO:0098602 46 0.012
regulation of calcium ion transport GO:0051924 77 0.012
cell adhesion GO:0007155 110 0.012
regulation of homeostatic process GO:0032844 101 0.012
cardiovascular system development GO:0072358 134 0.012
growth GO:0040007 165 0.012
response to reactive oxygen species GO:0000302 120 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.011
oxidative phosphorylation GO:0006119 4 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
regulation of cellular localization GO:0060341 263 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
response to vitamin GO:0033273 131 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
Yeast Mouse
positive regulation of cell proliferation GO:0008284 249 0.011
negative regulation of jnk cascade GO:0046329 4 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
Yeast
nitrogen compound transport GO:0071705 229 0.011
Yeast
carboxylic acid transport GO:0046942 115 0.011
regulation of erk1 and erk2 cascade GO:0070372 41 0.011
response to lipopolysaccharide GO:0032496 191 0.011
gland development GO:0048732 155 0.011
cellular response to alcohol GO:0097306 87 0.011
positive regulation of nervous system development GO:0051962 178 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
epithelium development GO:0060429 96 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
negative regulation of cytokine production GO:0001818 16 0.011
nuclear import GO:0051170 35 0.011
actin mediated cell contraction GO:0070252 12 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
positive regulation of kinase activity GO:0033674 77 0.011
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.011
modification dependent macromolecule catabolic process GO:0043632 14 0.010
chemosensory behavior GO:0007635 2 0.010
calcium ion homeostasis GO:0055074 162 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
pyruvate metabolic process GO:0006090 27 0.010
positive regulation of lipid kinase activity GO:0090218 2 0.010
atp metabolic process GO:0046034 72 0.010
Yeast
response to starvation GO:0042594 59 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
Mouse
regulation of cell cycle GO:0051726 73 0.010
Yeast Mouse
posttranscriptional regulation of gene expression GO:0010608 37 0.010
Human
glycogen metabolic process GO:0005977 23 0.010
response to estradiol GO:0032355 164 0.010
response to bacterium GO:0009617 200 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010

Ube2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.033
inherited metabolic disorder DOID:655 0 0.028
disease of anatomical entity DOID:7 0 0.020
muscular disease DOID:0080000 0 0.020
muscle tissue disease DOID:66 0 0.020
musculoskeletal system disease DOID:17 0 0.020
organic acidemia DOID:0060159 0 0.015
amino acid metabolic disorder DOID:9252 0 0.015
muscular dystrophy DOID:9884 0 0.011
myopathy DOID:423 0 0.011
nervous system disease DOID:863 0 0.011