Rattus norvegicus

16 known processes

Ube2d2

ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)

(Aliases: E217kB,Ubc2e)

Ube2d2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of neuron projection development GO:0010975 161 0.284
rna biosynthetic process GO:0032774 380 0.270
cellular component biogenesis GO:0044085 368 0.243
transcription dna templated GO:0006351 377 0.233
regulation of cellular component organization GO:0051128 368 0.211
regulation of neuron differentiation GO:0045664 208 0.199
regulation of neurogenesis GO:0050767 247 0.195
carboxylic acid metabolic process GO:0019752 289 0.192
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.187
organelle organization GO:0006996 266 0.184
carbohydrate metabolic process GO:0005975 130 0.182
regulation of nucleic acid templated transcription GO:1903506 380 0.175
secretion by cell GO:0032940 248 0.172
nucleic acid templated transcription GO:0097659 379 0.167
cell cell signaling GO:0007267 335 0.164
regulation of cell morphogenesis GO:0022604 77 0.164
intracellular transport GO:0046907 185 0.163
cellular component morphogenesis GO:0032989 155 0.148
regulation of transcription dna templated GO:0006355 374 0.145
regulation of nervous system development GO:0051960 264 0.139
cell projection organization GO:0030030 302 0.138
regulation of cell development GO:0060284 263 0.136
regulation of anatomical structure morphogenesis GO:0022603 141 0.134
nitrogen compound transport GO:0071705 229 0.131
positive regulation of signaling GO:0023056 270 0.129
positive regulation of developmental process GO:0051094 283 0.123
central nervous system development GO:0007417 311 0.123
entrainment of circadian clock GO:0009649 3 0.114
neuron differentiation GO:0030182 368 0.107
macromolecule localization GO:0033036 252 0.104
positive regulation of neurogenesis GO:0050769 165 0.103
cell junction maintenance GO:0034331 1 0.101
modification dependent protein catabolic process GO:0019941 14 0.100
positive regulation of cell development GO:0010720 176 0.100
regulation of signal transduction GO:0009966 318 0.100
endocytosis GO:0006897 84 0.099
cellular component assembly GO:0022607 360 0.099
oxoacid metabolic process GO:0043436 290 0.098
cell morphogenesis involved in differentiation GO:0000904 119 0.096
vesicle mediated transport GO:0016192 181 0.092
tissue development GO:0009888 252 0.091
positive regulation of neuron differentiation GO:0045666 126 0.090
negative regulation of cell death GO:0060548 229 0.085
regulation of cell differentiation GO:0045595 320 0.084
single organism intracellular transport GO:1902582 166 0.082
protein complex biogenesis GO:0070271 263 0.081
regulation of cell projection organization GO:0031344 175 0.079
regulation of rna metabolic process GO:0051252 391 0.079
protein complex assembly GO:0006461 263 0.078
response to bacterium GO:0009617 200 0.078
neuron development GO:0048666 286 0.076
positive regulation of cellular component organization GO:0051130 200 0.075
cellular response to growth factor stimulus GO:0071363 162 0.074
cellular response to endogenous stimulus GO:0071495 377 0.074
endosomal transport GO:0016197 14 0.074
regulation of cellular amino acid metabolic process GO:0006521 2 0.073
positive regulation of cell communication GO:0010647 271 0.073
protein complex subunit organization GO:0071822 302 0.072
regulation of dendrite development GO:0050773 59 0.072
protein localization GO:0008104 191 0.071
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.067
negative regulation of biosynthetic process GO:0009890 168 0.066
intracellular signal transduction GO:0035556 314 0.065
negative regulation of response to stimulus GO:0048585 155 0.065
signal release GO:0023061 145 0.064
organic substance catabolic process GO:1901575 316 0.064
positive regulation of cell differentiation GO:0045597 217 0.064
positive regulation of nervous system development GO:0051962 178 0.063
cellular ketone metabolic process GO:0042180 51 0.063
axon development GO:0061564 96 0.063
regulation of cellular component movement GO:0051270 150 0.063
response to peptide GO:1901652 292 0.062
circulatory system development GO:0072359 134 0.062
brain development GO:0007420 247 0.062
response to wounding GO:0009611 254 0.062
single organism behavior GO:0044708 130 0.062
negative regulation of cellular component organization GO:0051129 83 0.061
cellular response to stress GO:0033554 269 0.060
rna metabolic process GO:0016070 406 0.060
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.060
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.060
regulation of cellular localization GO:0060341 263 0.057
negative regulation of signaling GO:0023057 157 0.056
anatomical structure morphogenesis GO:0009653 298 0.056
positive regulation of multicellular organismal process GO:0051240 387 0.056
macromolecular complex subunit organization GO:0043933 339 0.055
response to other organism GO:0051707 220 0.055
regulation of cellular ketone metabolic process GO:0010565 27 0.055
positive regulation of cellular amine metabolic process GO:0033240 3 0.054
chromosome segregation GO:0007059 2 0.053
cell morphogenesis GO:0000902 142 0.053
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.053
positive regulation of cellular component movement GO:0051272 102 0.052
positive regulation of cell proliferation GO:0008284 249 0.052
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.051
cytoplasmic transport GO:0016482 115 0.051
spindle organization GO:0007051 2 0.051
anterior posterior pattern specification GO:0009952 1 0.050
positive regulation of neuron projection development GO:0010976 99 0.050
cellular chemical homeostasis GO:0055082 247 0.050
regulation of phosphorus metabolic process GO:0051174 349 0.049
carbohydrate derivative biosynthetic process GO:1901137 124 0.049
regulation of cellular protein metabolic process GO:0032268 267 0.048
response to ethanol GO:0045471 162 0.048
organelle localization GO:0051640 55 0.048
response to growth factor GO:0070848 189 0.048
organic acid metabolic process GO:0006082 292 0.047
regulation of multicellular organismal development GO:2000026 376 0.047
regulation of protein metabolic process GO:0051246 289 0.047
response to inorganic substance GO:0010035 377 0.047
amine metabolic process GO:0009308 38 0.046
apoptotic process GO:0006915 381 0.046
biological adhesion GO:0022610 110 0.046
regulation of molecular function GO:0065009 398 0.045
head development GO:0060322 247 0.045
regulation of neuron apoptotic process GO:0043523 83 0.045
negative regulation of gene expression GO:0010629 199 0.043
macromolecular complex assembly GO:0065003 273 0.043
homeostatic process GO:0042592 331 0.043
regulation of rna biosynthetic process GO:2001141 381 0.043
cell adhesion GO:0007155 110 0.042
neuron projection development GO:0031175 273 0.042
cellular homeostasis GO:0019725 252 0.042
cell fate determination GO:0001709 2 0.041
regulation of apoptotic process GO:0042981 335 0.041
regulation of hormone secretion GO:0046883 106 0.041
positive regulation of protein metabolic process GO:0051247 178 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.040
single organism organelle organization GO:1902589 180 0.040
secretion GO:0046903 307 0.040
regulation of cellular amine metabolic process GO:0033238 8 0.039
cellular amine metabolic process GO:0044106 38 0.039
positive regulation of response to stimulus GO:0048584 285 0.038
immune system process GO:0002376 204 0.038
regulation of catalytic activity GO:0050790 304 0.038
cardiovascular system development GO:0072358 134 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.037
single organism cellular localization GO:1902580 102 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.037
single organism carbohydrate metabolic process GO:0044723 118 0.036
regulation of cell migration GO:0030334 128 0.036
positive regulation of gene expression GO:0010628 244 0.036
negative regulation of metabolic process GO:0009892 331 0.035
enzyme linked receptor protein signaling pathway GO:0007167 116 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.035
cell part morphogenesis GO:0032990 123 0.035
response to extracellular stimulus GO:0009991 380 0.035
circadian regulation of gene expression GO:0032922 3 0.034
cellular macromolecule localization GO:0070727 122 0.034
positive regulation of biosynthetic process GO:0009891 319 0.034
regulation of phosphorylation GO:0042325 248 0.034
cell type specific apoptotic process GO:0097285 134 0.034
cellular response to lipid GO:0071396 201 0.033
proteolysis GO:0006508 175 0.033
negative regulation of multicellular organismal process GO:0051241 203 0.033
cell growth GO:0016049 104 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.032
immune response GO:0006955 104 0.032
negative regulation of nucleic acid templated transcription GO:1903507 117 0.032
behavioral response to ethanol GO:0048149 1 0.032
modification dependent macromolecule catabolic process GO:0043632 14 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
hormone transport GO:0009914 121 0.031
neurological system process GO:0050877 219 0.030
dendrite development GO:0016358 72 0.030
single organism biosynthetic process GO:0044711 342 0.030
axis specification GO:0009798 4 0.030
regulation of synaptic transmission GO:0050804 141 0.030
negative regulation of transport GO:0051051 136 0.030
cellular protein localization GO:0034613 122 0.030
single organism reproductive process GO:0044702 297 0.029
regulation of locomotion GO:0040012 148 0.029
positive regulation of cell projection organization GO:0031346 111 0.029
response to oxidative stress GO:0006979 186 0.029
cell projection morphogenesis GO:0048858 123 0.029
cellular protein complex assembly GO:0043623 44 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
regulation of intracellular transport GO:0032386 65 0.028
multicellular organism reproduction GO:0032504 233 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
mitotic spindle organization GO:0007052 2 0.028
organelle assembly GO:0070925 22 0.028
cellular ion homeostasis GO:0006873 184 0.027
adult behavior GO:0030534 16 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.027
cytoskeleton organization GO:0007010 111 0.027
protein phosphorylation GO:0006468 345 0.027
response to external biotic stimulus GO:0043207 221 0.027
regulation of growth GO:0040008 105 0.027
positive regulation of cytoplasmic transport GO:1903651 32 0.027
growth GO:0040007 165 0.026
regeneration GO:0031099 163 0.026
vesicle organization GO:0016050 29 0.026
protein targeting GO:0006605 61 0.026
negative regulation of transcription dna templated GO:0045892 116 0.026
response to peptide hormone GO:0043434 278 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
cellular macromolecular complex assembly GO:0034622 58 0.025
negative regulation of molecular function GO:0044092 133 0.025
regulation of cell proliferation GO:0042127 359 0.025
neuron apoptotic process GO:0051402 88 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.024
synaptic transmission GO:0007268 235 0.024
negative regulation of phosphate metabolic process GO:0045936 80 0.024
positive regulation of signal transduction GO:0009967 175 0.024
negative regulation of rna metabolic process GO:0051253 123 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
circadian rhythm GO:0007623 88 0.023
chemical homeostasis GO:0048878 292 0.023
receptor mediated endocytosis GO:0006898 42 0.023
embryonic pattern specification GO:0009880 1 0.023
rhythmic process GO:0048511 156 0.023
regulation of peptide secretion GO:0002791 82 0.023
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.023
reproduction GO:0000003 245 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
cellular catabolic process GO:0044248 295 0.022
muscle cell proliferation GO:0033002 84 0.022
regulation of secretion GO:0051046 224 0.022
negative regulation of cell communication GO:0010648 158 0.022
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.022
multi organism reproductive process GO:0044703 262 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
regulation of circadian rhythm GO:0042752 27 0.021
locomotion GO:0040011 237 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
reproductive process GO:0022414 372 0.021
centrosome localization GO:0051642 1 0.021
dephosphorylation GO:0016311 98 0.021
catabolic process GO:0009056 351 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.020
gastrulation GO:0007369 2 0.020
heart development GO:0007507 72 0.020
single organism catabolic process GO:0044712 283 0.020
response to monosaccharide GO:0034284 159 0.020
regulation of hormone levels GO:0010817 187 0.020
negative regulation of neuron death GO:1901215 69 0.020
regulation of protein modification process GO:0031399 194 0.019
neuron projection morphogenesis GO:0048812 122 0.019
bmp signaling pathway GO:0030509 4 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
negative regulation of signal transduction GO:0009968 83 0.019
regulation of cytokine production GO:0001817 56 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
regulation of cellular component biogenesis GO:0044087 86 0.019
response to acid chemical GO:0001101 222 0.019
cell cycle GO:0007049 101 0.019
sexual reproduction GO:0019953 148 0.019
regulation of stem cell differentiation GO:2000736 2 0.018
exocytosis GO:0006887 60 0.018
regulation of synaptic plasticity GO:0048167 70 0.018
developmental process involved in reproduction GO:0003006 159 0.018
embryo development GO:0009790 49 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.018
meiotic cell cycle process GO:1903046 3 0.018
central nervous system neuron axonogenesis GO:0021955 1 0.018
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.018
anion transport GO:0006820 178 0.018
hormone secretion GO:0046879 115 0.018
tissue regeneration GO:0042246 36 0.018
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
negative regulation of dendrite development GO:2000171 9 0.017
monosaccharide metabolic process GO:0005996 61 0.017
response to retinoic acid GO:0032526 63 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
cellular response to ammonium ion GO:0071242 17 0.017
negative regulation of developmental process GO:0051093 125 0.017
positive regulation of cell motility GO:2000147 97 0.017
ras protein signal transduction GO:0007265 29 0.017
cellular response to oxidative stress GO:0034599 76 0.017
regulation of axonogenesis GO:0050770 37 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
positive regulation of secretion GO:0051047 140 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
cell junction organization GO:0034330 21 0.016
positive regulation of transport GO:0051050 245 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
leukocyte activation GO:0045321 76 0.016
programmed cell death GO:0012501 392 0.016
positive regulation of peptide secretion GO:0002793 52 0.016
peptidyl tyrosine phosphorylation GO:0018108 72 0.016
nucleocytoplasmic transport GO:0006913 48 0.016
defense response GO:0006952 194 0.016
cellular response to external stimulus GO:0071496 118 0.016
axonogenesis GO:0007409 71 0.016
gamete generation GO:0007276 124 0.016
ion homeostasis GO:0050801 212 0.016
cognition GO:0050890 92 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
behavior GO:0007610 205 0.016
neuron projection extension GO:1990138 26 0.015
single organism membrane organization GO:0044802 74 0.015
membrane organization GO:0061024 94 0.015
cytokine production GO:0001816 61 0.015
chemosensory behavior GO:0007635 2 0.015
response to oxygen levels GO:0070482 265 0.015
fatty acid metabolic process GO:0006631 99 0.015
macromolecule catabolic process GO:0009057 58 0.015
vasculature development GO:0001944 70 0.015
response to glucose GO:0009749 136 0.015
negative regulation of nervous system development GO:0051961 79 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.015
establishment of protein localization GO:0045184 141 0.015
peptide transport GO:0015833 97 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
regulation of cell motility GO:2000145 131 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
regulation of neuron death GO:1901214 115 0.014
peptidyl amino acid modification GO:0018193 126 0.014
cortical actin cytoskeleton organization GO:0030866 2 0.014
regulation of mapk cascade GO:0043408 116 0.014
cellular response to alcohol GO:0097306 87 0.014
protein modification by small protein conjugation GO:0032446 31 0.014
organ morphogenesis GO:0009887 75 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
regulation of small gtpase mediated signal transduction GO:0051056 48 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
calcium ion dependent exocytosis GO:0017156 16 0.014
cellular response to acid chemical GO:0071229 75 0.013
protein modification by small protein conjugation or removal GO:0070647 35 0.013
dna metabolic process GO:0006259 96 0.013
cell motility GO:0048870 202 0.013
neuron death GO:0070997 127 0.013
gliogenesis GO:0042063 93 0.013
rna localization GO:0006403 4 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
learning or memory GO:0007611 90 0.013
cytokinetic process GO:0032506 1 0.013
cellular cation homeostasis GO:0030003 180 0.013
regulation of protein localization GO:0032880 81 0.013
protein localization to organelle GO:0033365 57 0.013
amide transport GO:0042886 105 0.013
cellular component maintenance GO:0043954 4 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
glucose homeostasis GO:0042593 75 0.013
golgi vesicle transport GO:0048193 22 0.013
cellular response to heat GO:0034605 9 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
gland development GO:0048732 155 0.013
regulation of cell growth GO:0001558 85 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
cofactor biosynthetic process GO:0051188 28 0.012
early endosome to late endosome transport GO:0045022 2 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
olfactory learning GO:0008355 1 0.012
positive regulation of stem cell differentiation GO:2000738 2 0.012
mammary gland epithelium development GO:0061180 1 0.012
positive regulation of peptide hormone secretion GO:0090277 50 0.012
regulation of homeostatic process GO:0032844 101 0.012
regulation of peptide transport GO:0090087 87 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
response to transforming growth factor beta GO:0071559 46 0.012
response to hypoxia GO:0001666 231 0.012
neural precursor cell proliferation GO:0061351 23 0.012
hemopoiesis GO:0030097 34 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
cell cell junction organization GO:0045216 20 0.012
regulation of dendrite morphogenesis GO:0048814 33 0.012
regulation of neuronal synaptic plasticity GO:0048168 31 0.012
male gamete generation GO:0048232 99 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of secretion by cell GO:1903530 208 0.012
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.012
multi multicellular organism process GO:0044706 138 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
regulation of smooth muscle cell migration GO:0014910 36 0.012
melanosome localization GO:0032400 1 0.012
carbohydrate homeostasis GO:0033500 75 0.012
actin cytoskeleton organization GO:0030036 73 0.011
microtubule cytoskeleton organization GO:0000226 25 0.011
positive regulation of transcription factor import into nucleus GO:0042993 4 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
posttranscriptional regulation of gene expression GO:0010608 37 0.011
protein dephosphorylation GO:0006470 38 0.011
glucose metabolic process GO:0006006 52 0.011
metal ion homeostasis GO:0055065 186 0.011
wound healing GO:0042060 122 0.011
regulation of anatomical structure size GO:0090066 135 0.011
cellular component movement GO:0006928 248 0.011
regulation of dendritic spine development GO:0060998 16 0.011
sulfur compound metabolic process GO:0006790 70 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
sensory organ development GO:0007423 74 0.011
female pregnancy GO:0007565 122 0.011
positive regulation of intracellular transport GO:0032388 39 0.011
endosome organization GO:0007032 3 0.011
intracellular protein transport GO:0006886 79 0.011
tumor necrosis factor superfamily cytokine production GO:0071706 13 0.011
cell cycle process GO:0022402 57 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
cell migration GO:0016477 197 0.010
regulation of receptor mediated endocytosis GO:0048259 17 0.010
ribose phosphate metabolic process GO:0019693 235 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
regulation of insulin secretion GO:0050796 65 0.010
positive regulation of glycoprotein metabolic process GO:1903020 3 0.010
cellular response to drug GO:0035690 30 0.010
response to reactive oxygen species GO:0000302 120 0.010
spermatogenesis GO:0007283 99 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
mrna stabilization GO:0048255 2 0.010
developmental growth GO:0048589 100 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
organic anion transport GO:0015711 132 0.010

Ube2d2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
nervous system disease DOID:863 0 0.011
bone disease DOID:0080001 0 0.010