Rattus norvegicus

0 known processes

Unc45b

unc-45 homolog B (C. elegans)

(Aliases: Cmya4)

Unc45b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.196
cellular component biogenesis GO:0044085 368 0.175
cytoskeleton organization GO:0007010 111 0.129
positive regulation of neurogenesis GO:0050769 165 0.128
cellular response to endogenous stimulus GO:0071495 377 0.108
regulation of cell differentiation GO:0045595 320 0.101
positive regulation of developmental process GO:0051094 283 0.096
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.093
cellular component assembly GO:0022607 360 0.082
response to estrogen GO:0043627 232 0.073
cellular component morphogenesis GO:0032989 155 0.073
positive regulation of biosynthetic process GO:0009891 319 0.070
regulation of nervous system development GO:0051960 264 0.069
regulation of cell morphogenesis GO:0022604 77 0.068
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.067
neuron differentiation GO:0030182 368 0.063
enzyme linked receptor protein signaling pathway GO:0007167 116 0.063
response to corticosteroid GO:0031960 235 0.060
regulation of cellular component organization GO:0051128 368 0.058
circadian sleep wake cycle process GO:0022410 21 0.055
regulation of neuron projection development GO:0010975 161 0.053
cellular response to stress GO:0033554 269 0.053
regulation of cell development GO:0060284 263 0.052
actin cytoskeleton organization GO:0030036 73 0.051
response to estradiol GO:0032355 164 0.049
response to blue light GO:0009637 1 0.049
cell projection organization GO:0030030 302 0.047
regulation of neuron differentiation GO:0045664 208 0.046
macromolecular complex subunit organization GO:0043933 339 0.045
cell projection morphogenesis GO:0048858 123 0.045
response to inorganic substance GO:0010035 377 0.043
positive regulation of cell development GO:0010720 176 0.042
neuron projection morphogenesis GO:0048812 122 0.041
regulation of neurogenesis GO:0050767 247 0.041
regulation of cell projection organization GO:0031344 175 0.040
cellular response to organonitrogen compound GO:0071417 197 0.038
response to ionizing radiation GO:0010212 59 0.038
cellular response to hormone stimulus GO:0032870 247 0.038
intracellular transport GO:0046907 185 0.038
central nervous system development GO:0007417 311 0.037
organelle organization GO:0006996 266 0.037
response to electrical stimulus involved in regulation of muscle adaptation GO:0014878 4 0.036
circadian rhythm GO:0007623 88 0.036
response to nutrient levels GO:0031667 370 0.036
cellular response to growth factor stimulus GO:0071363 162 0.036
cellular response to organic cyclic compound GO:0071407 202 0.036
regulation of rna biosynthetic process GO:2001141 381 0.035
cardiac muscle tissue morphogenesis GO:0055008 1 0.035
response to peptide hormone GO:0043434 278 0.034
anatomical structure morphogenesis GO:0009653 298 0.033
homeostatic process GO:0042592 331 0.033
negative regulation of metabolic process GO:0009892 331 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
muscle structure development GO:0061061 87 0.032
sequestering of calcium ion GO:0051208 8 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
response to hypoxia GO:0001666 231 0.032
cation transport GO:0006812 382 0.031
sequestering of metal ion GO:0051238 9 0.031
membrane depolarization during action potential GO:0086010 1 0.031
response to oxygen levels GO:0070482 265 0.031
transmembrane transport GO:0055085 412 0.030
negative regulation of biosynthetic process GO:0009890 168 0.030
rhythmic process GO:0048511 156 0.030
response to decreased oxygen levels GO:0036293 237 0.030
endoplasmic reticulum to cytosol transport GO:1903513 4 0.030
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.029
rna biosynthetic process GO:0032774 380 0.029
gland development GO:0048732 155 0.029
positive regulation of cellular component organization GO:0051130 200 0.029
cellular response to nitrogen compound GO:1901699 210 0.028
cellular component movement GO:0006928 248 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.028
calcium ion homeostasis GO:0055074 162 0.028
inorganic ion transmembrane transport GO:0098660 229 0.028
apoptotic process GO:0006915 381 0.027
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.027
eosinophil migration GO:0072677 3 0.027
aging GO:0007568 241 0.027
regulation of transporter activity GO:0032409 50 0.026
cardiac chamber development GO:0003205 1 0.026
positive regulation of nervous system development GO:0051962 178 0.026
cation transmembrane transport GO:0098655 263 0.026
regulation of transcription dna templated GO:0006355 374 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
cytoplasmic transport GO:0016482 115 0.026
response to ketone GO:1901654 182 0.025
programmed cell death GO:0012501 392 0.025
chemical homeostasis GO:0048878 292 0.025
muscle system process GO:0003012 115 0.025
positive regulation of neuron differentiation GO:0045666 126 0.025
single organism organelle organization GO:1902589 180 0.025
positive regulation of jnk cascade GO:0046330 13 0.025
brain development GO:0007420 247 0.024
head development GO:0060322 247 0.024
rna metabolic process GO:0016070 406 0.024
neuron projection development GO:0031175 273 0.024
tissue development GO:0009888 252 0.024
positive regulation of heart contraction GO:0045823 15 0.024
cardiac ventricle development GO:0003231 1 0.024
regulation of system process GO:0044057 208 0.024
protein oligomerization GO:0051259 191 0.023
circulatory system development GO:0072359 134 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
adult locomotory behavior GO:0008344 4 0.022
actin filament based process GO:0030029 86 0.022
response to calcium ion GO:0051592 59 0.022
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.022
response to peptide GO:1901652 292 0.021
cellular response to alkaloid GO:0071312 25 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.021
cell part morphogenesis GO:0032990 123 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
response to growth factor GO:0070848 189 0.021
response to cytokine GO:0034097 215 0.021
regulation of sodium ion transport GO:0002028 21 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
heart process GO:0003015 57 0.020
cellular homeostasis GO:0019725 252 0.020
ras protein signal transduction GO:0007265 29 0.020
response to extracellular stimulus GO:0009991 380 0.020
reproduction GO:0000003 245 0.020
sodium ion transmembrane transport GO:0035725 67 0.020
locomotion GO:0040011 237 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
negative regulation of homeostatic process GO:0032845 47 0.019
heart contraction GO:0060047 57 0.019
cell migration GO:0016477 197 0.019
positive regulation of gene expression GO:0010628 244 0.019
cellular response to peptide GO:1901653 133 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.018
regulation of bmp signaling pathway GO:0030510 2 0.018
regulation of establishment of planar polarity GO:0090175 2 0.018
cardiac conduction GO:0061337 2 0.018
release of sequestered calcium ion into cytosol GO:0051209 25 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
axonogenesis GO:0007409 71 0.017
regulation of stem cell differentiation GO:2000736 2 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 2 0.017
positive regulation of phagocytosis engulfment GO:0060100 4 0.017
regulation of dendrite development GO:0050773 59 0.017
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.017
response to ethanol GO:0045471 162 0.017
cellular cation homeostasis GO:0030003 180 0.017
positive regulation of transcription dna templated GO:0045893 197 0.016
muscle cell differentiation GO:0042692 52 0.016
growth GO:0040007 165 0.016
organic cation transport GO:0015695 11 0.016
bmp signaling pathway GO:0030509 4 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
choline transport GO:0015871 4 0.016
ion transmembrane transport GO:0034220 365 0.016
neuron development GO:0048666 286 0.016
negative regulation of gene expression GO:0010629 199 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
carbohydrate metabolic process GO:0005975 130 0.015
protein complex subunit organization GO:0071822 302 0.015
cellular ion homeostasis GO:0006873 184 0.015
transcription dna templated GO:0006351 377 0.015
maintenance of location GO:0051235 17 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
response to biotic stimulus GO:0009607 226 0.015
response to toxic substance GO:0009636 133 0.015
negative regulation of innate immune response GO:0045824 4 0.015
ion homeostasis GO:0050801 212 0.015
regulation of hormone levels GO:0010817 187 0.015
reproductive system development GO:0061458 128 0.015
response to organophosphorus GO:0046683 102 0.015
cell morphogenesis GO:0000902 142 0.015
intracellular signal transduction GO:0035556 314 0.015
negative regulation of chronic inflammatory response GO:0002677 2 0.015
metal ion transport GO:0030001 289 0.014
multicellular organism reproduction GO:0032504 233 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
negative regulation of ion transmembrane transport GO:0034766 16 0.014
sodium ion transport GO:0006814 82 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
regulation of heart contraction GO:0008016 48 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
developmental growth GO:0048589 100 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
synapse organization GO:0050808 46 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
calcium ion transmembrane transport GO:0070588 70 0.014
response to metal ion GO:0010038 253 0.014
endoplasmic reticulum membrane organization GO:0090158 1 0.014
heart development GO:0007507 72 0.014
axis specification GO:0009798 4 0.014
regulation of cardiac muscle contraction GO:0055117 17 0.014
protein complex assembly GO:0006461 263 0.013
negative regulation of hormone secretion GO:0046888 46 0.013
regulation of muscle system process GO:0090257 79 0.013
response to radiation GO:0009314 137 0.013
cell communication involved in cardiac conduction GO:0086065 2 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
rhythmic behavior GO:0007622 24 0.013
regulation of ion transport GO:0043269 245 0.013
negative regulation of neuron death GO:1901215 69 0.013
liver development GO:0001889 90 0.013
cardiac myofibril assembly GO:0055003 1 0.013
response to insulin GO:0032868 133 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
response to carbohydrate GO:0009743 183 0.013
cytosolic calcium ion transport GO:0060401 39 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.013
regulation of metal ion transport GO:0010959 118 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
dendrite development GO:0016358 72 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
response to other organism GO:0051707 220 0.012
cellular amine metabolic process GO:0044106 38 0.012
metal ion homeostasis GO:0055065 186 0.012
circadian sleep wake cycle GO:0042745 23 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
nucleotide metabolic process GO:0009117 279 0.012
response to glucocorticoid GO:0051384 223 0.012
regulation of membrane potential GO:0042391 110 0.012
lipid metabolic process GO:0006629 283 0.011
organic anion transport GO:0015711 132 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
protein complex biogenesis GO:0070271 263 0.011
calcium ion transport into cytosol GO:0060402 38 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
rho protein signal transduction GO:0007266 11 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
negative regulation of circadian sleep wake cycle sleep GO:0042321 5 0.011
developmental process involved in reproduction GO:0003006 159 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
oxidation reduction process GO:0055114 304 0.011
endoplasmic reticulum organization GO:0007029 1 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
response to alkaloid GO:0043279 132 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.010
reproductive structure development GO:0048608 128 0.010
response to reactive oxygen species GO:0000302 120 0.010
macromolecular complex assembly GO:0065003 273 0.010
response to testosterone GO:0033574 55 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010

Unc45b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.158
cardiovascular system disease DOID:1287 0 0.158
myopathy DOID:423 0 0.130
muscular disease DOID:0080000 0 0.130
heart disease DOID:114 0 0.130
cardiomyopathy DOID:0050700 0 0.130
musculoskeletal system disease DOID:17 0 0.130
muscle tissue disease DOID:66 0 0.130
dilated cardiomyopathy DOID:12930 0 0.048
intrinsic cardiomyopathy DOID:0060036 0 0.048
disease of metabolism DOID:0014667 0 0.028
inherited metabolic disorder DOID:655 0 0.028
nervous system disease DOID:863 0 0.015