Rattus norvegicus

52 known processes

Unc5a

unc-5 homolog A (C. elegans)

(Aliases: Unc5h1)

Unc5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling GO:0007267 335 0.899
vesicle mediated transport GO:0016192 181 0.442
synaptic vesicle exocytosis GO:0016079 15 0.432
apoptotic process GO:0006915 381 0.410
Rat
regulation of phosphate metabolic process GO:0019220 349 0.377
glutamate receptor signaling pathway GO:0007215 43 0.373
positive regulation of transport GO:0051050 245 0.354
regulation of signal transduction GO:0009966 318 0.331
Rat
regulation of exocytosis GO:0017157 37 0.300
exocytosis GO:0006887 60 0.290
phosphatidylinositol dephosphorylation GO:0046856 4 0.285
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.269
regulation of phosphorus metabolic process GO:0051174 349 0.267
behavior GO:0007610 205 0.259
membrane organization GO:0061024 94 0.258
neurotransmitter secretion GO:0007269 33 0.257
regulation of ion transport GO:0043269 245 0.254
secretion by cell GO:0032940 248 0.242
secretion GO:0046903 307 0.232
intracellular signal transduction GO:0035556 314 0.222
signal release GO:0023061 145 0.212
insulin secretion GO:0030073 69 0.204
cellular component assembly GO:0022607 360 0.200
brain development GO:0007420 247 0.197
single organism behavior GO:0044708 130 0.191
purine ribonucleotide biosynthetic process GO:0009152 81 0.191
synaptic transmission GO:0007268 235 0.190
regulation of programmed cell death GO:0043067 341 0.190
Rat
metal ion transport GO:0030001 289 0.184
regulation of neurotransmitter secretion GO:0046928 19 0.182
establishment of organelle localization GO:0051656 37 0.182
synapse organization GO:0050808 46 0.179
organophosphate metabolic process GO:0019637 370 0.178
cellular response to peptide GO:1901653 133 0.175
response to carbohydrate GO:0009743 183 0.172
regulation of molecular function GO:0065009 398 0.171
regulation of synaptic transmission GO:0050804 141 0.170
macromolecular complex subunit organization GO:0043933 339 0.170
regulation of cellular localization GO:0060341 263 0.169
regulation of peptide transport GO:0090087 87 0.167
regulation of neuron projection development GO:0010975 161 0.166
Worm
cell projection organization GO:0030030 302 0.161
neurotransmitter transport GO:0006836 42 0.159
nucleoside phosphate metabolic process GO:0006753 283 0.153
negative regulation of vesicle fusion GO:0031339 2 0.151
negative regulation of cell communication GO:0010648 158 0.150
regulation of cellular component organization GO:0051128 368 0.148
Worm
negative regulation of cell death GO:0060548 229 0.148
neuron differentiation GO:0030182 368 0.140
regulation of membrane potential GO:0042391 110 0.137
monovalent inorganic cation transport GO:0015672 172 0.133
regulation of synaptic vesicle endocytosis GO:1900242 1 0.130
protein complex subunit organization GO:0071822 302 0.129
positive regulation of response to stimulus GO:0048584 285 0.129
Rat
establishment of synaptic vesicle localization GO:0097480 23 0.124
protein localization GO:0008104 191 0.124
cellular homeostasis GO:0019725 252 0.124
regulation of synaptic vesicle exocytosis GO:2000300 6 0.123
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.123
cation transport GO:0006812 382 0.123
negative regulation of signaling GO:0023057 157 0.122
potassium ion transport GO:0006813 97 0.122
regulation of protein localization GO:0032880 81 0.120
regulation of cell differentiation GO:0045595 320 0.119
Worm
negative regulation of apoptotic process GO:0043066 181 0.118
ribose phosphate metabolic process GO:0019693 235 0.117
neurological system process GO:0050877 219 0.115
positive regulation of nervous system development GO:0051962 178 0.115
Worm
central nervous system development GO:0007417 311 0.113
inorganic cation transmembrane transport GO:0098662 202 0.113
carbohydrate derivative metabolic process GO:1901135 346 0.110
negative regulation of metabolic process GO:0009892 331 0.110
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.109
regulation of postsynaptic membrane potential GO:0060078 25 0.108
positive regulation of protein phosphorylation GO:0001934 135 0.107
peptide secretion GO:0002790 86 0.107
regulation of secretion GO:0051046 224 0.107
regulation of neuron apoptotic process GO:0043523 83 0.106
neuron death GO:0070997 127 0.106
regulation of calcium ion dependent exocytosis GO:0017158 11 0.104
cellular component biogenesis GO:0044085 368 0.102
negative regulation of transport GO:0051051 136 0.102
divalent inorganic cation transport GO:0072511 134 0.101
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.099
ribonucleotide metabolic process GO:0009259 231 0.099
regulation of secretion by cell GO:1903530 208 0.098
single organism membrane organization GO:0044802 74 0.098
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.098
spinal cord development GO:0021510 27 0.095
protein transport GO:0015031 132 0.094
regulation of vesicle mediated transport GO:0060627 81 0.093
nucleobase containing small molecule metabolic process GO:0055086 316 0.092
response to hexose GO:0009746 144 0.092
cellular protein localization GO:0034613 122 0.092
regulation of establishment of protein localization GO:0070201 69 0.090
ion transmembrane transport GO:0034220 365 0.086
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.086
establishment of protein localization GO:0045184 141 0.086
macromolecule localization GO:0033036 252 0.086
cell type specific apoptotic process GO:0097285 134 0.086
regulation of apoptotic process GO:0042981 335 0.085
Rat
carbohydrate metabolic process GO:0005975 130 0.083
nucleotide metabolic process GO:0009117 279 0.083
vesicle fusion GO:0006906 14 0.083
nucleoside phosphate biosynthetic process GO:1901293 102 0.083
regulation of intracellular signal transduction GO:1902531 218 0.081
ribose phosphate biosynthetic process GO:0046390 87 0.081
purine nucleotide biosynthetic process GO:0006164 83 0.080
divalent metal ion transport GO:0070838 132 0.079
inorganic ion transmembrane transport GO:0098660 229 0.079
positive regulation of cell differentiation GO:0045597 217 0.078
Worm
positive regulation of excitatory postsynaptic membrane potential GO:2000463 7 0.078
regulation of protein transport GO:0051223 68 0.078
response to hypoxia GO:0001666 231 0.077
regulation of metal ion transport GO:0010959 118 0.077
positive regulation of phosphorus metabolic process GO:0010562 262 0.076
protein complex assembly GO:0006461 263 0.076
vesicle organization GO:0016050 29 0.076
intracellular protein transport GO:0006886 79 0.075
positive regulation of phosphate metabolic process GO:0045937 262 0.075
transmembrane transport GO:0055085 412 0.074
neuromuscular process GO:0050905 2 0.074
positive regulation of signal transduction GO:0009967 175 0.074
Rat
response to oxygen levels GO:0070482 265 0.074
organelle organization GO:0006996 266 0.074
programmed cell death GO:0012501 392 0.074
Rat
positive regulation of programmed cell death GO:0043068 157 0.073
Rat
peptide transport GO:0015833 97 0.072
growth GO:0040007 165 0.071
Worm
cellular carbohydrate metabolic process GO:0044262 72 0.071
positive regulation of biosynthetic process GO:0009891 319 0.071
regulation of cellular protein metabolic process GO:0032268 267 0.071
negative regulation of programmed cell death GO:0043069 183 0.070
cell growth GO:0016049 104 0.069
Worm
cellular response to endogenous stimulus GO:0071495 377 0.069
positive regulation of membrane potential GO:0045838 16 0.069
positive regulation of developmental process GO:0051094 283 0.069
Worm
positive regulation of calcium ion dependent exocytosis GO:0045956 6 0.068
forebrain development GO:0030900 98 0.068
nitrogen compound transport GO:0071705 229 0.068
calcium ion homeostasis GO:0055074 162 0.068
organic substance catabolic process GO:1901575 316 0.067
Worm
regulation of protein metabolic process GO:0051246 289 0.067
response to monosaccharide GO:0034284 159 0.067
regulation of rna metabolic process GO:0051252 391 0.067
positive regulation of molecular function GO:0044093 230 0.066
regulation of synaptic plasticity GO:0048167 70 0.065
rhythmic synaptic transmission GO:0060024 1 0.065
calcium ion dependent exocytosis GO:0017156 16 0.064
response to nutrient levels GO:0031667 370 0.064
response to inorganic substance GO:0010035 377 0.063
ribonucleoside triphosphate metabolic process GO:0009199 141 0.063
positive regulation of apoptotic process GO:0043065 154 0.063
Rat
regulation of catalytic activity GO:0050790 304 0.063
detection of chemical stimulus GO:0009593 10 0.063
regulation of nucleic acid templated transcription GO:1903506 380 0.062
protein phosphorylation GO:0006468 345 0.062
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.061
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.061
postsynaptic density protein 95 clustering GO:0097119 2 0.061
positive regulation of signaling GO:0023056 270 0.061
Rat
somatostatin signaling pathway GO:0038170 4 0.061
positive regulation of phosphorylation GO:0042327 177 0.060
positive regulation of cell proliferation GO:0008284 249 0.060
negative regulation of response to stimulus GO:0048585 155 0.059
positive regulation of dendritic spine development GO:0060999 9 0.059
intracellular transport GO:0046907 185 0.059
cerebellar purkinje cell layer morphogenesis GO:0021692 1 0.059
negative regulation of secretion by cell GO:1903531 72 0.058
nucleoside metabolic process GO:0009116 179 0.058
cell part morphogenesis GO:0032990 123 0.058
regulation of cell projection organization GO:0031344 175 0.058
Worm
neuron development GO:0048666 286 0.057
positive regulation of nucleic acid templated transcription GO:1903508 197 0.057
membrane fusion GO:0061025 26 0.057
regulation of cell proliferation GO:0042127 359 0.057
organelle localization GO:0051640 55 0.056
regulation of potassium ion transport GO:0043266 29 0.056
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.056
purine nucleotide catabolic process GO:0006195 136 0.055
adult locomotory behavior GO:0008344 4 0.055
lymphoid progenitor cell differentiation GO:0002320 2 0.055
auditory receptor cell differentiation GO:0042491 2 0.054
detection of calcium ion GO:0005513 1 0.054
regulation of nucleotide metabolic process GO:0006140 117 0.054
single organism cellular localization GO:1902580 102 0.054
organelle fusion GO:0048284 17 0.054
neuron projection morphogenesis GO:0048812 122 0.053
positive regulation of secretion GO:0051047 140 0.053
regulation of neuron death GO:1901214 115 0.052
synaptic vesicle localization GO:0097479 24 0.052
cellular response to organonitrogen compound GO:0071417 197 0.052
positive regulation of nucleotide metabolic process GO:0045981 91 0.051
neuronal ion channel clustering GO:0045161 3 0.051
cell morphogenesis involved in differentiation GO:0000904 119 0.051
response to glucose GO:0009749 136 0.049
regulation of peptide secretion GO:0002791 82 0.049
cellular response to stress GO:0033554 269 0.049
cellular response to organic cyclic compound GO:0071407 202 0.049
response to decreased oxygen levels GO:0036293 237 0.049
nucleic acid templated transcription GO:0097659 379 0.049
purine containing compound metabolic process GO:0072521 253 0.047
anatomical structure morphogenesis GO:0009653 298 0.047
positive regulation of catalytic activity GO:0043085 184 0.046
cognition GO:0050890 92 0.046
organophosphate biosynthetic process GO:0090407 143 0.046
regulation of glutamate receptor signaling pathway GO:1900449 17 0.046
positive regulation of gene expression GO:0010628 244 0.046
regulation of neurotransmitter levels GO:0001505 42 0.046
positive regulation of organelle organization GO:0010638 48 0.045
synaptic growth at neuromuscular junction GO:0051124 1 0.045
reproductive process GO:0022414 372 0.045
Worm
head development GO:0060322 247 0.045
dorsal ventral axon guidance GO:0033563 1 0.045
Worm
cgmp biosynthetic process GO:0006182 15 0.045
cellular response to oxygen containing compound GO:1901701 386 0.045
purine nucleotide metabolic process GO:0006163 229 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.045
endoplasmic reticulum membrane organization GO:0090158 1 0.044
macromolecular complex assembly GO:0065003 273 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.044
Worm
dephosphorylation GO:0016311 98 0.044
positive regulation of neuron projection development GO:0010976 99 0.044
Worm
protein complex biogenesis GO:0070271 263 0.043
peptide hormone secretion GO:0030072 84 0.043
calcium ion transport GO:0006816 131 0.043
single organism intracellular transport GO:1902582 166 0.043
regulation of ion transmembrane transport GO:0034765 121 0.043
cellular response to hormone stimulus GO:0032870 247 0.042
regulation of organelle organization GO:0033043 80 0.042
g protein coupled acetylcholine receptor signaling pathway GO:0007213 5 0.042
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.042
positive regulation of protein transport GO:0051222 41 0.041
neurotransmitter gated ion channel clustering GO:0072578 3 0.041
negative regulation of secretion GO:0051048 82 0.041
associative learning GO:0008306 19 0.041
purine ribonucleoside catabolic process GO:0046130 124 0.041
long term synaptic potentiation GO:0060291 21 0.040
regulation of phosphorylation GO:0042325 248 0.040
hormone secretion GO:0046879 115 0.040
negative regulation of cellular biosynthetic process GO:0031327 161 0.039
regulation of insulin secretion GO:0050796 65 0.039
regulation of protein modification process GO:0031399 194 0.039
positive regulation of ion transport GO:0043270 94 0.039
regulation of cell development GO:0060284 263 0.038
Worm
somatostatin receptor signaling pathway GO:0038169 4 0.038
regulation of protein phosphorylation GO:0001932 183 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
nucleoside triphosphate metabolic process GO:0009141 144 0.038
neuron projection development GO:0031175 273 0.038
response to peptide GO:1901652 292 0.038
positive regulation of cell development GO:0010720 176 0.037
Worm
cyclic purine nucleotide metabolic process GO:0052652 62 0.037
cellular calcium ion homeostasis GO:0006874 160 0.037
regulation of anatomical structure morphogenesis GO:0022603 141 0.037
Worm
cerebellar purkinje cell layer development GO:0021680 2 0.037
purine containing compound catabolic process GO:0072523 138 0.037
ribonucleoside catabolic process GO:0042454 126 0.037
ribonucleotide biosynthetic process GO:0009260 85 0.036
action potential GO:0001508 54 0.036
cyclic nucleotide metabolic process GO:0009187 80 0.036
homeostatic process GO:0042592 331 0.036
regulation of peptide hormone secretion GO:0090276 80 0.036
establishment of vesicle localization GO:0051650 31 0.036
regulation of calcium ion transport GO:0051924 77 0.036
carbohydrate derivative biosynthetic process GO:1901137 124 0.035
protein oligomerization GO:0051259 191 0.035
positive regulation of cyclase activity GO:0031281 15 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
negative regulation of calcium ion dependent exocytosis GO:0045955 5 0.034
nucleotide biosynthetic process GO:0009165 98 0.034
regulation of purine nucleotide metabolic process GO:1900542 115 0.034
l glutamate import GO:0051938 2 0.034
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.034
positive regulation of exocytosis GO:0045921 19 0.034
regulation of neuron differentiation GO:0045664 208 0.034
Worm
single organism organelle organization GO:1902589 180 0.034
cytosolic calcium ion homeostasis GO:0051480 140 0.034
cellular ion homeostasis GO:0006873 184 0.034
cellular response to growth factor stimulus GO:0071363 162 0.034
single organism reproductive process GO:0044702 297 0.033
Worm
locomotory exploration behavior GO:0035641 1 0.033
regulation of cyclase activity GO:0031279 21 0.033
positive regulation of intracellular signal transduction GO:1902533 138 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
regulation of nucleotide biosynthetic process GO:0030808 47 0.033
cellular component morphogenesis GO:0032989 155 0.033
response to mechanical stimulus GO:0009612 134 0.032
amide transport GO:0042886 105 0.032
gliogenesis GO:0042063 93 0.032
Fly
negative regulation of peptide hormone secretion GO:0090278 30 0.032
hormone transport GO:0009914 121 0.032
negative regulation of exocytosis GO:0045920 7 0.032
regulation of neurogenesis GO:0050767 247 0.032
Worm
positive regulation of secretion by cell GO:1903532 128 0.032
response to light stimulus GO:0009416 52 0.031
purine ribonucleotide metabolic process GO:0009150 227 0.031
response to glucocorticoid GO:0051384 223 0.031
cellular component movement GO:0006928 248 0.031
single organism membrane fusion GO:0044801 17 0.031
regulation of hormone secretion GO:0046883 106 0.031
regulation of growth GO:0040008 105 0.031
Worm
regulation of anatomical structure size GO:0090066 135 0.030
Worm
negative regulation of neuron apoptotic process GO:0043524 45 0.030
positive regulation of cell communication GO:0010647 271 0.030
Rat
cellular response to nitrogen compound GO:1901699 210 0.030
single organism biosynthetic process GO:0044711 342 0.030
regulation of kinase activity GO:0043549 117 0.030
chemosensory behavior GO:0007635 2 0.030
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
Worm
rna metabolic process GO:0016070 406 0.030
regulation of respiratory system process GO:0044065 1 0.030
regulation of lyase activity GO:0051339 22 0.029
regulation of long term neuronal synaptic plasticity GO:0048169 15 0.029
purine containing compound biosynthetic process GO:0072522 85 0.029
positive regulation of synaptic vesicle endocytosis GO:1900244 1 0.029
small gtpase mediated signal transduction GO:0007264 36 0.029
regulation of transferase activity GO:0051338 123 0.029
lipid modification GO:0030258 52 0.029
regulation of neuronal synaptic plasticity GO:0048168 31 0.028
axonogenesis GO:0007409 71 0.028
regulation of protein kinase activity GO:0045859 105 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.028
Worm
cellular metal ion homeostasis GO:0006875 172 0.028
cytoplasmic transport GO:0016482 115 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
purine nucleoside metabolic process GO:0042278 169 0.028
response to reactive oxygen species GO:0000302 120 0.028
phospholipid metabolic process GO:0006644 61 0.028
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.028
multicellular organism growth GO:0035264 1 0.028
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
olfactory behavior GO:0042048 2 0.027
regulation of developmental growth GO:0048638 45 0.027
Worm
regulation of inhibitory postsynaptic membrane potential GO:0060080 6 0.027
thigmotaxis GO:0001966 1 0.027
positive regulation of neuron differentiation GO:0045666 126 0.027
Worm
positive regulation of protein modification process GO:0031401 142 0.027
cellular amine metabolic process GO:0044106 38 0.027
vesicle localization GO:0051648 33 0.027
positive regulation of nucleoside metabolic process GO:0045979 55 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
cellular macromolecule localization GO:0070727 122 0.026
endocytosis GO:0006897 84 0.026
neuron apoptotic process GO:0051402 88 0.026
regulation of lipid metabolic process GO:0019216 68 0.026
rhythmic behavior GO:0007622 24 0.026
single organism carbohydrate metabolic process GO:0044723 118 0.026
n methyl d aspartate receptor clustering GO:0097114 2 0.026
tissue development GO:0009888 252 0.026
Worm
phospholipid dephosphorylation GO:0046839 5 0.026
potassium ion transmembrane transport GO:0071805 71 0.026
regulation of mapk cascade GO:0043408 116 0.025
hematopoietic progenitor cell differentiation GO:0002244 2 0.025
dna metabolic process GO:0006259 96 0.025
regulation of dendrite development GO:0050773 59 0.025
regulation of cell growth GO:0001558 85 0.025
Worm
cyclic nucleotide biosynthetic process GO:0009190 63 0.025
pallium development GO:0021543 42 0.025
negative regulation of molecular function GO:0044092 133 0.025
negative regulation of gene expression GO:0010629 199 0.025
regulation of transcription dna templated GO:0006355 374 0.025
gtp catabolic process GO:0006184 71 0.024
positive regulation of cell death GO:0010942 184 0.024
Rat
organonitrogen compound catabolic process GO:1901565 179 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
Worm
regulation of hormone levels GO:0010817 187 0.024
response to alkaloid GO:0043279 132 0.024
response to toxic substance GO:0009636 133 0.024
response to ethanol GO:0045471 162 0.024
cellular potassium ion transport GO:0071804 72 0.024
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.024
leukocyte differentiation GO:0002521 30 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.023
nucleobase containing compound catabolic process GO:0034655 152 0.023
positive regulation of hydrolase activity GO:0051345 86 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
glycosyl compound metabolic process GO:1901657 182 0.023
chemical homeostasis GO:0048878 292 0.023
regulation of nervous system development GO:0051960 264 0.023
Worm
regulation of purine nucleotide catabolic process GO:0033121 65 0.023
activation of phospholipase d activity GO:0031584 2 0.023
limbic system development GO:0021761 38 0.023
locomotion GO:0040011 237 0.023
axon midline choice point recognition GO:0016199 2 0.023
negative regulation of cellular component organization GO:0051129 83 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
protein autophosphorylation GO:0046777 66 0.022
nucleotide catabolic process GO:0009166 139 0.022
cell migration GO:0016477 197 0.022
Worm Fly
cellular cation homeostasis GO:0030003 180 0.022
glycosyl compound catabolic process GO:1901658 126 0.022
endoplasmic reticulum organization GO:0007029 1 0.022
positive regulation of adenylate cyclase activity GO:0045762 12 0.022
cation homeostasis GO:0055080 195 0.022
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.022
axon development GO:0061564 96 0.022
sodium ion transport GO:0006814 82 0.022
organ regeneration GO:0031100 101 0.022
aromatic compound catabolic process GO:0019439 168 0.022
salivary gland development GO:0007431 3 0.022
Fly
mesoderm development GO:0007498 2 0.022
Worm
regulation of cellular catabolic process GO:0031329 101 0.022
sensory organ development GO:0007423 74 0.022
regulation of cellular component movement GO:0051270 150 0.022
cellular response to insulin stimulus GO:0032869 81 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.021
circulatory system process GO:0003013 183 0.021
blood circulation GO:0008015 183 0.021
response to growth factor GO:0070848 189 0.021
carbohydrate homeostasis GO:0033500 75 0.021
cell cycle GO:0007049 101 0.021
camp biosynthetic process GO:0006171 47 0.021
muscle system process GO:0003012 115 0.021
positive regulation of transferase activity GO:0051347 81 0.021
response to metal ion GO:0010038 253 0.021
regulation of proteasomal protein catabolic process GO:0061136 4 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
cerebellar cortex formation GO:0021697 2 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
response to oxidative stress GO:0006979 186 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.020
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.020
regulation of nucleocytoplasmic transport GO:0046822 28 0.020
jak stat cascade GO:0007259 26 0.020
motor neuron axon guidance GO:0008045 1 0.020
Worm Fly
regulation of intracellular transport GO:0032386 65 0.020
cellular response to steroid hormone stimulus GO:0071383 93 0.020
nucleoside catabolic process GO:0009164 126 0.020
protein heterooligomerization GO:0051291 89 0.020
positive regulation of kinase activity GO:0033674 77 0.020
regulation of dendrite morphogenesis GO:0048814 33 0.020
rna biosynthetic process GO:0032774 380 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.019
regulation of hydrolase activity GO:0051336 143 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
positive regulation of gtp catabolic process GO:0033126 48 0.019
response to peptide hormone GO:0043434 278 0.019
neuron recognition GO:0008038 9 0.019
response to cytokine GO:0034097 215 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.019
detection of stimulus GO:0051606 24 0.019
response to ammonium ion GO:0060359 71 0.019
synapse assembly GO:0007416 29 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
positive regulation of protein kinase activity GO:0045860 73 0.019
sensory perception GO:0007600 101 0.019
cytokine mediated signaling pathway GO:0019221 43 0.019
carbohydrate derivative catabolic process GO:1901136 147 0.019
inner ear receptor cell differentiation GO:0060113 2 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
cell differentiation in hindbrain GO:0021533 2 0.019
positive regulation of growth GO:0045927 55 0.019
Worm
presynaptic membrane assembly GO:0097105 3 0.018
cellular response to oxygen levels GO:0071453 60 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
membrane depolarization GO:0051899 32 0.018
central nervous system neuron differentiation GO:0021953 17 0.018
transcription dna templated GO:0006351 377 0.018
regulation of endocytosis GO:0030100 42 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.018
gtp metabolic process GO:0046039 72 0.018
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
regulation of transmembrane transport GO:0034762 122 0.018
regeneration GO:0031099 163 0.018
heterocycle catabolic process GO:0046700 167 0.018
cellular chemical homeostasis GO:0055082 247 0.018
regulation of vesicle fusion GO:0031338 6 0.018
learning or memory GO:0007611 90 0.018
purine nucleoside catabolic process GO:0006152 124 0.017
hexose metabolic process GO:0019318 58 0.017
hippocampus development GO:0021766 30 0.017
dendrite development GO:0016358 72 0.017
Worm
camp metabolic process GO:0046058 63 0.017
cellular response to external stimulus GO:0071496 118 0.017
regulation of gtpase activity GO:0043087 57 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
enzyme linked receptor protein signaling pathway GO:0007167 116 0.017
lipid metabolic process GO:0006629 283 0.017
negative regulation of phosphorus metabolic process GO:0010563 80 0.017
mechanoreceptor differentiation GO:0042490 2 0.017
regulation of neurotransmitter transport GO:0051588 21 0.017
response to amine GO:0014075 46 0.017
signal transduction by phosphorylation GO:0023014 144 0.017

Unc5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.043
disease of cellular proliferation DOID:14566 0 0.043
organ system cancer DOID:0050686 0 0.043
inherited metabolic disorder DOID:655 0 0.025
carbohydrate metabolic disorder DOID:2978 0 0.025
disease of metabolism DOID:0014667 0 0.025
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020