Rattus norvegicus

0 known processes

Unc5cl

unc-5 homolog C (C. elegans)-like

Unc5cl biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.200
rna biosynthetic process GO:0032774 380 0.136
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.097
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.095
nucleic acid templated transcription GO:0097659 379 0.089
regulation of nucleic acid templated transcription GO:1903506 380 0.085
tissue development GO:0009888 252 0.082
regulation of rna metabolic process GO:0051252 391 0.076
regulation of rna biosynthetic process GO:2001141 381 0.075
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.074
positive regulation of cell proliferation GO:0008284 249 0.073
regulation of programmed cell death GO:0043067 341 0.066
negative regulation of macromolecule metabolic process GO:0010605 260 0.066
regulation of cell differentiation GO:0045595 320 0.066
rna metabolic process GO:0016070 406 0.066
positive regulation of rna metabolic process GO:0051254 203 0.065
response to retinoic acid GO:0032526 63 0.064
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.060
regulation of cell development GO:0060284 263 0.055
positive regulation of transcription dna templated GO:0045893 197 0.055
positive regulation of rna biosynthetic process GO:1902680 197 0.054
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.052
positive regulation of gene expression GO:0010628 244 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.048
homeostatic process GO:0042592 331 0.047
programmed cell death GO:0012501 392 0.047
positive regulation of biosynthetic process GO:0009891 319 0.047
negative regulation of cellular biosynthetic process GO:0031327 161 0.044
transcription from rna polymerase ii promoter GO:0006366 252 0.042
catabolic process GO:0009056 351 0.041
response to oxidative stress GO:0006979 186 0.040
transcription dna templated GO:0006351 377 0.040
positive regulation of nucleic acid templated transcription GO:1903508 197 0.039
positive regulation of phosphorus metabolic process GO:0010562 262 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.037
positive regulation of cell differentiation GO:0045597 217 0.037
response to external biotic stimulus GO:0043207 221 0.037
organic acid metabolic process GO:0006082 292 0.037
sterol homeostasis GO:0055092 3 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.035
apoptotic process GO:0006915 381 0.034
positive regulation of programmed cell death GO:0043068 157 0.034
behavior GO:0007610 205 0.033
negative regulation of nucleic acid templated transcription GO:1903507 117 0.033
defense response GO:0006952 194 0.032
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.032
single organism reproductive process GO:0044702 297 0.032
immune response to tumor cell GO:0002418 3 0.032
macromolecular complex assembly GO:0065003 273 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.030
regulation of cell proliferation GO:0042127 359 0.030
negative regulation of metabolic process GO:0009892 331 0.030
regulation of apoptotic process GO:0042981 335 0.030
chemical homeostasis GO:0048878 292 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
cellular response to oxygen containing compound GO:1901701 386 0.029
intracellular transport GO:0046907 185 0.029
cholesterol homeostasis GO:0042632 3 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
cellular response to endogenous stimulus GO:0071495 377 0.029
multicellular organismal reproductive process GO:0048609 233 0.028
organic substance catabolic process GO:1901575 316 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.027
cofactor metabolic process GO:0051186 95 0.027
epithelium development GO:0060429 96 0.027
response to nutrient levels GO:0031667 370 0.027
brain development GO:0007420 247 0.026
response to hydrogen peroxide GO:0042542 89 0.026
multi multicellular organism process GO:0044706 138 0.026
protein complex assembly GO:0006461 263 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
positive regulation of apoptotic process GO:0043065 154 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
reproduction GO:0000003 245 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.023
multicellular organism reproduction GO:0032504 233 0.023
regulation of immune system process GO:0002682 123 0.023
negative regulation of rna biosynthetic process GO:1902679 118 0.023
embryonic axis specification GO:0000578 1 0.023
regulation of signal transduction GO:0009966 318 0.023
neuron differentiation GO:0030182 368 0.023
protein complex subunit organization GO:0071822 302 0.022
axis specification GO:0009798 4 0.022
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.022
skeletal system development GO:0001501 41 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
regulation of response to stress GO:0080134 126 0.022
regulation of nervous system development GO:0051960 264 0.022
negative regulation of developmental process GO:0051093 125 0.021
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.021
immune response GO:0006955 104 0.021
ras protein signal transduction GO:0007265 29 0.021
cellular response to stress GO:0033554 269 0.021
cellular ketone metabolic process GO:0042180 51 0.021
positive regulation of nervous system development GO:0051962 178 0.021
response to reactive oxygen species GO:0000302 120 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
sensory organ development GO:0007423 74 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
negative regulation of transcription dna templated GO:0045892 116 0.020
cellular amine metabolic process GO:0044106 38 0.020
cell projection organization GO:0030030 302 0.020
positive regulation of developmental process GO:0051094 283 0.020
carboxylic acid metabolic process GO:0019752 289 0.019
response to molecule of fungal origin GO:0002238 3 0.019
protein localization GO:0008104 191 0.019
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.019
glutamate receptor signaling pathway GO:0007215 43 0.019
negative regulation of molecular function GO:0044092 133 0.018
central nervous system development GO:0007417 311 0.018
regulation of neuron projection development GO:0010975 161 0.018
embryonic pattern specification GO:0009880 1 0.018
organ morphogenesis GO:0009887 75 0.018
pyridine nucleotide biosynthetic process GO:0019363 2 0.018
epithelial cell differentiation GO:0030855 71 0.018
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
macromolecule localization GO:0033036 252 0.018
cellular catabolic process GO:0044248 295 0.018
lipid storage GO:0019915 1 0.018
response to organophosphorus GO:0046683 102 0.018
cellular component assembly GO:0022607 360 0.017
establishment of protein localization GO:0045184 141 0.017
negative regulation of cell development GO:0010721 82 0.017
immune system process GO:0002376 204 0.017
cation transmembrane transport GO:0098655 263 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
calcium ion homeostasis GO:0055074 162 0.017
proteolysis GO:0006508 175 0.017
single organism intracellular transport GO:1902582 166 0.017
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.017
protein phosphorylation GO:0006468 345 0.017
embryonic limb morphogenesis GO:0030326 4 0.017
negative regulation of response to tumor cell GO:0002835 2 0.016
regulation of response to wounding GO:1903034 69 0.016
sulfur compound metabolic process GO:0006790 70 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
mesoderm morphogenesis GO:0048332 1 0.016
cell adhesion GO:0007155 110 0.016
bmp signaling pathway GO:0030509 4 0.016
single organism catabolic process GO:0044712 283 0.016
anterior posterior pattern specification GO:0009952 1 0.016
response to wounding GO:0009611 254 0.016
intracellular signal transduction GO:0035556 314 0.016
circadian rhythm GO:0007623 88 0.016
protein transport GO:0015031 132 0.015
response to biotic stimulus GO:0009607 226 0.015
locomotion GO:0040011 237 0.015
positive regulation of gastric acid secretion GO:0060454 2 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
gamete generation GO:0007276 124 0.015
response to purine containing compound GO:0014074 126 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
single organism behavior GO:0044708 130 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
response to metformin GO:1901558 1 0.015
regulation of cell projection organization GO:0031344 175 0.015
kidney development GO:0001822 67 0.015
negative regulation of neurogenesis GO:0050768 78 0.014
regulation of phosphorylation GO:0042325 248 0.014
nucleotide metabolic process GO:0009117 279 0.014
response to bacterium GO:0009617 200 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
regulation of immune response GO:0050776 55 0.014
positive regulation of cell development GO:0010720 176 0.014
response to inorganic substance GO:0010035 377 0.014
positive regulation of signal transduction GO:0009967 175 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
membrane organization GO:0061024 94 0.014
cellular chemical homeostasis GO:0055082 247 0.014
negative regulation of cell death GO:0060548 229 0.014
regulation of response to tumor cell GO:0002834 3 0.014
positive regulation of cell death GO:0010942 184 0.014
tongue morphogenesis GO:0043587 3 0.013
negative regulation of immune response to tumor cell GO:0002838 2 0.013
negative regulation of gene expression GO:0010629 199 0.013
vitamin d receptor signaling pathway GO:0070561 1 0.013
cardiac chamber development GO:0003205 1 0.013
adult locomotory behavior GO:0008344 4 0.013
response to tumor cell GO:0002347 4 0.013
cellular response to retinoic acid GO:0071300 27 0.013
regulation of molecular function GO:0065009 398 0.013
reproductive process GO:0022414 372 0.013
response to acid chemical GO:0001101 222 0.013
neuron death GO:0070997 127 0.013
response to growth factor GO:0070848 189 0.013
response to cytokine GO:0034097 215 0.013
mesoderm development GO:0007498 2 0.013
camera type eye development GO:0043010 48 0.013
renal system development GO:0072001 67 0.013
cellular response to acid chemical GO:0071229 75 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
eye morphogenesis GO:0048592 4 0.013
anion transport GO:0006820 178 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
heart morphogenesis GO:0003007 3 0.013
endocytosis GO:0006897 84 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
cell morphogenesis GO:0000902 142 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
positive regulation of signaling GO:0023056 270 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
cellular ion homeostasis GO:0006873 184 0.012
negative regulation of response to biotic stimulus GO:0002832 4 0.012
oxoacid metabolic process GO:0043436 290 0.012
female pregnancy GO:0007565 122 0.012
cation transport GO:0006812 382 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
regulation of cell motility GO:2000145 131 0.012
nicotinamide nucleotide biosynthetic process GO:0019359 2 0.012
circulatory system development GO:0072359 134 0.012
camera type eye morphogenesis GO:0048593 2 0.012
protein oligomerization GO:0051259 191 0.012
cellular homeostasis GO:0019725 252 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
transmembrane transport GO:0055085 412 0.012
ribose phosphate metabolic process GO:0019693 235 0.011
choline transport GO:0015871 4 0.011
negative regulation of synaptic transmission dopaminergic GO:0032227 4 0.011
negative regulation of cell communication GO:0010648 158 0.011
neuron projection development GO:0031175 273 0.011
response to ethanol GO:0045471 162 0.011
heart development GO:0007507 72 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
spermatogenesis GO:0007283 99 0.011
multi organism reproductive process GO:0044703 262 0.011
cardiac ventricle development GO:0003231 1 0.011
organic anion transport GO:0015711 132 0.011
response to starvation GO:0042594 59 0.011
leukocyte cell cell adhesion GO:0007159 4 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
aromatic compound catabolic process GO:0019439 168 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
response to extracellular stimulus GO:0009991 380 0.011
rna localization GO:0006403 4 0.011
sexual reproduction GO:0019953 148 0.011
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.011
cardiovascular system development GO:0072358 134 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
developmental growth GO:0048589 100 0.011
ion homeostasis GO:0050801 212 0.011
regulation of membrane potential GO:0042391 110 0.011
nitrogen compound transport GO:0071705 229 0.011
response to temperature stimulus GO:0009266 94 0.011
ion transmembrane transport GO:0034220 365 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
positive regulation of phagocytosis engulfment GO:0060100 4 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
regulation of phagocytosis engulfment GO:0060099 4 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
amine metabolic process GO:0009308 38 0.010
positive regulation of transport GO:0051050 245 0.010
embryo development GO:0009790 49 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
response to monosaccharide GO:0034284 159 0.010
negative regulation of viral process GO:0048525 4 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
response to zinc ion GO:0010043 39 0.010
regulation of protein metabolic process GO:0051246 289 0.010

Unc5cl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
usher syndrome DOID:0050439 0 0.022
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.011
bone development disease DOID:0080006 0 0.011
bone disease DOID:0080001 0 0.011
osteochondrodysplasia DOID:2256 0 0.011
connective tissue disease DOID:65 0 0.011
disease of cellular proliferation DOID:14566 0 0.010