Rattus norvegicus

0 known processes

Usp18

ubiquitin specific peptidase 18

Usp18 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral genome replication GO:0045071 1 0.783
response to cytokine GO:0034097 215 0.447
negative regulation of viral process GO:0048525 4 0.353
viral genome replication GO:0019079 2 0.325
response to virus GO:0009615 17 0.323
jak stat cascade GO:0007259 26 0.289
cellular response to cytokine stimulus GO:0071345 127 0.274
response to biotic stimulus GO:0009607 226 0.267
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.245
response to external biotic stimulus GO:0043207 221 0.187
immune response GO:0006955 104 0.161
response to other organism GO:0051707 220 0.140
response to exogenous dsrna GO:0043330 3 0.134
response to estrogen GO:0043627 232 0.133
organophosphate metabolic process GO:0019637 370 0.105
nucleotide metabolic process GO:0009117 279 0.105
cellular response to peptide hormone stimulus GO:0071375 120 0.092
negative regulation of kidney development GO:0090185 2 0.089
regulation of phosphorus metabolic process GO:0051174 349 0.075
amine metabolic process GO:0009308 38 0.075
nucleoside phosphate metabolic process GO:0006753 283 0.074
reproductive process GO:0022414 372 0.067
purine containing compound biosynthetic process GO:0072522 85 0.066
regulation of rna metabolic process GO:0051252 391 0.058
carboxylic acid metabolic process GO:0019752 289 0.056
tolerance induction to nonself antigen GO:0002462 2 0.055
rna metabolic process GO:0016070 406 0.052
response to ethanol GO:0045471 162 0.051
regulation of protein metabolic process GO:0051246 289 0.047
purine nucleotide metabolic process GO:0006163 229 0.047
response to nutrient levels GO:0031667 370 0.047
organonitrogen compound biosynthetic process GO:1901566 167 0.047
purine containing compound metabolic process GO:0072521 253 0.046
transcription dna templated GO:0006351 377 0.046
metal ion homeostasis GO:0055065 186 0.045
regulation of purine nucleotide metabolic process GO:1900542 115 0.045
cellular response to oxygen containing compound GO:1901701 386 0.045
transcription from rna polymerase ii promoter GO:0006366 252 0.044
response to dsrna GO:0043331 9 0.043
regulation of cellular amine metabolic process GO:0033238 8 0.042
g protein coupled receptor signaling pathway GO:0007186 242 0.041
cellular response to peptide GO:1901653 133 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.040
cellular ketone metabolic process GO:0042180 51 0.039
positive regulation of multicellular organismal process GO:0051240 387 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
response to peptide hormone GO:0043434 278 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
negative regulation of jak stat cascade GO:0046426 3 0.037
positive regulation of t cell migration GO:2000406 1 0.037
organic acid metabolic process GO:0006082 292 0.036
metal ion transport GO:0030001 289 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
regulation of rna biosynthetic process GO:2001141 381 0.034
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.034
single organism biosynthetic process GO:0044711 342 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.033
regulation of t cell migration GO:2000404 1 0.032
cellular amine metabolic process GO:0044106 38 0.032
multi organism reproductive process GO:0044703 262 0.032
negative regulation of cell death GO:0060548 229 0.031
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
cellular response to hormone stimulus GO:0032870 247 0.030
positive regulation of cellular amine metabolic process GO:0033240 3 0.030
positive regulation of rna metabolic process GO:0051254 203 0.030
metanephric nephron tubule epithelial cell differentiation GO:0072257 1 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
nucleic acid templated transcription GO:0097659 379 0.029
positive regulation of transport GO:0051050 245 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
protein complex subunit organization GO:0071822 302 0.028
response to extracellular stimulus GO:0009991 380 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
ion homeostasis GO:0050801 212 0.028
regulation of viral genome replication GO:0045069 2 0.027
response to vitamin GO:0033273 131 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.026
organophosphate biosynthetic process GO:0090407 143 0.026
rna biosynthetic process GO:0032774 380 0.026
negative regulation of metanephros development GO:0072217 2 0.025
response to interferon beta GO:0035456 1 0.025
secretion GO:0046903 307 0.025
response to estradiol GO:0032355 164 0.024
nucleoside phosphate biosynthetic process GO:1901293 102 0.024
response to growth factor GO:0070848 189 0.024
regulation of tolerance induction to nonself antigen GO:0002655 1 0.023
response to mechanical stimulus GO:0009612 134 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
nucleotide biosynthetic process GO:0009165 98 0.023
negative regulation of response to stimulus GO:0048585 155 0.022
intracellular signal transduction GO:0035556 314 0.022
response to tumor necrosis factor GO:0034612 56 0.022
regulation of transcription dna templated GO:0006355 374 0.022
blood circulation GO:0008015 183 0.021
circulatory system process GO:0003013 183 0.021
epithelial cell differentiation involved in kidney development GO:0035850 3 0.021
regulation of lymphocyte migration GO:2000401 1 0.021
carbohydrate metabolic process GO:0005975 130 0.021
cation homeostasis GO:0055080 195 0.021
protein phosphorylation GO:0006468 345 0.021
purine nucleotide biosynthetic process GO:0006164 83 0.020
myeloid leukocyte migration GO:0097529 20 0.020
membrane organization GO:0061024 94 0.020
reproduction GO:0000003 245 0.020
peptide transport GO:0015833 97 0.020
negative regulation of tyrosine phosphorylation of stat1 protein GO:0042512 1 0.020
cellular response to external stimulus GO:0071496 118 0.019
cation transport GO:0006812 382 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
negative regulation of signaling GO:0023057 157 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
regulation of apoptotic process GO:0042981 335 0.019
macromolecule localization GO:0033036 252 0.018
chemical homeostasis GO:0048878 292 0.018
maintenance of location GO:0051235 17 0.018
cellular response to tumor necrosis factor GO:0071356 46 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
negative regulation of innate immune response GO:0045824 4 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
neuron development GO:0048666 286 0.017
response to peptide GO:1901652 292 0.017
homeostatic process GO:0042592 331 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
positive regulation of lymphocyte migration GO:2000403 1 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
negative regulation of cell communication GO:0010648 158 0.016
protein localization GO:0008104 191 0.016
cellular response to nutrient levels GO:0031669 60 0.016
calcium ion homeostasis GO:0055074 162 0.016
regulation of cell proliferation GO:0042127 359 0.016
protein transport GO:0015031 132 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
multi multicellular organism process GO:0044706 138 0.016
regulation of programmed cell death GO:0043067 341 0.016
ribose phosphate metabolic process GO:0019693 235 0.015
cellular response to molecule of bacterial origin GO:0071219 56 0.015
cellular component assembly GO:0022607 360 0.015
negative regulation of protein phosphorylation GO:0001933 44 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
t cell chemotaxis GO:0010818 2 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
single organism reproductive process GO:0044702 297 0.015
response to acid chemical GO:0001101 222 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
oxoacid metabolic process GO:0043436 290 0.014
intracellular transport GO:0046907 185 0.014
regulation of cell development GO:0060284 263 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
regulation of response to stress GO:0080134 126 0.014
cellular homeostasis GO:0019725 252 0.014
regulation of hormone levels GO:0010817 187 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
establishment of protein localization GO:0045184 141 0.014
mesenchymal cell differentiation involved in renal system development GO:2001012 1 0.013
liver development GO:0001889 90 0.013
negative regulation of protein modification process GO:0031400 52 0.013
neuron projection development GO:0031175 273 0.013
response to interleukin 1 GO:0070555 55 0.013
multicellular organism reproduction GO:0032504 233 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
regulation of metanephros development GO:0072215 4 0.013
positive regulation of mast cell chemotaxis GO:0060754 1 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
regulation of camp metabolic process GO:0030814 43 0.013
cellular cation homeostasis GO:0030003 180 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
response to oxygen levels GO:0070482 265 0.013
brain development GO:0007420 247 0.012
single organism intracellular transport GO:1902582 166 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
negative regulation of hydrogen peroxide metabolic process GO:0010727 2 0.012
calcium ion transport GO:0006816 131 0.012
cellular chemical homeostasis GO:0055082 247 0.012
divalent inorganic cation transport GO:0072511 134 0.012
regulation of protein transport GO:0051223 68 0.012
positive regulation of tolerance induction to nonself antigen GO:0002657 1 0.012
cellular response to lipid GO:0071396 201 0.012
macromolecular complex assembly GO:0065003 273 0.012
regulation of catalytic activity GO:0050790 304 0.012
secretion by cell GO:0032940 248 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
regulation of membrane potential GO:0042391 110 0.012
negative regulation of programmed cell death GO:0043069 183 0.011
neuron differentiation GO:0030182 368 0.011
negative regulation of metabolic process GO:0009892 331 0.011
kidney mesenchyme development GO:0072074 2 0.011
neurological system process GO:0050877 219 0.011
negative regulation of cell projection organization GO:0031345 50 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
cell cell signaling GO:0007267 335 0.011
regulation of cell differentiation GO:0045595 320 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
response to starvation GO:0042594 59 0.011
regulation of neuron projection development GO:0010975 161 0.011
response to hypoxia GO:0001666 231 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
regulation of cellular localization GO:0060341 263 0.010
cellular response to stress GO:0033554 269 0.010
negative regulation of signal transduction GO:0009968 83 0.010

Usp18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
urinary system disease DOID:18 0 0.026
disease of anatomical entity DOID:7 0 0.026
sensory system disease DOID:0050155 0 0.012
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.010