Rattus norvegicus

0 known processes

Usp25

ubiquitin specific peptidase 25

Usp25 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organelle organization GO:0006996 266 0.180
regulation of phosphorus metabolic process GO:0051174 349 0.167
secretion GO:0046903 307 0.160
tissue development GO:0009888 252 0.144
intracellular signal transduction GO:0035556 314 0.126
positive regulation of biosynthetic process GO:0009891 319 0.119
macromolecular complex subunit organization GO:0043933 339 0.113
regulation of phosphorylation GO:0042325 248 0.108
multi organism reproductive process GO:0044703 262 0.103
reproductive process GO:0022414 372 0.101
negative regulation of metabolic process GO:0009892 331 0.099
amide transport GO:0042886 105 0.096
negative regulation of cell death GO:0060548 229 0.086
multicellular organism reproduction GO:0032504 233 0.085
cytoskeleton organization GO:0007010 111 0.082
single organism reproductive process GO:0044702 297 0.082
regulation of rna metabolic process GO:0051252 391 0.080
response to estrogen GO:0043627 232 0.079
regulation of intracellular signal transduction GO:1902531 218 0.072
positive regulation of cell proliferation GO:0008284 249 0.069
secretion by cell GO:0032940 248 0.068
positive regulation of response to stimulus GO:0048584 285 0.067
positive regulation of phosphorus metabolic process GO:0010562 262 0.066
protein complex subunit organization GO:0071822 302 0.066
single organism organelle organization GO:1902589 180 0.065
regulation of signal transduction GO:0009966 318 0.064
actin cytoskeleton organization GO:0030036 73 0.063
negative regulation of cellular metabolic process GO:0031324 281 0.062
positive regulation of cellular biosynthetic process GO:0031328 295 0.060
regulation of ossification GO:0030278 32 0.060
negative regulation of biosynthetic process GO:0009890 168 0.058
aging GO:0007568 241 0.057
transcription dna templated GO:0006351 377 0.057
cation transport GO:0006812 382 0.057
regulation of cellular protein metabolic process GO:0032268 267 0.055
protein phosphorylation GO:0006468 345 0.055
organonitrogen compound biosynthetic process GO:1901566 167 0.055
positive regulation of developmental process GO:0051094 283 0.054
anatomical structure morphogenesis GO:0009653 298 0.053
regulation of peptide transport GO:0090087 87 0.053
positive regulation of protein modification process GO:0031401 142 0.052
macromolecule localization GO:0033036 252 0.052
response to growth factor GO:0070848 189 0.050
regulation of secretion GO:0051046 224 0.049
signal transduction by phosphorylation GO:0023014 144 0.047
carbohydrate derivative metabolic process GO:1901135 346 0.046
neurological system process GO:0050877 219 0.045
camp metabolic process GO:0046058 63 0.045
apoptotic process GO:0006915 381 0.045
cellular component assembly GO:0022607 360 0.045
regulation of cellular localization GO:0060341 263 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.043
metal ion transport GO:0030001 289 0.043
cellular metal ion homeostasis GO:0006875 172 0.043
carbohydrate derivative biosynthetic process GO:1901137 124 0.042
cellular ion homeostasis GO:0006873 184 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
protein complex assembly GO:0006461 263 0.041
response to peptide GO:1901652 292 0.041
mapk cascade GO:0000165 140 0.039
regulation of protein metabolic process GO:0051246 289 0.039
peptide secretion GO:0002790 86 0.039
regulation of response to stress GO:0080134 126 0.039
cellular response to stress GO:0033554 269 0.039
positive regulation of cellular component organization GO:0051130 200 0.038
protein complex biogenesis GO:0070271 263 0.038
regulation of nucleic acid templated transcription GO:1903506 380 0.038
nucleic acid templated transcription GO:0097659 379 0.037
transcription from rna polymerase ii promoter GO:0006366 252 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.036
negative regulation of transport GO:0051051 136 0.036
single organism biosynthetic process GO:0044711 342 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
cellular response to oxygen containing compound GO:1901701 386 0.036
homeostatic process GO:0042592 331 0.035
cellular chemical homeostasis GO:0055082 247 0.035
blood circulation GO:0008015 183 0.035
immune system process GO:0002376 204 0.035
negative regulation of apoptotic process GO:0043066 181 0.034
signal release GO:0023061 145 0.034
regulation of peptide hormone secretion GO:0090276 80 0.034
positive regulation of phosphorylation GO:0042327 177 0.034
positive regulation of bone mineralization GO:0030501 4 0.034
positive regulation of transcription dna templated GO:0045893 197 0.033
cellular homeostasis GO:0019725 252 0.033
response to decreased oxygen levels GO:0036293 237 0.033
neuron development GO:0048666 286 0.033
cation homeostasis GO:0055080 195 0.033
vitamin d receptor signaling pathway GO:0070561 1 0.033
divalent inorganic cation homeostasis GO:0072507 165 0.032
multi multicellular organism process GO:0044706 138 0.032
response to cytokine GO:0034097 215 0.032
programmed cell death GO:0012501 392 0.032
protein oligomerization GO:0051259 191 0.031
macromolecular complex assembly GO:0065003 273 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
cellular response to growth factor stimulus GO:0071363 162 0.031
chemical homeostasis GO:0048878 292 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
negative regulation of programmed cell death GO:0043069 183 0.031
anterior posterior pattern specification GO:0009952 1 0.031
hormone secretion GO:0046879 115 0.031
response to oxygen levels GO:0070482 265 0.031
regulation of secretion by cell GO:1903530 208 0.031
hormone transport GO:0009914 121 0.030
response to inorganic substance GO:0010035 377 0.030
peptide hormone secretion GO:0030072 84 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
nitrogen compound transport GO:0071705 229 0.030
peptide transport GO:0015833 97 0.030
response to heat GO:0009408 60 0.029
catabolic process GO:0009056 351 0.029
negative regulation of secretion GO:0051048 82 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
cellular response to platelet derived growth factor stimulus GO:0036120 7 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
rna biosynthetic process GO:0032774 380 0.028
reproduction GO:0000003 245 0.028
positive regulation of signaling GO:0023056 270 0.028
regulation of apoptotic process GO:0042981 335 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
cell cycle GO:0007049 101 0.028
stress activated mapk cascade GO:0051403 35 0.028
neuron differentiation GO:0030182 368 0.027
cellular response to cytokine stimulus GO:0071345 127 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
protein localization GO:0008104 191 0.027
regulation of programmed cell death GO:0043067 341 0.027
sexual reproduction GO:0019953 148 0.027
response to reactive oxygen species GO:0000302 120 0.026
central nervous system development GO:0007417 311 0.026
g protein coupled receptor signaling pathway GO:0007186 242 0.025
cell projection organization GO:0030030 302 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.025
positive regulation of transport GO:0051050 245 0.025
negative regulation of cell communication GO:0010648 158 0.025
regulation of cell proliferation GO:0042127 359 0.025
ion homeostasis GO:0050801 212 0.024
negative regulation of secretion by cell GO:1903531 72 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
response to metal ion GO:0010038 253 0.024
localization of cell GO:0051674 202 0.024
regulation of peptide secretion GO:0002791 82 0.024
regulation of response to external stimulus GO:0032101 106 0.024
regulation of immune system process GO:0002682 123 0.024
protein transport GO:0015031 132 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
oxoacid metabolic process GO:0043436 290 0.023
cellular response to lipid GO:0071396 201 0.023
single organism intracellular transport GO:1902582 166 0.023
regulation of protein modification process GO:0031399 194 0.023
regulation of hormone secretion GO:0046883 106 0.023
response to hypoxia GO:0001666 231 0.023
cytosolic calcium ion homeostasis GO:0051480 140 0.023
calcium ion homeostasis GO:0055074 162 0.023
regulation of stress activated mapk cascade GO:0032872 23 0.023
cellular component movement GO:0006928 248 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
positive regulation of mapk cascade GO:0043410 92 0.022
positive regulation of biomineral tissue development GO:0070169 4 0.022
response to oxidative stress GO:0006979 186 0.022
response to ammonium ion GO:0060359 71 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
regulation of cell development GO:0060284 263 0.022
oxidation reduction process GO:0055114 304 0.022
response to mechanical stimulus GO:0009612 134 0.022
establishment of protein localization GO:0045184 141 0.022
regulation of homeostatic process GO:0032844 101 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
sensory perception GO:0007600 101 0.021
organophosphate metabolic process GO:0019637 370 0.021
cellular cation homeostasis GO:0030003 180 0.021
cellular catabolic process GO:0044248 295 0.021
cellular component biogenesis GO:0044085 368 0.021
response to radiation GO:0009314 137 0.021
cytokine biosynthetic process GO:0042089 3 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
cellular protein localization GO:0034613 122 0.021
neuron projection development GO:0031175 273 0.021
amino acid transport GO:0006865 70 0.020
response to transforming growth factor beta GO:0071559 46 0.020
cell cycle process GO:0022402 57 0.020
regulation of molecular function GO:0065009 398 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
amine metabolic process GO:0009308 38 0.020
cyclic nucleotide metabolic process GO:0009187 80 0.020
defense response GO:0006952 194 0.020
regulation of nervous system development GO:0051960 264 0.020
response to peptide hormone GO:0043434 278 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
ras protein signal transduction GO:0007265 29 0.020
regulation of neuron death GO:1901214 115 0.020
regulation of neurogenesis GO:0050767 247 0.020
regulation of behavior GO:0050795 61 0.020
head development GO:0060322 247 0.020
regulation of cell differentiation GO:0045595 320 0.020
eye morphogenesis GO:0048592 4 0.020
cellular ketone metabolic process GO:0042180 51 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.019
maintenance of location GO:0051235 17 0.019
cell motility GO:0048870 202 0.019
protein homooligomerization GO:0051260 91 0.019
response to wounding GO:0009611 254 0.019
cellular amine metabolic process GO:0044106 38 0.019
stress activated protein kinase signaling cascade GO:0031098 37 0.019
ribonucleotide metabolic process GO:0009259 231 0.018
mesoderm development GO:0007498 2 0.018
rna metabolic process GO:0016070 406 0.018
gamete generation GO:0007276 124 0.018
negative regulation of hormone secretion GO:0046888 46 0.018
ribose phosphate biosynthetic process GO:0046390 87 0.018
response to external biotic stimulus GO:0043207 221 0.018
cellular component morphogenesis GO:0032989 155 0.018
negative regulation of gene expression GO:0010629 199 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
cell type specific apoptotic process GO:0097285 134 0.018
positive regulation of chemotaxis GO:0050921 23 0.017
gastrulation GO:0007369 2 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
epithelial cell differentiation GO:0030855 71 0.017
protein heterooligomerization GO:0051291 89 0.017
kidney development GO:0001822 67 0.017
intracellular transport GO:0046907 185 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
cytoplasmic transport GO:0016482 115 0.017
positive regulation of cytoplasmic transport GO:1903651 32 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
regulation of mapk cascade GO:0043408 116 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
learning or memory GO:0007611 90 0.017
negative regulation of signal transduction GO:0009968 83 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
metal ion homeostasis GO:0055065 186 0.016
epithelium development GO:0060429 96 0.016
cyclic purine nucleotide metabolic process GO:0052652 62 0.016
locomotion GO:0040011 237 0.016
regulation of hormone levels GO:0010817 187 0.016
positive regulation of signal transduction GO:0009967 175 0.016
transmembrane transport GO:0055085 412 0.016
positive regulation of locomotion GO:0040017 102 0.016
organic hydroxy compound metabolic process GO:1901615 115 0.016
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.016
response to biotic stimulus GO:0009607 226 0.016
positive regulation of cell development GO:0010720 176 0.016
regulation of intracellular transport GO:0032386 65 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
response to ketone GO:1901654 182 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
regulation of organelle organization GO:0033043 80 0.015
carboxylic acid metabolic process GO:0019752 289 0.015
single organism behavior GO:0044708 130 0.015
regulation of camp biosynthetic process GO:0030817 38 0.015
negative regulation of peptide hormone secretion GO:0090278 30 0.015
regulation of insulin secretion GO:0050796 65 0.015
negative regulation of signaling GO:0023057 157 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
response to acid chemical GO:0001101 222 0.015
cellular macromolecule localization GO:0070727 122 0.015
sequestering of metal ion GO:0051238 9 0.015
regeneration GO:0031099 163 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
brain development GO:0007420 247 0.015
jnk cascade GO:0007254 28 0.015
regulation of neuron differentiation GO:0045664 208 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.014
carbohydrate metabolic process GO:0005975 130 0.014
positive regulation of gene expression GO:0010628 244 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
organ morphogenesis GO:0009887 75 0.014
tube development GO:0035295 89 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
regulation of cellular component organization GO:0051128 368 0.014
inflammatory response GO:0006954 150 0.014
organic acid metabolic process GO:0006082 292 0.014
regulation of cell motility GO:2000145 131 0.014
insulin secretion GO:0030073 69 0.014
regulation of transcription dna templated GO:0006355 374 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
regulation of membrane potential GO:0042391 110 0.014
cellular response to molecule of bacterial origin GO:0071219 56 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
cell migration GO:0016477 197 0.013
regulation of calcium ion transport GO:0051924 77 0.013
circulatory system process GO:0003013 183 0.013
neuron death GO:0070997 127 0.013
nucleotide metabolic process GO:0009117 279 0.013
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.013
developmental growth GO:0048589 100 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
positive regulation of organelle organization GO:0010638 48 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
regulation of blood pressure GO:0008217 83 0.012
response to nutrient levels GO:0031667 370 0.012
positive regulation of response to external stimulus GO:0032103 51 0.012
response to monosaccharide GO:0034284 159 0.012
limbic system development GO:0021761 38 0.012
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.012
regulation of odontogenesis GO:0042481 4 0.012
organic substance catabolic process GO:1901575 316 0.012
positive regulation of calcium ion transport GO:0051928 36 0.012
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.012
regulation of ion transport GO:0043269 245 0.012
protein localization to organelle GO:0033365 57 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
positive regulation of saliva secretion GO:0046878 3 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
hexose metabolic process GO:0019318 58 0.012
endomembrane system organization GO:0010256 48 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
negative regulation of cell proliferation GO:0008285 119 0.011
female pregnancy GO:0007565 122 0.011
response to calcium ion GO:0051592 59 0.011
response to other organism GO:0051707 220 0.011
response to carbohydrate GO:0009743 183 0.011
vitamin a metabolic process GO:0006776 2 0.011
response to ionizing radiation GO:0010212 59 0.011
negative regulation of molecular function GO:0044092 133 0.011
response to estradiol GO:0032355 164 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
response to extracellular stimulus GO:0009991 380 0.011
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.011
regulation of protein localization GO:0032880 81 0.011
embryonic skeletal system development GO:0048706 3 0.011
cell morphogenesis GO:0000902 142 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
positive regulation of stress activated mapk cascade GO:0032874 17 0.011
positive regulation of interleukin 1 secretion GO:0050716 3 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.011
positive regulation of homeostatic process GO:0032846 49 0.011
cellular response to external stimulus GO:0071496 118 0.011
regulation of catalytic activity GO:0050790 304 0.011
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
positive regulation of defense response GO:0031349 37 0.011
cognition GO:0050890 92 0.011
multicellular organismal signaling GO:0035637 44 0.011
transmission of nerve impulse GO:0019226 42 0.011
positive regulation of leukocyte activation GO:0002696 30 0.010
regulation of nucleotide biosynthetic process GO:0030808 47 0.010
regulation of response to wounding GO:1903034 69 0.010
response to morphine GO:0043278 27 0.010
purine containing compound metabolic process GO:0072521 253 0.010
development of primary sexual characteristics GO:0045137 107 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.010
neuron projection morphogenesis GO:0048812 122 0.010
regulation of anatomical structure size GO:0090066 135 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
divalent metal ion transport GO:0070838 132 0.010
regulation of neural precursor cell proliferation GO:2000177 16 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.010
sensory perception of bitter taste GO:0050913 4 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
negative regulation of neuron death GO:1901215 69 0.010
positive regulation of cytokine production GO:0001819 42 0.010

Usp25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.043
retinal disease DOID:5679 0 0.037
retinal degeneration DOID:8466 0 0.037
cone rod dystrophy DOID:0050572 0 0.037
sensory system disease DOID:0050155 0 0.037
eye and adnexa disease DOID:1492 0 0.037
eye disease DOID:5614 0 0.037
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014