Rattus norvegicus

0 known processes

Vax2

ventral anterior homeobox 2

Vax2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inorganic ion transmembrane transport GO:0098660 229 0.457
transcription dna templated GO:0006351 377 0.352
Mouse
transmembrane transport GO:0055085 412 0.320
positive regulation of rna metabolic process GO:0051254 203 0.296
rhythmic process GO:0048511 156 0.278
regulation of transcription dna templated GO:0006355 374 0.268
Mouse
regulation of rna metabolic process GO:0051252 391 0.258
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.246
Mouse
ion transmembrane transport GO:0034220 365 0.235
regulation of cellular localization GO:0060341 263 0.234
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.218
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.215
negative regulation of metabolic process GO:0009892 331 0.210
Mouse
transcription from rna polymerase ii promoter GO:0006366 252 0.199
Mouse
rna biosynthetic process GO:0032774 380 0.180
Mouse
negative regulation of biosynthetic process GO:0009890 168 0.177
Mouse
inorganic cation transmembrane transport GO:0098662 202 0.172
negative regulation of nucleic acid templated transcription GO:1903507 117 0.165
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.165
nucleic acid templated transcription GO:0097659 379 0.160
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.159
negative regulation of cellular biosynthetic process GO:0031327 161 0.158
Mouse
cation transmembrane transport GO:0098655 263 0.158
negative regulation of macromolecule metabolic process GO:0010605 260 0.156
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 116 0.151
cation transport GO:0006812 382 0.146
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.145
Mouse
rna metabolic process GO:0016070 406 0.134
Mouse
regulation of molecular function GO:0065009 398 0.127
positive regulation of cellular biosynthetic process GO:0031328 295 0.120
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.120
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.111
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 197 0.109
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.109
Mouse
brain development GO:0007420 247 0.105
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.104
response to peptide GO:1901652 292 0.098
circadian rhythm GO:0007623 88 0.097
positive regulation of rna biosynthetic process GO:1902680 197 0.097
regulation of cell proliferation GO:0042127 359 0.093
response to peptide hormone GO:0043434 278 0.093
negative regulation of rna biosynthetic process GO:1902679 118 0.086
Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.086
Mouse
neurological system process GO:0050877 219 0.084
anion transport GO:0006820 178 0.084
cellular response to lipid GO:0071396 201 0.084
negative regulation of transcription dna templated GO:0045892 116 0.083
Mouse
positive regulation of transcription dna templated GO:0045893 197 0.076
regulation of phosphate metabolic process GO:0019220 349 0.076
organic anion transport GO:0015711 132 0.075
positive regulation of cell proliferation GO:0008284 249 0.073
sensory perception GO:0007600 101 0.070
anatomical structure morphogenesis GO:0009653 298 0.068
Zebrafish Mouse
circulatory system process GO:0003013 183 0.067
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.066
positive regulation of gene expression GO:0010628 244 0.063
metal ion transport GO:0030001 289 0.060
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.059
central nervous system development GO:0007417 311 0.056
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.055
Mouse
regulation of system process GO:0044057 208 0.054
positive regulation of phosphate metabolic process GO:0045937 262 0.054
eye development GO:0001654 50 0.052
Zebrafish Mouse
lipid metabolic process GO:0006629 283 0.052
heart morphogenesis GO:0003007 3 0.052
regulation of phosphorus metabolic process GO:0051174 349 0.049
positive regulation of multicellular organismal process GO:0051240 387 0.048
organic acid transport GO:0015849 116 0.044
tissue development GO:0009888 252 0.044
Zebrafish Mouse
circulatory system development GO:0072359 134 0.043
homeostatic process GO:0042592 331 0.043
response to nutrient levels GO:0031667 370 0.042
negative regulation of rna metabolic process GO:0051253 123 0.041
Mouse
negative regulation of programmed cell death GO:0043069 183 0.040
Zebrafish
reproduction GO:0000003 245 0.040
cellular homeostasis GO:0019725 252 0.039
positive regulation of transport GO:0051050 245 0.039
regulation of cellular component organization GO:0051128 368 0.039
Zebrafish
regulation of protein phosphorylation GO:0001932 183 0.039
regulation of signal transduction GO:0009966 318 0.039
Zebrafish
regulation of catalytic activity GO:0050790 304 0.038
cellular ion homeostasis GO:0006873 184 0.037
single organism behavior GO:0044708 130 0.037
protein phosphorylation GO:0006468 345 0.037
blood circulation GO:0008015 183 0.037
regulation of ion transport GO:0043269 245 0.036
cellular calcium ion homeostasis GO:0006874 160 0.036
apoptotic process GO:0006915 381 0.035
Zebrafish
positive regulation of response to stimulus GO:0048584 285 0.034
response to molecule of bacterial origin GO:0002237 194 0.032
chemical homeostasis GO:0048878 292 0.032
regulation of ion transmembrane transport GO:0034765 121 0.032
ion homeostasis GO:0050801 212 0.031
negative regulation of molecular function GO:0044092 133 0.031
cardiovascular system development GO:0072358 134 0.031
negative regulation of gene expression GO:0010629 199 0.031
Mouse
regulation of transferase activity GO:0051338 123 0.030
regulation of hormone levels GO:0010817 187 0.030
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
cellular chemical homeostasis GO:0055082 247 0.029
single organism reproductive process GO:0044702 297 0.029
positive regulation of developmental process GO:0051094 283 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
rhythmic behavior GO:0007622 24 0.027
regulation of metal ion transport GO:0010959 118 0.027
intracellular transport GO:0046907 185 0.027
cellular response to abiotic stimulus GO:0071214 85 0.027
cell cycle GO:0007049 101 0.027
monovalent inorganic cation transport GO:0015672 172 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
single organism biosynthetic process GO:0044711 342 0.026
regulation of kinase activity GO:0043549 117 0.026
response to estradiol GO:0032355 164 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
Mouse
positive regulation of protein metabolic process GO:0051247 178 0.026
cellular lipid metabolic process GO:0044255 208 0.026
regulation of phosphorylation GO:0042325 248 0.026
response to extracellular stimulus GO:0009991 380 0.025
cellular response to organic cyclic compound GO:0071407 202 0.025
positive regulation of secretion GO:0051047 140 0.025
positive regulation of cell differentiation GO:0045597 217 0.024
positive regulation of molecular function GO:0044093 230 0.024
carboxylic acid transport GO:0046942 115 0.024
cellular metal ion homeostasis GO:0006875 172 0.024
divalent inorganic cation transport GO:0072511 134 0.024
single organism intracellular transport GO:1902582 166 0.023
regulation of protein kinase activity GO:0045859 105 0.023
anion transmembrane transport GO:0098656 77 0.023
regulation of ion transmembrane transporter activity GO:0032412 48 0.023
intracellular signal transduction GO:0035556 314 0.023
Zebrafish
cellular response to stress GO:0033554 269 0.023
programmed cell death GO:0012501 392 0.022
Zebrafish
carbohydrate derivative metabolic process GO:1901135 346 0.022
head development GO:0060322 247 0.022
Mouse
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
negative regulation of phosphate metabolic process GO:0045936 80 0.022
response to bacterium GO:0009617 200 0.022
positive regulation of immune system process GO:0002684 90 0.022
secretion GO:0046903 307 0.022
divalent inorganic cation homeostasis GO:0072507 165 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
regulation of multicellular organismal development GO:2000026 376 0.021
Zebrafish
muscle system process GO:0003012 115 0.021
response to nutrient GO:0007584 248 0.021
response to hexose GO:0009746 144 0.021
response to metal ion GO:0010038 253 0.021
positive regulation of cell communication GO:0010647 271 0.021
heart development GO:0007507 72 0.020
behavior GO:0007610 205 0.020
Zebrafish
cellular ketone metabolic process GO:0042180 51 0.020
regulation of heart contraction GO:0008016 48 0.020
cellular component movement GO:0006928 248 0.020
Zebrafish
secretion by cell GO:0032940 248 0.020
divalent metal ion transport GO:0070838 132 0.020
insulin like growth factor receptor signaling pathway GO:0048009 3 0.020
sodium ion transmembrane transport GO:0035725 67 0.019
regulation of calcium ion transport GO:0051924 77 0.019
neuron death GO:0070997 127 0.019
regulation of protein modification process GO:0031399 194 0.019
hormone metabolic process GO:0042445 69 0.019
response to glucose GO:0009749 136 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
cation homeostasis GO:0055080 195 0.019
vesicle mediated transport GO:0016192 181 0.019
negative regulation of apoptotic process GO:0043066 181 0.018
Zebrafish
response to glucocorticoid GO:0051384 223 0.018
regulation of protein metabolic process GO:0051246 289 0.018
response to cytokine GO:0034097 215 0.018
response to hypoxia GO:0001666 231 0.018
heart contraction GO:0060047 57 0.018
heart process GO:0003015 57 0.018
regulation of blood circulation GO:1903522 110 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
axis specification GO:0009798 4 0.017
Mouse
tube development GO:0035295 89 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
regulation of secretion by cell GO:1903530 208 0.017
metal ion homeostasis GO:0055065 186 0.017
regulation of membrane potential GO:0042391 110 0.017
neuron fate commitment GO:0048663 4 0.017
negative regulation of cell death GO:0060548 229 0.017
Zebrafish
g protein coupled receptor signaling pathway GO:0007186 242 0.017
positive regulation of protein modification process GO:0031401 142 0.017
response to inorganic substance GO:0010035 377 0.017
calcium ion transport GO:0006816 131 0.017
positive regulation of signaling GO:0023056 270 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
regulation of programmed cell death GO:0043067 341 0.016
Zebrafish
response to oxygen levels GO:0070482 265 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
protein complex assembly GO:0006461 263 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
forebrain development GO:0030900 98 0.016
Mouse
metanephric glomerulus development GO:0072224 3 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
cellular component biogenesis GO:0044085 368 0.016
developmental process involved in reproduction GO:0003006 159 0.016
reproductive process GO:0022414 372 0.015
response to decreased oxygen levels GO:0036293 237 0.015
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.015
regulation of blood pressure GO:0008217 83 0.015
cardiac chamber development GO:0003205 1 0.015
catabolic process GO:0009056 351 0.015
positive regulation of nervous system development GO:0051962 178 0.015
cellular amine metabolic process GO:0044106 38 0.015
vasculature development GO:0001944 70 0.015
adult locomotory behavior GO:0008344 4 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
cellular cation homeostasis GO:0030003 180 0.015
regulation of transmembrane transport GO:0034762 122 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
sleep GO:0030431 30 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
positive regulation of protein kinase activity GO:0045860 73 0.014
circadian sleep wake cycle GO:0042745 23 0.014
organophosphate metabolic process GO:0019637 370 0.014
response to carbohydrate GO:0009743 183 0.014
synaptic transmission GO:0007268 235 0.014
positive regulation of ion transport GO:0043270 94 0.014
steroid metabolic process GO:0008202 73 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
nucleotide metabolic process GO:0009117 279 0.013
neuron differentiation GO:0030182 368 0.013
Zebrafish Mouse
activation of protein kinase activity GO:0032147 47 0.013
organ morphogenesis GO:0009887 75 0.013
Zebrafish Mouse
growth GO:0040007 165 0.013
immune system process GO:0002376 204 0.013
regulation of nervous system development GO:0051960 264 0.013
Zebrafish
multicellular organism reproduction GO:0032504 233 0.013
sensory perception of pain GO:0019233 73 0.013
response to toxic substance GO:0009636 133 0.013
defense response GO:0006952 194 0.013
renal system development GO:0072001 67 0.013
organic acid metabolic process GO:0006082 292 0.013
regulation of postsynaptic membrane potential GO:0060078 25 0.013
regulation of homeostatic process GO:0032844 101 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
negative regulation of signal transduction GO:0009968 83 0.012
Zebrafish
multi organism reproductive process GO:0044703 262 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
regulation of protein localization GO:0032880 81 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
response to alkaloid GO:0043279 132 0.012
camera type eye development GO:0043010 48 0.012
Zebrafish Mouse
eye morphogenesis GO:0048592 4 0.012
Zebrafish Mouse
transmission of nerve impulse GO:0019226 42 0.012
amine metabolic process GO:0009308 38 0.012
regulation of peptide transport GO:0090087 87 0.012
negative regulation of cell communication GO:0010648 158 0.011
Zebrafish
dna metabolic process GO:0006259 96 0.011
immune system development GO:0002520 41 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
negative regulation of transport GO:0051051 136 0.011
response to vitamin GO:0033273 131 0.011
regulation of secretion GO:0051046 224 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
regulation of insulin secretion GO:0050796 65 0.011
purine containing compound metabolic process GO:0072521 253 0.011
response to corticosteroid GO:0031960 235 0.011
negative regulation of protein phosphorylation GO:0001933 44 0.011
cell cell signaling GO:0007267 335 0.011
membrane depolarization GO:0051899 32 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
response to biotic stimulus GO:0009607 226 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.010
neuron apoptotic process GO:0051402 88 0.010
regulation of nucleotide biosynthetic process GO:0030808 47 0.010
regulation of mapk cascade GO:0043408 116 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
actin mediated cell contraction GO:0070252 12 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
sex differentiation GO:0007548 113 0.010
regulation of transmembrane transporter activity GO:0022898 49 0.010
embryonic axis specification GO:0000578 1 0.010
synapse organization GO:0050808 46 0.010
regulation of apoptotic process GO:0042981 335 0.010
Zebrafish
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
response to ethanol GO:0045471 162 0.010

Vax2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.373
disease of anatomical entity DOID:7 0 0.373
eye and adnexa disease DOID:1492 0 0.373
nervous system disease DOID:863 0 0.373
eye disease DOID:5614 0 0.373
retinal disease DOID:5679 0 0.093
night blindness DOID:8499 0 0.089
congenital stationary night blindness DOID:0050534 0 0.046
retinal degeneration DOID:8466 0 0.042
retinitis pigmentosa DOID:10584 0 0.042
central nervous system disease DOID:331 0 0.013