Rattus norvegicus

147 known processes

Vcp

valosin-containing protein

Vcp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
golgi organization GO:0007030 17 0.690
macromolecular complex subunit organization GO:0043933 339 0.633
trna aminoacylation GO:0043039 3 0.598
regulation of cellular protein metabolic process GO:0032268 267 0.532
protein complex subunit organization GO:0071822 302 0.369
transcription dna templated GO:0006351 377 0.353
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 3 0.327
organelle organization GO:0006996 266 0.308
Yeast Worm
transcription initiation from rna polymerase ii promoter GO:0006367 3 0.307
protein complex biogenesis GO:0070271 263 0.226
macromolecular complex assembly GO:0065003 273 0.223
protein complex assembly GO:0006461 263 0.218
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.212
positive regulation of gene expression GO:0010628 244 0.204
cellular component biogenesis GO:0044085 368 0.201
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.199
macromolecule catabolic process GO:0009057 58 0.178
cellular component assembly GO:0022607 360 0.177
chromosome segregation GO:0007059 2 0.169
Yeast
protein catabolic process GO:0030163 30 0.166
rna biosynthetic process GO:0032774 380 0.159
apoptotic process GO:0006915 381 0.155
Mouse
atp catabolic process GO:0006200 54 0.153
proteolysis GO:0006508 175 0.152
programmed cell death GO:0012501 392 0.149
Mouse
negative regulation of nervous system development GO:0051961 79 0.141
double strand break repair GO:0006302 1 0.140
Human
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.124
vesicle mediated transport GO:0016192 181 0.119
negative regulation of neurogenesis GO:0050768 78 0.116
response to decreased oxygen levels GO:0036293 237 0.111
membrane organization GO:0061024 94 0.104
Yeast
regulation of transcription dna templated GO:0006355 374 0.104
regulation of rna metabolic process GO:0051252 391 0.102
translation GO:0006412 35 0.099
positive regulation of transcription dna templated GO:0045893 197 0.099
organic substance catabolic process GO:1901575 316 0.098
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.096
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 3 0.093
mesoderm morphogenesis GO:0048332 1 0.092
response to oxygen levels GO:0070482 265 0.087
spindle organization GO:0007051 2 0.083
Yeast
positive regulation of biosynthetic process GO:0009891 319 0.082
response to hypoxia GO:0001666 231 0.080
negative regulation of cell development GO:0010721 82 0.080
oxidation reduction process GO:0055114 304 0.078
growth GO:0040007 165 0.076
Worm
negative regulation of multicellular organismal process GO:0051241 203 0.076
reproductive process GO:0022414 372 0.075
Worm
mitotic spindle organization GO:0007052 2 0.073
Yeast
tissue development GO:0009888 252 0.071
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.068
membrane fusion GO:0061025 26 0.066
Yeast
regulation of programmed cell death GO:0043067 341 0.066
Mouse
regulation of apoptotic signaling pathway GO:2001233 13 0.065
multi organism reproductive process GO:0044703 262 0.064
modification dependent macromolecule catabolic process GO:0043632 14 0.062
chromatin assembly or disassembly GO:0006333 1 0.062
positive regulation of rna metabolic process GO:0051254 203 0.062
regulation of cellular component organization GO:0051128 368 0.062
Human Yeast
anatomical structure morphogenesis GO:0009653 298 0.061
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 3 0.059
negative regulation of cell differentiation GO:0045596 99 0.057
ubiquitin dependent protein catabolic process GO:0006511 14 0.057
positive regulation of signaling GO:0023056 270 0.057
multicellular organismal reproductive process GO:0048609 233 0.056
regulation of behavior GO:0050795 61 0.055
regulation of phosphate metabolic process GO:0019220 349 0.055
reproductive system development GO:0061458 128 0.055
Worm
cellular protein complex assembly GO:0043623 44 0.055
regulation of protein metabolic process GO:0051246 289 0.053
regulation of rna biosynthetic process GO:2001141 381 0.052
intracellular signal transduction GO:0035556 314 0.052
regulation of system process GO:0044057 208 0.050
homeostatic process GO:0042592 331 0.049
cellular chemical homeostasis GO:0055082 247 0.049
nucleotide metabolic process GO:0009117 279 0.048
cellular macromolecular complex assembly GO:0034622 58 0.048
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.047
cellular macromolecule catabolic process GO:0044265 29 0.047
regulation of apoptotic process GO:0042981 335 0.047
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.046
positive regulation of cellular biosynthetic process GO:0031328 295 0.046
cell cycle GO:0007049 101 0.045
Yeast Worm
single organism reproductive process GO:0044702 297 0.044
Worm
cellular response to stress GO:0033554 269 0.044
Human Yeast Worm
ras protein signal transduction GO:0007265 29 0.043
regulation of metal ion transport GO:0010959 118 0.043
negative regulation of apoptotic process GO:0043066 181 0.043
single organism intracellular transport GO:1902582 166 0.043
rhythmic process GO:0048511 156 0.043
regulation of protein targeting GO:1903533 28 0.042
cellular protein catabolic process GO:0044257 19 0.042
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.040
secretion by cell GO:0032940 248 0.040
sexual reproduction GO:0019953 148 0.039
negative regulation of cell death GO:0060548 229 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.039
mesoderm development GO:0007498 2 0.038
endocytosis GO:0006897 84 0.038
positive regulation of rna biosynthetic process GO:1902680 197 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.036
positive regulation of signal transduction GO:0009967 175 0.035
ion homeostasis GO:0050801 212 0.035
immune system process GO:0002376 204 0.035
multicellular organismal signaling GO:0035637 44 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
regulation of cell differentiation GO:0045595 320 0.034
cell growth GO:0016049 104 0.034
regulation of intracellular signal transduction GO:1902531 218 0.034
regulation of molecular function GO:0065009 398 0.033
Human Yeast Mouse
positive regulation of response to stimulus GO:0048584 285 0.033
reproduction GO:0000003 245 0.033
Worm
negative regulation of developmental process GO:0051093 125 0.033
locomotion GO:0040011 237 0.033
Worm
carboxylic acid metabolic process GO:0019752 289 0.033
regulation of signal transduction GO:0009966 318 0.032
cation homeostasis GO:0055080 195 0.032
divalent metal ion transport GO:0070838 132 0.031
regulation of cell proliferation GO:0042127 359 0.031
taxis GO:0042330 67 0.031
neurological system process GO:0050877 219 0.030
regulation of protein complex assembly GO:0043254 33 0.030
Human
cell projection morphogenesis GO:0048858 123 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
regulation of phosphorylation GO:0042325 248 0.030
regulation of neurogenesis GO:0050767 247 0.029
cellular catabolic process GO:0044248 295 0.029
protein localization to organelle GO:0033365 57 0.029
Yeast
regulation of protein catabolic process GO:0042176 16 0.029
multicellular organism reproduction GO:0032504 233 0.029
circulatory system development GO:0072359 134 0.029
positive regulation of cell death GO:0010942 184 0.029
Mouse
cellular response to nitrogen compound GO:1901699 210 0.028
negative regulation of biosynthetic process GO:0009890 168 0.028
regulation of g2 m transition of mitotic cell cycle GO:0010389 4 0.028
cellular homeostasis GO:0019725 252 0.028
cellular macromolecule localization GO:0070727 122 0.028
Human Yeast
catabolic process GO:0009056 351 0.027
cation transport GO:0006812 382 0.027
transmission of nerve impulse GO:0019226 42 0.027
protein transport GO:0015031 132 0.027
Human Yeast
regulation of kinase activity GO:0043549 117 0.026
negative regulation of rna metabolic process GO:0051253 123 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
negative regulation of cell communication GO:0010648 158 0.026
single organism catabolic process GO:0044712 283 0.026
dna metabolic process GO:0006259 96 0.025
Human
establishment of protein localization GO:0045184 141 0.025
Human Yeast
dendrite development GO:0016358 72 0.025
cellular metal ion homeostasis GO:0006875 172 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
defense response GO:0006952 194 0.024
cardiovascular system development GO:0072358 134 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
negative regulation of rna biosynthetic process GO:1902679 118 0.024
regulation of cellular component biogenesis GO:0044087 86 0.024
Human
single organism organelle organization GO:1902589 180 0.023
Yeast
embryo development GO:0009790 49 0.023
Zebrafish Worm
cellular component movement GO:0006928 248 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
chemical homeostasis GO:0048878 292 0.022
regulation of cell growth GO:0001558 85 0.022
response to wounding GO:0009611 254 0.022
response to hyperoxia GO:0055093 45 0.022
negative regulation of metabolic process GO:0009892 331 0.022
cell cycle g2 m phase transition GO:0044839 6 0.022
gamete generation GO:0007276 124 0.022
regulation of cell development GO:0060284 263 0.022
cellular response to oxidative stress GO:0034599 76 0.021
developmental process involved in reproduction GO:0003006 159 0.021
Worm
neuromuscular process GO:0050905 2 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
positive regulation of cellular component biogenesis GO:0044089 55 0.021
Human
brain development GO:0007420 247 0.020
chromatin remodeling GO:0006338 3 0.020
negative regulation of molecular function GO:0044092 133 0.020
coenzyme metabolic process GO:0006732 86 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
regulation of protein modification process GO:0031399 194 0.020
Human Yeast Zebrafish
dna templated transcriptional preinitiation complex assembly GO:0070897 3 0.020
formation of primary germ layer GO:0001704 1 0.020
purine nucleoside monophosphate catabolic process GO:0009128 55 0.020
regeneration GO:0031099 163 0.020
hindlimb morphogenesis GO:0035137 2 0.019
protein phosphorylation GO:0006468 345 0.019
single organism nuclear import GO:1902593 35 0.019
negative regulation of cellular component organization GO:0051129 83 0.019
chromosome organization GO:0051276 36 0.019
Yeast
regulation of cell cycle g2 m phase transition GO:1902749 4 0.019
rna metabolic process GO:0016070 406 0.019
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 122 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
Human Yeast
negative regulation of neuron differentiation GO:0045665 62 0.018
gastrulation GO:0007369 2 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
organelle fission GO:0048285 25 0.018
Yeast Worm
cellular response to endogenous stimulus GO:0071495 377 0.017
lipid storage GO:0019915 1 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
response to ethanol GO:0045471 162 0.017
regulation of establishment of protein localization GO:0070201 69 0.017
negative regulation of cell projection organization GO:0031345 50 0.017
adult locomotory behavior GO:0008344 4 0.017
secretion GO:0046903 307 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
metal ion homeostasis GO:0055065 186 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
eye morphogenesis GO:0048592 4 0.016
regulation of striated muscle contraction GO:0006942 21 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.016
regulation of catalytic activity GO:0050790 304 0.016
Human Yeast Mouse
regulation of stem cell differentiation GO:2000736 2 0.016
organic acid metabolic process GO:0006082 292 0.016
aromatic compound catabolic process GO:0019439 168 0.016
positive regulation of cell communication GO:0010647 271 0.016
cellular component morphogenesis GO:0032989 155 0.016
cellular ketone metabolic process GO:0042180 51 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
Worm
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.016
regulation of dendrite development GO:0050773 59 0.016
chemosensory behavior GO:0007635 2 0.016
neuronal action potential GO:0019228 35 0.015
regulation of developmental growth GO:0048638 45 0.015
Worm
regulation of nervous system development GO:0051960 264 0.015
aging GO:0007568 241 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
male gamete generation GO:0048232 99 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
regulation of response to stress GO:0080134 126 0.015
wound healing GO:0042060 122 0.015
protein import into nucleus GO:0006606 35 0.015
regulation of proteolysis GO:0030162 66 0.015
glucan metabolic process GO:0044042 23 0.015
cellular response to lipid GO:0071396 201 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
nadp metabolic process GO:0006739 13 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
chordate embryonic development GO:0043009 18 0.014
central nervous system development GO:0007417 311 0.014
cell morphogenesis GO:0000902 142 0.014
signal release GO:0023061 145 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
regulation of cellular localization GO:0060341 263 0.014
Yeast
metal ion transport GO:0030001 289 0.014
gonad development GO:0008406 104 0.014
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
response to axon injury GO:0048678 59 0.014
negative regulation of protein processing GO:0010955 47 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
endomembrane system organization GO:0010256 48 0.013
regulation of heart contraction GO:0008016 48 0.013
cytoplasmic transport GO:0016482 115 0.013
dna templated transcription initiation GO:0006352 4 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
cellular response to dna damage stimulus GO:0006974 19 0.013
Human
neuron projection development GO:0031175 273 0.013
positive regulation of blood circulation GO:1903524 65 0.013
nicotinamide nucleotide metabolic process GO:0046496 28 0.013
regulation of muscle system process GO:0090257 79 0.013
regulation of growth GO:0040008 105 0.013
Worm
nuclear division GO:0000280 22 0.013
Yeast Worm
regulation of transferase activity GO:0051338 123 0.013
regulation of protein kinase activity GO:0045859 105 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
regulation of hydrolase activity GO:0051336 143 0.013
Human Mouse
protein localization GO:0008104 191 0.013
Human Yeast
regulation of intracellular protein transport GO:0033157 34 0.013
nucleoside catabolic process GO:0009164 126 0.013
regulation of wnt signaling pathway GO:0030111 8 0.013
chromosome condensation GO:0030261 3 0.012
regulation of blood circulation GO:1903522 110 0.012
cellular amine metabolic process GO:0044106 38 0.012
mitotic cell cycle GO:0000278 49 0.012
Yeast
anterograde axon cargo transport GO:0008089 1 0.012
serine family amino acid metabolic process GO:0009069 12 0.012
de novo posttranslational protein folding GO:0051084 2 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
heart development GO:0007507 72 0.012
cellular response to inorganic substance GO:0071241 65 0.012
Yeast
chromatin modification GO:0016568 33 0.012
Yeast
embryo development ending in birth or egg hatching GO:0009792 22 0.012
Worm
blood vessel development GO:0001568 69 0.012
cellular modified amino acid metabolic process GO:0006575 61 0.012
rna catabolic process GO:0006401 3 0.012
Yeast
head development GO:0060322 247 0.012
axon ensheathment GO:0008366 40 0.012
trna metabolic process GO:0006399 4 0.011
response to activity GO:0014823 73 0.011
developmental growth GO:0048589 100 0.011
Worm
oxidoreduction coenzyme metabolic process GO:0006733 31 0.011
intracellular transport GO:0046907 185 0.011
negative regulation of signaling GO:0023057 157 0.011
cell projection organization GO:0030030 302 0.011
negative regulation of gene expression GO:0010629 199 0.011
cellular protein localization GO:0034613 122 0.011
Human Yeast
exocytosis GO:0006887 60 0.011
nucleic acid templated transcription GO:0097659 379 0.011
posttranscriptional regulation of gene expression GO:0010608 37 0.011
cofactor metabolic process GO:0051186 95 0.011
cognition GO:0050890 92 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
chemotaxis GO:0006935 66 0.011
multi multicellular organism process GO:0044706 138 0.011
positive regulation of cell growth GO:0030307 44 0.011
response to metal ion GO:0010038 253 0.011
Yeast
single organism cellular localization GO:1902580 102 0.010
regulation of neuron differentiation GO:0045664 208 0.010
regulation of nucleocytoplasmic transport GO:0046822 28 0.010
alcohol metabolic process GO:0006066 77 0.010
synaptic vesicle endocytosis GO:0048488 4 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
selenium compound metabolic process GO:0001887 2 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
Mouse
trna aminoacylation for protein translation GO:0006418 3 0.010

Vcp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
Human
nervous system disease DOID:863 0 0.053
Human
sensory system disease DOID:0050155 0 0.011
central nervous system disease DOID:331 0 0.011
Human