Rattus norvegicus

0 known processes

Wdfy1

WD repeat and FYVE domain containing 1

(Aliases: MGC93914)

Wdfy1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of translational initiation GO:0045947 5 0.539
macromolecule localization GO:0033036 252 0.250
histone h3 k4 demethylation GO:0034720 2 0.169
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.161
vesicle mediated transport GO:0016192 181 0.111
cellular response to nitrogen compound GO:1901699 210 0.105
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.103
secretion GO:0046903 307 0.098
cellular component assembly GO:0022607 360 0.096
negative regulation of metabolic process GO:0009892 331 0.092
cellular component biogenesis GO:0044085 368 0.090
organic substance catabolic process GO:1901575 316 0.088
cellular response to endogenous stimulus GO:0071495 377 0.087
lens fiber cell differentiation GO:0070306 3 0.082
single organism reproductive process GO:0044702 297 0.081
tissue development GO:0009888 252 0.080
rna metabolic process GO:0016070 406 0.078
purine nucleoside metabolic process GO:0042278 169 0.075
response to nutrient levels GO:0031667 370 0.073
anatomical structure morphogenesis GO:0009653 298 0.072
neuron differentiation GO:0030182 368 0.068
multicellular organism reproduction GO:0032504 233 0.067
negative regulation of cellular metabolic process GO:0031324 281 0.067
organic acid metabolic process GO:0006082 292 0.066
protein complex subunit organization GO:0071822 302 0.065
nucleoside triphosphate metabolic process GO:0009141 144 0.064
transcription dna templated GO:0006351 377 0.064
macromolecular complex assembly GO:0065003 273 0.062
regulation of phosphorus metabolic process GO:0051174 349 0.062
regulation of catalytic activity GO:0050790 304 0.062
oxoacid metabolic process GO:0043436 290 0.060
epithelial cell differentiation GO:0030855 71 0.059
transmembrane transport GO:0055085 412 0.058
mrna metabolic process GO:0016071 20 0.058
small gtpase mediated signal transduction GO:0007264 36 0.056
regulation of phosphate metabolic process GO:0019220 349 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.054
lipid metabolic process GO:0006629 283 0.053
regulation of protein localization GO:0032880 81 0.052
regulation of nucleic acid templated transcription GO:1903506 380 0.051
production of mirnas involved in gene silencing by mirna GO:0035196 1 0.051
purine nucleotide metabolic process GO:0006163 229 0.051
protein oligomerization GO:0051259 191 0.051
carboxylic acid metabolic process GO:0019752 289 0.049
protein localization GO:0008104 191 0.049
regulation of rna biosynthetic process GO:2001141 381 0.049
regulation of secretion GO:0051046 224 0.048
olfactory learning GO:0008355 1 0.048
cation transmembrane transport GO:0098655 263 0.047
cellular response to stress GO:0033554 269 0.046
positive regulation of response to stimulus GO:0048584 285 0.046
regulation of cellular localization GO:0060341 263 0.046
regulation of protein metabolic process GO:0051246 289 0.046
cell cell signaling GO:0007267 335 0.045
positive regulation of molecular function GO:0044093 230 0.045
regulation of hydrolase activity GO:0051336 143 0.045
catabolic process GO:0009056 351 0.044
response to inorganic substance GO:0010035 377 0.044
purine ribonucleotide metabolic process GO:0009150 227 0.044
cellular lipid metabolic process GO:0044255 208 0.043
regulation of signal transduction GO:0009966 318 0.043
oxidation reduction process GO:0055114 304 0.043
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.043
regulation of cellular component organization GO:0051128 368 0.042
negative regulation of cell differentiation GO:0045596 99 0.042
organonitrogen compound catabolic process GO:1901565 179 0.042
ion transmembrane transport GO:0034220 365 0.040
macromolecular complex subunit organization GO:0043933 339 0.040
ribose phosphate metabolic process GO:0019693 235 0.040
ribonucleotide metabolic process GO:0009259 231 0.040
organelle organization GO:0006996 266 0.040
response to camp GO:0051591 91 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
positive regulation of protein phosphorylation GO:0001934 135 0.039
nucleic acid templated transcription GO:0097659 379 0.039
homeostatic process GO:0042592 331 0.039
locomotion GO:0040011 237 0.039
ribonucleoside triphosphate metabolic process GO:0009199 141 0.038
glycolytic process GO:0006096 17 0.037
protein phosphorylation GO:0006468 345 0.037
carbohydrate derivative catabolic process GO:1901136 147 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.036
regulation of cellular protein metabolic process GO:0032268 267 0.036
organophosphate metabolic process GO:0019637 370 0.036
regulation of gene expression epigenetic GO:0040029 10 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.035
monocarboxylic acid metabolic process GO:0032787 152 0.035
neuron projection morphogenesis GO:0048812 122 0.034
dsrna fragmentation GO:0031050 1 0.034
fatty acid metabolic process GO:0006631 99 0.034
regulation of transcription dna templated GO:0006355 374 0.034
regulation of secretion by cell GO:1903530 208 0.034
defense response GO:0006952 194 0.034
cell motility GO:0048870 202 0.034
inorganic cation transmembrane transport GO:0098662 202 0.033
single organism membrane organization GO:0044802 74 0.033
intracellular signal transduction GO:0035556 314 0.033
purine containing compound catabolic process GO:0072523 138 0.033
multi organism reproductive process GO:0044703 262 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.032
intracellular transport GO:0046907 185 0.031
positive regulation of signaling GO:0023056 270 0.031
response to extracellular stimulus GO:0009991 380 0.031
single organism intracellular transport GO:1902582 166 0.031
cellular ketone metabolic process GO:0042180 51 0.031
cellular response to organonitrogen compound GO:0071417 197 0.031
purine ribonucleoside metabolic process GO:0046128 168 0.031
establishment of protein localization GO:0045184 141 0.030
cellular catabolic process GO:0044248 295 0.030
ribonucleoside catabolic process GO:0042454 126 0.030
cellular response to oxygen containing compound GO:1901701 386 0.030
single organism catabolic process GO:0044712 283 0.029
negative regulation of multicellular organismal process GO:0051241 203 0.029
neuron development GO:0048666 286 0.029
positive regulation of apoptotic process GO:0043065 154 0.028
protein complex biogenesis GO:0070271 263 0.028
positive regulation of nucleotide metabolic process GO:0045981 91 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
positive regulation of signal transduction GO:0009967 175 0.028
regulation of purine nucleotide metabolic process GO:1900542 115 0.028
exocytosis GO:0006887 60 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
negative regulation of molecular function GO:0044092 133 0.028
nucleoside metabolic process GO:0009116 179 0.028
reproductive process GO:0022414 372 0.028
purine containing compound metabolic process GO:0072521 253 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
membrane organization GO:0061024 94 0.027
glycosyl compound metabolic process GO:1901657 182 0.026
circadian rhythm GO:0007623 88 0.026
purine nucleoside catabolic process GO:0006152 124 0.026
positive regulation of cell communication GO:0010647 271 0.026
ncrna processing GO:0034470 3 0.025
positive regulation of stem cell differentiation GO:2000738 2 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
growth GO:0040007 165 0.025
purine nucleoside triphosphate metabolic process GO:0009144 141 0.025
organic cyclic compound catabolic process GO:1901361 175 0.025
guanosine containing compound catabolic process GO:1901069 71 0.025
response to fibroblast growth factor GO:0071774 29 0.025
golgi vesicle transport GO:0048193 22 0.025
purine nucleotide catabolic process GO:0006195 136 0.024
regulation of canonical wnt signaling pathway GO:0060828 4 0.024
response to cytokine GO:0034097 215 0.024
neurological system process GO:0050877 219 0.024
regulation of bmp signaling pathway GO:0030510 2 0.024
circulatory system process GO:0003013 183 0.024
head development GO:0060322 247 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
regulation of cell development GO:0060284 263 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
ribonucleoside metabolic process GO:0009119 174 0.023
negative regulation of phosphorus metabolic process GO:0010563 80 0.023
single organism biosynthetic process GO:0044711 342 0.023
regulation of cell differentiation GO:0045595 320 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
regulation of apoptotic process GO:0042981 335 0.023
response to oxygen levels GO:0070482 265 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
protein complex assembly GO:0006461 263 0.022
positive regulation of rac gtpase activity GO:0032855 5 0.022
nucleotide catabolic process GO:0009166 139 0.022
heterocycle catabolic process GO:0046700 167 0.022
negative regulation of gene expression GO:0010629 199 0.022
dephosphorylation GO:0016311 98 0.022
dna metabolic process GO:0006259 96 0.022
cytokinetic process GO:0032506 1 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
nucleotide metabolic process GO:0009117 279 0.022
rab protein signal transduction GO:0032482 1 0.021
localization of cell GO:0051674 202 0.021
regulation of sister chromatid segregation GO:0033045 1 0.021
regulation of molecular function GO:0065009 398 0.021
purine nucleoside triphosphate catabolic process GO:0009146 122 0.021
cellular chemical homeostasis GO:0055082 247 0.021
regulation of protein modification process GO:0031399 194 0.021
cellular amine metabolic process GO:0044106 38 0.020
regulation of gamma aminobutyric acid secretion GO:0014052 6 0.020
reproductive structure development GO:0048608 128 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
response to toxic substance GO:0009636 133 0.020
amine metabolic process GO:0009308 38 0.020
neuron projection development GO:0031175 273 0.020
regulation of nervous system development GO:0051960 264 0.020
cation transport GO:0006812 382 0.020
amino acid transport GO:0006865 70 0.020
positive regulation of developmental process GO:0051094 283 0.020
ribonucleotide catabolic process GO:0009261 136 0.020
regulation of transporter activity GO:0032409 50 0.020
response to other organism GO:0051707 220 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
ras protein signal transduction GO:0007265 29 0.019
regulation of phosphorylation GO:0042325 248 0.019
endoplasmic reticulum organization GO:0007029 1 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
regulation of cell migration GO:0030334 128 0.019
regulation of synaptic transmission GO:0050804 141 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
protein homooligomerization GO:0051260 91 0.019
regulation of cellular component movement GO:0051270 150 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
monocarboxylic acid transport GO:0015718 52 0.018
positive regulation of catabolic process GO:0009896 78 0.018
anion transport GO:0006820 178 0.018
cell growth GO:0016049 104 0.018
neural crest cell differentiation GO:0014033 2 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
regulation of map kinase activity GO:0043405 53 0.018
cell morphogenesis GO:0000902 142 0.018
regulation of cell projection organization GO:0031344 175 0.018
reproduction GO:0000003 245 0.018
ribonucleotide biosynthetic process GO:0009260 85 0.018
cell projection organization GO:0030030 302 0.018
positive regulation of cellular catabolic process GO:0031331 71 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
olfactory behavior GO:0042048 2 0.017
development of primary sexual characteristics GO:0045137 107 0.017
regulation of smoothened signaling pathway GO:0008589 2 0.017
gamma aminobutyric acid transport GO:0015812 8 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
central nervous system development GO:0007417 311 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
cellular macromolecule localization GO:0070727 122 0.017
regulation of stem cell differentiation GO:2000736 2 0.017
nitrogen compound transport GO:0071705 229 0.016
embryonic pattern specification GO:0009880 1 0.016
negative regulation of transport GO:0051051 136 0.016
lipid biosynthetic process GO:0008610 128 0.016
synaptic transmission GO:0007268 235 0.016
regulation of nucleotide catabolic process GO:0030811 65 0.016
cellular homeostasis GO:0019725 252 0.016
molting cycle process GO:0022404 2 0.016
biological adhesion GO:0022610 110 0.016
pigment biosynthetic process GO:0046148 4 0.016
negative regulation of neuron differentiation GO:0045665 62 0.016
regulation of cell proliferation GO:0042127 359 0.016
regulation of response to stress GO:0080134 126 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
positive regulation of secretion GO:0051047 140 0.016
organic acid biosynthetic process GO:0016053 83 0.016
calcium ion transmembrane transport GO:0070588 70 0.015
chromosome segregation GO:0007059 2 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
spindle organization GO:0007051 2 0.015
syncytium formation GO:0006949 4 0.015
small molecule biosynthetic process GO:0044283 124 0.015
response to alkaloid GO:0043279 132 0.015
positive regulation of protein kinase activity GO:0045860 73 0.015
odontogenesis GO:0042476 32 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
response to metal ion GO:0010038 253 0.015
response to growth factor GO:0070848 189 0.015
regulation of chromosome segregation GO:0051983 1 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
regulation of proteasomal protein catabolic process GO:0061136 4 0.015
regulation of transmembrane transport GO:0034762 122 0.015
response to bacterium GO:0009617 200 0.015
cell proliferation in external granule layer GO:0021924 1 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
mitochondrial rna metabolic process GO:0000959 1 0.015
response to acid chemical GO:0001101 222 0.014
organic anion transport GO:0015711 132 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
cell cycle process GO:0022402 57 0.014
epithelium development GO:0060429 96 0.014
regulation of mitotic sister chromatid segregation GO:0033047 1 0.014
development of primary male sexual characteristics GO:0046546 59 0.014
sulfur compound transport GO:0072348 8 0.014
response to decreased oxygen levels GO:0036293 237 0.014
cellular response to peptide GO:1901653 133 0.014
negative regulation of innate immune response GO:0045824 4 0.014
programmed cell death GO:0012501 392 0.014
somatic stem cell maintenance GO:0035019 2 0.014
protein transport GO:0015031 132 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
neuronal action potential GO:0019228 35 0.014
developmental process involved in reproduction GO:0003006 159 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
axonogenesis GO:0007409 71 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
regulation of membrane potential GO:0042391 110 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
single organism organelle organization GO:1902589 180 0.014
cellular carbohydrate metabolic process GO:0044262 72 0.014
jnk cascade GO:0007254 28 0.014
regulation of growth GO:0040008 105 0.014
chemosensory behavior GO:0007635 2 0.013
cytoplasmic transport GO:0016482 115 0.013
rna localization GO:0006403 4 0.013
regulation of purine nucleotide catabolic process GO:0033121 65 0.013
response to nutrient GO:0007584 248 0.013
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.013
organic acid transport GO:0015849 116 0.013
long chain fatty acid metabolic process GO:0001676 32 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
organelle inheritance GO:0048308 2 0.013
aging GO:0007568 241 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
non canonical wnt signaling pathway GO:0035567 3 0.013
regulation of cell growth GO:0001558 85 0.013
sex differentiation GO:0007548 113 0.013
regulation of cell maturation GO:1903429 3 0.013
response to external biotic stimulus GO:0043207 221 0.013
regulation of neuron differentiation GO:0045664 208 0.013
regulation of cell motility GO:2000145 131 0.013
cell cycle GO:0007049 101 0.013
response to glucocorticoid GO:0051384 223 0.013
regulation of exocytosis GO:0017157 37 0.013
gonad development GO:0008406 104 0.013
gamma aminobutyric acid secretion GO:0014051 6 0.013
ion homeostasis GO:0050801 212 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
vascular process in circulatory system GO:0003018 96 0.012
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
regulation of tube size GO:0035150 89 0.012
nucleoside catabolic process GO:0009164 126 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
eye development GO:0001654 50 0.012
response to peptide hormone GO:0043434 278 0.012
brain development GO:0007420 247 0.012
regulation of rna metabolic process GO:0051252 391 0.012
muscle structure development GO:0061061 87 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
regulation of mitochondrion organization GO:0010821 7 0.012
learning GO:0007612 33 0.012
negative regulation of developmental process GO:0051093 125 0.012
cell migration GO:0016477 197 0.012
positive regulation of transport GO:0051050 245 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
neurotransmitter uptake GO:0001504 3 0.012
reproductive system development GO:0061458 128 0.012
organelle localization GO:0051640 55 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.012
proteolysis GO:0006508 175 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
mitotic spindle organization GO:0007052 2 0.012
regulation of calcium ion transmembrane transport GO:1903169 18 0.011
immune system process GO:0002376 204 0.011
peptide transport GO:0015833 97 0.011
microtubule based process GO:0007017 36 0.011
response to biotic stimulus GO:0009607 226 0.011
anterior posterior pattern specification GO:0009952 1 0.011
coenzyme metabolic process GO:0006732 86 0.011
negative regulation of protein modification process GO:0031400 52 0.011
rhythmic process GO:0048511 156 0.011
liver development GO:0001889 90 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
neuromuscular process GO:0050905 2 0.011
positive regulation of mitochondrion organization GO:0010822 4 0.011
divalent metal ion transport GO:0070838 132 0.011
regulation of protein transport GO:0051223 68 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.011
negative regulation of signaling GO:0023057 157 0.011
secretion by cell GO:0032940 248 0.011
response to ammonium ion GO:0060359 71 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
regulation of anatomical structure size GO:0090066 135 0.011
molting cycle GO:0042303 3 0.011
positive regulation of biosynthetic process GO:0009891 319 0.011
blood circulation GO:0008015 183 0.010
anion transmembrane transport GO:0098656 77 0.010
metal ion transport GO:0030001 289 0.010
male gonad development GO:0008584 59 0.010
chromosome separation GO:0051304 1 0.010
hair follicle development GO:0001942 2 0.010
rna biosynthetic process GO:0032774 380 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
axis specification GO:0009798 4 0.010
regulation of blood vessel size GO:0050880 89 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
cerebellar granule cell precursor proliferation GO:0021930 1 0.010
regulation of cellular ketone metabolic process GO:0010565 27 0.010
negative regulation of cell death GO:0060548 229 0.010
carboxylic acid transport GO:0046942 115 0.010
negative regulation of phosphorylation GO:0042326 57 0.010
metaphase anaphase transition of cell cycle GO:0044784 1 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010
regulation of small gtpase mediated signal transduction GO:0051056 48 0.010
regulation of ion transport GO:0043269 245 0.010
positive regulation of amine transport GO:0051954 26 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.010

Wdfy1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
acquired metabolic disease DOID:0060158 0 0.020
disease of metabolism DOID:0014667 0 0.020
nutrition disease DOID:374 0 0.020
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014