Rattus norvegicus

0 known processes

Wnt2b

wingless-type MMTV integration site family, member 2B

Wnt2b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.270
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.251
positive regulation of transcription dna templated GO:0045893 197 0.213
regulation of phosphorylation GO:0042325 248 0.198
Rat
response to peptide hormone GO:0043434 278 0.186
Rat
negative regulation of cell death GO:0060548 229 0.177
regulation of rna metabolic process GO:0051252 391 0.176
regulation of rna biosynthetic process GO:2001141 381 0.176
regulation of cellular localization GO:0060341 263 0.174
cellular homeostasis GO:0019725 252 0.138
regulation of signal transduction GO:0009966 318 0.135
Human Rat
regulation of protein modification process GO:0031399 194 0.131
Rat
regulation of hormone levels GO:0010817 187 0.130
rna biosynthetic process GO:0032774 380 0.128
cation transport GO:0006812 382 0.127
protein phosphorylation GO:0006468 345 0.122
Rat
cellular component movement GO:0006928 248 0.121
intracellular signal transduction GO:0035556 314 0.115
Rat
regulation of transcription dna templated GO:0006355 374 0.102
positive regulation of cell proliferation GO:0008284 249 0.101
Rat
positive regulation of signaling GO:0023056 270 0.101
Human Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.100
anatomical structure morphogenesis GO:0009653 298 0.095
Rat
transcription dna templated GO:0006351 377 0.094
calcium ion homeostasis GO:0055074 162 0.093
regulation of phosphorus metabolic process GO:0051174 349 0.091
Rat
nucleic acid templated transcription GO:0097659 379 0.091
apoptotic process GO:0006915 381 0.090
positive regulation of gene expression GO:0010628 244 0.089
positive regulation of nucleic acid templated transcription GO:1903508 197 0.088
chemical homeostasis GO:0048878 292 0.087
negative regulation of metabolic process GO:0009892 331 0.087
homeostatic process GO:0042592 331 0.086
epithelial cell proliferation GO:0050673 54 0.084
Rat
negative regulation of response to stimulus GO:0048585 155 0.081
rna metabolic process GO:0016070 406 0.081
response to peptide GO:1901652 292 0.079
Rat
regulation of apoptotic process GO:0042981 335 0.077
transcription from rna polymerase ii promoter GO:0006366 252 0.077
nitrogen compound transport GO:0071705 229 0.076
neuron differentiation GO:0030182 368 0.075
Rat
metal ion homeostasis GO:0055065 186 0.075
cellular response to endogenous stimulus GO:0071495 377 0.070
Rat
regulation of system process GO:0044057 208 0.068
positive regulation of signal transduction GO:0009967 175 0.068
Human Rat
response to insulin GO:0032868 133 0.067
cellular chemical homeostasis GO:0055082 247 0.066
inorganic cation transmembrane transport GO:0098662 202 0.066
cellular divalent inorganic cation homeostasis GO:0072503 162 0.064
negative regulation of signaling GO:0023057 157 0.063
divalent inorganic cation homeostasis GO:0072507 165 0.063
regulation of protein metabolic process GO:0051246 289 0.062
Rat
metal ion transport GO:0030001 289 0.061
carboxylic acid metabolic process GO:0019752 289 0.059
regulation of cellular component organization GO:0051128 368 0.059
rhythmic process GO:0048511 156 0.057
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.057
regulation of membrane potential GO:0042391 110 0.056
positive regulation of phosphorylation GO:0042327 177 0.056
Rat
response to cytokine GO:0034097 215 0.056
cellular metal ion homeostasis GO:0006875 172 0.056
regulation of mapk cascade GO:0043408 116 0.056
Rat
cellular component assembly GO:0022607 360 0.055
regulation of secretion GO:0051046 224 0.055
cell projection organization GO:0030030 302 0.053
Rat
cellular calcium ion homeostasis GO:0006874 160 0.053
cellular ion homeostasis GO:0006873 184 0.052
cellular response to oxygen containing compound GO:1901701 386 0.052
Rat
negative regulation of signal transduction GO:0009968 83 0.052
cellular amine metabolic process GO:0044106 38 0.052
action potential GO:0001508 54 0.052
carboxylic acid transport GO:0046942 115 0.051
negative regulation of apoptotic process GO:0043066 181 0.051
amine metabolic process GO:0009308 38 0.050
neurological system process GO:0050877 219 0.050
hormone secretion GO:0046879 115 0.050
organic acid metabolic process GO:0006082 292 0.050
regulation of protein phosphorylation GO:0001932 183 0.049
Rat
positive regulation of response to stimulus GO:0048584 285 0.049
Human Rat
locomotion GO:0040011 237 0.048
lipid metabolic process GO:0006629 283 0.048
central nervous system development GO:0007417 311 0.048
Human
cellular response to cytokine stimulus GO:0071345 127 0.048
multicellular organismal reproductive process GO:0048609 233 0.047
learning or memory GO:0007611 90 0.047
regulation of phosphate metabolic process GO:0019220 349 0.045
Rat
monovalent inorganic cation transport GO:0015672 172 0.045
negative regulation of transcription dna templated GO:0045892 116 0.044
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.044
organic acid transport GO:0015849 116 0.043
mapk cascade GO:0000165 140 0.042
Rat
cellular response to nitrogen compound GO:1901699 210 0.042
Rat
cellular response to external stimulus GO:0071496 118 0.042
regulation of secretion by cell GO:1903530 208 0.042
inorganic ion transmembrane transport GO:0098660 229 0.041
regulation of locomotion GO:0040012 148 0.041
amino acid transport GO:0006865 70 0.041
programmed cell death GO:0012501 392 0.040
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.040
single organism behavior GO:0044708 130 0.040
positive regulation of cellular protein metabolic process GO:0032270 167 0.039
Rat
defense response GO:0006952 194 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.038
cellular response to hormone stimulus GO:0032870 247 0.037
Rat
response to alkaloid GO:0043279 132 0.037
positive regulation of protein phosphorylation GO:0001934 135 0.037
Rat
cellular response to organic cyclic compound GO:0071407 202 0.037
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.037
Rat
reproduction GO:0000003 245 0.036
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.036
negative regulation of cell communication GO:0010648 158 0.036
alcohol metabolic process GO:0006066 77 0.036
multicellular organism reproduction GO:0032504 233 0.036
regulation of hormone secretion GO:0046883 106 0.036
anion transport GO:0006820 178 0.036
ion homeostasis GO:0050801 212 0.035
regulation of intracellular signal transduction GO:1902531 218 0.035
Rat
inflammatory response GO:0006954 150 0.034
positive regulation of phosphorus metabolic process GO:0010562 262 0.034
Rat
regulation of multicellular organismal development GO:2000026 376 0.034
Rat
positive regulation of mapk cascade GO:0043410 92 0.034
Rat
localization of cell GO:0051674 202 0.034
transmembrane transport GO:0055085 412 0.034
behavior GO:0007610 205 0.034
regulation of cell differentiation GO:0045595 320 0.033
multi organism reproductive process GO:0044703 262 0.033
positive regulation of biosynthetic process GO:0009891 319 0.033
negative regulation of programmed cell death GO:0043069 183 0.033
organic anion transport GO:0015711 132 0.032
aging GO:0007568 241 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.032
cellular response to stress GO:0033554 269 0.032
Rat
regulation of ion transport GO:0043269 245 0.032
positive regulation of rna metabolic process GO:0051254 203 0.032
cellular ketone metabolic process GO:0042180 51 0.031
enzyme linked receptor protein signaling pathway GO:0007167 116 0.031
protein oligomerization GO:0051259 191 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
positive regulation of transport GO:0051050 245 0.029
anterior posterior pattern specification GO:0009952 1 0.029
regulation of neurogenesis GO:0050767 247 0.029
negative regulation of biosynthetic process GO:0009890 168 0.029
cell motility GO:0048870 202 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
negative regulation of gene expression GO:0010629 199 0.027
cytosolic calcium ion homeostasis GO:0051480 140 0.027
single organism reproductive process GO:0044702 297 0.027
Human Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
circadian rhythm GO:0007623 88 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.026
regulation of kinase activity GO:0043549 117 0.026
Rat
reproductive process GO:0022414 372 0.026
Human Rat
developmental process involved in reproduction GO:0003006 159 0.025
Human Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
response to inorganic substance GO:0010035 377 0.025
Rat
response to corticosteroid GO:0031960 235 0.025
Rat
response to decreased oxygen levels GO:0036293 237 0.025
response to extracellular stimulus GO:0009991 380 0.025
Rat
cognition GO:0050890 92 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.024
Rat
regulation of anatomical structure size GO:0090066 135 0.024
Rat
response to nutrient levels GO:0031667 370 0.024
Rat
regulation of programmed cell death GO:0043067 341 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.024
skeletal system development GO:0001501 41 0.024
Human
cellular component biogenesis GO:0044085 368 0.024
oxoacid metabolic process GO:0043436 290 0.024
protein complex biogenesis GO:0070271 263 0.023
regulation of nervous system development GO:0051960 264 0.023
cation transmembrane transport GO:0098655 263 0.023
organic hydroxy compound metabolic process GO:1901615 115 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
positive regulation of protein metabolic process GO:0051247 178 0.022
Rat
neuron development GO:0048666 286 0.022
Rat
positive regulation of molecular function GO:0044093 230 0.022
Rat
non canonical wnt signaling pathway GO:0035567 3 0.022
Rat
positive regulation of protein modification process GO:0031401 142 0.022
Rat
cellular cation homeostasis GO:0030003 180 0.021
cation homeostasis GO:0055080 195 0.021
protein tetramerization GO:0051262 38 0.021
negative regulation of secretion GO:0051048 82 0.021
glutamate secretion GO:0014047 19 0.021
response to glucocorticoid GO:0051384 223 0.021
Rat
response to estradiol GO:0032355 164 0.021
Rat
regulation of molecular function GO:0065009 398 0.021
Rat
response to estrogen GO:0043627 232 0.020
Rat
response to acid chemical GO:0001101 222 0.020
Rat
cellular response to growth factor stimulus GO:0071363 162 0.020
regulation of cell motility GO:2000145 131 0.020
regulation of homeostatic process GO:0032844 101 0.020
reproductive structure development GO:0048608 128 0.020
Human Rat
steroid metabolic process GO:0008202 73 0.020
development of primary sexual characteristics GO:0045137 107 0.020
Human
positive regulation of cell differentiation GO:0045597 217 0.019
regulation of immune system process GO:0002682 123 0.019
hormone transport GO:0009914 121 0.019
single organism intracellular transport GO:1902582 166 0.019
neuron projection morphogenesis GO:0048812 122 0.019
Rat
cell growth GO:0016049 104 0.019
positive regulation of hormone secretion GO:0046887 65 0.019
acid secretion GO:0046717 48 0.019
positive regulation of secretion GO:0051047 140 0.019
regulation of cell proliferation GO:0042127 359 0.018
Rat
peptidyl amino acid modification GO:0018193 126 0.018
response to oxygen levels GO:0070482 265 0.018
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
eye morphogenesis GO:0048592 4 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.018
negative regulation of transport GO:0051051 136 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
locomotory behavior GO:0007626 15 0.018
regulation of catalytic activity GO:0050790 304 0.018
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
response to electrical stimulus GO:0051602 56 0.018
cellular response to acid chemical GO:0071229 75 0.018
Rat
regulation of cell development GO:0060284 263 0.018
ensheathment of neurons GO:0007272 40 0.018
positive regulation of nervous system development GO:0051962 178 0.017
regulation of neuron differentiation GO:0045664 208 0.017
locomotor rhythm GO:0045475 1 0.017
macromolecular complex assembly GO:0065003 273 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
dicarboxylic acid transport GO:0006835 34 0.017
response to glucose GO:0009749 136 0.016
signal release GO:0023061 145 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
negative regulation of hormone secretion GO:0046888 46 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
secretion GO:0046903 307 0.016
response to hexose GO:0009746 144 0.016
head development GO:0060322 247 0.016
Human
cell cell signaling GO:0007267 335 0.016
glutamate receptor signaling pathway GO:0007215 43 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
positive regulation of peptide hormone secretion GO:0090277 50 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.015
ion transmembrane transport GO:0034220 365 0.015
respiratory system development GO:0060541 45 0.015
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.015
protein complex assembly GO:0006461 263 0.015
multicellular organismal signaling GO:0035637 44 0.015
eye development GO:0001654 50 0.015
positive regulation of cell communication GO:0010647 271 0.015
Human Rat
neuron apoptotic process GO:0051402 88 0.015
gonad development GO:0008406 104 0.015
Human
positive regulation of developmental process GO:0051094 283 0.015
insulin like growth factor receptor signaling pathway GO:0048009 3 0.014
positive regulation of blood circulation GO:1903524 65 0.014
tissue development GO:0009888 252 0.014
Human Rat
small molecule biosynthetic process GO:0044283 124 0.014
ovulation cycle GO:0042698 67 0.014
intracellular transport GO:0046907 185 0.014
lipid storage GO:0019915 1 0.014
positive regulation of protein kinase activity GO:0045860 73 0.014
Rat
sequestering of metal ion GO:0051238 9 0.014
response to purine containing compound GO:0014074 126 0.014
response to monosaccharide GO:0034284 159 0.014
cytoplasmic transport GO:0016482 115 0.014
cell migration GO:0016477 197 0.013
negative regulation of secretion by cell GO:1903531 72 0.013
regulation of response to stress GO:0080134 126 0.013
Rat
maintenance of location GO:0051235 17 0.013
locomotory exploration behavior GO:0035641 1 0.013
regulation of lipid biosynthetic process GO:0046890 38 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.013
spermatogenesis GO:0007283 99 0.013
response to heat GO:0009408 60 0.013
regulation of ion homeostasis GO:2000021 63 0.013
cell projection morphogenesis GO:0048858 123 0.013
Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.013
response to mechanical stimulus GO:0009612 134 0.013
response to temperature stimulus GO:0009266 94 0.013
positive regulation of kinase activity GO:0033674 77 0.013
Rat
circulatory system process GO:0003013 183 0.012
protein complex subunit organization GO:0071822 302 0.012
regulation of transferase activity GO:0051338 123 0.012
Rat
regulation of receptor activity GO:0010469 29 0.012
amide transport GO:0042886 105 0.012
regulation of cellular component movement GO:0051270 150 0.012
response to carbohydrate GO:0009743 183 0.012
nucleotide metabolic process GO:0009117 279 0.012
cellular response to retinoic acid GO:0071300 27 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
Rat
regulation of amino acid transport GO:0051955 25 0.012
blood circulation GO:0008015 183 0.012
memory GO:0007613 54 0.012
vascular process in circulatory system GO:0003018 96 0.012
response to hypoxia GO:0001666 231 0.012
negative regulation of dopamine secretion GO:0033602 4 0.012
response to growth factor GO:0070848 189 0.012
regulation of peptide transport GO:0090087 87 0.011
exploration behavior GO:0035640 1 0.011
retina morphogenesis in camera type eye GO:0060042 1 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
cell morphogenesis GO:0000902 142 0.011
Rat
protein heterooligomerization GO:0051291 89 0.011
actin filament based process GO:0030029 86 0.011
positive regulation of cell development GO:0010720 176 0.011
organ morphogenesis GO:0009887 75 0.011
Rat
phasic smooth muscle contraction GO:0014821 3 0.011
neuron projection development GO:0031175 273 0.011
Rat
organophosphate metabolic process GO:0019637 370 0.011
positive regulation of peptide secretion GO:0002793 52 0.011
response to osmotic stress GO:0006970 42 0.011
male gamete generation GO:0048232 99 0.011
positive regulation of immune system process GO:0002684 90 0.011
transmission of nerve impulse GO:0019226 42 0.011
cellular response to lipid GO:0071396 201 0.011
Rat
neuronal action potential GO:0019228 35 0.011
negative regulation of rna metabolic process GO:0051253 123 0.010
positive regulation of homeostatic process GO:0032846 49 0.010
peptidyl tyrosine modification GO:0018212 72 0.010
regulation of growth GO:0040008 105 0.010
carbohydrate homeostasis GO:0033500 75 0.010
multi multicellular organism process GO:0044706 138 0.010
camera type eye morphogenesis GO:0048593 2 0.010
endocrine process GO:0050886 32 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010

Wnt2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.036
disease of anatomical entity DOID:7 0 0.036