Rattus norvegicus

0 known processes

Xpnpep2

X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound

Xpnpep2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 295 0.190
cation transmembrane transport GO:0098655 263 0.166
organic acid metabolic process GO:0006082 292 0.141
catabolic process GO:0009056 351 0.133
single organism biosynthetic process GO:0044711 342 0.124
inorganic ion transmembrane transport GO:0098660 229 0.113
oxoacid metabolic process GO:0043436 290 0.107
alpha amino acid metabolic process GO:1901605 71 0.100
carboxylic acid metabolic process GO:0019752 289 0.099
aromatic compound catabolic process GO:0019439 168 0.094
lipid metabolic process GO:0006629 283 0.087
cation transport GO:0006812 382 0.087
cellular response to endogenous stimulus GO:0071495 377 0.082
ion transmembrane transport GO:0034220 365 0.082
single organism catabolic process GO:0044712 283 0.080
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.078
organic substance catabolic process GO:1901575 316 0.076
single organism reproductive process GO:0044702 297 0.076
organonitrogen compound biosynthetic process GO:1901566 167 0.074
tissue development GO:0009888 252 0.073
transmembrane transport GO:0055085 412 0.071
regulation of hormone levels GO:0010817 187 0.066
organophosphate metabolic process GO:0019637 370 0.061
nucleobase containing small molecule metabolic process GO:0055086 316 0.059
response to insulin GO:0032868 133 0.059
small molecule catabolic process GO:0044282 59 0.059
cellular component biogenesis GO:0044085 368 0.059
coenzyme metabolic process GO:0006732 86 0.057
carboxylic acid transport GO:0046942 115 0.056
chemical homeostasis GO:0048878 292 0.053
organic hydroxy compound metabolic process GO:1901615 115 0.053
monocarboxylic acid metabolic process GO:0032787 152 0.052
organic acid biosynthetic process GO:0016053 83 0.052
regulation of phosphorus metabolic process GO:0051174 349 0.051
organic cyclic compound catabolic process GO:1901361 175 0.051
choline transport GO:0015871 4 0.051
glutathione transport GO:0034635 2 0.050
antibiotic transport GO:0042891 2 0.050
cellular lipid metabolic process GO:0044255 208 0.049
response to oxygen levels GO:0070482 265 0.048
amino acid transport GO:0006865 70 0.047
organic acid transport GO:0015849 116 0.047
anion transport GO:0006820 178 0.047
diterpenoid metabolic process GO:0016101 33 0.046
brain development GO:0007420 247 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.045
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.044
carboxylic acid catabolic process GO:0046395 49 0.044
cellular hormone metabolic process GO:0034754 49 0.042
drug transmembrane transport GO:0006855 13 0.042
purine containing compound metabolic process GO:0072521 253 0.042
cholesterol homeostasis GO:0042632 3 0.042
macromolecular complex subunit organization GO:0043933 339 0.041
response to alkaloid GO:0043279 132 0.041
protein complex subunit organization GO:0071822 302 0.041
vitamin a metabolic process GO:0006776 2 0.041
isoprenoid metabolic process GO:0006720 45 0.040
blood circulation GO:0008015 183 0.039
sterol homeostasis GO:0055092 3 0.039
behavioral response to nicotine GO:0035095 2 0.039
cell adhesion GO:0007155 110 0.039
response to hypoxia GO:0001666 231 0.037
central nervous system development GO:0007417 311 0.037
organic anion transport GO:0015711 132 0.036
homeostatic process GO:0042592 331 0.036
response to ethanol GO:0045471 162 0.036
inorganic cation transmembrane transport GO:0098662 202 0.036
organophosphate biosynthetic process GO:0090407 143 0.035
ribose phosphate metabolic process GO:0019693 235 0.035
nucleotide metabolic process GO:0009117 279 0.035
neurological system process GO:0050877 219 0.034
cellular component assembly GO:0022607 360 0.034
purine ribonucleotide metabolic process GO:0009150 227 0.034
sexual reproduction GO:0019953 148 0.034
multicellular organism reproduction GO:0032504 233 0.034
cellular response to hormone stimulus GO:0032870 247 0.034
cellular response to stress GO:0033554 269 0.034
nucleoside phosphate metabolic process GO:0006753 283 0.034
response to peptide GO:1901652 292 0.033
purine ribonucleotide catabolic process GO:0009154 136 0.033
programmed cell death GO:0012501 392 0.033
cofactor metabolic process GO:0051186 95 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
regulation of lipid metabolic process GO:0019216 68 0.032
biological adhesion GO:0022610 110 0.032
response to extracellular stimulus GO:0009991 380 0.032
positive regulation of biosynthetic process GO:0009891 319 0.032
regulation of nervous system development GO:0051960 264 0.031
response to metal ion GO:0010038 253 0.031
retinal metabolic process GO:0042574 3 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
generation of precursor metabolites and energy GO:0006091 62 0.031
organonitrogen compound catabolic process GO:1901565 179 0.030
glycosyl compound metabolic process GO:1901657 182 0.030
multi organism reproductive process GO:0044703 262 0.030
reproduction GO:0000003 245 0.030
macromolecular complex assembly GO:0065003 273 0.030
positive regulation of developmental process GO:0051094 283 0.030
locomotion GO:0040011 237 0.030
carnitine transport GO:0015879 1 0.030
tripeptide transport GO:0042939 2 0.029
regulation of locomotion GO:0040012 148 0.028
regulation of cell development GO:0060284 263 0.028
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.028
negative regulation of nervous system development GO:0051961 79 0.028
negative regulation of neuron differentiation GO:0045665 62 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
organic acid catabolic process GO:0016054 49 0.028
purine nucleotide metabolic process GO:0006163 229 0.027
regulation of neurogenesis GO:0050767 247 0.027
purine nucleoside metabolic process GO:0042278 169 0.027
cellular response to nitrogen compound GO:1901699 210 0.027
apoptotic process GO:0006915 381 0.027
regulation of neuron projection development GO:0010975 161 0.027
response to decreased oxygen levels GO:0036293 237 0.027
response to growth factor GO:0070848 189 0.027
carbohydrate metabolic process GO:0005975 130 0.027
ribonucleotide metabolic process GO:0009259 231 0.026
regulation of nucleotide metabolic process GO:0006140 117 0.026
anion transmembrane transport GO:0098656 77 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
sodium independent organic anion transport GO:0043252 2 0.026
small molecule biosynthetic process GO:0044283 124 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
protein complex assembly GO:0006461 263 0.025
vitamin d receptor signaling pathway GO:0070561 1 0.025
terpenoid metabolic process GO:0006721 37 0.025
positive regulation of phagocytosis engulfment GO:0060100 4 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
regulation of blood pressure GO:0008217 83 0.024
response to toxic substance GO:0009636 133 0.024
response to peptide hormone GO:0043434 278 0.024
cation homeostasis GO:0055080 195 0.024
cellular response to vitamin e GO:0071306 3 0.024
sulfur compound metabolic process GO:0006790 70 0.024
nucleoside metabolic process GO:0009116 179 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
purine nucleotide catabolic process GO:0006195 136 0.024
lipid biosynthetic process GO:0008610 128 0.024
steroid metabolic process GO:0008202 73 0.023
positive regulation of nervous system development GO:0051962 178 0.023
positive regulation of cellular component movement GO:0051272 102 0.023
regulation of signal transduction GO:0009966 318 0.023
cellular nitrogen compound catabolic process GO:0044270 163 0.023
proteolysis GO:0006508 175 0.023
Rat Fly
aging GO:0007568 241 0.023
response to molecule of bacterial origin GO:0002237 194 0.023
regulation of anatomical structure size GO:0090066 135 0.022
response to carbohydrate GO:0009743 183 0.022
carboxylic acid biosynthetic process GO:0046394 83 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
response to acid chemical GO:0001101 222 0.022
negative regulation of innate immune response GO:0045824 4 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.021
cellular response to peptide GO:1901653 133 0.021
cellular chemical homeostasis GO:0055082 247 0.021
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.021
protein homooligomerization GO:0051260 91 0.021
alpha amino acid catabolic process GO:1901606 20 0.021
metal ion transport GO:0030001 289 0.021
cell morphogenesis GO:0000902 142 0.021
cellular response to oxygen levels GO:0071453 60 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
protein complex biogenesis GO:0070271 263 0.021
oligopeptide transport GO:0006857 4 0.020
reproductive process GO:0022414 372 0.020
nucleoside triphosphate metabolic process GO:0009141 144 0.020
liver development GO:0001889 90 0.020
cellular amine metabolic process GO:0044106 38 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
intracellular signal transduction GO:0035556 314 0.020
organophosphate catabolic process GO:0046434 148 0.020
regulation of ion transport GO:0043269 245 0.020
muscle cell proliferation GO:0033002 84 0.019
pancreatic stellate cell proliferation GO:0072343 2 0.019
female pregnancy GO:0007565 122 0.019
regulation of catalytic activity GO:0050790 304 0.019
cellular amino acid catabolic process GO:0009063 21 0.019
cellular ketone metabolic process GO:0042180 51 0.019
head development GO:0060322 247 0.019
cyclic nucleotide metabolic process GO:0009187 80 0.019
positive regulation of signaling GO:0023056 270 0.018
regulation of cell differentiation GO:0045595 320 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
response to molecule of fungal origin GO:0002238 3 0.018
serine family amino acid metabolic process GO:0009069 12 0.018
response to monosaccharide GO:0034284 159 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
synaptic transmission GO:0007268 235 0.018
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
neuron development GO:0048666 286 0.018
oxidation reduction process GO:0055114 304 0.018
negative regulation of collagen biosynthetic process GO:0032966 4 0.018
purine ribonucleotide biosynthetic process GO:0009152 81 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
response to nicotine GO:0035094 51 0.017
response to glucocorticoid GO:0051384 223 0.017
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
response to cocaine GO:0042220 39 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
heterocycle catabolic process GO:0046700 167 0.017
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
neurotransmitter transport GO:0006836 42 0.017
quaternary ammonium group transport GO:0015697 6 0.017
retinoid metabolic process GO:0001523 24 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
positive regulation of gene expression GO:0010628 244 0.017
ion homeostasis GO:0050801 212 0.017
metal ion homeostasis GO:0055065 186 0.017
amino acid betaine transport GO:0015838 1 0.017
anatomical structure morphogenesis GO:0009653 298 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.016
monosaccharide metabolic process GO:0005996 61 0.016
regulation of molecular function GO:0065009 398 0.016
neuron projection development GO:0031175 273 0.016
regulation of response to stress GO:0080134 126 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
smooth muscle cell proliferation GO:0048659 77 0.016
organic hydroxy compound transport GO:0015850 77 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
cellular response to metal ion GO:0071248 55 0.016
purine nucleoside triphosphate catabolic process GO:0009146 122 0.016
response to ketone GO:1901654 182 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
positive regulation of cell development GO:0010720 176 0.016
response to nutrient GO:0007584 248 0.016
behavior GO:0007610 205 0.016
regulation of apoptotic process GO:0042981 335 0.016
cellular lipid catabolic process GO:0044242 37 0.015
regulation of cellular component organization GO:0051128 368 0.015
macromolecule localization GO:0033036 252 0.015
response to estradiol GO:0032355 164 0.015
regulation of cell motility GO:2000145 131 0.015
response to temperature stimulus GO:0009266 94 0.015
nucleic acid templated transcription GO:0097659 379 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
growth GO:0040007 165 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
positive regulation of molecular function GO:0044093 230 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
hormone metabolic process GO:0042445 69 0.015
intestinal absorption GO:0050892 3 0.015
positive regulation of cell death GO:0010942 184 0.015
amine metabolic process GO:0009308 38 0.015
regulation of cell projection organization GO:0031344 175 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
naphthalene containing compound metabolic process GO:0090420 2 0.015
cell growth GO:0016049 104 0.015
dopamine transport GO:0015872 18 0.015
cell projection organization GO:0030030 302 0.015
cellular homeostasis GO:0019725 252 0.015
cell cell signaling GO:0007267 335 0.015
small gtpase mediated signal transduction GO:0007264 36 0.014
cellular component movement GO:0006928 248 0.014
cellular component morphogenesis GO:0032989 155 0.014
response to purine containing compound GO:0014074 126 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
acetyl coa metabolic process GO:0006084 17 0.014
response to ammonium ion GO:0060359 71 0.014
monocarboxylic acid catabolic process GO:0072329 28 0.014
multi multicellular organism process GO:0044706 138 0.014
cellular ion homeostasis GO:0006873 184 0.014
nicotinamide nucleotide metabolic process GO:0046496 28 0.014
aromatic amino acid family catabolic process GO:0009074 7 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
monocarboxylic acid transport GO:0015718 52 0.014
response to amine GO:0014075 46 0.014
nucleotide catabolic process GO:0009166 139 0.014
cellular modified amino acid metabolic process GO:0006575 61 0.014
lipid transport GO:0006869 61 0.014
spermatogenesis GO:0007283 99 0.014
mrna transcription GO:0009299 2 0.014
response to vitamin e GO:0033197 24 0.014
response to metformin GO:1901558 1 0.014
regulation of cell growth GO:0001558 85 0.014
multicellular organism growth GO:0035264 1 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
response to mechanical stimulus GO:0009612 134 0.013
naphthalene metabolic process GO:0018931 2 0.013
organic hydroxy compound biosynthetic process GO:1901617 51 0.013
regulation of programmed cell death GO:0043067 341 0.013
hexose metabolic process GO:0019318 58 0.013
sulfur amino acid metabolic process GO:0000096 9 0.013
response to inorganic substance GO:0010035 377 0.013
gamete generation GO:0007276 124 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
lipid oxidation GO:0034440 30 0.013
negative regulation of developmental process GO:0051093 125 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
regeneration GO:0031099 163 0.013
gliogenesis GO:0042063 93 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
bile acid biosynthetic process GO:0006699 3 0.013
cyclic nucleotide biosynthetic process GO:0009190 63 0.013
regulation of membrane potential GO:0042391 110 0.013
circadian rhythm GO:0007623 88 0.013
developmental process involved in reproduction GO:0003006 159 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
toxin transport GO:1901998 3 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
fatty acid metabolic process GO:0006631 99 0.012
cellular response to lipid GO:0071396 201 0.012
cellular response to inorganic substance GO:0071241 65 0.012
response to vitamin GO:0033273 131 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
dicarboxylic acid metabolic process GO:0043648 42 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
lipid storage GO:0019915 1 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
regulation of lipid biosynthetic process GO:0046890 38 0.012
muscle system process GO:0003012 115 0.012
regulation of system process GO:0044057 208 0.012
modified amino acid transport GO:0072337 12 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
thioester metabolic process GO:0035383 28 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
inflammatory response GO:0006954 150 0.012
response to hyperoxia GO:0055093 45 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
phospholipid biosynthetic process GO:0008654 29 0.012
nucleoside catabolic process GO:0009164 126 0.012
learning or memory GO:0007611 90 0.012
alditol metabolic process GO:0019400 4 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
cell part morphogenesis GO:0032990 123 0.012
protein oligomerization GO:0051259 191 0.012
ras protein signal transduction GO:0007265 29 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
glycerolipid metabolic process GO:0046486 67 0.012
smooth muscle cell migration GO:0014909 36 0.012
transmission of nerve impulse GO:0019226 42 0.011
response to radiation GO:0009314 137 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
dendrite morphogenesis GO:0048813 43 0.011
muscle cell migration GO:0014812 36 0.011
regulation of neuron differentiation GO:0045664 208 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
phospholipid metabolic process GO:0006644 61 0.011
phasic smooth muscle contraction GO:0014821 3 0.011
regulation of immune response to tumor cell GO:0002837 3 0.011
chromosome segregation GO:0007059 2 0.011
response to corticosteroid GO:0031960 235 0.011
purine containing compound catabolic process GO:0072523 138 0.011
single organism behavior GO:0044708 130 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
single organism organelle organization GO:1902589 180 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
cellular macromolecule localization GO:0070727 122 0.011
endocytosis GO:0006897 84 0.011
proteoglycan metabolic process GO:0006029 3 0.011
inner medullary collecting duct development GO:0072061 1 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
response to nutrient levels GO:0031667 370 0.011
regulation of plasma lipoprotein particle levels GO:0097006 3 0.011
nitrogen compound transport GO:0071705 229 0.011
neuron death GO:0070997 127 0.011
monocarboxylic acid biosynthetic process GO:0072330 48 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.011
circulatory system development GO:0072359 134 0.011
fatty acid oxidation GO:0019395 29 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.011
response to osmotic stress GO:0006970 42 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.010
response to bacterium GO:0009617 200 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
cellular response to hypoxia GO:0071456 51 0.010
drug transport GO:0015893 18 0.010
maternal process involved in female pregnancy GO:0060135 38 0.010
neuron differentiation GO:0030182 368 0.010
response to activity GO:0014823 73 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
response to external biotic stimulus GO:0043207 221 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
phenol containing compound metabolic process GO:0018958 30 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
regulation of defense response GO:0031347 68 0.010

Xpnpep2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
musculoskeletal system disease DOID:17 0 0.024
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.017
inherited metabolic disorder DOID:655 0 0.016
connective tissue disease DOID:65 0 0.014