Rattus norvegicus

0 known processes

Zp3

zona pellucida glycoprotein 3 (sperm receptor)

(Aliases: Zp-3)

Zp3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to hormone stimulus GO:0032870 247 0.445
response to extracellular stimulus GO:0009991 380 0.432
cellular response to endogenous stimulus GO:0071495 377 0.355
response to nutrient levels GO:0031667 370 0.349
response to carbohydrate GO:0009743 183 0.276
response to decreased oxygen levels GO:0036293 237 0.233
chemical homeostasis GO:0048878 292 0.203
response to inorganic substance GO:0010035 377 0.191
cellular chemical homeostasis GO:0055082 247 0.181
cellular response to oxygen containing compound GO:1901701 386 0.174
single organism biosynthetic process GO:0044711 342 0.167
Mouse
apoptotic process GO:0006915 381 0.166
homeostatic process GO:0042592 331 0.160
cellular homeostasis GO:0019725 252 0.153
response to purine containing compound GO:0014074 126 0.151
response to oxygen levels GO:0070482 265 0.135
cellular response to lipid GO:0071396 201 0.131
response to estrogen GO:0043627 232 0.119
response to organophosphorus GO:0046683 102 0.112
programmed cell death GO:0012501 392 0.110
regulation of apoptotic process GO:0042981 335 0.109
cellular response to external stimulus GO:0071496 118 0.104
negative regulation of apoptotic process GO:0043066 181 0.104
response to metal ion GO:0010038 253 0.100
neurological system process GO:0050877 219 0.099
regulation of cell proliferation GO:0042127 359 0.099
Mouse
negative regulation of cell death GO:0060548 229 0.098
response to hypoxia GO:0001666 231 0.098
response to peptide hormone GO:0043434 278 0.096
protein phosphorylation GO:0006468 345 0.091
Human
cation transmembrane transport GO:0098655 263 0.091
Human Mouse
regulation of anatomical structure size GO:0090066 135 0.090
cation transport GO:0006812 382 0.087
Human Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.086
Mouse
oxoacid metabolic process GO:0043436 290 0.085
cellular response to stress GO:0033554 269 0.083
regeneration GO:0031099 163 0.082
protein complex biogenesis GO:0070271 263 0.081
response to estradiol GO:0032355 164 0.079
macromolecular complex assembly GO:0065003 273 0.078
catabolic process GO:0009056 351 0.078
response to axon injury GO:0048678 59 0.076
protein complex assembly GO:0006461 263 0.073
response to camp GO:0051591 91 0.073
macromolecular complex subunit organization GO:0043933 339 0.073
response to acid chemical GO:0001101 222 0.072
negative regulation of programmed cell death GO:0043069 183 0.071
cellular response to organonitrogen compound GO:0071417 197 0.069
multi organism reproductive process GO:0044703 262 0.069
Human Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.068
Human Mouse
response to glucocorticoid GO:0051384 223 0.066
regulation of phosphate metabolic process GO:0019220 349 0.065
Human Mouse
response to reactive oxygen species GO:0000302 120 0.062
regulation of programmed cell death GO:0043067 341 0.061
regulation of system process GO:0044057 208 0.060
protein oligomerization GO:0051259 191 0.060
response to heat GO:0009408 60 0.060
cellular response to nitrogen compound GO:1901699 210 0.059
response to nutrient GO:0007584 248 0.059
signal release GO:0023061 145 0.058
cell cell signaling GO:0007267 335 0.058
response to cytokine GO:0034097 215 0.058
neuron projection development GO:0031175 273 0.055
response to hydrogen peroxide GO:0042542 89 0.055
regulation of kinase activity GO:0043549 117 0.054
Human
regulation of response to stress GO:0080134 126 0.053
Mouse
multicellular organism reproduction GO:0032504 233 0.053
Mouse
transmembrane transport GO:0055085 412 0.053
Human Mouse
cellular catabolic process GO:0044248 295 0.052
regulation of secretion by cell GO:1903530 208 0.051
Human Mouse
cellular component biogenesis GO:0044085 368 0.051
cellular response to insulin stimulus GO:0032869 81 0.051
muscle system process GO:0003012 115 0.051
positive regulation of molecular function GO:0044093 230 0.051
Human
amine metabolic process GO:0009308 38 0.051
development of primary sexual characteristics GO:0045137 107 0.050
Mouse
actin filament based process GO:0030029 86 0.049
secretion GO:0046903 307 0.049
Human Mouse
aging GO:0007568 241 0.049
cardiovascular system development GO:0072358 134 0.048
cofactor biosynthetic process GO:0051188 28 0.047
response to increased oxygen levels GO:0036296 45 0.047
response to ketone GO:1901654 182 0.047
organic acid metabolic process GO:0006082 292 0.046
response to insulin GO:0032868 133 0.045
carboxylic acid metabolic process GO:0019752 289 0.045
locomotion GO:0040011 237 0.045
Mouse
response to growth factor GO:0070848 189 0.045
response to ethanol GO:0045471 162 0.045
cellular ketone metabolic process GO:0042180 51 0.044
cellular response to organic cyclic compound GO:0071407 202 0.043
response to oxidative stress GO:0006979 186 0.043
cellular amine metabolic process GO:0044106 38 0.043
regulation of cellular amine metabolic process GO:0033238 8 0.042
response to glucose GO:0009749 136 0.041
response to hexose GO:0009746 144 0.041
anatomical structure morphogenesis GO:0009653 298 0.041
Mouse
dna metabolic process GO:0006259 96 0.040
positive regulation of developmental process GO:0051094 283 0.038
Mouse
cellular calcium ion homeostasis GO:0006874 160 0.037
cellular cation homeostasis GO:0030003 180 0.037
response to vitamin GO:0033273 131 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
cellular response to peptide GO:1901653 133 0.036
vascular process in circulatory system GO:0003018 96 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
Mouse
neuron death GO:0070997 127 0.035
circulatory system development GO:0072359 134 0.034
gonad development GO:0008406 104 0.034
Mouse
brain renin angiotensin system GO:0002035 3 0.034
multicellular organismal reproductive process GO:0048609 233 0.034
Mouse
cytoskeleton organization GO:0007010 111 0.033
positive regulation of transport GO:0051050 245 0.032
Human Mouse
signal transduction by phosphorylation GO:0023014 144 0.032
cellular response to alcohol GO:0097306 87 0.032
neuron development GO:0048666 286 0.031
response to retinoic acid GO:0032526 63 0.031
cation homeostasis GO:0055080 195 0.031
response to wounding GO:0009611 254 0.031
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
Mouse
response to mechanical stimulus GO:0009612 134 0.030
cellular component assembly GO:0022607 360 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
cellular ion homeostasis GO:0006873 184 0.030
reproductive system development GO:0061458 128 0.030
Mouse
single organism reproductive process GO:0044702 297 0.030
Human Mouse
defense response GO:0006952 194 0.029
Mouse
regulation of transferase activity GO:0051338 123 0.029
Human
blood circulation GO:0008015 183 0.029
regulation of neurogenesis GO:0050767 247 0.029
regulation of nervous system development GO:0051960 264 0.029
glucose homeostasis GO:0042593 75 0.029
regulation of secretion GO:0051046 224 0.028
Human Mouse
peptide secretion GO:0002790 86 0.028
response to hyperoxia GO:0055093 45 0.028
calcium ion homeostasis GO:0055074 162 0.028
epithelial cell differentiation GO:0030855 71 0.028
response to lipopolysaccharide GO:0032496 191 0.028
positive regulation of response to stimulus GO:0048584 285 0.027
Human Mouse
protein homooligomerization GO:0051260 91 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
Mouse
hormone transport GO:0009914 121 0.027
regulation of hormone levels GO:0010817 187 0.027
cellular response to steroid hormone stimulus GO:0071383 93 0.027
ameboidal type cell migration GO:0001667 26 0.026
organic acid transport GO:0015849 116 0.026
protein complex subunit organization GO:0071822 302 0.026
regulation of vasoconstriction GO:0019229 44 0.026
response to corticosteroid GO:0031960 235 0.025
cellular metal ion homeostasis GO:0006875 172 0.025
cellular response to growth factor stimulus GO:0071363 162 0.025
positive regulation of angiogenesis GO:0045766 28 0.025
regulation of cellular component movement GO:0051270 150 0.025
Mouse
cytosolic calcium ion homeostasis GO:0051480 140 0.024
behavior GO:0007610 205 0.024
cognition GO:0050890 92 0.024
cell matrix adhesion GO:0007160 19 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
Human Mouse
cellular response to hexose stimulus GO:0071331 65 0.024
proteolysis GO:0006508 175 0.023
gamete generation GO:0007276 124 0.023
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
sexual reproduction GO:0019953 148 0.023
Human Mouse
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
negative regulation of molecular function GO:0044092 133 0.023
vasoconstriction GO:0042310 54 0.023
actin cytoskeleton organization GO:0030036 73 0.023
regulation of dna metabolic process GO:0051052 60 0.022
intracellular signal transduction GO:0035556 314 0.022
Human Mouse
positive regulation of phosphorylation GO:0042327 177 0.022
Human
negative regulation of gene expression GO:0010629 199 0.022
Mouse
response to toxic substance GO:0009636 133 0.022
regulation of blood circulation GO:1903522 110 0.021
response to nicotine GO:0035094 51 0.021
micturition GO:0060073 4 0.021
immune system process GO:0002376 204 0.021
Human Mouse
positive regulation of nervous system development GO:0051962 178 0.021
circulatory system process GO:0003013 183 0.021
regulation of cellular component organization GO:0051128 368 0.021
regulation of endocytosis GO:0030100 42 0.021
regulation of molecular function GO:0065009 398 0.021
Human
response to biotic stimulus GO:0009607 226 0.021
positive regulation of catalytic activity GO:0043085 184 0.020
Human
s shaped body morphogenesis GO:0072050 2 0.020
gland development GO:0048732 155 0.020
organelle organization GO:0006996 266 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.020
nitrogen compound transport GO:0071705 229 0.020
rna biosynthetic process GO:0032774 380 0.019
Mouse
response to transition metal nanoparticle GO:1990267 122 0.019
regulation of phosphorylation GO:0042325 248 0.019
Human
regulation of transcription dna templated GO:0006355 374 0.019
Mouse
cellular response to abiotic stimulus GO:0071214 85 0.019
hormone secretion GO:0046879 115 0.019
insecticide metabolic process GO:0017143 4 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
Human
reproduction GO:0000003 245 0.019
Human Mouse
positive regulation of cell proliferation GO:0008284 249 0.019
Mouse
leukocyte migration GO:0050900 38 0.019
Mouse
positive regulation of lipid kinase activity GO:0090218 2 0.019
carbohydrate homeostasis GO:0033500 75 0.018
response to other organism GO:0051707 220 0.018
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
Human
divalent inorganic cation homeostasis GO:0072507 165 0.018
ion homeostasis GO:0050801 212 0.018
regulation of actin filament based process GO:0032970 42 0.018
sex differentiation GO:0007548 113 0.018
Mouse
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.018
cell projection organization GO:0030030 302 0.018
cellular response to extracellular stimulus GO:0031668 73 0.018
axis specification GO:0009798 4 0.017
anatomical structure homeostasis GO:0060249 29 0.017
forebrain development GO:0030900 98 0.017
metal ion homeostasis GO:0055065 186 0.017
epithelial cell migration GO:0010631 19 0.017
regulation of cell motility GO:2000145 131 0.017
Mouse
positive regulation of hormone secretion GO:0046887 65 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
Human
secretion by cell GO:0032940 248 0.016
Human Mouse
tube development GO:0035295 89 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
Mouse
regulation of blood pressure GO:0008217 83 0.016
chemosensory behavior GO:0007635 2 0.016
response to starvation GO:0042594 59 0.016
developmental process involved in reproduction GO:0003006 159 0.016
Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
Human Mouse
cell part morphogenesis GO:0032990 123 0.016
cellular response to peptide hormone stimulus GO:0071375 120 0.016
central nervous system development GO:0007417 311 0.016
regulation of protein kinase activity GO:0045859 105 0.016
Human
regulation of intracellular signal transduction GO:1902531 218 0.015
Mouse
regulation of signal transduction GO:0009966 318 0.015
Mouse
transcription dna templated GO:0006351 377 0.015
Mouse
heart process GO:0003015 57 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
Human Mouse
smooth muscle cell proliferation GO:0048659 77 0.015
renal system development GO:0072001 67 0.015
positive regulation of cell migration GO:0030335 96 0.015
Mouse
cellular modified amino acid biosynthetic process GO:0042398 18 0.015
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.015
nucleic acid templated transcription GO:0097659 379 0.014
Mouse
comma shaped body morphogenesis GO:0072049 2 0.014
regulation of protein homodimerization activity GO:0043496 5 0.014
male gonad development GO:0008584 59 0.014
response to peptide GO:1901652 292 0.014
salivary gland development GO:0007431 3 0.014
regulation of membrane potential GO:0042391 110 0.014
organic substance catabolic process GO:1901575 316 0.014
tissue homeostasis GO:0001894 28 0.014
positive regulation of saliva secretion GO:0046878 3 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
Mouse
regulation of blood vessel size GO:0050880 89 0.014
developmental growth GO:0048589 100 0.014
Mouse
regulation of smooth muscle cell migration GO:0014910 36 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
Mouse
response to monosaccharide GO:0034284 159 0.014
positive regulation of cell communication GO:0010647 271 0.014
Mouse
cellular response to glucose stimulus GO:0071333 65 0.013
response to vitamin a GO:0033189 36 0.013
male sex differentiation GO:0046661 64 0.013
regulation of cytoskeleton organization GO:0051493 49 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
Mouse
positive regulation of peptide hormone secretion GO:0090277 50 0.013
single organism behavior GO:0044708 130 0.013
regulation of protein metabolic process GO:0051246 289 0.013
Human
response to gonadotropin GO:0034698 34 0.013
blood vessel development GO:0001568 69 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
rna metabolic process GO:0016070 406 0.013
Mouse
divalent inorganic cation transport GO:0072511 134 0.013
Human Mouse
regulation of epithelial cell proliferation GO:0050678 49 0.013
positive regulation of blood circulation GO:1903524 65 0.013
cell motility GO:0048870 202 0.012
Mouse
regulation of cell projection organization GO:0031344 175 0.012
metanephric s shaped body morphogenesis GO:0072284 2 0.012
regulation of ion transport GO:0043269 245 0.012
Human Mouse
organic hydroxy compound biosynthetic process GO:1901617 51 0.012
regulation of saliva secretion GO:0046877 3 0.012
organic hydroxy compound transport GO:0015850 77 0.012
positive regulation of kinase activity GO:0033674 77 0.012
Human
angiotensin mediated drinking behavior GO:0003051 2 0.012
reproductive process GO:0022414 372 0.012
Human Mouse
heart contraction GO:0060047 57 0.012
cellular response to oxidative stress GO:0034599 76 0.012
tissue development GO:0009888 252 0.012
multi multicellular organism process GO:0044706 138 0.012
response to alkaloid GO:0043279 132 0.012
cell migration GO:0016477 197 0.012
Mouse
response to activity GO:0014823 73 0.011
heart morphogenesis GO:0003007 3 0.011
vasomotion GO:1990029 1 0.011
rhythmic process GO:0048511 156 0.011
Mouse
peristalsis GO:0030432 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
regulation of homeostatic process GO:0032844 101 0.011
regulation of neuron differentiation GO:0045664 208 0.011
cellular response to oxygen levels GO:0071453 60 0.011
response to lead ion GO:0010288 33 0.011
cellular response to monosaccharide stimulus GO:0071326 67 0.011
positive regulation of locomotion GO:0040017 102 0.011
Mouse
vasculature development GO:0001944 70 0.011
axon regeneration GO:0031103 28 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
Mouse
neuron differentiation GO:0030182 368 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
Mouse
cellular response to gonadotropin stimulus GO:0071371 17 0.011
oxidation reduction process GO:0055114 304 0.011
cellular response to mechanical stimulus GO:0071260 48 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
Mouse
cellular response to fluid shear stress GO:0071498 4 0.011
head development GO:0060322 247 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
Mouse
monovalent inorganic cation homeostasis GO:0055067 36 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
Mouse
regulation of cellular component biogenesis GO:0044087 86 0.011
neural crest cell differentiation GO:0014033 2 0.011
response to radiation GO:0009314 137 0.011
steroid metabolic process GO:0008202 73 0.011
positive regulation of dna metabolic process GO:0051054 39 0.011
mitotic cell cycle phase transition GO:0044772 20 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
Mouse
cell communication by chemical coupling GO:0010643 2 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
saliva secretion GO:0046541 3 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
protein autophosphorylation GO:0046777 66 0.010
cellular glucose homeostasis GO:0001678 66 0.010
cellular component movement GO:0006928 248 0.010
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
single organism organelle organization GO:1902589 180 0.010
positive regulation of humoral immune response GO:0002922 2 0.010
Human
negative regulation of protein metabolic process GO:0051248 114 0.010
single organism catabolic process GO:0044712 283 0.010

Zp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038