Caenorhabditis elegans

152 known processes

sma-6 (CELE_C32D5.2)

Protein SMA-6

sma-6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sexual reproduction GO:0019953 546 0.928
Mouse Fly
multicellular organismal reproductive process GO:0048609 815 0.879
Mouse Rat Worm Fly
neuron projection guidance GO:0097485 82 0.878
Mouse Fly
single organism reproductive process GO:0044702 1196 0.873
Human Mouse Rat Fly
multicellular organism reproduction GO:0032504 819 0.861
Mouse Rat Worm Fly
apoptotic process GO:0006915 478 0.842
Human Mouse Rat
mapk cascade GO:0000165 31 0.842
Human
post embryonic development GO:0009791 2152 0.837
gamete generation GO:0007276 461 0.804
Mouse Fly
regulation of vulval development GO:0040028 248 0.760
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.751
Mouse Fly
single organism signaling GO:0044700 401 0.747
Human Zebrafish Mouse Rat Worm Fly
developmental process involved in reproduction GO:0003006 1165 0.745
cell development GO:0048468 696 0.727
Human Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.724
response to external stimulus GO:0009605 289 0.724
organic substance catabolic process GO:1901575 294 0.721
nucleic acid metabolic process GO:0090304 299 0.720
regulation of signaling GO:0023051 172 0.717
Human Zebrafish Mouse Rat Worm Fly
signal transduction GO:0007165 317 0.715
Human Zebrafish Mouse Rat Worm Fly
organ development GO:0048513 1102 0.713
Human Zebrafish Mouse Rat Fly
aromatic compound biosynthetic process GO:0019438 192 0.712
regulation of nematode larval development GO:0061062 260 0.699
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.698
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.690
neuron development GO:0048666 199 0.650
Mouse Fly
signaling GO:0023052 401 0.644
Human Zebrafish Mouse Rat Worm Fly
germ cell development GO:0007281 351 0.644
Mouse Fly
embryonic morphogenesis GO:0048598 152 0.616
Human Zebrafish Mouse Fly
multi organism reproductive process GO:0044703 867 0.615
Human Mouse Rat Worm Fly
female gamete generation GO:0007292 254 0.611
Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.611
vulval development GO:0040025 333 0.606
positive regulation of organ growth GO:0046622 4 0.602
embryo development GO:0009790 3052 0.601
Human Zebrafish Mouse Rat Fly
positive regulation of cellular metabolic process GO:0031325 178 0.599
nucleobase containing compound biosynthetic process GO:0034654 184 0.593
post embryonic organ development GO:0048569 336 0.589
Fly
cell morphogenesis GO:0000902 163 0.581
negative regulation of biological process GO:0048519 567 0.577
Human Zebrafish Mouse Rat Worm Fly
regulation of cellular metabolic process GO:0031323 305 0.577
neuron projection morphogenesis GO:0048812 114 0.565
Mouse Fly
neuron differentiation GO:0030182 217 0.529
Mouse Fly
epithelium development GO:0060429 68 0.528
Human Zebrafish Mouse Rat Fly
regulation of post embryonic development GO:0048580 260 0.521
sex differentiation GO:0007548 909 0.520
nervous system development GO:0007399 253 0.518
Zebrafish Mouse Rat Fly
neuron projection development GO:0031175 187 0.515
Mouse Fly
cellular component morphogenesis GO:0032989 318 0.509
development of primary sexual characteristics GO:0045137 840 0.498
Mouse Rat
single organism organelle organization GO:1902589 501 0.496
Fly
enzyme linked receptor protein signaling pathway GO:0007167 50 0.490
Human Zebrafish Mouse Rat Worm Fly
gastrulation GO:0007369 58 0.484
Zebrafish Mouse Fly
axon development GO:0061564 163 0.483
Mouse Fly
heterocycle biosynthetic process GO:0018130 187 0.483
tissue morphogenesis GO:0048729 65 0.479
Human Zebrafish Mouse Fly
cell motility GO:0048870 313 0.473
Human Zebrafish Mouse Fly
organophosphate metabolic process GO:0019637 125 0.462
cell surface receptor signaling pathway GO:0007166 149 0.462
Human Zebrafish Mouse Rat Worm Fly
positive regulation of intracellular signal transduction GO:1902533 24 0.461
Human
negative regulation of vulval development GO:0040027 206 0.456
cellular macromolecule biosynthetic process GO:0034645 247 0.451
cell projection organization GO:0030030 231 0.450
Mouse Fly
cellular lipid metabolic process GO:0044255 40 0.450
regulation of gene expression GO:0010468 366 0.446
digestive system development GO:0055123 122 0.444
Zebrafish Mouse Rat Fly
muscle tissue development GO:0060537 1 0.433
Human Rat
nucleobase containing compound metabolic process GO:0006139 406 0.433
neurogenesis GO:0022008 236 0.424
Mouse Fly
macromolecular complex subunit organization GO:0043933 320 0.423
Zebrafish Mouse Rat Fly
positive regulation of multicellular organismal process GO:0051240 417 0.422
regulation of nucleic acid templated transcription GO:1903506 165 0.417
body morphogenesis GO:0010171 620 0.409
regulation of macromolecule metabolic process GO:0060255 421 0.407
negative regulation of multicellular organismal process GO:0051241 236 0.406
Human Mouse
generation of neurons GO:0048699 235 0.398
Mouse Fly
response to organic substance GO:0010033 131 0.398
Human Mouse Rat Fly
negative regulation of nematode larval development GO:0061064 208 0.394
tube development GO:0035295 126 0.391
Human Zebrafish Mouse Rat Fly
tissue development GO:0009888 112 0.389
Human Zebrafish Mouse Rat Fly
regulation of signal transduction GO:0009966 135 0.388
Human Zebrafish Mouse Rat Worm Fly
transport GO:0006810 1093 0.384
Human Mouse
cytoskeleton organization GO:0007010 339 0.381
Fly
negative regulation of metabolic process GO:0009892 240 0.376
Mouse Fly
developmental growth GO:0048589 412 0.375
regulation of cellular biosynthetic process GO:0031326 189 0.373
cell cycle GO:0007049 526 0.371
Human Fly
positive regulation of response to stimulus GO:0048584 55 0.365
Human Mouse Rat Worm Fly
regulation of molecular function GO:0065009 89 0.362
Human Mouse
negative regulation of post embryonic development GO:0048581 208 0.361
protein metabolic process GO:0019538 422 0.360
organic substance biosynthetic process GO:1901576 323 0.359
positive regulation of locomotion GO:0040017 42 0.355
Human
regulation of developmental process GO:0050793 684 0.348
regulation of macromolecule biosynthetic process GO:0010556 189 0.346
regulation of intracellular signal transduction GO:1902531 77 0.341
Human
reproductive structure development GO:0048608 850 0.337
Mouse Rat
protein modification process GO:0036211 207 0.335
Human Mouse Rat Fly
gene expression GO:0010467 412 0.334
developmental maturation GO:0021700 26 0.332
pattern specification process GO:0007389 59 0.331
Human Zebrafish Mouse Fly
cellular catabolic process GO:0044248 199 0.331
Fly
regulation of primary metabolic process GO:0080090 292 0.328
chemotaxis GO:0006935 120 0.326
Mouse Fly
phosphate containing compound metabolic process GO:0006796 232 0.325
Human Mouse Rat Fly
regulation of cytoplasmic transport GO:1903649 3 0.324
Human
establishment of localization GO:0051234 1171 0.323
Human Mouse
regulation of multicellular organismal development GO:2000026 317 0.322
Human Mouse Rat Fly
programmed cell death GO:0012501 500 0.315
Human Mouse Rat
locomotion GO:0040011 1634 0.314
Human Zebrafish Mouse Fly
cellular component assembly GO:0022607 293 0.313
Zebrafish Mouse Rat Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.313
intracellular signal transduction GO:0035556 96 0.309
Human Rat
macromolecule modification GO:0043412 218 0.308
Human Mouse Rat Fly
hermaphrodite genitalia development GO:0040035 734 0.301
defense response GO:0006952 296 0.300
establishment of localization in cell GO:0051649 318 0.295
Human Mouse
regulation of epithelial cell proliferation GO:0050678 1 0.295
Mouse
response to chemical GO:0042221 356 0.294
Human Mouse Rat Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.290
Mouse Fly
digestive tract morphogenesis GO:0048546 76 0.283
Zebrafish Mouse Fly
positive regulation of cellular process GO:0048522 332 0.279
genitalia development GO:0048806 741 0.275
regulation of rna metabolic process GO:0051252 173 0.274
protein complex subunit organization GO:0071822 280 0.273
Zebrafish Mouse Rat Fly
purine nucleoside metabolic process GO:0042278 92 0.264
cell migration GO:0016477 306 0.264
Human Zebrafish Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.260
phosphorylation GO:0016310 116 0.255
Human Mouse Rat Fly
regulation of cellular component organization GO:0051128 248 0.254
regulation of bmp signaling pathway GO:0030510 3 0.253
Zebrafish Mouse Worm Fly
small molecule metabolic process GO:0044281 186 0.253
macromolecule localization GO:0033036 771 0.247
regulation of cellular protein metabolic process GO:0032268 75 0.246
Human Rat Fly
cellular biosynthetic process GO:0044249 315 0.245
protein complex assembly GO:0006461 186 0.244
Zebrafish Rat
multicellular organismal reproductive behavior GO:0033057 384 0.243
Worm
positive regulation of signal transduction GO:0009967 40 0.242
Human Mouse Rat Worm Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.241
Zebrafish Mouse Fly
death GO:0016265 547 0.241
Human Mouse Rat
epithelial cell proliferation GO:0050673 1 0.239
Mouse
endocytosis GO:0006897 819 0.238
phosphorus metabolic process GO:0006793 232 0.235
Human Mouse Rat Fly
organelle organization GO:0006996 783 0.234
Fly
positive regulation of metabolic process GO:0009893 187 0.234
purine nucleoside triphosphate catabolic process GO:0009146 72 0.232
regulation of response to stimulus GO:0048583 243 0.229
Human Zebrafish Mouse Rat Worm Fly
guanosine containing compound catabolic process GO:1901069 48 0.225
muscle structure development GO:0061061 191 0.221
Human Mouse Rat Fly
positive regulation of cell communication GO:0010647 69 0.221
Human Mouse Rat Worm Fly
cell proliferation GO:0008283 116 0.219
Human Mouse Fly
oogenesis GO:0048477 229 0.217
Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.215
regulation of transcription dna templated GO:0006355 164 0.213
localization of cell GO:0051674 313 0.213
Human Zebrafish Mouse Fly
regulation of metabolic process GO:0019222 478 0.211
taxis GO:0042330 128 0.211
Mouse Fly
regulation of cell communication GO:0010646 176 0.211
Human Zebrafish Mouse Rat Worm Fly
oocyte development GO:0048599 44 0.211
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.210
Zebrafish Mouse Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.208
positive regulation of molecular function GO:0044093 61 0.206
Human
immune response GO:0006955 192 0.206
homeostatic process GO:0042592 51 0.202
Human
positive regulation of signaling GO:0023056 66 0.200
Human Mouse Rat Worm Fly
regulation of biosynthetic process GO:0009889 189 0.200
positive regulation of stem cell differentiation GO:2000738 1 0.199
meiotic cell cycle GO:0051321 335 0.194
regulation of programmed cell death GO:0043067 50 0.194
Human Mouse Rat
cellular component biogenesis GO:0044085 297 0.190
Zebrafish Mouse Rat Fly
regulation of localization GO:0032879 194 0.189
Human Mouse
positive regulation of transcription dna templated GO:0045893 102 0.183
regulation of catabolic process GO:0009894 57 0.183
receptor mediated endocytosis GO:0006898 715 0.183
response to abiotic stimulus GO:0009628 152 0.183
Rat Fly
organ morphogenesis GO:0009887 67 0.182
Human Zebrafish Mouse Fly
regulation of developmental growth GO:0048638 389 0.181
negative regulation of developmental process GO:0051093 227 0.179
Human Mouse Rat Fly
transcription dna templated GO:0006351 168 0.176
cellular nitrogen compound biosynthetic process GO:0044271 192 0.175
nucleobase containing small molecule metabolic process GO:0055086 115 0.175
cellular response to chemical stimulus GO:0070887 129 0.174
Human Mouse Rat Fly
cell death GO:0008219 547 0.173
Human Mouse Rat
cell projection morphogenesis GO:0048858 148 0.171
Mouse Fly
oocyte differentiation GO:0009994 45 0.170
reproductive system development GO:0061458 850 0.170
Mouse Rat
macromolecule catabolic process GO:0009057 202 0.168
regulation of response to wounding GO:1903034 1 0.167
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.166
positive regulation of rna metabolic process GO:0051254 103 0.165
positive regulation of macromolecule metabolic process GO:0010604 149 0.165
behavior GO:0007610 527 0.165
Worm
macromolecule biosynthetic process GO:0009059 250 0.164
regulation of protein metabolic process GO:0051246 81 0.164
regulation of cell differentiation GO:0045595 81 0.163
Human Mouse Rat Fly
stem cell differentiation GO:0048863 7 0.159
Human Mouse Fly
catabolic process GO:0009056 318 0.159
regulation of cell cycle GO:0051726 194 0.159
Fly
single organism localization GO:1902578 518 0.157
head development GO:0060322 1 0.153
Zebrafish Mouse Rat Fly
positive regulation of phosphate metabolic process GO:0045937 56 0.153
Human Rat Fly
ribonucleotide catabolic process GO:0009261 75 0.152
regulation of nervous system development GO:0051960 41 0.152
Mouse Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.150
Mouse
regulation of cellular catabolic process GO:0031329 51 0.150
Fly
regionalization GO:0003002 31 0.149
Human Zebrafish Mouse Fly
biosynthetic process GO:0009058 323 0.147
protein localization GO:0008104 205 0.146
actin filament based process GO:0030029 191 0.145
Fly
organonitrogen compound metabolic process GO:1901564 151 0.144
regulation of rna biosynthetic process GO:2001141 165 0.144
regulation of meiotic cell cycle GO:0051445 136 0.143
regulation of mapk cascade GO:0043408 23 0.142
Human
positive regulation of phosphorus metabolic process GO:0010562 56 0.141
Human Rat Fly
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.140
Mouse Fly
growth GO:0040007 562 0.140
negative regulation of gene expression GO:0010629 217 0.140
Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 112 0.139
Human Mouse Fly
embryonic pattern specification GO:0009880 21 0.136
Fly
ovulation GO:0030728 33 0.134
positive regulation of catalytic activity GO:0043085 59 0.133
Human
epidermis development GO:0008544 24 0.132
Mouse
mesoderm development GO:0007498 27 0.131
Zebrafish Mouse
rna biosynthetic process GO:0032774 169 0.131
transcription from rna polymerase ii promoter GO:0006366 149 0.130
regulation of multicellular organism growth GO:0040014 373 0.130
response to wounding GO:0009611 4 0.130
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.129
positive regulation of intracellular transport GO:0032388 2 0.127
Human
regulation of cell morphogenesis GO:0022604 40 0.126
purine ribonucleotide catabolic process GO:0009154 75 0.125
cellular protein metabolic process GO:0044267 279 0.124
Human Mouse Rat Fly
regulation of lipid metabolic process GO:0019216 4 0.121
negative regulation of macromolecule metabolic process GO:0010605 229 0.121
Mouse Fly
multi multicellular organism process GO:0044706 390 0.120
Human Rat Worm
system process GO:0003008 136 0.119
Zebrafish
vesicle mediated transport GO:0016192 852 0.118
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.115
response to other organism GO:0051707 101 0.115
epithelial tube morphogenesis GO:0060562 1 0.115
Human Zebrafish Mouse
negative regulation of cellular process GO:0048523 239 0.113
Human Zebrafish Mouse Rat Worm Fly
lipid biosynthetic process GO:0008610 28 0.112
gonad development GO:0008406 840 0.112
Mouse Rat
cell fate commitment GO:0045165 139 0.112
Human Zebrafish Mouse Fly
cell cycle process GO:0022402 482 0.112
Human
regulation of biological quality GO:0065008 741 0.112
aromatic compound catabolic process GO:0019439 116 0.111
skin development GO:0043588 24 0.111
Mouse
cellular macromolecular complex assembly GO:0034622 184 0.111
Rat
actin cytoskeleton organization GO:0030036 184 0.110
Fly
cellular ketone metabolic process GO:0042180 14 0.110
cellular component movement GO:0006928 388 0.109
Human Zebrafish Mouse Fly
axis specification GO:0009798 23 0.109
Mouse Fly
positive regulation of developmental growth GO:0048639 354 0.108
stem cell division GO:0017145 18 0.108
Fly
negative regulation of transcription dna templated GO:0045892 53 0.107
dauer larval development GO:0040024 92 0.106
nucleic acid templated transcription GO:0097659 169 0.105
regulation of apoptotic process GO:0042981 36 0.103
Human Mouse Rat
positive regulation of biosynthetic process GO:0009891 109 0.102
cellular response to endogenous stimulus GO:0071495 32 0.101
Human Mouse Rat Fly
ribonucleoside catabolic process GO:0042454 77 0.101
protein complex biogenesis GO:0070271 186 0.101
Zebrafish Rat
purine ribonucleotide metabolic process GO:0009150 95 0.100
negative regulation of response to stimulus GO:0048585 73 0.100
Human Worm Fly
regulation of cell proliferation GO:0042127 105 0.099
Human Mouse
organonitrogen compound catabolic process GO:1901565 90 0.098
response to external biotic stimulus GO:0043207 101 0.098
striated muscle cell differentiation GO:0051146 158 0.096
Human
cellular response to organic substance GO:0071310 119 0.095
Human Mouse Rat Fly
single organism nuclear import GO:1902593 6 0.095
Human
positive regulation of gene expression GO:0010628 112 0.094
cell cell signaling GO:0007267 118 0.093
Mouse Fly
macromolecular complex assembly GO:0065003 193 0.093
Zebrafish Rat
regulation of organ growth GO:0046620 5 0.093
Fly
cell projection assembly GO:0030031 35 0.092
Mouse
protein phosphorylation GO:0006468 85 0.092
Human Mouse Rat Fly
regulation of catalytic activity GO:0050790 78 0.091
Human
regulation of cellular response to growth factor stimulus GO:0090287 11 0.091
Fly
tube morphogenesis GO:0035239 79 0.090
Human Zebrafish Mouse Fly
cellular protein localization GO:0034613 75 0.090
rna metabolic process GO:0016070 228 0.090
nucleotide catabolic process GO:0009166 77 0.089
positive regulation of phosphorylation GO:0042327 27 0.089
Human Rat Fly
positive regulation of mapk cascade GO:0043410 14 0.089
Human
microtubule based process GO:0007017 182 0.089
signal transduction by phosphorylation GO:0023014 31 0.088
Human Rat
axonogenesis GO:0007409 102 0.088
Mouse Fly
cell type specific apoptotic process GO:0097285 4 0.087
regulation of growth GO:0040008 409 0.087
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.087
regulation of protein localization GO:0032880 50 0.086
Human
oocyte construction GO:0007308 2 0.086
small gtpase mediated signal transduction GO:0007264 32 0.085
purine ribonucleoside catabolic process GO:0046130 75 0.085
multicellular organism growth GO:0035264 385 0.085
axon guidance GO:0007411 82 0.085
Mouse Fly
nucleoside triphosphate catabolic process GO:0009143 72 0.084
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.083
regulation of cell cycle process GO:0010564 145 0.083
glycosyl compound metabolic process GO:1901657 100 0.083
regulation of cell migration GO:0030334 55 0.081
Human
organophosphate catabolic process GO:0046434 81 0.081
rho protein signal transduction GO:0007266 2 0.081
carboxylic acid metabolic process GO:0019752 34 0.080
purine containing compound catabolic process GO:0072523 75 0.079
heterocycle catabolic process GO:0046700 119 0.079
digestive tract development GO:0048565 122 0.078
Zebrafish Mouse Rat Fly
lipid metabolic process GO:0006629 77 0.078
positive regulation of protein metabolic process GO:0051247 45 0.077
positive regulation of multicellular organism growth GO:0040018 352 0.077
single organism transport GO:0044765 447 0.077
Human Mouse
lipid localization GO:0010876 573 0.077
Mouse
positive regulation of cell cycle GO:0045787 55 0.076
purine nucleotide catabolic process GO:0006195 75 0.076
ras protein signal transduction GO:0007265 31 0.076
negative regulation of cellular metabolic process GO:0031324 95 0.075
Fly
regulation of lipid biosynthetic process GO:0046890 1 0.075
multi organism reproductive behavior GO:0044705 387 0.075
Worm
purine ribonucleoside metabolic process GO:0046128 92 0.075
carbohydrate derivative catabolic process GO:1901136 82 0.075
oviposition GO:0018991 364 0.075
Worm
regulation of anatomical structure size GO:0090066 46 0.074
Zebrafish
organelle assembly GO:0070925 214 0.072
nucleotide metabolic process GO:0009117 108 0.072
regulation of phosphate metabolic process GO:0019220 81 0.072
Human Rat Fly
positive regulation of developmental process GO:0051094 408 0.071
regulation of cell projection assembly GO:0060491 3 0.071
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.071
regulation of mitotic cell cycle GO:0007346 76 0.071
Fly
maintenance of location GO:0051235 580 0.070
carbohydrate derivative metabolic process GO:1901135 141 0.070
cell division GO:0051301 262 0.070
Fly
regulation of cell death GO:0010941 65 0.069
Human Mouse Rat
regulation of phosphorylation GO:0042325 45 0.069
Human Rat Fly
single organism catabolic process GO:0044712 129 0.069
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.069
ribose phosphate metabolic process GO:0019693 99 0.069
guanosine containing compound metabolic process GO:1901068 49 0.068
monocarboxylic acid metabolic process GO:0032787 22 0.068
endodermal cell differentiation GO:0035987 18 0.067
Zebrafish Fly
wnt signaling pathway GO:0016055 27 0.067
purine nucleoside triphosphate metabolic process GO:0009144 87 0.066
positive regulation of nematode larval development GO:0061063 54 0.065
neuromuscular junction development GO:0007528 2 0.064
Fly
nucleoside phosphate metabolic process GO:0006753 108 0.064
gtp metabolic process GO:0046039 46 0.063
lipid storage GO:0019915 565 0.063
Mouse
negative regulation of cellular biosynthetic process GO:0031327 65 0.063
aging GO:0007568 812 0.063
Mouse Rat Fly
organic cyclic compound catabolic process GO:1901361 119 0.062
muscle organ development GO:0007517 26 0.062
Rat Fly
response to growth factor GO:0070848 18 0.062
Human Mouse Rat Fly
canonical wnt signaling pathway GO:0060070 3 0.061
nucleoside metabolic process GO:0009116 99 0.061
purine nucleotide metabolic process GO:0006163 95 0.061
cellular nitrogen compound catabolic process GO:0044270 119 0.061
cellular protein modification process GO:0006464 207 0.060
Human Mouse Rat Fly
actomyosin structure organization GO:0031032 154 0.060
organic substance transport GO:0071702 113 0.060
Human Mouse
cellular response to growth factor stimulus GO:0071363 18 0.059
Human Mouse Rat Fly
cellular macromolecule localization GO:0070727 75 0.059
regulation of nucleocytoplasmic transport GO:0046822 3 0.059
Human
reproductive behavior GO:0019098 387 0.059
Worm
sensory organ morphogenesis GO:0090596 2 0.059
Fly
oxoacid metabolic process GO:0043436 47 0.058
regulation of cellular localization GO:0060341 42 0.058
Human Mouse
secretion by cell GO:0032940 138 0.058
Mouse
copulation GO:0007620 2 0.058
memory GO:0007613 3 0.057
cell maturation GO:0048469 26 0.057
ribonucleoside triphosphate catabolic process GO:0009203 72 0.056
single organism biosynthetic process GO:0044711 91 0.056
eating behavior GO:0042755 59 0.056
Worm
negative regulation of signal transduction GO:0009968 60 0.056
Human Worm Fly
stem cell proliferation GO:0072089 9 0.055
Mouse Fly
regulation of locomotion GO:0040012 161 0.055
Human
negative regulation of nucleic acid templated transcription GO:1903507 53 0.055
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.055
regulation of apoptotic signaling pathway GO:2001233 1 0.054
Human Mouse
mesodermal cell differentiation GO:0048333 15 0.054
Mouse
muscle cell differentiation GO:0042692 171 0.054
Human Mouse
meiotic cell cycle process GO:1903046 170 0.053
secretion GO:0046903 147 0.052
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.052
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.052
multi organism behavior GO:0051705 389 0.051
Worm
peptidyl tyrosine phosphorylation GO:0018108 2 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.050
negative regulation of cellular protein metabolic process GO:0032269 27 0.050
negative regulation of rna biosynthetic process GO:1902679 53 0.049
cellular amine metabolic process GO:0044106 15 0.049
regulation of cell motility GO:2000145 57 0.048
Human
regulation of phosphorus metabolic process GO:0051174 81 0.048
Human Rat Fly
striated muscle cell development GO:0055002 157 0.048
muscle cell development GO:0055001 158 0.048
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.048
cellular localization GO:0051641 360 0.048
single organism cellular localization GO:1902580 72 0.047
Human
response to osmotic stress GO:0006970 29 0.047
regulation of multicellular organismal process GO:0051239 726 0.047
ribonucleoside triphosphate metabolic process GO:0009199 87 0.047
response to bacterium GO:0009617 86 0.047
Worm Fly
posttranscriptional regulation of gene expression GO:0010608 166 0.047
mesodermal cell fate specification GO:0007501 13 0.046
Mouse
cellular protein complex assembly GO:0043623 178 0.046
Rat
regulation of cellular amine metabolic process GO:0033238 0 0.045
regulation of stem cell differentiation GO:2000736 1 0.045
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.045
negative regulation of protein metabolic process GO:0051248 27 0.045
negative regulation of biosynthetic process GO:0009890 65 0.045
protein import GO:0017038 9 0.045
Human
positive regulation of transport GO:0051050 32 0.045
Human
positive regulation of growth GO:0045927 369 0.045
synaptic transmission GO:0007268 106 0.045
Fly
purine nucleoside catabolic process GO:0006152 75 0.044
regulation of ion transport GO:0043269 39 0.044
cell part morphogenesis GO:0032990 152 0.043
Mouse Fly
glycosyl compound catabolic process GO:1901658 79 0.043
protein catabolic process GO:0030163 162 0.043
cellular response to stress GO:0033554 162 0.043
Mouse
asymmetric cell division GO:0008356 36 0.043
metal ion transport GO:0030001 49 0.042
nucleoside triphosphate metabolic process GO:0009141 87 0.042
defense response to bacterium GO:0042742 86 0.042
Worm Fly
cell growth GO:0016049 44 0.042
Human Fly
negative regulation of cell communication GO:0010648 61 0.042
Human Mouse Worm Fly
ion transmembrane transport GO:0034220 91 0.041
bmp signaling pathway GO:0030509 3 0.041
Human Zebrafish Mouse Worm Fly
organic acid metabolic process GO:0006082 47 0.041
nucleobase containing compound catabolic process GO:0034655 114 0.040
positive regulation of cellular biosynthetic process GO:0031328 109 0.040
germ line stem cell division GO:0042078 9 0.039
Fly
single organism intracellular transport GO:1902582 70 0.039
Human
regulation of anatomical structure morphogenesis GO:0022603 51 0.039
amine metabolic process GO:0009308 15 0.039
skeletal muscle organ development GO:0060538 3 0.039
Rat
cellular component assembly involved in morphogenesis GO:0010927 183 0.039
protein localization to nucleus GO:0034504 11 0.038
ribonucleotide metabolic process GO:0009259 99 0.038
negative regulation of cell death GO:0060548 21 0.038
Human Mouse
establishment of organelle localization GO:0051656 123 0.038
feeding behavior GO:0007631 70 0.037
Worm
organ growth GO:0035265 5 0.037
Fly
positive regulation of neuron differentiation GO:0045666 4 0.036
anterior posterior axis specification GO:0009948 17 0.035
Fly
muscle system process GO:0003012 43 0.035
positive regulation of neurogenesis GO:0050769 4 0.035
regulation of behavior GO:0050795 97 0.035
Worm
organelle fission GO:0048285 363 0.035
regulation of synapse assembly GO:0051963 2 0.035
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.035
small molecule biosynthetic process GO:0044283 38 0.035
regulation of organelle organization GO:0033043 164 0.035
regulation of purine nucleotide metabolic process GO:1900542 37 0.034
purine containing compound metabolic process GO:0072521 95 0.034
determination of adult lifespan GO:0008340 812 0.034
Fly
protein transport GO:0015031 45 0.034
Human
cell substrate adhesion GO:0031589 1 0.034
oocyte axis specification GO:0007309 2 0.033
positive regulation of nucleotide metabolic process GO:0045981 28 0.033
regulation of reproductive process GO:2000241 66 0.032
Human
intracellular transport GO:0046907 77 0.032
Human
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.032
positive regulation of gtpase activity GO:0043547 28 0.032
regulation of protein serine threonine kinase activity GO:0071900 18 0.032
Human
response to endogenous stimulus GO:0009719 33 0.032
Human Mouse Rat Fly
regulation of kinase activity GO:0043549 29 0.032
Human
regulation of canonical wnt signaling pathway GO:0060828 1 0.031
biological adhesion GO:0022610 21 0.031
negative regulation of cell cycle GO:0045786 53 0.031
positive regulation of catabolic process GO:0009896 38 0.031
meiotic nuclear division GO:0007126 300 0.031
positive regulation of small gtpase mediated signal transduction GO:0051057 7 0.031
regulation of cytoskeleton organization GO:0051493 41 0.030
regulation of cell division GO:0051302 142 0.030
pigmentation GO:0043473 2 0.030
transforming growth factor beta receptor signaling pathway GO:0007179 13 0.029
Human Mouse Rat Fly
negative regulation of signaling GO:0023057 61 0.029
Human Mouse Worm Fly
negative regulation of mitotic cell cycle GO:0045930 42 0.029
positive regulation of cell migration GO:0030335 3 0.029
Human
regulation of cellular component size GO:0032535 40 0.029
single organism behavior GO:0044708 83 0.029
mesoderm morphogenesis GO:0048332 24 0.029
Zebrafish Mouse
cell junction organization GO:0034330 18 0.028
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.028
intracellular receptor signaling pathway GO:0030522 2 0.028
ribonucleoside metabolic process GO:0009119 98 0.028
protein modification by small protein conjugation or removal GO:0070647 40 0.028
Human
negative regulation of rna metabolic process GO:0051253 53 0.028
regulation of response to stress GO:0080134 28 0.028
Mouse Fly
regulation of pharyngeal pumping GO:0043051 36 0.028
Worm
anterior posterior pattern specification GO:0009952 27 0.027
Zebrafish Mouse Fly
regulation of ras gtpase activity GO:0032318 21 0.027
positive regulation of intracellular protein transport GO:0090316 2 0.027
Human

sma-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.188
disease of cellular proliferation DOID:14566 0 0.188
organ system cancer DOID:0050686 0 0.188
gastrointestinal system cancer DOID:3119 0 0.039