Caenorhabditis elegans

2 known processes

got-2.1 (CELE_C44E4.3)

Protein GOT-2.1

got-2.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
reproductive system development GO:0061458 850 0.629
embryo development ending in birth or egg hatching GO:0009792 2992 0.506
meiotic chromosome segregation GO:0045132 139 0.504
developmental process involved in reproduction GO:0003006 1165 0.501
meiotic nuclear division GO:0007126 300 0.469
single organism organelle organization GO:1902589 501 0.376
embryo development GO:0009790 3052 0.373
death GO:0016265 547 0.325
ribonucleoside triphosphate metabolic process GO:0009199 87 0.313
nucleobase containing small molecule metabolic process GO:0055086 115 0.308
meiotic cell cycle process GO:1903046 170 0.291
post embryonic development GO:0009791 2152 0.286
single organism reproductive process GO:0044702 1196 0.274
meiotic cell cycle GO:0051321 335 0.262
reproductive structure development GO:0048608 850 0.254
sex differentiation GO:0007548 909 0.251
purine nucleoside metabolic process GO:0042278 92 0.228
body morphogenesis GO:0010171 620 0.228
catabolic process GO:0009056 318 0.225
Human
development of primary sexual characteristics GO:0045137 840 0.220
purine ribonucleotide metabolic process GO:0009150 95 0.218
regulation of macromolecule metabolic process GO:0060255 421 0.207
gonad development GO:0008406 840 0.205
purine ribonucleoside metabolic process GO:0046128 92 0.198
nucleotide metabolic process GO:0009117 108 0.196
gamete generation GO:0007276 461 0.194
multicellular organismal reproductive process GO:0048609 815 0.193
chromosome segregation GO:0007059 180 0.193
purine nucleoside triphosphate metabolic process GO:0009144 87 0.183
nucleoside phosphate metabolic process GO:0006753 108 0.180
programmed cell death GO:0012501 500 0.180
aging GO:0007568 812 0.180
growth GO:0040007 562 0.180
nucleic acid metabolic process GO:0090304 299 0.171
phosphate containing compound metabolic process GO:0006796 232 0.169
purine containing compound metabolic process GO:0072521 95 0.164
purine nucleotide metabolic process GO:0006163 95 0.160
organelle organization GO:0006996 783 0.156
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.152
hermaphrodite genitalia development GO:0040035 734 0.147
regulation of developmental growth GO:0048638 389 0.146
ribonucleoside metabolic process GO:0009119 98 0.146
nucleoside triphosphate metabolic process GO:0009141 87 0.145
multicellular organismal aging GO:0010259 812 0.142
nucleoside metabolic process GO:0009116 99 0.137
ribonucleotide metabolic process GO:0009259 99 0.135
single organism catabolic process GO:0044712 129 0.132
Human
cell cycle process GO:0022402 482 0.126
organ development GO:0048513 1102 0.124
glycosyl compound metabolic process GO:1901657 100 0.123
nucleobase containing compound metabolic process GO:0006139 406 0.117
regulation of multicellular organism growth GO:0040014 373 0.116
multicellular organism growth GO:0035264 385 0.115
multi organism reproductive process GO:0044703 867 0.114
organophosphate metabolic process GO:0019637 125 0.114
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.114
multicellular organism reproduction GO:0032504 819 0.113
positive regulation of multicellular organismal process GO:0051240 417 0.112
regulation of biological quality GO:0065008 741 0.112
oocyte axis specification GO:0007309 2 0.112
regulation of multicellular organismal process GO:0051239 726 0.110
mitotic cell cycle process GO:1903047 194 0.108
positive regulation of multicellular organism growth GO:0040018 352 0.108
phosphorus metabolic process GO:0006793 232 0.107
carbohydrate derivative catabolic process GO:1901136 82 0.106
determination of adult lifespan GO:0008340 812 0.105
genitalia development GO:0048806 741 0.104
regulation of mitotic cell cycle GO:0007346 76 0.097
single organism localization GO:1902578 518 0.094
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.088
aromatic compound catabolic process GO:0019439 116 0.088
nucleoside monophosphate metabolic process GO:0009123 46 0.087
positive regulation of cellular metabolic process GO:0031325 178 0.086
regulation of cellular metabolic process GO:0031323 305 0.084
translational initiation GO:0006413 2 0.084
positive regulation of growth GO:0045927 369 0.083
cell death GO:0008219 547 0.083
striated muscle cell differentiation GO:0051146 158 0.082
nucleotide catabolic process GO:0009166 77 0.080
positive regulation of metabolic process GO:0009893 187 0.080
germ cell development GO:0007281 351 0.079
response to chemical GO:0042221 356 0.079
Human
response to hermaphrodite contact GO:0034606 10 0.078
organonitrogen compound metabolic process GO:1901564 151 0.077
Human
purine ribonucleoside catabolic process GO:0046130 75 0.077
synaptonemal complex assembly GO:0007130 6 0.077
maintenance of location GO:0051235 580 0.077
purine ribonucleotide catabolic process GO:0009154 75 0.075
ribose phosphate metabolic process GO:0019693 99 0.074
multicellular organismal reproductive behavior GO:0033057 384 0.074
lipid localization GO:0010876 573 0.074
Human
vulval development GO:0040025 333 0.074
carbohydrate derivative metabolic process GO:1901135 141 0.074
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.073
macromolecular complex assembly GO:0065003 193 0.071
macromolecule localization GO:0033036 771 0.070
Human
cell development GO:0048468 696 0.068
cellular nitrogen compound catabolic process GO:0044270 119 0.068
positive regulation of developmental process GO:0051094 408 0.066
apoptotic process GO:0006915 478 0.066
behavior GO:0007610 527 0.066
nucleoside catabolic process GO:0009164 78 0.065
post embryonic organ development GO:0048569 336 0.064
biosynthetic process GO:0009058 323 0.064
organelle assembly GO:0070925 214 0.064
muscle cell development GO:0055001 158 0.063
negative regulation of vulval development GO:0040027 206 0.062
lipid storage GO:0019915 565 0.062
negative regulation of nematode larval development GO:0061064 208 0.061
cellular catabolic process GO:0044248 199 0.059
Human
macromolecular complex subunit organization GO:0043933 320 0.058
positive regulation of cellular process GO:0048522 332 0.057
female gamete generation GO:0007292 254 0.057
purine nucleoside catabolic process GO:0006152 75 0.057
chromosome organization involved in meiosis GO:0070192 25 0.056
purine nucleoside triphosphate catabolic process GO:0009146 72 0.056
developmental growth GO:0048589 412 0.055
locomotion GO:0040011 1634 0.054
signaling GO:0023052 401 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.052
dna metabolic process GO:0006259 74 0.051
pole plasm assembly GO:0007315 2 0.050
protein localization GO:0008104 205 0.050
signal transduction GO:0007165 317 0.050
cellular component assembly GO:0022607 293 0.049
regulation of meiotic cell cycle GO:0051445 136 0.049
protein metabolic process GO:0019538 422 0.049
positive regulation of developmental growth GO:0048639 354 0.049
muscle cell differentiation GO:0042692 171 0.049
transport GO:0006810 1093 0.048
Human
regulation of transcription dna templated GO:0006355 164 0.048
sexual reproduction GO:0019953 546 0.048
oviposition GO:0018991 364 0.047
glycosyl compound catabolic process GO:1901658 79 0.046
organelle fission GO:0048285 363 0.045
positive regulation of cell cycle GO:0045787 55 0.044
cellular protein metabolic process GO:0044267 279 0.044
regulation of developmental process GO:0050793 684 0.043
ribonucleoside triphosphate catabolic process GO:0009203 72 0.042
purine containing compound catabolic process GO:0072523 75 0.042
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.042
negative regulation of biological process GO:0048519 567 0.041
nucleoside triphosphate catabolic process GO:0009143 72 0.039
microtubule based process GO:0007017 182 0.039
reproductive behavior GO:0019098 387 0.039
regulation of growth GO:0040008 409 0.039
regulation of vulval development GO:0040028 248 0.039
negative regulation of multicellular organismal process GO:0051241 236 0.039
regulation of post embryonic development GO:0048580 260 0.038
organophosphate catabolic process GO:0046434 81 0.038
multi organism reproductive behavior GO:0044705 387 0.037
regulation of gene expression GO:0010468 366 0.037
multi organism behavior GO:0051705 389 0.036
cytoskeleton organization GO:0007010 339 0.036
gene expression GO:0010467 412 0.036
muscle structure development GO:0061061 191 0.035
regulation of nitrogen compound metabolic process GO:0051171 222 0.035
regulation of metabolic process GO:0019222 478 0.035
nucleobase containing compound biosynthetic process GO:0034654 184 0.035
regulation of phosphorus metabolic process GO:0051174 81 0.035
negative regulation of post embryonic development GO:0048581 208 0.035
synapsis GO:0007129 10 0.035
regulation of apoptotic process GO:0042981 36 0.034
oogenesis GO:0048477 229 0.034
regulation of localization GO:0032879 194 0.033
cell cycle GO:0007049 526 0.033
multi multicellular organism process GO:0044706 390 0.033
establishment of localization in cell GO:0051649 318 0.033
organic substance biosynthetic process GO:1901576 323 0.033
macromolecule catabolic process GO:0009057 202 0.032
oocyte development GO:0048599 44 0.032
positive regulation of phosphorus metabolic process GO:0010562 56 0.031
cellular nitrogen compound biosynthetic process GO:0044271 192 0.030
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.030
actomyosin structure organization GO:0031032 154 0.030
organonitrogen compound catabolic process GO:1901565 90 0.030
Human
purine nucleoside monophosphate metabolic process GO:0009126 43 0.030
ribonucleoside catabolic process GO:0042454 77 0.030
macromolecule biosynthetic process GO:0009059 250 0.029
cell division GO:0051301 262 0.028
positive regulation of cellular biosynthetic process GO:0031328 109 0.028
regionalization GO:0003002 31 0.028
cellular response to stress GO:0033554 162 0.027
ribonucleotide catabolic process GO:0009261 75 0.027
regulation of cell cycle GO:0051726 194 0.027
protein complex subunit organization GO:0071822 280 0.027
organic substance catabolic process GO:1901575 294 0.027
Human
small molecule metabolic process GO:0044281 186 0.027
Human
nervous system development GO:0007399 253 0.027
cellular biosynthetic process GO:0044249 315 0.027
regulation of cellular biosynthetic process GO:0031326 189 0.026
neurogenesis GO:0022008 236 0.026
purine nucleotide catabolic process GO:0006195 75 0.026
single organism transport GO:0044765 447 0.025
Human
ribonucleoside monophosphate metabolic process GO:0009161 45 0.025
nucleobase containing compound catabolic process GO:0034655 114 0.025
phosphorylation GO:0016310 116 0.025
regulation of nematode larval development GO:0061062 260 0.025
protein complex biogenesis GO:0070271 186 0.024
organic cyclic compound biosynthetic process GO:1901362 195 0.024
cellular component morphogenesis GO:0032989 318 0.023
regulation of response to stimulus GO:0048583 243 0.023
organic cyclic compound catabolic process GO:1901361 119 0.023
striated muscle cell development GO:0055002 157 0.023
heterocycle biosynthetic process GO:0018130 187 0.022
endocytosis GO:0006897 819 0.022
regulation of protein metabolic process GO:0051246 81 0.022
chromosome condensation GO:0030261 6 0.022
rna metabolic process GO:0016070 228 0.021
atp metabolic process GO:0046034 42 0.021
negative regulation of macromolecule metabolic process GO:0010605 229 0.021
atp catabolic process GO:0006200 27 0.020
cellular amino acid metabolic process GO:0006520 15 0.020
Human
regulation of phosphate metabolic process GO:0019220 81 0.020
oocyte differentiation GO:0009994 45 0.020
vesicle mediated transport GO:0016192 852 0.020
positive regulation of phosphate metabolic process GO:0045937 56 0.019
cellular component movement GO:0006928 388 0.019
cellular homeostasis GO:0019725 22 0.019
organic substance transport GO:0071702 113 0.018
Human
oocyte construction GO:0007308 2 0.018
negative regulation of metabolic process GO:0009892 240 0.017
regulation of catabolic process GO:0009894 57 0.017
negative regulation of developmental process GO:0051093 227 0.017
positive regulation of biosynthetic process GO:0009891 109 0.017
negative regulation of mitotic cell cycle GO:0045930 42 0.017
regulation of primary metabolic process GO:0080090 292 0.017
myofibril assembly GO:0030239 154 0.017
heterocycle catabolic process GO:0046700 119 0.017
positive regulation of macromolecule metabolic process GO:0010604 149 0.017
neuron development GO:0048666 199 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
chromosome organization GO:0051276 104 0.017
positive regulation of meiotic cell cycle GO:0051446 47 0.017
myosin filament organization GO:0031033 138 0.016
negative regulation of gene expression GO:0010629 217 0.016
male gamete generation GO:0048232 41 0.016
single organism signaling GO:0044700 401 0.016
regulation of cellular component organization GO:0051128 248 0.016
nucleoside phosphate catabolic process GO:1901292 77 0.016
spermatogenesis GO:0007283 41 0.016
myosin filament assembly GO:0031034 138 0.015
proteolysis GO:0006508 61 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
mitotic nuclear division GO:0007067 89 0.015
anterior posterior axis specification GO:0009948 17 0.015
striated muscle myosin thick filament assembly GO:0071688 138 0.014
protein complex assembly GO:0006461 186 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.014
regulation of cell communication GO:0010646 176 0.014
regulation of gene silencing GO:0060968 3 0.014
protein oligomerization GO:0051259 4 0.014
regulation of cell division GO:0051302 142 0.014
cellular macromolecular complex assembly GO:0034622 184 0.014
response to organic substance GO:0010033 131 0.014
Human
mating behavior GO:0007617 32 0.014
regulation of programmed cell death GO:0043067 50 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.014
cellular macromolecule localization GO:0070727 75 0.014
regulation of multicellular organismal development GO:2000026 317 0.014
mitotic chromosome condensation GO:0007076 3 0.013
response to wounding GO:0009611 4 0.013
transcription dna templated GO:0006351 168 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
cellular component biogenesis GO:0044085 297 0.013
intracellular signal transduction GO:0035556 96 0.013
cell projection organization GO:0030030 231 0.013
response to external stimulus GO:0009605 289 0.013
anatomical structure formation involved in morphogenesis GO:0048646 250 0.013
cellular localization GO:0051641 360 0.012
localization of cell GO:0051674 313 0.012
protein modification process GO:0036211 207 0.012
neuron projection development GO:0031175 187 0.012
negative regulation of cell cycle GO:0045786 53 0.012
mitochondrial electron transport nadh to ubiquinone GO:0006120 4 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
Human
cell type specific apoptotic process GO:0097285 4 0.011
negative regulation of cellular process GO:0048523 239 0.011
germ line stem cell division GO:0042078 9 0.011
oxoacid metabolic process GO:0043436 47 0.011
Human
feeding behavior GO:0007631 70 0.011
anterior posterior pattern specification GO:0009952 27 0.011
sex determination GO:0007530 60 0.011
purine nucleoside monophosphate catabolic process GO:0009128 28 0.011
single organism biosynthetic process GO:0044711 91 0.011
regulation of nuclear division GO:0051783 115 0.011
chemical homeostasis GO:0048878 29 0.011
head development GO:0060322 1 0.010
receptor mediated endocytosis GO:0006898 715 0.010
cell maturation GO:0048469 26 0.010
cell motility GO:0048870 313 0.010

got-2.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
congenital hypoplastic anemia DOID:1342 0 0.012
immune system disease DOID:2914 0 0.012
diamond blackfan anemia DOID:1339 0 0.012
aplastic anemia DOID:12449 0 0.012
disease of anatomical entity DOID:7 0 0.012
bone marrow disease DOID:4961 0 0.012
anemia DOID:2355 0 0.012
hematopoietic system disease DOID:74 0 0.012