Caenorhabditis elegans

56 known processes

npp-4 (CELE_Y54E5A.4)

Protein NPP-4

npp-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism reproductive process GO:0044702 1196 0.875
reproductive structure development GO:0048608 850 0.874
negative regulation of vulval development GO:0040027 206 0.857
gonad development GO:0008406 840 0.836
organelle localization GO:0051640 127 0.803
mitotic cell cycle process GO:1903047 194 0.770
body morphogenesis GO:0010171 620 0.741
post embryonic development GO:0009791 2152 0.722
regulation of gene expression GO:0010468 366 0.701
regulation of multicellular organismal development GO:2000026 317 0.697
genitalia development GO:0048806 741 0.696
negative regulation of nematode larval development GO:0061064 208 0.693
embryo development ending in birth or egg hatching GO:0009792 2992 0.676
regulation of nematode larval development GO:0061062 260 0.665
regulation of macromolecule metabolic process GO:0060255 421 0.635
generation of neurons GO:0048699 235 0.631
development of primary sexual characteristics GO:0045137 840 0.628
endocytosis GO:0006897 819 0.604
regulation of developmental process GO:0050793 684 0.565
negative regulation of multicellular organismal process GO:0051241 236 0.546
transport GO:0006810 1093 0.530
vulval development GO:0040025 333 0.529
organelle organization GO:0006996 783 0.526
gene expression GO:0010467 412 0.496
gamete generation GO:0007276 461 0.488
negative regulation of biological process GO:0048519 567 0.487
sexual reproduction GO:0019953 546 0.479
cell development GO:0048468 696 0.473
hermaphrodite genitalia development GO:0040035 734 0.465
multicellular organism reproduction GO:0032504 819 0.463
multicellular organismal reproductive process GO:0048609 815 0.455
locomotion GO:0040011 1634 0.454
regulation of vulval development GO:0040028 248 0.443
reproductive system development GO:0061458 850 0.437
embryo development GO:0009790 3052 0.436
axon development GO:0061564 163 0.435
developmental process involved in reproduction GO:0003006 1165 0.428
sex differentiation GO:0007548 909 0.422
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.407
establishment of localization GO:0051234 1171 0.386
organ development GO:0048513 1102 0.380
regulation of post embryonic development GO:0048580 260 0.373
negative regulation of post embryonic development GO:0048581 208 0.371
regulation of cell differentiation GO:0045595 81 0.342
regulation of metabolic process GO:0019222 478 0.336
negative regulation of metabolic process GO:0009892 240 0.332
germ cell development GO:0007281 351 0.327
negative regulation of macromolecule metabolic process GO:0010605 229 0.316
establishment of mitotic spindle orientation GO:0000132 28 0.308
vesicle mediated transport GO:0016192 852 0.291
negative regulation of developmental process GO:0051093 227 0.284
regulation of multicellular organismal process GO:0051239 726 0.280
cellular localization GO:0051641 360 0.270
negative regulation of cellular process GO:0048523 239 0.262
single organism organelle organization GO:1902589 501 0.243
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.243
neuron differentiation GO:0030182 217 0.239
cell surface receptor signaling pathway GO:0007166 149 0.235
multi organism reproductive process GO:0044703 867 0.217
neurogenesis GO:0022008 236 0.213
single organism localization GO:1902578 518 0.198
single organism signaling GO:0044700 401 0.194
negative regulation of gene expression GO:0010629 217 0.191
single organism transport GO:0044765 447 0.184
positive regulation of multicellular organismal process GO:0051240 417 0.184
cellular macromolecule biosynthetic process GO:0034645 247 0.174
multicellular organismal aging GO:0010259 812 0.164
aging GO:0007568 812 0.164
determination of adult lifespan GO:0008340 812 0.163
growth GO:0040007 562 0.157
oogenesis GO:0048477 229 0.156
organic substance biosynthetic process GO:1901576 323 0.155
macromolecule localization GO:0033036 771 0.154
post embryonic organ development GO:0048569 336 0.150
protein metabolic process GO:0019538 422 0.140
cell fate commitment GO:0045165 139 0.135
macromolecule biosynthetic process GO:0009059 250 0.132
regulation of response to stimulus GO:0048583 243 0.127
heterocycle biosynthetic process GO:0018130 187 0.123
negative regulation of biosynthetic process GO:0009890 65 0.119
establishment of spindle localization GO:0051293 51 0.115
regulation of mrna processing GO:0050684 7 0.114
establishment of organelle localization GO:0051656 123 0.114
neuron development GO:0048666 199 0.113
regulation of mitotic cell cycle GO:0007346 76 0.113
anatomical structure formation involved in morphogenesis GO:0048646 250 0.112
cell cycle GO:0007049 526 0.108
positive regulation of developmental process GO:0051094 408 0.107
regulation of biological quality GO:0065008 741 0.106
oviposition GO:0018991 364 0.102
negative regulation of cellular metabolic process GO:0031324 95 0.101
establishment of localization in cell GO:0051649 318 0.101
regulation of cell communication GO:0010646 176 0.100
apoptotic process GO:0006915 478 0.100
nervous system development GO:0007399 253 0.099
posttranscriptional regulation of gene expression GO:0010608 166 0.098
biosynthetic process GO:0009058 323 0.096
molting cycle GO:0042303 281 0.091
nucleobase containing compound biosynthetic process GO:0034654 184 0.091
cellular biosynthetic process GO:0044249 315 0.090
signal transduction GO:0007165 317 0.090
regulation of growth GO:0040008 409 0.090
regulation of biosynthetic process GO:0009889 189 0.090
mrna processing GO:0006397 13 0.089
regulation of gene expression epigenetic GO:0040029 163 0.088
receptor mediated endocytosis GO:0006898 715 0.087
positive regulation of cellular process GO:0048522 332 0.087
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.086
lipid localization GO:0010876 573 0.083
regulation of localization GO:0032879 194 0.083
rna metabolic process GO:0016070 228 0.081
cell cycle process GO:0022402 482 0.079
tissue development GO:0009888 112 0.079
cellular protein metabolic process GO:0044267 279 0.078
female gamete generation GO:0007292 254 0.077
maintenance of location GO:0051235 580 0.075
neuron projection development GO:0031175 187 0.075
positive regulation of signaling GO:0023056 66 0.073
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.073
regulation of macromolecule biosynthetic process GO:0010556 189 0.072
regulation of organ morphogenesis GO:2000027 4 0.070
regulation of transport GO:0051049 91 0.070
lipid storage GO:0019915 565 0.070
epithelium development GO:0060429 68 0.068
mitotic nuclear division GO:0007067 89 0.067
transcription dna templated GO:0006351 168 0.067
organelle fission GO:0048285 363 0.066
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.065
cytoskeleton organization GO:0007010 339 0.062
signaling GO:0023052 401 0.061
negative regulation of cellular biosynthetic process GO:0031327 65 0.061
cellular component movement GO:0006928 388 0.060
developmental growth GO:0048589 412 0.060
single organism cellular localization GO:1902580 72 0.059
regulation of primary metabolic process GO:0080090 292 0.058
response to external stimulus GO:0009605 289 0.057
cellular nitrogen compound biosynthetic process GO:0044271 192 0.056
response to abiotic stimulus GO:0009628 152 0.056
digestive system development GO:0055123 122 0.056
nucleic acid templated transcription GO:0097659 169 0.056
regulation of cellular biosynthetic process GO:0031326 189 0.056
digestive tract development GO:0048565 122 0.056
protein complex assembly GO:0006461 186 0.055
regulation of rna metabolic process GO:0051252 173 0.055
regulation of transcription dna templated GO:0006355 164 0.055
cellular component morphogenesis GO:0032989 318 0.055
single organism behavior GO:0044708 83 0.054
tube development GO:0035295 126 0.053
regulation of nucleic acid templated transcription GO:1903506 165 0.052
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.051
protein localization GO:0008104 205 0.051
multi organism behavior GO:0051705 389 0.051
behavior GO:0007610 527 0.050
regulation of cellular metabolic process GO:0031323 305 0.049
establishment of mitotic spindle localization GO:0040001 41 0.048
regulation of rna biosynthetic process GO:2001141 165 0.047
cell morphogenesis involved in differentiation GO:0000904 112 0.047
sensory organ morphogenesis GO:0090596 2 0.047
muscle structure development GO:0061061 191 0.045
response to chemical GO:0042221 356 0.045
macromolecular complex subunit organization GO:0043933 320 0.043
multicellular organismal reproductive behavior GO:0033057 384 0.043
meiotic chromosome segregation GO:0045132 139 0.043
oocyte development GO:0048599 44 0.043
oocyte differentiation GO:0009994 45 0.042
multicellular organism growth GO:0035264 385 0.042
regulation of mrna metabolic process GO:1903311 7 0.042
canonical wnt signaling pathway GO:0060070 3 0.042
meiotic nuclear division GO:0007126 300 0.041
muscle cell differentiation GO:0042692 171 0.041
establishment of spindle orientation GO:0051294 34 0.041
cellular protein complex assembly GO:0043623 178 0.040
regulation of cell cycle process GO:0010564 145 0.039
negative regulation of gene expression epigenetic GO:0045814 2 0.037
embryonic morphogenesis GO:0048598 152 0.037
rna biosynthetic process GO:0032774 169 0.037
neuron projection morphogenesis GO:0048812 114 0.037
gene silencing GO:0016458 143 0.036
macromolecule modification GO:0043412 218 0.036
negative regulation of signal transduction GO:0009968 60 0.036
regulation of cellular localization GO:0060341 42 0.034
cellular response to chemical stimulus GO:0070887 129 0.034
cell cell signaling GO:0007267 118 0.034
positive regulation of multicellular organism growth GO:0040018 352 0.033
positive regulation of cellular biosynthetic process GO:0031328 109 0.033
meiotic cell cycle process GO:1903046 170 0.032
negative regulation of cell cycle GO:0045786 53 0.032
negative regulation of transcription dna templated GO:0045892 53 0.032
regulation of developmental growth GO:0048638 389 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.032
meiotic cell cycle GO:0051321 335 0.032
cellular protein modification process GO:0006464 207 0.031
organelle assembly GO:0070925 214 0.031
intracellular signal transduction GO:0035556 96 0.029
positive regulation of transport GO:0051050 32 0.029
posttranscriptional gene silencing by rna GO:0035194 143 0.028
cellular response to nutrient levels GO:0031669 13 0.027
regulation of nitrogen compound metabolic process GO:0051171 222 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.027
cell division GO:0051301 262 0.027
rna processing GO:0006396 34 0.026
regulation of signaling GO:0023051 172 0.026
cellular component biogenesis GO:0044085 297 0.025
cellular macromolecular complex assembly GO:0034622 184 0.025
regulation of signal transduction GO:0009966 135 0.025
phagocytosis GO:0006909 115 0.025
posttranscriptional gene silencing GO:0016441 143 0.025
organ morphogenesis GO:0009887 67 0.025
establishment or maintenance of cell polarity GO:0007163 63 0.025
positive regulation of developmental growth GO:0048639 354 0.024
organic cyclic compound biosynthetic process GO:1901362 195 0.024
negative regulation of nucleic acid templated transcription GO:1903507 53 0.024
cellular response to external stimulus GO:0071496 16 0.024
ribonucleoprotein complex assembly GO:0022618 4 0.023
striated muscle cell development GO:0055002 157 0.023
protein complex biogenesis GO:0070271 186 0.023
actin filament based process GO:0030029 191 0.023
reproductive behavior GO:0019098 387 0.023
regulation of cell cycle GO:0051726 194 0.023
protein modification process GO:0036211 207 0.022
regulation of organelle organization GO:0033043 164 0.022
regulation of cytoplasmic transport GO:1903649 3 0.022
striated muscle cell differentiation GO:0051146 158 0.022
aromatic compound biosynthetic process GO:0019438 192 0.021
cell death GO:0008219 547 0.021
gene silencing by rna GO:0031047 143 0.021
positive regulation of growth GO:0045927 369 0.021
inductive cell migration GO:0040039 145 0.021
regulation of multicellular organism growth GO:0040014 373 0.020
muscle cell development GO:0055001 158 0.020
male anatomical structure morphogenesis GO:0090598 78 0.020
myofibril assembly GO:0030239 154 0.020
regulation of cellular component organization GO:0051128 248 0.020
positive regulation of vulval development GO:0040026 52 0.019
phosphorylation GO:0016310 116 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.019
cellular amine metabolic process GO:0044106 15 0.019
positive regulation of intracellular transport GO:0032388 2 0.019
negative regulation of signaling GO:0023057 61 0.019
cellular component assembly involved in morphogenesis GO:0010927 183 0.019
enzyme linked receptor protein signaling pathway GO:0007167 50 0.019
positive regulation of cellular metabolic process GO:0031325 178 0.019
dna templated transcription elongation GO:0006354 1 0.018
cellular response to stress GO:0033554 162 0.018
rna interference GO:0016246 137 0.018
axonogenesis GO:0007409 102 0.018
regulation of epithelial cell proliferation GO:0050678 1 0.018
positive regulation of cell communication GO:0010647 69 0.018
cell migration GO:0016477 306 0.018
regulation of epithelial cell differentiation GO:0030856 4 0.018
cellular ketone metabolic process GO:0042180 14 0.018
cellular response to extracellular stimulus GO:0031668 16 0.018
microtubule based process GO:0007017 182 0.018
intracellular transport GO:0046907 77 0.018
axon guidance GO:0007411 82 0.018
single organism biosynthetic process GO:0044711 91 0.018
oxoacid metabolic process GO:0043436 47 0.018
regulation of locomotion GO:0040012 161 0.017
death GO:0016265 547 0.017
regulation of cellular protein metabolic process GO:0032268 75 0.017
actomyosin structure organization GO:0031032 154 0.017
striated muscle myosin thick filament assembly GO:0071688 138 0.017
response to extracellular stimulus GO:0009991 38 0.017
nucleus localization GO:0051647 55 0.017
negative regulation of response to dna damage stimulus GO:2001021 2 0.017
head development GO:0060322 1 0.016
rna localization GO:0006403 3 0.016
regulation of meiotic cell cycle GO:0051445 136 0.016
macromolecular complex assembly GO:0065003 193 0.016
regulation of canonical wnt signaling pathway GO:0060828 1 0.016
defense response GO:0006952 296 0.016
protein complex subunit organization GO:0071822 280 0.016
myosin filament assembly GO:0031034 138 0.016
multi multicellular organism process GO:0044706 390 0.016
cellular component assembly GO:0022607 293 0.016
negative regulation of protein metabolic process GO:0051248 27 0.016
secretion GO:0046903 147 0.016
cell cycle phase transition GO:0044770 19 0.015
organic acid metabolic process GO:0006082 47 0.015
catabolic process GO:0009056 318 0.015
cell morphogenesis GO:0000902 163 0.015
nucleic acid metabolic process GO:0090304 299 0.015
myosin filament organization GO:0031033 138 0.015
cell projection organization GO:0030030 231 0.015
sister chromatid segregation GO:0000819 46 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.014
protein modification by small protein conjugation or removal GO:0070647 40 0.014
cellular catabolic process GO:0044248 199 0.014
macromolecule catabolic process GO:0009057 202 0.014
mrna metabolic process GO:0016071 31 0.014
male sex differentiation GO:0046661 86 0.014
chemotaxis GO:0006935 120 0.014
negative regulation of response to stimulus GO:0048585 73 0.014
regulation of neuron differentiation GO:0045664 40 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.013
neuron recognition GO:0008038 83 0.013
pharynx development GO:0060465 51 0.013
regulation of cell proliferation GO:0042127 105 0.013
regulation of mrna splicing via spliceosome GO:0048024 7 0.013
positive regulation of catalytic activity GO:0043085 59 0.013
cellular macromolecule localization GO:0070727 75 0.013
positive regulation of mitochondrion organization GO:0010822 1 0.013
regulation of cell development GO:0060284 49 0.013
cellular response to organic substance GO:0071310 119 0.013
positive regulation of metabolic process GO:0009893 187 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
cell projection morphogenesis GO:0048858 148 0.013
nuclear migration GO:0007097 54 0.013
alternative mrna splicing via spliceosome GO:0000380 7 0.012
multi organism reproductive behavior GO:0044705 387 0.012
cell part morphogenesis GO:0032990 152 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
negative regulation of cell communication GO:0010648 61 0.012
positive regulation of gene expression GO:0010628 112 0.012
male gamete generation GO:0048232 41 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.012
negative regulation of mitotic cell cycle GO:0045930 42 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
apoptotic cell clearance GO:0043277 111 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 8 0.012
negative regulation of rna biosynthetic process GO:1902679 53 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.012
protein catabolic process GO:0030163 162 0.012
spermatogenesis GO:0007283 41 0.012
response to starvation GO:0042594 26 0.012
spindle localization GO:0051653 51 0.011
lipid metabolic process GO:0006629 77 0.011
regulation of cell death GO:0010941 65 0.011
germ line sex determination GO:0018992 51 0.011
organic substance catabolic process GO:1901575 294 0.011
cellular response to starvation GO:0009267 13 0.011
actin cytoskeleton organization GO:0030036 184 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.011
wnt signaling pathway GO:0016055 27 0.011
oocyte axis specification GO:0007309 2 0.011
phagocytosis engulfment GO:0006911 98 0.011
internal protein amino acid acetylation GO:0006475 3 0.011
programmed cell death GO:0012501 500 0.011
membrane invagination GO:0010324 98 0.010
nitrogen compound transport GO:0071705 49 0.010
fertilization GO:0009566 63 0.010
g1 s transition of mitotic cell cycle GO:0000082 2 0.010
negative regulation of cellular protein metabolic process GO:0032269 27 0.010
regulation of nuclear division GO:0051783 115 0.010
response to nutrient levels GO:0031667 35 0.010
cell motility GO:0048870 313 0.010
negative regulation of rna metabolic process GO:0051253 53 0.010

npp-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.023
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010
disease of anatomical entity DOID:7 0 0.010