Caenorhabditis elegans

47 known processes

npp-3 (CELE_K12D12.2)

Protein NPP-3

npp-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic cell cycle process GO:1903047 194 0.960
embryo development ending in birth or egg hatching GO:0009792 2992 0.838
embryo development GO:0009790 3052 0.759
cell cycle GO:0007049 526 0.739
single organism reproductive process GO:0044702 1196 0.723
cell cycle process GO:0022402 482 0.685
microtubule based process GO:0007017 182 0.683
post embryonic development GO:0009791 2152 0.641
developmental process involved in reproduction GO:0003006 1165 0.611
gamete generation GO:0007276 461 0.491
locomotion GO:0040011 1634 0.480
sex differentiation GO:0007548 909 0.460
gonad development GO:0008406 840 0.436
establishment of spindle localization GO:0051293 51 0.412
sexual reproduction GO:0019953 546 0.405
reproductive system development GO:0061458 850 0.395
spindle localization GO:0051653 51 0.386
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.357
organ development GO:0048513 1102 0.335
multicellular organism reproduction GO:0032504 819 0.327
hermaphrodite genitalia development GO:0040035 734 0.324
reproductive structure development GO:0048608 850 0.322
genitalia development GO:0048806 741 0.303
rna metabolic process GO:0016070 228 0.298
multicellular organismal reproductive process GO:0048609 815 0.295
mitotic spindle organization GO:0007052 81 0.271
establishment of mitotic spindle localization GO:0040001 41 0.248
development of primary sexual characteristics GO:0045137 840 0.245
meiotic cell cycle GO:0051321 335 0.241
establishment of localization in cell GO:0051649 318 0.240
receptor mediated endocytosis GO:0006898 715 0.236
regulation of cell cycle GO:0051726 194 0.226
endocytosis GO:0006897 819 0.208
spindle organization GO:0007051 92 0.199
nucleic acid metabolic process GO:0090304 299 0.198
establishment of organelle localization GO:0051656 123 0.189
nuclear pore organization GO:0006999 2 0.180
Human
nucleus organization GO:0006997 38 0.172
nucleobase containing compound metabolic process GO:0006139 406 0.166
vesicle mediated transport GO:0016192 852 0.166
regulation of metabolic process GO:0019222 478 0.166
gene expression GO:0010467 412 0.163
single organism localization GO:1902578 518 0.159
organelle fission GO:0048285 363 0.158
germ cell development GO:0007281 351 0.156
regulation of gene expression GO:0010468 366 0.155
attachment of spindle microtubules to kinetochore GO:0008608 8 0.154
cytoskeleton organization GO:0007010 339 0.153
cell development GO:0048468 696 0.151
organelle organization GO:0006996 783 0.150
regulation of cell cycle process GO:0010564 145 0.134
mitotic nuclear division GO:0007067 89 0.125
establishment of localization GO:0051234 1171 0.125
cellular component biogenesis GO:0044085 297 0.123
Human
regulation of meiotic cell cycle GO:0051445 136 0.122
positive regulation of nematode larval development GO:0061063 54 0.120
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.120
mitotic sister chromatid segregation GO:0000070 38 0.119
single organism cellular localization GO:1902580 72 0.118
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.118
cellular localization GO:0051641 360 0.118
negative regulation of cellular process GO:0048523 239 0.118
negative regulation of metabolic process GO:0009892 240 0.115
cellular component morphogenesis GO:0032989 318 0.115
sister chromatid segregation GO:0000819 46 0.107
negative regulation of vulval development GO:0040027 206 0.106
negative regulation of macromolecule metabolic process GO:0010605 229 0.101
regulation of biological quality GO:0065008 741 0.101
aromatic compound biosynthetic process GO:0019438 192 0.100
biosynthetic process GO:0009058 323 0.099
regulation of primary metabolic process GO:0080090 292 0.099
regulation of gene expression epigenetic GO:0040029 163 0.099
female gamete generation GO:0007292 254 0.097
negative regulation of gene expression GO:0010629 217 0.097
cell division GO:0051301 262 0.097
transport GO:0006810 1093 0.096
Fly
oogenesis GO:0048477 229 0.093
cellular macromolecule biosynthetic process GO:0034645 247 0.092
regulation of biosynthetic process GO:0009889 189 0.091
gene silencing by rna GO:0031047 143 0.090
single organism organelle organization GO:1902589 501 0.088
transcription from rna polymerase ii promoter GO:0006366 149 0.087
negative regulation of gene expression epigenetic GO:0045814 2 0.086
organic substance biosynthetic process GO:1901576 323 0.085
organelle localization GO:0051640 127 0.085
macromolecular complex subunit organization GO:0043933 320 0.085
Human
regulation of macromolecule biosynthetic process GO:0010556 189 0.085
regulation of macromolecule metabolic process GO:0060255 421 0.085
macromolecule localization GO:0033036 771 0.083
Fly
programmed cell death GO:0012501 500 0.082
regulation of rna biosynthetic process GO:2001141 165 0.081
rna biosynthetic process GO:0032774 169 0.078
negative regulation of biological process GO:0048519 567 0.077
regulation of transcription dna templated GO:0006355 164 0.076
macromolecular complex assembly GO:0065003 193 0.076
Human
microtubule polymerization or depolymerization GO:0031109 22 0.071
multi organism reproductive process GO:0044703 867 0.070
cell motility GO:0048870 313 0.067
cellular component movement GO:0006928 388 0.066
protein complex subunit organization GO:0071822 280 0.066
Human
regulation of nematode larval development GO:0061062 260 0.064
maintenance of location GO:0051235 580 0.063
meiotic nuclear division GO:0007126 300 0.062
heterocycle biosynthetic process GO:0018130 187 0.062
regulation of multicellular organismal process GO:0051239 726 0.062
nucleic acid templated transcription GO:0097659 169 0.061
protein localization GO:0008104 205 0.061
Fly
lipid localization GO:0010876 573 0.060
cellular component assembly GO:0022607 293 0.059
Human
lipid storage GO:0019915 565 0.058
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.057
establishment of spindle orientation GO:0051294 34 0.057
body morphogenesis GO:0010171 620 0.057
vulval development GO:0040025 333 0.053
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.053
cell migration GO:0016477 306 0.052
secretion by cell GO:0032940 138 0.052
cytokinesis GO:0000910 80 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.051
posttranscriptional regulation of gene expression GO:0010608 166 0.050
molting cycle GO:0042303 281 0.049
cellular biosynthetic process GO:0044249 315 0.049
single organism behavior GO:0044708 83 0.049
regulation of multicellular organismal development GO:2000026 317 0.048
negative regulation of biosynthetic process GO:0009890 65 0.048
localization of cell GO:0051674 313 0.048
multicellular organismal aging GO:0010259 812 0.048
multicellular organism growth GO:0035264 385 0.048
catabolic process GO:0009056 318 0.047
death GO:0016265 547 0.047
negative regulation of cellular biosynthetic process GO:0031327 65 0.047
transcription dna templated GO:0006351 168 0.047
positive regulation of cellular process GO:0048522 332 0.047
single organism signaling GO:0044700 401 0.046
Fly
regulation of cellular component organization GO:0051128 248 0.046
cellular catabolic process GO:0044248 199 0.046
establishment of mitotic spindle orientation GO:0000132 28 0.045
aging GO:0007568 812 0.045
ribonucleoprotein complex assembly GO:0022618 4 0.044
regulation of developmental process GO:0050793 684 0.043
negative regulation of cellular metabolic process GO:0031324 95 0.043
regulation of vulval development GO:0040028 248 0.042
meiotic cell cycle process GO:1903046 170 0.042
neuron projection development GO:0031175 187 0.042
gene silencing GO:0016458 143 0.041
protein complex assembly GO:0006461 186 0.041
Human
response to external stimulus GO:0009605 289 0.040
Fly
regulation of meiosis GO:0040020 94 0.040
phagocytosis GO:0006909 115 0.040
cellular protein localization GO:0034613 75 0.039
Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.039
negative regulation of mitotic cell cycle GO:0045930 42 0.038
regulation of nucleic acid templated transcription GO:1903506 165 0.038
ribosome biogenesis GO:0042254 4 0.038
macromolecule biosynthetic process GO:0009059 250 0.037
posttranscriptional gene silencing GO:0016441 143 0.037
signaling GO:0023052 401 0.037
Fly
signal transduction GO:0007165 317 0.036
Fly
regulation of organelle organization GO:0033043 164 0.036
positive regulation of vulval development GO:0040026 52 0.036
determination of adult lifespan GO:0008340 812 0.036
negative regulation of developmental process GO:0051093 227 0.035
cellular protein modification process GO:0006464 207 0.035
cellular protein metabolic process GO:0044267 279 0.034
nucleobase containing compound biosynthetic process GO:0034654 184 0.034
behavior GO:0007610 527 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.033
organic cyclic compound catabolic process GO:1901361 119 0.032
meiotic chromosome segregation GO:0045132 139 0.032
posttranscriptional gene silencing by rna GO:0035194 143 0.032
cellular macromolecular complex assembly GO:0034622 184 0.032
Human
cell death GO:0008219 547 0.031
developmental growth GO:0048589 412 0.031
fertilization GO:0009566 63 0.031
muscle structure development GO:0061061 191 0.031
growth GO:0040007 562 0.031
regulation of nuclear division GO:0051783 115 0.030
organic substance catabolic process GO:1901575 294 0.030
axon development GO:0061564 163 0.030
metaphase plate congression GO:0051310 5 0.029
neurogenesis GO:0022008 236 0.029
Fly
regulation of developmental growth GO:0048638 389 0.029
positive regulation of post embryonic development GO:0048582 54 0.029
positive regulation of multicellular organismal process GO:0051240 417 0.029
pronuclear migration GO:0035046 51 0.028
positive regulation of developmental process GO:0051094 408 0.028
phosphate containing compound metabolic process GO:0006796 232 0.028
establishment of rna localization GO:0051236 3 0.027
positive regulation of developmental growth GO:0048639 354 0.027
response to abiotic stimulus GO:0009628 152 0.026
Fly
regulation of multicellular organism growth GO:0040014 373 0.026
regulation of cellular biosynthetic process GO:0031326 189 0.026
apoptotic process GO:0006915 478 0.025
intracellular transport GO:0046907 77 0.025
Fly
protein complex biogenesis GO:0070271 186 0.025
Human
regulation of cellular metabolic process GO:0031323 305 0.025
chromosome segregation GO:0007059 180 0.024
aromatic compound catabolic process GO:0019439 116 0.024
regulation of nucleocytoplasmic transport GO:0046822 3 0.024
single fertilization GO:0007338 61 0.024
neuron development GO:0048666 199 0.024
rna interference GO:0016246 137 0.024
regulation of mitosis GO:0007088 18 0.024
regulation of cytoplasmic transport GO:1903649 3 0.023
small molecule metabolic process GO:0044281 186 0.023
regulation of cell division GO:0051302 142 0.023
cellular protein complex assembly GO:0043623 178 0.023
Human
positive regulation of growth GO:0045927 369 0.023
oviposition GO:0018991 364 0.023
chromosome organization GO:0051276 104 0.022
regulation of rna metabolic process GO:0051252 173 0.022
single organism catabolic process GO:0044712 129 0.022
multicellular organismal reproductive behavior GO:0033057 384 0.022
regulation of response to stimulus GO:0048583 243 0.022
regulation of mitotic metaphase anaphase transition GO:0030071 5 0.022
negative regulation of nematode larval development GO:0061064 208 0.022
positive regulation of multicellular organism growth GO:0040018 352 0.022
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.021
cuticle development GO:0042335 100 0.021
mitotic sister chromatid separation GO:0051306 13 0.021
negative regulation of transcription dna templated GO:0045892 53 0.021
post embryonic organ development GO:0048569 336 0.021
establishment of cell polarity GO:0030010 46 0.021
heterocycle catabolic process GO:0046700 119 0.021
negative regulation of nucleic acid templated transcription GO:1903507 53 0.021
negative regulation of post embryonic development GO:0048581 208 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.020
negative regulation of multicellular organismal process GO:0051241 236 0.020
macromolecule modification GO:0043412 218 0.020
cellular nitrogen compound biosynthetic process GO:0044271 192 0.020
purine nucleoside metabolic process GO:0042278 92 0.020
nervous system development GO:0007399 253 0.020
Fly
rna localization GO:0006403 3 0.019
positive regulation of catalytic activity GO:0043085 59 0.019
establishment of chromosome localization GO:0051303 10 0.019
response to external biotic stimulus GO:0043207 101 0.019
chromosome separation GO:0051304 19 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.019
regulation of mitotic cell cycle GO:0007346 76 0.019
dna geometric change GO:0032392 3 0.019
regulation of protein metabolic process GO:0051246 81 0.018
generation of neurons GO:0048699 235 0.018
collagen and cuticulin based cuticle development GO:0040002 99 0.018
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.018
carbohydrate derivative metabolic process GO:1901135 141 0.018
regulation of growth GO:0040008 409 0.017
tissue development GO:0009888 112 0.017
response to wounding GO:0009611 4 0.017
oocyte axis specification GO:0007309 2 0.017
single organism transport GO:0044765 447 0.017
Fly
protein modification process GO:0036211 207 0.017
regulation of post embryonic development GO:0048580 260 0.017
single organism biosynthetic process GO:0044711 91 0.017
negative regulation of cell cycle GO:0045786 53 0.017
organic cyclic compound biosynthetic process GO:1901362 195 0.016
cell cycle phase transition GO:0044770 19 0.016
dna replication checkpoint GO:0000076 1 0.016
secretion GO:0046903 147 0.016
neuron differentiation GO:0030182 217 0.016
phosphorus metabolic process GO:0006793 232 0.016
response to other organism GO:0051707 101 0.016
cell proliferation GO:0008283 116 0.016
rna transport GO:0050658 3 0.016
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.016
axonal fasciculation GO:0007413 79 0.016
cell projection morphogenesis GO:0048858 148 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.015
nitrogen compound transport GO:0071705 49 0.015
tube development GO:0035295 126 0.015
oocyte development GO:0048599 44 0.015
regulation of chromosome segregation GO:0051983 20 0.015
nucleobase containing compound catabolic process GO:0034655 114 0.015
head development GO:0060322 1 0.015
dna templated transcription elongation GO:0006354 1 0.015
organonitrogen compound catabolic process GO:1901565 90 0.015
organelle assembly GO:0070925 214 0.014
multi organism behavior GO:0051705 389 0.014
neuron recognition GO:0008038 83 0.014
regulation of protein import into nucleus GO:0042306 3 0.014
cellular macromolecule localization GO:0070727 75 0.014
Fly
mrna metabolic process GO:0016071 31 0.014
positive regulation of chromosome organization GO:2001252 2 0.014
positive regulation of cellular biosynthetic process GO:0031328 109 0.014
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.014
cell projection organization GO:0030030 231 0.014
system process GO:0003008 136 0.014
germ line sex determination GO:0018992 51 0.014
purine containing compound metabolic process GO:0072521 95 0.014
sex determination GO:0007530 60 0.014
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.014
positive regulation of transcription dna templated GO:0045893 102 0.013
anatomical structure formation involved in morphogenesis GO:0048646 250 0.013
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.013
regulation of cell communication GO:0010646 176 0.013
cell morphogenesis GO:0000902 163 0.013
taxis GO:0042330 128 0.013
Fly
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
mitotic g2 m transition checkpoint GO:0044818 1 0.013
organic substance transport GO:0071702 113 0.013
Fly
g1 s transition of mitotic cell cycle GO:0000082 2 0.013
muscle cell differentiation GO:0042692 171 0.013
actin filament based process GO:0030029 191 0.013
regionalization GO:0003002 31 0.012
apoptotic cell clearance GO:0043277 111 0.012
negative regulation of rna biosynthetic process GO:1902679 53 0.012
dna metabolic process GO:0006259 74 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.012
muscle tissue development GO:0060537 1 0.012
nucleoside catabolic process GO:0009164 78 0.012
organophosphate metabolic process GO:0019637 125 0.012
nuclear migration GO:0007097 54 0.012
nucleic acid transport GO:0050657 3 0.012
nucleoside phosphate catabolic process GO:1901292 77 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.012
cellular nitrogen compound catabolic process GO:0044270 119 0.011
ribonucleoside metabolic process GO:0009119 98 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
positive regulation of cellular metabolic process GO:0031325 178 0.011
positive regulation of biosynthetic process GO:0009891 109 0.011
regulation of protein targeting GO:1903533 3 0.011
rna polyadenylation GO:0043631 3 0.011
protein phosphorylation GO:0006468 85 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
oocyte construction GO:0007308 2 0.011
regulation of mitotic spindle organization GO:0060236 3 0.011
organonitrogen compound metabolic process GO:1901564 151 0.011
organ morphogenesis GO:0009887 67 0.011
regulation of atpase activity GO:0043462 3 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.011
cell cycle g1 s phase transition GO:0044843 2 0.010
cellular response to stress GO:0033554 162 0.010
chromatin assembly GO:0031497 1 0.010
regulation of locomotion GO:0040012 161 0.010
nucleotide metabolic process GO:0009117 108 0.010
positive regulation of rna metabolic process GO:0051254 103 0.010
membrane invagination GO:0010324 98 0.010
positive regulation of protein transport GO:0051222 4 0.010
reproductive behavior GO:0019098 387 0.010
inductive cell migration GO:0040039 145 0.010
nucleoside phosphate metabolic process GO:0006753 108 0.010
actin filament based movement GO:0030048 4 0.010
embryonic morphogenesis GO:0048598 152 0.010
dna duplex unwinding GO:0032508 3 0.010
metaphase anaphase transition of cell cycle GO:0044784 15 0.010
purine ribonucleoside catabolic process GO:0046130 75 0.010
glycosyl compound catabolic process GO:1901658 79 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.010
regulation of chromatin modification GO:1903308 2 0.010

npp-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.014