Caenorhabditis elegans

26 known processes

ifb-2 (CELE_F10C1.7)

Protein IFB-2

ifb-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.792
embryo development ending in birth or egg hatching GO:0009792 2992 0.786
single organism reproductive process GO:0044702 1196 0.636
Worm Fly
development of primary sexual characteristics GO:0045137 840 0.563
Worm Fly
multi organism reproductive process GO:0044703 867 0.552
Worm Fly
establishment of localization GO:0051234 1171 0.546
Mouse Worm Fly
locomotion GO:0040011 1634 0.542
Mouse Worm
multicellular organismal reproductive process GO:0048609 815 0.523
Worm Fly
multicellular organism reproduction GO:0032504 819 0.485
Worm Fly
vesicle mediated transport GO:0016192 852 0.482
Worm
muscle organ morphogenesis GO:0048644 4 0.467
Fly
post embryonic development GO:0009791 2152 0.455
Worm
gonad development GO:0008406 840 0.443
Worm Fly
reproductive system development GO:0061458 850 0.429
Worm Fly
organ morphogenesis GO:0009887 67 0.418
Fly
transport GO:0006810 1093 0.408
Mouse Worm
gamete generation GO:0007276 461 0.399
Worm Fly
body morphogenesis GO:0010171 620 0.379
Worm
organ development GO:0048513 1102 0.378
Human Mouse Worm Fly
multi organism reproductive behavior GO:0044705 387 0.375
Worm
behavior GO:0007610 527 0.357
Worm Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.345
Worm
regulation of multicellular organismal process GO:0051239 726 0.325
developmental process involved in reproduction GO:0003006 1165 0.309
Worm Fly
regulation of developmental process GO:0050793 684 0.282
reproductive structure development GO:0048608 850 0.276
Worm Fly
multicellular organismal reproductive behavior GO:0033057 384 0.274
Worm
hermaphrodite genitalia development GO:0040035 734 0.257
Worm
receptor mediated endocytosis GO:0006898 715 0.255
Worm
muscle tissue development GO:0060537 1 0.254
Mouse
cellular component biogenesis GO:0044085 297 0.245
Worm Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.245
Worm
mitotic nuclear envelope reassembly GO:0007084 3 0.242
Fly
genitalia development GO:0048806 741 0.237
Worm
inductive cell migration GO:0040039 145 0.236
oviposition GO:0018991 364 0.218
Worm
sex differentiation GO:0007548 909 0.215
Worm Fly
positive regulation of multicellular organism growth GO:0040018 352 0.211
regulation of locomotion GO:0040012 161 0.203
Mouse
molting cycle GO:0042303 281 0.203
Worm
tube development GO:0035295 126 0.200
Fly
signal transduction GO:0007165 317 0.198
Mouse
organelle organization GO:0006996 783 0.198
Mouse Worm Fly
single organism transport GO:0044765 447 0.196
Mouse
innate immune response GO:0045087 190 0.191
cuticle development GO:0042335 100 0.188
Worm Fly
reproductive behavior GO:0019098 387 0.183
Worm
growth GO:0040007 562 0.180
cytoskeleton organization GO:0007010 339 0.178
Mouse Worm Fly
protein metabolic process GO:0019538 422 0.174
Worm
death GO:0016265 547 0.166
Mouse
multi multicellular organism process GO:0044706 390 0.165
Worm
positive regulation of developmental process GO:0051094 408 0.165
cell migration GO:0016477 306 0.161
Mouse
developmental growth GO:0048589 412 0.160
regulation of multicellular organism growth GO:0040014 373 0.158
single organism localization GO:1902578 518 0.156
Mouse Worm Fly
cell death GO:0008219 547 0.149
Mouse
programmed cell death GO:0012501 500 0.148
Mouse
signaling GO:0023052 401 0.143
Mouse Fly
regulation of signaling GO:0023051 172 0.142
Mouse
regulation of growth GO:0040008 409 0.142
endocytosis GO:0006897 819 0.141
Worm
cell development GO:0048468 696 0.137
Mouse Worm
macromolecule localization GO:0033036 771 0.136
Mouse Worm Fly
cellular component movement GO:0006928 388 0.134
Mouse
protein catabolic process GO:0030163 162 0.134
Worm
tube morphogenesis GO:0035239 79 0.134
Fly
catabolic process GO:0009056 318 0.132
Worm
organic cyclic compound biosynthetic process GO:1901362 195 0.128
Fly
membrane organization GO:0061024 135 0.123
Mouse Fly
cellular macromolecular complex assembly GO:0034622 184 0.122
Worm Fly
single organism organelle organization GO:1902589 501 0.122
Mouse Worm Fly
organelle assembly GO:0070925 214 0.121
Worm
negative regulation of biological process GO:0048519 567 0.120
Mouse Worm Fly
protein localization GO:0008104 205 0.119
Mouse Worm Fly
apoptotic process GO:0006915 478 0.119
Mouse
regulation of metabolic process GO:0019222 478 0.119
Mouse Fly
single organism signaling GO:0044700 401 0.116
Mouse Fly
actin filament based process GO:0030029 191 0.116
Worm Fly
regulation of macromolecule biosynthetic process GO:0010556 189 0.115
Mouse Fly
regulation of developmental growth GO:0048638 389 0.113
cellular component assembly GO:0022607 293 0.113
Worm Fly
sexual reproduction GO:0019953 546 0.113
Worm Fly
macromolecule catabolic process GO:0009057 202 0.112
Worm
microtubule based process GO:0007017 182 0.111
Mouse Fly
striated muscle cell differentiation GO:0051146 158 0.110
Mouse Worm
cell cycle process GO:0022402 482 0.103
Worm Fly
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.100
Worm
protein complex subunit organization GO:0071822 280 0.099
Worm Fly
negative regulation of gene expression epigenetic GO:0045814 2 0.096
Fly
nervous system development GO:0007399 253 0.091
Fly
organic substance catabolic process GO:1901575 294 0.090
Worm
multi organism behavior GO:0051705 389 0.089
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.088
regulation of biological quality GO:0065008 741 0.084
Fly
female gamete generation GO:0007292 254 0.083
gene expression GO:0010467 412 0.083
Fly
nucleobase containing compound metabolic process GO:0006139 406 0.081
Fly
positive regulation of growth GO:0045927 369 0.081
nuclear migration GO:0007097 54 0.080
Fly
regulation of cell cycle GO:0051726 194 0.079
Worm
tissue development GO:0009888 112 0.079
Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.078
Fly
organelle fission GO:0048285 363 0.078
Worm
positive regulation of cellular process GO:0048522 332 0.077
Human Mouse Worm
macromolecular complex assembly GO:0065003 193 0.077
Worm Fly
establishment of cell polarity GO:0030010 46 0.075
nuclear pore distribution GO:0031081 2 0.075
Worm Fly
myofibril assembly GO:0030239 154 0.074
Worm
regulation of gene expression GO:0010468 366 0.074
Mouse Fly
aging GO:0007568 812 0.074
Human Zebrafish Worm Fly
macromolecular complex subunit organization GO:0043933 320 0.073
Worm Fly
cellular component morphogenesis GO:0032989 318 0.072
Worm
cell cycle GO:0007049 526 0.072
Worm Fly
multicellular organism growth GO:0035264 385 0.070
striated muscle cell development GO:0055002 157 0.067
Mouse Worm
cell motility GO:0048870 313 0.067
Mouse
striated muscle myosin thick filament assembly GO:0071688 138 0.067
Worm
regulation of primary metabolic process GO:0080090 292 0.067
Mouse Fly
cellular component assembly involved in morphogenesis GO:0010927 183 0.066
Worm
digestive tract development GO:0048565 122 0.064
Fly
regulation of response to stimulus GO:0048583 243 0.064
Mouse
cellular protein complex assembly GO:0043623 178 0.063
Worm Fly
embryonic morphogenesis GO:0048598 152 0.063
nucleobase containing compound biosynthetic process GO:0034654 184 0.062
Fly
lipid localization GO:0010876 573 0.060
actin cytoskeleton organization GO:0030036 184 0.060
Worm Fly
digestive system development GO:0055123 122 0.059
Fly
multicellular organismal aging GO:0010259 812 0.058
Worm
regulation of cell differentiation GO:0045595 81 0.057
lipid storage GO:0019915 565 0.056
germ cell development GO:0007281 351 0.056
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.055
Mouse Fly
localization of cell GO:0051674 313 0.054
Mouse
skeletal muscle organ development GO:0060538 3 0.052
negative regulation of cellular process GO:0048523 239 0.050
Mouse Worm Fly
single organism behavior GO:0044708 83 0.049
Fly
regulation of signal transduction GO:0009966 135 0.049
Mouse
adult locomotory behavior GO:0008344 1 0.049
Fly
maintenance of location GO:0051235 580 0.048
regulation of rna biosynthetic process GO:2001141 165 0.048
Mouse Fly
gene silencing GO:0016458 143 0.048
Fly
nucleic acid templated transcription GO:0097659 169 0.048
Fly
regulation of cytoskeleton organization GO:0051493 41 0.047
Fly
oogenesis GO:0048477 229 0.046
rna biosynthetic process GO:0032774 169 0.045
Fly
collagen and cuticulin based cuticle development GO:0040002 99 0.045
Worm
adult behavior GO:0030534 3 0.045
Fly
establishment or maintenance of cell polarity GO:0007163 63 0.045
Mouse
positive regulation of developmental growth GO:0048639 354 0.044
protein complex biogenesis GO:0070271 186 0.044
Worm Fly
organelle localization GO:0051640 127 0.043
Fly
system process GO:0003008 136 0.042
Zebrafish
muscle structure development GO:0061061 191 0.042
Human Mouse Worm Fly
protein complex assembly GO:0006461 186 0.042
Worm Fly
heterocycle biosynthetic process GO:0018130 187 0.041
Fly
regulation of localization GO:0032879 194 0.039
Mouse
immune response GO:0006955 192 0.039
determination of adult lifespan GO:0008340 812 0.038
Worm
localization within membrane GO:0051668 2 0.038
Worm Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.038
Mouse
tissue morphogenesis GO:0048729 65 0.037
Fly
actomyosin structure organization GO:0031032 154 0.037
Worm
meiotic cell cycle GO:0051321 335 0.037
Worm
chromosome segregation GO:0007059 180 0.037
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.036
Mouse
regulation of mitotic cell cycle GO:0007346 76 0.036
Worm
myosin filament organization GO:0031033 138 0.036
Worm
regulation of transcription dna templated GO:0006355 164 0.036
Mouse Fly
neuron differentiation GO:0030182 217 0.035
muscle cell differentiation GO:0042692 171 0.035
Mouse Worm
myosin filament assembly GO:0031034 138 0.035
Worm
response to bacterium GO:0009617 86 0.035
chromosome organization GO:0051276 104 0.034
Fly
digestive tract morphogenesis GO:0048546 76 0.034
Fly
regulation of organelle organization GO:0033043 164 0.034
Mouse Fly
regulation of gene expression epigenetic GO:0040029 163 0.033
Fly
regulation of cellular metabolic process GO:0031323 305 0.033
Mouse Fly
regulation of actin filament polymerization GO:0030833 11 0.032
Fly
macromolecule biosynthetic process GO:0009059 250 0.032
Fly
establishment of organelle localization GO:0051656 123 0.032
Fly
regulation of cell communication GO:0010646 176 0.031
Mouse
negative regulation of gene expression GO:0010629 217 0.031
Fly
meiotic nuclear division GO:0007126 300 0.031
Worm
regulation of rna metabolic process GO:0051252 173 0.031
Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.031
Mouse Fly
response to abiotic stimulus GO:0009628 152 0.031
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.031
Fly
negative regulation of metabolic process GO:0009892 240 0.030
Fly
neuron development GO:0048666 199 0.029
muscle cell development GO:0055001 158 0.029
Mouse Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.028
Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.028
Mouse
regulation of cell motility GO:2000145 57 0.027
Mouse
negative regulation of developmental process GO:0051093 227 0.027
biosynthetic process GO:0009058 323 0.027
Fly
chromatin organization GO:0006325 32 0.027
Fly
defense response GO:0006952 296 0.027
regulation of nucleic acid templated transcription GO:1903506 165 0.026
Mouse Fly
nucleotide metabolic process GO:0009117 108 0.026
cellular nitrogen compound biosynthetic process GO:0044271 192 0.026
Fly
cell cell signaling GO:0007267 118 0.024
Fly
response to external stimulus GO:0009605 289 0.024
cellular protein localization GO:0034613 75 0.024
Mouse Worm Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.024
Fly
muscle organ development GO:0007517 26 0.024
Human Fly
organic cyclic compound catabolic process GO:1901361 119 0.023
sensory organ morphogenesis GO:0090596 2 0.023
Fly
protein complex localization GO:0031503 3 0.023
Worm Fly
regulation of protein localization GO:0032880 50 0.023
Mouse
cell surface receptor signaling pathway GO:0007166 149 0.022
Mouse
ion transport GO:0006811 113 0.022
generation of neurons GO:0048699 235 0.022
cellular biosynthetic process GO:0044249 315 0.022
Fly
regulation of apoptotic signaling pathway GO:2001233 1 0.022
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.022
Mouse Fly
dna modification GO:0006304 2 0.022
regulation of cellular component size GO:0032535 40 0.022
Fly
nucleic acid metabolic process GO:0090304 299 0.022
Fly
regulation of apoptotic process GO:0042981 36 0.021
Mouse
regulation of cellular protein metabolic process GO:0032268 75 0.021
negative regulation of multicellular organismal process GO:0051241 236 0.021
rna metabolic process GO:0016070 228 0.021
Fly
defense response to bacterium GO:0042742 86 0.021
response to external biotic stimulus GO:0043207 101 0.021
nuclear pore localization GO:0051664 2 0.021
Worm Fly
apical junction assembly GO:0043297 1 0.020
regulation of cell death GO:0010941 65 0.020
Mouse
positive regulation of metabolic process GO:0009893 187 0.020
Mouse
establishment of spindle localization GO:0051293 51 0.020
organic substance transport GO:0071702 113 0.020
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.020
Fly
establishment of mitotic spindle orientation GO:0000132 28 0.020
regulation of actin filament based process GO:0032970 22 0.019
Fly
mitotic cell cycle process GO:1903047 194 0.019
Worm Fly
nucleus organization GO:0006997 38 0.018
Mouse Worm Fly
establishment of localization in cell GO:0051649 318 0.018
Mouse Fly
synaptic target recognition GO:0008039 3 0.018
regulation of chromosome segregation GO:0051983 20 0.018
Worm
muscle fiber development GO:0048747 2 0.017
response to organic substance GO:0010033 131 0.017
cytokinesis GO:0000910 80 0.017
regulation of programmed cell death GO:0043067 50 0.017
Mouse
cellular protein modification process GO:0006464 207 0.017
mitotic nuclear division GO:0007067 89 0.017
Worm
response to other organism GO:0051707 101 0.017
cellular protein metabolic process GO:0044267 279 0.017
aromatic compound biosynthetic process GO:0019438 192 0.016
Fly
head development GO:0060322 1 0.016
negative regulation of organelle organization GO:0010639 20 0.016
Mouse
negative regulation of biosynthetic process GO:0009890 65 0.016
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.016
Mouse
apoptotic mitochondrial changes GO:0008637 2 0.015
Mouse
positive regulation of rna biosynthetic process GO:1902680 102 0.015
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.015
Mouse
inorganic cation transmembrane transport GO:0098662 46 0.015
cellular localization GO:0051641 360 0.015
Mouse Worm Fly
regulation of transport GO:0051049 91 0.015
negative regulation of cell cycle GO:0045786 53 0.015
Worm
negative regulation of rna metabolic process GO:0051253 53 0.015
Fly
cell projection organization GO:0030030 231 0.015
secretion GO:0046903 147 0.014
regulation of cellular component organization GO:0051128 248 0.014
Mouse Fly
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.014
regulation of protein complex assembly GO:0043254 12 0.014
Fly
protein polymerization GO:0051258 26 0.014
Fly
protein modification process GO:0036211 207 0.014
negative regulation of signal transduction GO:0009968 60 0.014
Mouse
nucleus localization GO:0051647 55 0.014
Fly
negative regulation of rna biosynthetic process GO:1902679 53 0.013
Fly
sarcomere organization GO:0045214 10 0.013
organic substance biosynthetic process GO:1901576 323 0.013
Fly
macromolecule modification GO:0043412 218 0.013
neurogenesis GO:0022008 236 0.013
single organism cellular localization GO:1902580 72 0.013
Mouse Worm Fly
mitochondrion organization GO:0007005 20 0.013
Mouse
negative regulation of transcription dna templated GO:0045892 53 0.013
Fly
epithelial tube morphogenesis GO:0060562 1 0.012
Fly
regulation of cell projection assembly GO:0060491 3 0.012
positive regulation of cellular metabolic process GO:0031325 178 0.012
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.012
Mouse Fly
cation homeostasis GO:0055080 20 0.012
regulation of cell proliferation GO:0042127 105 0.011
Worm
regulation of mitochondrion organization GO:0010821 1 0.011
Mouse
cell type specific apoptotic process GO:0097285 4 0.011
muscle contraction GO:0006936 43 0.011
lateral inhibition GO:0046331 3 0.011
Fly
intracellular transport GO:0046907 77 0.011
Mouse
cell fate commitment GO:0045165 139 0.011
Fly
ion transmembrane transport GO:0034220 91 0.011
response to biotic stimulus GO:0009607 101 0.011
defense response to other organism GO:0098542 100 0.011
establishment of mitotic spindle localization GO:0040001 41 0.010
response to oxygen levels GO:0070482 22 0.010
Human
negative regulation of nucleic acid templated transcription GO:1903507 53 0.010
Fly
regulation of nematode larval development GO:0061062 260 0.010
regulation of protein metabolic process GO:0051246 81 0.010

ifb-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.549
Human
congenital muscular dystrophy DOID:0050557 0 0.549
Human
muscular disease DOID:0080000 0 0.549
Human
muscular dystrophy DOID:9884 0 0.549
Human
disease of anatomical entity DOID:7 0 0.549
Human
musculoskeletal system disease DOID:17 0 0.549
Human
muscle tissue disease DOID:66 0 0.549
Human
progeria DOID:3911 0 0.185
Human
heart disease DOID:114 0 0.144
Human
cardiomyopathy DOID:0050700 0 0.144
Human
cardiovascular system disease DOID:1287 0 0.144
Human
neuromuscular disease DOID:440 0 0.057
Human
charcot marie tooth disease type 2 DOID:0050539 0 0.057
Human
charcot marie tooth disease DOID:10595 0 0.057
Human
nervous system disease DOID:863 0 0.057
Human
neuropathy DOID:870 0 0.057
Human
emery dreifuss muscular dystrophy DOID:11726 0 0.027
Human
skin disease DOID:37 0 0.023
Human
integumentary system disease DOID:16 0 0.023
Human
lipodystrophy DOID:811 0 0.018
Human
familial partial lipodystrophy DOID:0050440 0 0.018
Human
dilated cardiomyopathy DOID:12930 0 0.018
Human
intrinsic cardiomyopathy DOID:0060036 0 0.018
Human