Caenorhabditis elegans

38 known processes

egl-45 (CELE_C27D11.1)

Protein EGL-45

egl-45 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gamete generation GO:0007276 461 0.900
sexual reproduction GO:0019953 546 0.876
single fertilization GO:0007338 61 0.786
fertilization GO:0009566 63 0.711
translation GO:0006412 37 0.623
Human Yeast
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.614
embryo development GO:0009790 3052 0.599
cellular macromolecule biosynthetic process GO:0034645 247 0.598
Human Yeast
gene expression GO:0010467 412 0.597
Human Yeast
embryo development ending in birth or egg hatching GO:0009792 2992 0.551
pronuclear migration GO:0035046 51 0.514
germ cell development GO:0007281 351 0.479
single organism reproductive process GO:0044702 1196 0.468
developmental process involved in reproduction GO:0003006 1165 0.460
multicellular organism reproduction GO:0032504 819 0.447
female gamete generation GO:0007292 254 0.438
meiotic cell cycle process GO:1903046 170 0.410
cellular biosynthetic process GO:0044249 315 0.409
Human Yeast
macromolecule biosynthetic process GO:0009059 250 0.395
Human Yeast
rrna metabolic process GO:0016072 3 0.389
meiotic nuclear division GO:0007126 300 0.372
cellular protein metabolic process GO:0044267 279 0.342
Human Yeast
multi organism reproductive process GO:0044703 867 0.333
locomotion GO:0040011 1634 0.327
meiotic chromosome segregation GO:0045132 139 0.325
regulation of primary metabolic process GO:0080090 292 0.308
post embryonic development GO:0009791 2152 0.307
protein metabolic process GO:0019538 422 0.284
Human Yeast
multicellular organismal reproductive process GO:0048609 815 0.284
centrosomal and pronuclear rotation GO:0035047 6 0.274
determination of adult lifespan GO:0008340 812 0.267
organic substance biosynthetic process GO:1901576 323 0.252
Human Yeast
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.244
regulation of translation GO:0006417 19 0.207
oogenesis GO:0048477 229 0.204
meiotic cell cycle GO:0051321 335 0.203
organelle fission GO:0048285 363 0.199
regulation of biosynthetic process GO:0009889 189 0.188
regulation of gene expression GO:0010468 366 0.186
regulation of multicellular organismal process GO:0051239 726 0.176
mitotic nuclear division GO:0007067 89 0.170
positive regulation of developmental process GO:0051094 408 0.169
reproductive system development GO:0061458 850 0.169
rna biosynthetic process GO:0032774 169 0.160
rna metabolic process GO:0016070 228 0.160
organ development GO:0048513 1102 0.159
positive regulation of growth GO:0045927 369 0.157
multicellular organismal aging GO:0010259 812 0.155
multicellular organismal reproductive behavior GO:0033057 384 0.154
death GO:0016265 547 0.154
development of primary sexual characteristics GO:0045137 840 0.152
positive regulation of macromolecule metabolic process GO:0010604 149 0.152
reproductive structure development GO:0048608 850 0.151
aging GO:0007568 812 0.145
developmental growth GO:0048589 412 0.144
regulation of developmental process GO:0050793 684 0.144
transcription dna templated GO:0006351 168 0.144
mitotic cell cycle process GO:1903047 194 0.143
Fly
sex differentiation GO:0007548 909 0.142
gonad development GO:0008406 840 0.142
positive regulation of gene expression GO:0010628 112 0.140
cell death GO:0008219 547 0.139
positive regulation of cellular biosynthetic process GO:0031328 109 0.136
regulation of growth GO:0040008 409 0.136
cellular protein modification process GO:0006464 207 0.134
apoptotic process GO:0006915 478 0.133
cell division GO:0051301 262 0.126
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.123
biosynthetic process GO:0009058 323 0.122
Human Yeast
multicellular organism growth GO:0035264 385 0.122
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.110
positive regulation of developmental growth GO:0048639 354 0.109
positive regulation of cellular metabolic process GO:0031325 178 0.109
macromolecule catabolic process GO:0009057 202 0.108
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.103
genitalia development GO:0048806 741 0.102
growth GO:0040007 562 0.102
regulation of biological quality GO:0065008 741 0.101
cellular response to stress GO:0033554 162 0.099
regulation of macromolecule metabolic process GO:0060255 421 0.099
positive regulation of multicellular organismal process GO:0051240 417 0.097
body morphogenesis GO:0010171 620 0.094
nucleic acid metabolic process GO:0090304 299 0.093
regulation of macromolecule biosynthetic process GO:0010556 189 0.093
oocyte axis specification GO:0007309 2 0.091
positive regulation of multicellular organism growth GO:0040018 352 0.091
regulation of metabolic process GO:0019222 478 0.091
macromolecule localization GO:0033036 771 0.089
vesicle mediated transport GO:0016192 852 0.088
regulation of rna biosynthetic process GO:2001141 165 0.087
single organism signaling GO:0044700 401 0.086
establishment of organelle localization GO:0051656 123 0.084
regulation of developmental growth GO:0048638 389 0.082
nucleobase containing compound metabolic process GO:0006139 406 0.082
establishment of localization GO:0051234 1171 0.081
nuclear migration GO:0007097 54 0.080
organelle organization GO:0006996 783 0.079
Fly
protein modification process GO:0036211 207 0.079
hermaphrodite genitalia development GO:0040035 734 0.078
chromosome organization GO:0051276 104 0.078
regulation of protein metabolic process GO:0051246 81 0.074
regulation of cellular metabolic process GO:0031323 305 0.074
nucleic acid templated transcription GO:0097659 169 0.073
cell cycle process GO:0022402 482 0.072
Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.069
positive regulation of biosynthetic process GO:0009891 109 0.069
programmed cell death GO:0012501 500 0.068
translational initiation GO:0006413 2 0.066
Human Yeast
positive regulation of rna biosynthetic process GO:1902680 102 0.066
maintenance of location GO:0051235 580 0.066
lipid localization GO:0010876 573 0.066
transport GO:0006810 1093 0.065
cellular localization GO:0051641 360 0.064
regulation of multicellular organism growth GO:0040014 373 0.063
lipid storage GO:0019915 565 0.063
organic substance catabolic process GO:1901575 294 0.063
sister chromatid segregation GO:0000819 46 0.063
inductive cell migration GO:0040039 145 0.062
regulation of cellular protein metabolic process GO:0032268 75 0.058
chromosome segregation GO:0007059 180 0.058
single organism organelle organization GO:1902589 501 0.057
Fly
protein complex subunit organization GO:0071822 280 0.056
Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.056
cellular macromolecular complex assembly GO:0034622 184 0.055
Human
regulation of cellular biosynthetic process GO:0031326 189 0.055
cell development GO:0048468 696 0.053
microtubule based process GO:0007017 182 0.052
Fly
signaling GO:0023052 401 0.051
oviposition GO:0018991 364 0.051
positive regulation of cellular process GO:0048522 332 0.049
transcription from rna polymerase ii promoter GO:0006366 149 0.048
negative regulation of metabolic process GO:0009892 240 0.048
multi organism reproductive behavior GO:0044705 387 0.048
cell migration GO:0016477 306 0.048
response to external stimulus GO:0009605 289 0.047
protein modification by small protein conjugation or removal GO:0070647 40 0.047
nervous system development GO:0007399 253 0.047
macromolecular complex subunit organization GO:0043933 320 0.047
Human Fly
heterocycle biosynthetic process GO:0018130 187 0.046
ribosome biogenesis GO:0042254 4 0.046
single organism localization GO:1902578 518 0.045
macromolecule modification GO:0043412 218 0.045
regulation of cellular component organization GO:0051128 248 0.044
endocytosis GO:0006897 819 0.044
response to unfolded protein GO:0006986 71 0.044
cellular component assembly GO:0022607 293 0.044
Human
pole plasm assembly GO:0007315 2 0.043
protein complex assembly GO:0006461 186 0.042
regulation of cell cycle GO:0051726 194 0.041
cellular nitrogen compound biosynthetic process GO:0044271 192 0.041
regulation of rna metabolic process GO:0051252 173 0.040
molting cycle GO:0042303 281 0.040
response to chemical GO:0042221 356 0.039
regulation of nucleic acid templated transcription GO:1903506 165 0.038
protein catabolic process GO:0030163 162 0.038
protein complex biogenesis GO:0070271 186 0.037
organelle assembly GO:0070925 214 0.037
cellular response to topologically incorrect protein GO:0035967 76 0.036
negative regulation of biological process GO:0048519 567 0.036
establishment of localization in cell GO:0051649 318 0.036
organelle localization GO:0051640 127 0.035
neurogenesis GO:0022008 236 0.035
negative regulation of gene expression GO:0010629 217 0.035
anatomical structure formation involved in morphogenesis GO:0048646 250 0.034
response to endoplasmic reticulum stress GO:0034976 71 0.033
localization of cell GO:0051674 313 0.032
catabolic process GO:0009056 318 0.032
positive regulation of rna metabolic process GO:0051254 103 0.031
response to organic substance GO:0010033 131 0.031
cellular macromolecule catabolic process GO:0044265 73 0.031
ribonucleoprotein complex assembly GO:0022618 4 0.031
Human
cellular protein complex assembly GO:0043623 178 0.031
aromatic compound biosynthetic process GO:0019438 192 0.031
protein localization GO:0008104 205 0.030
cellular component biogenesis GO:0044085 297 0.029
Human
regulation of transcription dna templated GO:0006355 164 0.029
regulation of nuclear division GO:0051783 115 0.029
cellular response to unfolded protein GO:0034620 71 0.029
mitotic sister chromatid segregation GO:0000070 38 0.029
cell cycle GO:0007049 526 0.029
Fly
posttranscriptional gene silencing GO:0016441 143 0.028
oocyte construction GO:0007308 2 0.027
single organism transport GO:0044765 447 0.027
phagocytosis GO:0006909 115 0.027
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.027
receptor mediated endocytosis GO:0006898 715 0.027
cytoskeleton organization GO:0007010 339 0.026
Fly
organonitrogen compound metabolic process GO:1901564 151 0.025
behavior GO:0007610 527 0.025
response to wounding GO:0009611 4 0.025
phagocytosis engulfment GO:0006911 98 0.025
er nucleus signaling pathway GO:0006984 66 0.024
secretion by cell GO:0032940 138 0.024
membrane invagination GO:0010324 98 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.024
endoplasmic reticulum unfolded protein response GO:0030968 66 0.024
endonucleolytic cleavage involved in rrna processing GO:0000478 1 0.023
posttranscriptional regulation of gene expression GO:0010608 166 0.023
cell proliferation GO:0008283 116 0.023
cellular response to starvation GO:0009267 13 0.023
male gamete generation GO:0048232 41 0.022
regulation of nitrogen compound metabolic process GO:0051171 222 0.022
spindle organization GO:0007051 92 0.022
Fly
regulation of multicellular organismal development GO:2000026 317 0.022
phosphorus metabolic process GO:0006793 232 0.022
macromolecular complex assembly GO:0065003 193 0.022
Human
positive regulation of transcription dna templated GO:0045893 102 0.021
regulation of meiotic cell cycle GO:0051445 136 0.021
striated muscle cell development GO:0055002 157 0.021
signal transduction GO:0007165 317 0.021
axon development GO:0061564 163 0.020
regeneration GO:0031099 4 0.020
nucleus localization GO:0051647 55 0.020
regulation of cell division GO:0051302 142 0.020
cell motility GO:0048870 313 0.019
regulation of localization GO:0032879 194 0.019
intracellular signal transduction GO:0035556 96 0.018
cellular catabolic process GO:0044248 199 0.018
purine nucleoside metabolic process GO:0042278 92 0.018
establishment of nucleus localization GO:0040023 55 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.018
spermatogenesis GO:0007283 41 0.017
ncrna metabolic process GO:0034660 14 0.017
cellular component movement GO:0006928 388 0.016
regulation of cell proliferation GO:0042127 105 0.016
negative regulation of cellular protein metabolic process GO:0032269 27 0.016
modification dependent macromolecule catabolic process GO:0043632 32 0.016
neuron projection guidance GO:0097485 82 0.016
nucleobase containing compound biosynthetic process GO:0034654 184 0.016
regulation of cell cycle process GO:0010564 145 0.016
multi organism behavior GO:0051705 389 0.016
rna localization GO:0006403 3 0.016
posttranscriptional gene silencing by rna GO:0035194 143 0.015
rna methylation GO:0001510 1 0.015
head development GO:0060322 1 0.015
sensory organ morphogenesis GO:0090596 2 0.015
organ morphogenesis GO:0009887 67 0.015
phosphate containing compound metabolic process GO:0006796 232 0.015
establishment of spindle orientation GO:0051294 34 0.015
reproductive behavior GO:0019098 387 0.014
rna processing GO:0006396 34 0.014
single organism catabolic process GO:0044712 129 0.014
mitotic spindle organization GO:0007052 81 0.014
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.014
secretion GO:0046903 147 0.014
mrna metabolic process GO:0016071 31 0.014
small molecule metabolic process GO:0044281 186 0.013
myosin filament assembly GO:0031034 138 0.013
negative regulation of cellular biosynthetic process GO:0031327 65 0.013
regulation of protein localization GO:0032880 50 0.013
rna interference GO:0016246 137 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.012
cleavage involved in rrna processing GO:0000469 2 0.012
modification dependent protein catabolic process GO:0019941 32 0.012
oocyte development GO:0048599 44 0.012
germ line sex determination GO:0018992 51 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
cellular response to chemical stimulus GO:0070887 129 0.012
positive regulation of protein transport GO:0051222 4 0.012
regulation of meiosis GO:0040020 94 0.012
skeletal muscle organ development GO:0060538 3 0.011
negative regulation of protein metabolic process GO:0051248 27 0.011
cuticle development GO:0042335 100 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.011
multi multicellular organism process GO:0044706 390 0.011
positive regulation of cellular component organization GO:0051130 34 0.011
muscle cell development GO:0055001 158 0.011
neuron projection development GO:0031175 187 0.011
rrna processing GO:0006364 3 0.011
actomyosin structure organization GO:0031032 154 0.011
sex determination GO:0007530 60 0.011
bmp signaling pathway GO:0030509 3 0.011
response to topologically incorrect protein GO:0035966 82 0.011
cellular component assembly involved in morphogenesis GO:0010927 183 0.011
response to nutrient levels GO:0031667 35 0.011
response to abiotic stimulus GO:0009628 152 0.011
negative regulation of vulval development GO:0040027 206 0.011
hermaphrodite germ line sex determination GO:0040021 48 0.011
ubiquitin dependent protein catabolic process GO:0006511 32 0.011
gene silencing by rna GO:0031047 143 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.010
nucleoside triphosphate metabolic process GO:0009141 87 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
defense response GO:0006952 296 0.010
chromosome organization involved in meiosis GO:0070192 25 0.010
cell type specific apoptotic process GO:0097285 4 0.010
rna catabolic process GO:0006401 21 0.010
cellular response to nutrient levels GO:0031669 13 0.010

egl-45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.012
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011